Scopolamine impairs eyeblink conditioning in cerebellar LTD-deficient mice.

abstract：:Hemispheric (re-)organization of episodic memory functions after temporal lobe damage (TLD) was investigated by the intracarotid amobarbital procedure in patients suffering temporal lobe epilepsy. Memory of the speech-dominant left hemisphere was intact after right-sided TLD independent of the age at manifestation. In...

journal_title：Neuroreport

authors： Jokeit H,Ebner A,Holthausen H,Markowitsch HJ,Tuxhorn I

更新日期：1996-07-08 00:00:00

abstract：:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

journal_title：Neuroreport

authors： Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

更新日期：2001-06-13 00:00:00

abstract：:Neuronal network reconstruction is a pivotal determinant for functional recovery after spinal cord injury (SCI), the process of which includes synaptogenesis. Slit2 protein has been identified as a key regulator of axon regeneration and synapse formation in the vertebrate. Meanwhile, RhoA is the converging cascade of ...

journal_title：Neuroreport

authors： Li Y,Gao Y,Xu X,Shi R,Liu J,Yao W,Ke C

更新日期：2017-01-18 00:00:00

abstract：:DNA fragmentation, the hallmark of apoptosis, has been recently investigated with contradictory results in several skeletal muscle disorders. Using in situ labeling of nuclear DNA fragmentation, we have tested the possibility that apoptosis might occur in muscles from patients with mitochondrial respiratory chain defe...

journal_title：Neuroreport

authors： Monici MC,Toscano A,Girlanda P,Aguennouz M,Musumeci O,Vita G

更新日期：1998-07-13 00:00:00

abstract：:Müller cells, as the predominant glial element in the sensory retina, play a crucial role in healthy and diseased retina. Overactivation of Müller cells in response to damage is detrimental to the retina tissue. Current research shows that inhibiting glial fibrillary acidic protein (GFAP), a sensitive indicator of Mül...

journal_title：Neuroreport

authors： Wang X,Shu Q,Ni Y,Xu G

更新日期：2018-12-05 00:00:00

abstract：:Complex tones such as vowels expressed by the human voice vary both in fundamental pitch (harmonic periodicity) and spectrum shape (vowel type). Three different pitches and spectra were combined into nine auditory stimuli. Latencies of cerebral evoked potential components decreased significantly as pitch increased, wh...

journal_title：Neuroreport

authors： Ragot R,Lepaul-Ercole R

更新日期：1996-03-22 00:00:00

abstract：:EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...

journal_title：Neuroreport

authors： Suo G,Shen F,Sun B,Song H,Xu M,Wu Y

更新日期：2018-08-01 00:00:00

abstract：:The glomerular layer of the olfactory bulb contains a substantial population of dopaminergic neurons. We determined the quantity and location of D1 and D2 dopamine receptors which are the presumed targets of these neurons. Binding of the D1 selective ligand [3H]SCH23390 was slightly above background and was distribute...

journal_title：Neuroreport

authors： Nickell WT,Norman AB,Wyatt LM,Shipley MT

更新日期：1991-01-01 00:00:00

abstract：:To determine whether physical match between studied and tested items influences blood flow increases in the hippocampal formation associated with recognition memory, positron emission tomography (PET) was used to measure changes in regional cerebral blood flow while healthy volunteers made old/new judgements about lin...

journal_title：Neuroreport

authors： Schacter DL,Uecker A,Reiman E,Yun LS,Bandy D,Chen K,Cooper LA,Curran T

更新日期：1997-12-22 00:00:00

abstract：:The present study examined the effects of cocaine-regulated and amphetamine-regulated transcript peptide (CARTp) fragment 55-102, on N-methyl-D-aspartate (NMDA)-mediated nociceptive transmission in vivo and in vitro. In-vivo experiments were conducted in Sprague-Dawley rats to evaluate the effects of CARTp on thermal ...

journal_title：Neuroreport

authors： Hsun Lin H,Chiu HY,Lai CC

更新日期：2005-02-28 00:00:00

abstract：:Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...

