Abstract:
:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulation of the head-to-sensor position and signal separation via independent component analysis. In all of five subjects this approach allowed to monitor the time evolution of DC fields (<0.1 Hz) over the left hemisphere related to complex finger movements of the right hand alternating with rest periods (30 s each). Throughout the recording period of 30 min, stable task-related DC fields were recordable in a single-trial mode, i.e. without any averaging. DC-MEG opens up the possibility of analysing non-invasively cortical DC-activity also in stroke, migraine or epilepsy patients.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio Gdoi
10.1097/00001756-200106130-00034subject
Has Abstractpub_date
2001-06-13 00:00:00pages
1689-92issue
8eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
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