Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra.

abstract：:Using NADPH-diaphorase (NADPH-d) staining as a marker for the enzyme nitric oxide synthase (NOS) we investigated the possible sites of nitric oxide (NO) synthesis in the olfactory pathways of an insect brain. Staining of frozen sections revealed NADPH-d activity in neurones and in glial cells. A cluster of intensely s...

journal_title：Neuroreport

authors： Bicker G,Hähnlein I

更新日期：1995-01-26 00:00:00

abstract：:This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...

journal_title：Neuroreport

authors： Yan H,Zhang HY,Tang XC

更新日期：2007-05-07 00:00:00

abstract：:Areas of the brain's left hemisphere involved in retrieving words with emotional connotations were studied with fMRI. Participants silently generated words from different semantic categories which evoked either words with emotional connotations or emotionally neutral words. Participants repeated emotionally neutral wo...

journal_title：Neuroreport

authors： Crosson B,Radonovich K,Sadek JR,Gökçay D,Bauer RM,Fischler IS,Cato MA,Maron L,Auerbach EJ,Browd SR,Briggs RW

更新日期：1999-08-20 00:00:00

abstract：:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

journal_title：Neuroreport

authors： Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

更新日期：2001-06-13 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:Elevations of cytosolic free Ca2+ concentration ([Ca2+]i) induced by addition of ATP have been compared in rat dorsal horn neurones in slices and after their isolation. ATP application induced in neurones in situ a rise of [Ca2+]i by 201 +/- 12 nM. In Ca2+-free external solution the rise was 156 +/- 14 nM (n = 45 of 7...

journal_title：Neuroreport

authors： Kruglikov I,Shutov L,Potapenko E,Voitenko N,Kostyuk P

更新日期：2001-11-16 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP-22) gene which results in abnormal myelination of the peripheral nervous system. However, the clinical symptoms observed in the mutant suggest abnormalities in the central nervous system. Using the Northern blot te...

journal_title：Neuroreport

authors： Bascles L,Bonnet J,Garbay B

更新日期：1994-06-02 00:00:00

abstract：:The activation of GABAB receptors hyperpolarizes 5-HT neurons and reduces cell firing. In situ hybridization showed the presence of the GABAB-RI receptor transcript in virtually all 5-HT neurons of the dorsal and median raphe nuclei (DR and MnR, respectively) whereas the GAD transcript was present mainly outside these...

journal_title：Neuroreport

authors： Abellán MT,Adell A,Honrubia MA,Mengod G,Artigas F

更新日期：2000-04-07 00:00:00

abstract：:Since the characterization of orphanin FQ (OFQ), the endogenous ligand of ORL1 receptor, much work has focused on its physiological functions. OFQ was reported to antagonize the effect of opioid-induced antinociception, although its mechanism remains obscure. In the present study, whole-cell patch clamp recording tech...

journal_title：Neuroreport

authors： Zhang M,Sun QL,Wan Y,Yao L,Yu YX,Han JS

更新日期：1998-06-22 00:00:00

abstract：:After amputation of an arm the sensory map of the body changes radically, causing the sensory input from face to 'invade' the original hand area in the brain. As a result, touching the face of the amputee evokes tactile sensations on the phantom. These sensory referrals from the face to phantom hand occur in a stable,...

journal_title：Neuroreport

authors： Ramachandran VS,Brang D,McGeoch PD

更新日期：2010-07-14 00:00:00

abstract：:Benevolence is widespread in our societies. It is defined as considering a subordinate group nicely but condescendingly, that is, with charity. Deleterious consequences for the target have been reported in the literature. In this experiment, we used functional MRI (fMRI) to identify whether being the target of (sexist...

journal_title：Neuroreport

authors： Dardenne B,Dumont M,Sarlet M,Phillips C,Balteau E,Degueldre C,Luxen A,Salmon E,Maquet P,Collette F

