GABAB-RI receptors in serotonergic neurons: effects of baclofen on 5-HT output in rat brain.

abstract：:In contrast to mechanisms mediating synaptic plasticity, the pharmacological basis of perceptual learning remains to be clarified. Here we report that a specific form of perceptual learning is influenced by GABAergic mechanisms. We induced perceptual learning by Hebbian co-activation of the skin of the tip of the righ...

journal_title：Neuroreport

authors： Dinse HR,Ragert P,Pleger B,Schwenkreis P,Tegenthoff M

更新日期：2003-09-15 00:00:00

abstract：:We have isolated a cDNA encoding an inwardly rectifying K+ channel (HH-IRK1) from human heart. The cDNA codes for a 427-amino acid protein, with two putative transmembrane domains and an H5 region. The primary structure of HH-IRK1 is homologous to that of the IRK1 channel cloned from a mouse macrophage-like cell line....

journal_title：Neuroreport

authors： Raab-Graham KF,Radeke CM,Vandenberg CA

更新日期：1994-12-20 00:00:00

abstract：:Previous event-related potential studies in Indo-European languages reported a surprising finding that failed syntactic category processing appears to block lexical-semantic integration, suggesting a functional primacy of syntax over semantics. An event-related potential experiment was conducted to test whether there ...

journal_title：Neuroreport

authors： Yu J,Zhang Y

更新日期：2008-05-07 00:00:00

abstract：:We report two functional magnetic resonance imaging experiments which reveal similarities and differences between perceptual and imaginal networks within the single visual submodality of colour. The first experiment contrasted viewing of a coloured and grey-scale Mondrian display, while the second contrasted a relativ...

journal_title：Neuroreport

authors： Howard RJ,ffytche DH,Barnes J,McKeefry D,Ha Y,Woodruff PW,Bullmore ET,Simmons A,Williams SC,David AS,Brammer M

更新日期：1998-04-20 00:00:00

abstract：:Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...

journal_title：Neuroreport

authors： Chaudhuri A

更新日期：1997-09-08 00:00:00

abstract：:Diabetic peripheral neuropathy is the most common complication of diabetes mellitus and leads to sensory symptoms, including diabetic neuropathic pain (DNP). DNP is a major public health problem because it has a considerable impact on life quality of diabetes mellitus patients. Therefore, development of novel effectiv...

journal_title：Neuroreport

authors： Li P,Xiong DL,Sun WP,Xu SY

更新日期：2018-12-05 00:00:00

abstract：:Fourteen healthy right-handed subjects were scanned using PET with a [15O]water tracer during exposure to electromagnetic field (EMF) emitted by a mobile phone and a sham-exposure under double-blind conditions. During scanning, the subjects performed a visual working memory task. Exposure to an active mobile phone pro...

journal_title：Neuroreport

authors： Haarala C,Aalto S,Hautzel H,Julkunen L,Rinne JO,Laine M,Krause B,Hämäläinen H

更新日期：2003-11-14 00:00:00

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:Currents from the slowly adapting stretch receptor neuron of the crayfish (Pacifastacus leniusculus) were studied in a cell attached configuration using patch pipettes with an opening diameter of 2-10 microm. The neuronal membrane was enzymatically freed from the glial layer. The voltage gated Na+ and K+ channels seem...

journal_title：Neuroreport

authors： Lin JH,Sand P,Rydqvist B

更新日期：1999-08-20 00:00:00

abstract：:Recently, we have generated transgenic mice (designated as SJLB) carrying human N279K mutant tau, one of the tau mutations causing parkinsonism linked to chromosome 17 (FTDP-17). SJLB mice mimic some features of behavioral alterations and neuronal pathology of patients with Alzheimer's disease. To investigate how tau ...

journal_title：Neuroreport

authors： Takano M,Otani M,Sakai A,Kadoyama K,Matsuyama S,Matsumoto A,Takenokuchi M,Sumida M,Taniguchi T

更新日期：2009-12-09 00:00:00

abstract：:Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

journal_title：Neuroreport

authors： Kempster S,Collins ME,Edington N

更新日期：2004-10-05 00:00:00

abstract：:Dysfunction of the cholinergic system of the basal forebrain complex is one of the major contributors toward cognitive impairment in Alzheimer's disease (AD). In AD, degeneration of cholinergic fibers that project to the cerebral cortex and hippocampus may be attributed to the development of neurofibrillary tangles (N...

journal_title：Neuroreport

authors： Kim JM,Kim SS,Lee YD

更新日期：2015-09-09 00:00:00

abstract：:The effects of histamine on N-methyl-d-aspartate (NMDA) receptor-mediated ion current in cultured rat cortical neurones have been investigated by superfusion of voltage-clamped (-80 mV) cells with 100 mM NMDA and with various concentrations of histamine. In a subpopulation of the neurones tested (30/53), histamine (10...

journal_title：Neuroreport

authors： Zwart R,Blank T,Spiess J

更新日期：1996-09-02 00:00:00

abstract：:The present study examined in urethane-chloralose anaesthetized rats whether N-methyl-D-aspartate (NMDA) is involved in the depressant effect of flupirtine on the monosynaptic Hoffmann (H)-reflex recorded from plantar foot muscles and on polysynaptic flexor reflexes recorded from tibialis muscle. Intrathecal administr...

journal_title：Neuroreport

authors： Schwarz M,Block F,Pergande G

更新日期：1994-10-03 00:00:00

abstract：:I have investigated the role of Ca2+ on M-current (IK(M)) inhibition by the muscarinic agonist oxo-M using the perforated patch voltage clamp technique. Oxo-M inhibited IK(M) in cultured SCG cells with an IC50 of 1.2 microM in 2 mM [Ca2+]o, and 13.1 microM in nominally Ca(2+)-free external solution. BAPTA-AM, ryanodin...