journal_title：Neuroreport

authors： Yoon S,Choi J,Huh JW,Hwang O,Kim D

更新日期：2006-05-15 00:00:00

abstract：:Plasminogen activators (PAs) have been suggested to play a role in neuronal migration and glial cell proliferation in the developing CNS. Less is known, however, about the role of PAs in the mature nervous system. To elucidate the role of tissue type plasminogen activator (tPA) in the nervous system we used in situ hy...

journal_title：Neuroreport

authors： Yuguchi T,Kohmura E,Yamada K,Otsuki H,Sakaki T,Yamashita T,Nonaka M,Sakaguchi T,Wanaka A,Hayakawa T

更新日期：1997-01-20 00:00:00

abstract：:6-Aminonicotinamide (6-AN) is thought to inhibit the pentose phosphate pathway (PPP) since large increases in 6-phosphogluconate are observed following its administration. Immediately following 45 min i.v. infusion of [2-(13)C]glucose to controls and 6-AN-treated (50 mg/kg i.p. given 4 h previously) Sprague-Dawley rat...

journal_title：Neuroreport

authors： Tyson RL,Perron J,Sutherland GR

更新日期：2000-06-26 00:00:00

abstract：:All-night recordings of respiration, ballistocardiogram, and body movements were obtained using the static charge-sensitive bed (SCSB) and automatically analysed data were compared with sleep stages. The mean sum of eight SCSB variability parameters was lowest in slow wave sleep (SWS), higher during stage 2 (S2), and ...

journal_title：Neuroreport

authors： Kaartinen J,Erkinjutti M,Rauhala E

更新日期：1996-04-10 00:00:00

abstract：:The cellular distribution of the type VI human voltage-gated sodium channel (Type VI) was examined in selected human brain regions. Antibodies designed to be specific to rat and human Type VI were raised against a synthetic peptide from the predicted NH2-terminal of the protein, and used for an immunohistochemical inv...

journal_title：Neuroreport

authors： Whitaker W,Faull R,Waldvogel H,Plumpton C,Burbidge S,Emson P,Clare J

更新日期：1999-11-26 00:00:00

abstract：:It has been suggested that lower motor neurons containing calcium-binding proteins (CBP) may be resistant to degeneration in motor neuron disease. The testing of this hypothesis is hampered by lack of comprehensive information regarding the presence of CBPs in motor neurons. To address this shortcoming, we investigate...

journal_title：Neuroreport

authors： Fahandejsaadi A,Leung E,Rahaii R,Bu J,Geula C

更新日期：2004-03-01 00:00:00

abstract：:There is abundant psychophysical evidence in humans suggesting the existence of parallel pathways subserving different aspects of vision. However, there is little direct proof of the neural structures underlying the two pathways. We present direct anatomical evidence that in the normal human optic tract fibres are seg...

journal_title：Neuroreport

authors： Tassinari G,Campara D,Balercia G,Chilosi M,Martignoni G,Marzi CA

更新日期：1994-07-21 00:00:00

abstract：:Spatial cognition requires the integration of visual inputs with proprioceptive and vestibular information about the position of the eye, the head and the body. All these sources are used by the brain to produce multiple higher-order (e.g. egocentric) representations of space, subserving accurate spatial behaviour. Su...

journal_title：Neuroreport

authors： Pizzamiglio L,Vallar G,Doricchi F

更新日期：1995-12-29 00:00:00

abstract：:To test for the feature specificity of adaptation of auditory-cortex magnetoencephalographic N1m responses to phonemes during lipreading, we presented eight healthy volunteers with a simplified sine-wave first-formant (F1) transition shared by /ba/, /ga/, and /da/, and a continuum of second-formant (F2) transitions co...

journal_title：Neuroreport

authors： Jääskeläinen IP,Kauramäki J,Tujunen J,Sams M

更新日期：2008-01-08 00:00:00

abstract：:The trans-sialidase (TS) of Trypanosoma cruzi induces survival and differentiation of neuronal and glial cells. This mechanism underlying survival is via phosphatidylinositol 3-kinase (PI3K) but how TS promotes neuronal differentiation remained to be determined. Here we show that TS-induced neurite outgrowth in PC12 c...