更新日期：2013-07-10 00:00:00

abstract：:The present study examined the effect of pre-exposure to a moderate dose of caffeine (20 mg kg-1) on the acquisition of self-administration of cocaine (0.125 mg kg-1/infusion or 0.25 mg kg-1/infusion) in the rat. Rats pre-exposed to caffeine acquired self-administration more rapidly. Furthermore, sensitization to coca...

journal_title：Neuroreport

authors： Horger BA,Wellman PJ,Morien A,Davies BT,Schenk S

更新日期：1991-01-01 00:00:00

abstract：:We earlier showed that leucine-rich glioma inactivated 3 (LGI3) colocalizes with amyloid beta peptide (Abeta) taken up by astrocytes both in vitro and in vivo, and that LGI3 accumulated with endocytosis-associated proteins in aged monkey brains. In this study, we confirmed that LGI3 localizes to the endocytic pathway ...

journal_title：Neuroreport

authors： Okabayashi S,Kimura N

更新日期：2008-08-06 00:00:00

abstract：:Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...

journal_title：Neuroreport

authors： Chao TI,Alzheimer C

更新日期：1995-09-11 00:00:00

abstract：:We present the first assessment of motion vision in childhood autism. Postural reactivity to visually perceived motion was measured in five autistic children and 12 normal controls of the same chronological age. Anteroposterior as well as total body sway occurring on a force platform in response to movements in the vi...

journal_title：Neuroreport

authors： Gepner B,Mestre D,Masson G,de Schonen S

更新日期：1995-05-30 00:00:00

abstract：:It has been widely shown that recognition memory includes two distinct retrieval processes: familiarity and recollection. Many studies have shown that recognition memory can be facilitated when there is a perceptual match between the studied and the tested items. Most event-related potential studies have explored the ...

journal_title：Neuroreport

authors： Cui X,Gao C,Zhou J,Guo C

更新日期：2016-09-28 00:00:00

abstract：:It is well established that Parkinson's disease leads to impaired learning from reward and enhanced learning from punishment. The administration of dopaminergic medications reverses this learning pattern. However, few studies have investigated the neural underpinnings of these cognitive processes. In this study, using...

journal_title：Neuroreport

authors： Argyelan M,Herzallah M,Sako W,DeLucia I,Sarpal D,Vo A,Fitzpatrick T,Moustafa AA,Eidelberg D,Gluck M

更新日期：2018-05-02 00:00:00

abstract：:Neuregulins (NRG), the only trophic factors known to support Schwann cell survival, have a potential for use in treatment of patients with chronic neuropathies. Expression of one NRG isoform, NRG-beta1, was increased in axons in the early phase of axonal degeneration in nerve biopsy specimens from patients with neurop...

journal_title：Neuroreport

authors： Oka N,Kawasaki T,Matsui M,Tachibana H,Sugita M,Akiguchi I

更新日期：2000-11-27 00:00:00

abstract：:Serotonin (5-HT) is known to reduce apoptosis and in rodent models of brain ischemia. Modulation of programmed cell death during neural development was assessed in early postnatal brains of serotonin transporter (5-HTT) knockout mice, characterized by elevated extracellular 5-HT levels. The number of apoptotic cells v...

journal_title：Neuroreport

authors： Persico AM,Baldi A,Dell'Acqua ML,Moessner R,Murphy DL,Lesch KP,Keller F

更新日期：2003-03-03 00:00:00

abstract：:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus...

journal_title：Neuroreport

authors： Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S

更新日期：1998-04-20 00:00:00

abstract：:Kisspeptin is distributed not only in brain areas for regulating reproduction but also in nuclei involved in feeding control. Whether kisspeptin alters food intake is unknown in mice. We examined how kisspeptin-10 influences feeding after intracerebroventricular injection in mice using automated monitoring. Kisspeptin...