journal_title：Neuroreport

authors： Lamas JA

更新日期：1999-08-02 00:00:00

abstract：:The major central nervous system (CNS) myelin proteolipid (PLP) is also expressed in the peripheral nervous system (PNS). This paper gives evidence that DM-20, an isoform of PLP, also occurs in rat sciatic nerves, where, in contrast to what is seen in CNS myelin, it predominates over PLP. This conclusion was reached o...

journal_title：Neuroreport

authors： Pham-Dinh D,Birling MC,Roussel G,Dautigny A,Nussbaum JL

更新日期：1991-02-01 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1) channel has been found to be expressed in a variety of tissues over the last few years, including the central nervous system (CNS). However, the distribution of TRPV1 in the CNS remains a controversial question. Here, we reveal that the expression of TRPV1 can be detect...

journal_title：Neuroreport

authors： Huang WX,Min JW,Liu YQ,He XH,Peng BW

更新日期：2014-04-16 00:00:00

abstract：:The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...

journal_title：Neuroreport

authors： Hara NF,Nakamura K,Kuroki C,Takayama Y,Ogawa S

更新日期：2007-10-08 00:00:00

abstract：:Voltage-gated sodium channels (VGSCs) are concentrated in the postsynaptic membrane at the adult rat neuromuscular junction (NMJ). We have used immunolabelling to determine the pattern of initial VGSC accumulation during development. At birth, but not 3 days before, VGSC labelling is detectable at the NMJ and in the p...

journal_title：Neuroreport

authors： Wood SJ,Shewry K,Young C,Slater CR

更新日期：1998-06-22 00:00:00

abstract：:Nicotine injected in the supraoptic nucleus facilitates vasopressin release from the neurohypophysis. Nicotinic acetylcholine receptors have been found not only on vasopressin-producing cell bodies but also on presynaptic nerve terminals in the nucleus. Vasopressin cells receive excitatory synaptic inputs from noradre...

journal_title：Neuroreport

authors： Liu X,Onaka T,Yagi K

更新日期：2001-03-05 00:00:00

abstract：:When examining a buying process, changes in human brain signals and their event-related potential (ERP) components can be considered a reflection of the consumers' emotions. In this experiment, participants were shown 12 products and related services that were available for purchase. After recording ERP components, we...

journal_title：Neuroreport

authors： Zhao M,Wang J,Han W

更新日期：2015-12-02 00:00:00

abstract：:The gene expression of cholecystokinin (CCK), a neuropeptide with anti-opioid properties, has been reported to be upregulated in some primary sensory neurons after a peripheral nerve lesion. We have recently demonstrated that the upregulation of CCK mRNA is not accompanied by an increased potassium-evoked release CCK-...

journal_title：Neuroreport

authors： Afrah AW,Gustafsson H,Olgart L,Brodin E,Stiller CO

更新日期：2001-01-22 00:00:00

abstract：:The present study examined the effect of peripherally applied morphine and GABA on jaw muscle electromyographic activity reflexly evoked by co-injection of glutamate into the temporomandibular joint (TMJ) of lightly anesthetized Sprague-Dawley rats of both sexes. In male but not female rats, morphine significantly sup...

journal_title：Neuroreport

authors： Cai BB,Cairns BE,Sessle BJ,Hu JW

更新日期：2001-11-16 00:00:00

abstract：:In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...

journal_title：Neuroreport

authors： Yamada S,Nomura T,Takano K,Fujita S,Miyake M,Miyake J

更新日期：2008-11-19 00:00:00

abstract：:Müller cells, as the predominant glial element in the sensory retina, play a crucial role in healthy and diseased retina. Overactivation of Müller cells in response to damage is detrimental to the retina tissue. Current research shows that inhibiting glial fibrillary acidic protein (GFAP), a sensitive indicator of Mül...

journal_title：Neuroreport

authors： Wang X,Shu Q,Ni Y,Xu G

更新日期：2018-12-05 00:00:00

abstract：:GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...

journal_title：Neuroreport

authors： Jackson VR,Nothacker HP,Civelli O

更新日期：2006-05-29 00:00:00

abstract：:Muller glial cells of the sensory retina mediate K+ and water fluxes that are facilitated by aquaporin-4 (AQP4) water channels and by Kir4.1-K+ channels. However, it is not known which subtypes of aquaporins are expressed in the mammalian retina. Using RT-PCR, we found that both human and rat retinas express mRNA for ...

journal_title：Neuroreport

authors： Tenckhoff S,Hollborn M,Kohen L,Wolf S,Wiedemann P,Bringmann A

更新日期：2005-01-19 00:00:00

abstract：:Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...

journal_title：Neuroreport

authors： Wang H,Wang X,Scheich H

更新日期：1996-01-31 00:00:00

abstract：:Hypoxia-induced changes in intracerebral arterioles, the major determinants of local cerebral oxygen delivery, are not well understood. Hippocampal arteriolar diameters were measured in rat brain slices using computerized videomicroscopy. In group 1 (control), artificial cerebrospinal fluid oxygen tension (PO2) was ma...

journal_title：Neuroreport

authors： Staunton M,Dulitz MG,Fang C,Schmeling WT,Kampine JP,Farber NE

更新日期：1998-05-11 00:00:00

abstract：:The temperature of the tail skin is an important factor determining tail-flick latency to noxious radiant heat in rats and mice. The temperature of the skin may also be important in determining the behavioural response in the formalin test. Morphine in low and moderate doses strongly affected the core and tail skin te...

journal_title：Neuroreport

authors： Tjølsen A,Hole K

更新日期：1992-06-01 00:00:00