journal_title：Neuroreport

authors： Chuenkova MV,Pereira MA

更新日期：2001-12-04 00:00:00

abstract：:Acid-sensing ion channels (ASICs) constitute a branch of the super-gene family of amiloride-sensitive sodium channels. So far five different ASICs have been cloned from mammalian tissues. They are activated by a drop of extracellular pH but differ with respect to effective agonist concentration, desensitization and mR...

journal_title：Neuroreport

authors： Gründer S,Geissler HS,Bässler EL,Ruppersberg JP

更新日期：2000-06-05 00:00:00

abstract：:Net-like structures surrounding several types of neurones contain glycoconjugates which are detectable by lectins specific for N-acetylgalactosamine. Wisteria floribunda agglutinin (WFA) was introduced as a further marker for the visualization of such perineuronal nets, which were also revealed in regions of the rat b...

journal_title：Neuroreport

authors： Härtig W,Brauer K,Brückner G

更新日期：1992-10-01 00:00:00

abstract：:Tau protein phosphorylation has been implicated as a main process that regulates microtubule dynamics. A large number of tau isoforms is generated by phosphorylation through the action of a diversity of kinases. We have analysed variations in tau phosphorylation by two-dimensional gel electrophoresis, where a great he...

journal_title：Neuroreport

authors： Araujo HM,Sutton R,Moura Neto V

更新日期：1994-10-27 00:00:00

abstract：:Changes of serum immunoglobulin (Ig) concentrations may occur in both brain tumours and lumbar disc diseases (LDD). The purpose of this study was to investigate the changes of pre- and post-operative serum Ig levels in brain tumours and LDDs. Serum IgG, IgA and IgM levels were measured in 127 patients with brain tumou...

journal_title：Neuroreport

authors： Yüceer N,Arasil E,Temiz C

更新日期：2000-02-07 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) administration of galanin on plasma growth hormone (GH) concentrations and its possible mechanism of action have been examined in sheep. Galanin administration icv resulted in a dose-dependent increase in plasma GH concentrations (p < 0.01). Concurrent administration of ...

journal_title：Neuroreport

authors： Spencer GS,Berry CJ,Bass JJ

更新日期：1994-01-12 00:00:00

abstract：:Production and differentiation of olfactory neurons occur in spherical, multi-neuronal aggregates that form in cultures where dissociated newborn rat nasal cells are plated on to CNS glial cells. We show here that neuronal cell bodies were primarily located in the peripheral layers of the spheres, and almost every neu...

journal_title：Neuroreport

authors： Pixley SK,Bage M,Miller D,Miller ML,Shi M,Hastings L

更新日期：1994-01-31 00:00:00

abstract：:We examined whether 53 adult non-aphasic patients with either left (22) or right temporal lobe lesions (31) demonstrate dissociable patterns of hemispheric asymmetries in category-specific word fluency tasks. The patients were asked to articulate as many appropriate words as possible within 60 or 90 s in response to s...

journal_title：Neuroreport

authors： Jokeit H,Heger R,Ebner A,Markowitsch HJ

更新日期：1998-07-13 00:00:00

abstract：:Over 30% of normal elderly people have cerebral amyloid angiopathy (CAA). Possession of APOE epsilon4 is associated with increased prevalence and severity of CAA in Alzheimer's disease (AD) and in cerebral haemorrhage. We examined CAA in relation to APOE genotype in brains from 152 people aged 60-102 years, without AD...

journal_title：Neuroreport

authors： Love S,Nicoll JA,Hughes A,Wilcock GK

更新日期：2003-08-06 00:00:00

abstract：:Adrenocorticotropic hormone (ACTH) is a member of the opiocortin family of peptides. Within the central nervous system, ACTH-synthesizing neurons are generally considered to be located within the hypothalamus and are known to be involved in the neural circuitry underlying the integration of stress responses. We now re...

journal_title：Neuroreport

authors： Güntürkün O,Deviche P

更新日期：1992-02-01 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00