journal_title：Neuroreport

authors： Stengel A,Wang L,Goebel-Stengel M,Taché Y

更新日期：2011-03-30 00:00:00

abstract：:The regional distribution of c-Fos expression in the brain after the administration of two tremorgenic agents was studied. In both the harmaline- and oxotremorin-treated rats, c-Fos-positive neurons were extensively distributed in the basal ganglia nuclei and the cerebellum. Additionally, in the harmaline-treated rats...

journal_title：Neuroreport

authors： Miwa H,Nishi K,Fuwa T,Mizuno Y

更新日期：2000-08-03 00:00:00

abstract：:We investigated the role of melatonin in the induction of gastric lesions induced by water immersion restraint stress or centrally administered thyrotropin-releasing hormone (TRH). Melatonin (0.1-1 ng) injected intracisternally (i.c) 30 min prior to stress dose-dependently inhibited the induction of gastric lesions by...

journal_title：Neuroreport

authors： Kato K,Murai I,Asai S,Komuro S,Matsuno Y,Matsukawa Y,Kurosaka H,Iwasaki A,Ishikawa K,Arakawa Y

更新日期：1997-07-07 00:00:00

abstract：:α-Gustducin (Gα-gust) is the α subunit of the heterotrimeric G-protein complex specific for taste receptor cells of the tongue. However, it has been shown to be present in ectopic regions, such as airways and digestive tract. Recently, Gα-gust was found within neurons in various regions of the mouse brain. In this stu...

journal_title：Neuroreport

authors： Son MJ,Hu YJ,Kim SA,Chun MH,Kim IB,Kim MS

更新日期：2011-02-16 00:00:00

abstract：:The objective of this study was to investigate the effects of long-term mental abacus calculation training (MACT) on children's spatial attention orientation. Fifteen children with intensive MACT (MACT group) and 15 children without MACT (non-MACT group) were selected. The two groups of children were matched in age, s...

journal_title：Neuroreport

authors： Liu X,Sun Y

更新日期：2017-01-01 00:00:00

abstract：:We investigated the effect of nicotine, a nicotinic agonist, and D-cycloserine (DCS, a partial glycine-B agonist of the N-methyl-D-aspartate (NMDA) receptor complex) on aging-induced defects of water maze (WM) spatial navigation in rats. Nicotine (0.3 mg kg-1, s.c.) or DCS (10 mg kg-1, i.p.) enhanced acquisition of th...

journal_title：Neuroreport

authors： Riekkinen M,Riekkinen P Jr

更新日期：1997-02-10 00:00:00

abstract：:Brain trauma induces a multitude of reactions at molecular, cellular, and tissue levels, some of which are beneficial to recovery, whereas others are detrimental. Osteopontin (OPN), a glycosylated phosphoprotein, can be found in both the soluble form and as an extracellular matrix constituent in several tissues in the...

journal_title：Neuroreport

authors： Plantman S

更新日期：2012-08-01 00:00:00

abstract：:STC-1 cells have been established as an enteroendocrine cell line from the small intestine. By monitoring the level of intracellular Ca using a calcium-imaging technique, cellular responses of intestinal STC-1 cells to compounds of five basic tastants were investigated. Although this cell line was known to respond to ...

journal_title：Neuroreport

authors： Saitoh O,Hirano A,Nishimura Y

更新日期：2007-12-03 00:00:00

abstract：:There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to the level of sentence syntax. Although birdsong can indeed have a complex structure, it lacks the combinatori...

journal_title：Neuroreport

authors： Beckers GJ,Bolhuis JJ,Okanoya K,Berwick RC

更新日期：2012-02-15 00:00:00

abstract：:Cisplatin is a widely used chemotherapeutic drug, but one of its side effects is ototoxicity. Epigenetic-related drugs, such as lysine-specific demethylase 1 (LSD1) inhibitors, have been reported to protect against cisplatin-induced hair cell loss by preventing demethylation of histone H3K4 (H3K4me2). However, the pro...

journal_title：Neuroreport

authors： Li A,He Y,Sun S,Cai C,Li H

更新日期：2015-06-17 00:00:00