Abstract:
:The present study examined the effect of peripherally applied morphine and GABA on jaw muscle electromyographic activity reflexly evoked by co-injection of glutamate into the temporomandibular joint (TMJ) of lightly anesthetized Sprague-Dawley rats of both sexes. In male but not female rats, morphine significantly suppressed glutamate-evoked jaw muscle activity in a dose-dependent and naloxone-reversible manner. The median suppressive dose (+/- s.e.) for male rats was 12.7 +/- 3.1 microg (digastric muscle) and 12.6 +/- 1.3 microg (masseter muscle). GABA (5 micromol) significantly reduced glutamate-evoked muscle activity in both sexes. These data suggest that female rats are considerably less sensitive than male rats to the suppressive effects of peripherally applied morphine, but both sexes are equally affected by peripherally applied GABA.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Cai BB,Cairns BE,Sessle BJ,Hu JWdoi
10.1097/00001756-200111160-00016subject
Has Abstractpub_date
2001-11-16 00:00:00pages
3457-60issue
16eissn
0959-4965issn
1473-558Xjournal_volume
12pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::We examined whether 53 adult non-aphasic patients with either left (22) or right temporal lobe lesions (31) demonstrate dissociable patterns of hemispheric asymmetries in category-specific word fluency tasks. The patients were asked to articulate as many appropriate words as possible within 60 or 90 s in response to s...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199807130-00040
更新日期:1998-07-13 00:00:00
abstract::The neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and transported into synaptic vesicles by the vesicular acetylcholine transporter (VAChT). Recently it has been reported that the entire coding region of VAChT mRNA is located in the first intron of the ChAT gene. In this study, ChAT...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199505090-00004
更新日期:1995-05-09 00:00:00
abstract::We have previously shown that hippocampal long-term potentiation (LTP), one form of synaptic plasticity that may underlie learning and memory, is attenuated by blocking neuron activity of the basolateral amygdala (BLA). In the present study we investigated the amygdala noradrenergic or cholinergic contribution to hipp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199709290-00027
更新日期:1997-09-29 00:00:00
abstract::Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833730b7
更新日期:2010-04-21 00:00:00
abstract::Ciliary neurotrophic factor (CNTF), leukaemia inhibitory factor (LIF), oncostatin M (OSM), interleukin-6 (IL-6), and interleukin-11 (IL-11) are structurally and functionally related cytokines. We compared their survival-promoting activities on embryonic chick and newborn rat dorsal root ganglion (DRG) neurones. Human ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1995-12-29 00:00:00
abstract::A bilateral spino-bulbo-spinal circuit conveys information from/to the male urogenital tract and perineal muscles. This is the first electrophysiological report of another descending pathway, one which conveys output from the medullary reticular formation (MRF) to activate postganglionic sympathetic fibers contained w...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200002070-00031
更新日期:2000-02-07 00:00:00
abstract::The present study examined potential neuroprotective effects of HU-211, a synthetic non-psychotropic cannabinoid with non-competitive NMDA antagonist properties on neurones exposed to various excitotoxins in culture. HU-211 was found to protect neurones from NMDA and quisqualate-induced toxicity but not that produced ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199312000-00013
更新日期:1993-12-13 00:00:00
abstract::It is a matter of dispute whether or not recurrent epileptic seizures cause neuronal damage in the human brain. We approached this question by measuring the volumes of the amygdala, hippocampus and parahippocampal gyrus with magnetic resonance imaging in 15 controls, 13 unmedicated patients with newly diagnosed epilep...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199412300-00055
更新日期:1994-12-30 00:00:00
abstract::The terrestrial snail Helix lucorum is a promising model for molecular neurobiology since its central nervous system (CNS) is simple and contains many morphologically and functionally identified large neurones. Among these, the giant interneurones located in pleural and parietal ganglia are especially interesting beca...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199401000-00014
更新日期:1994-01-31 00:00:00
abstract::This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283455c23
更新日期:2011-06-22 00:00:00
abstract::GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000215779.76602.93
更新日期:2006-05-29 00:00:00
abstract::To investigate the phonological influences on the lexicosemantic process with a strong orthographic constraint, we used kanji (morphogram) homophone words and measured, using magnetoencephalography, the neural activities during the silent reading of prime-target pairs. The primes were phonologically the same as or dif...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f16ddf
更新日期:2007-11-19 00:00:00
abstract::In order to assess effects of glucagon-like peptide-1 (GLP-1) in the brain excluding the hypothalamus, the effects of GLP-1 (7-36) amide, a naturally produced active fragment, on the electroencephalogram and hippocampal single unit activities of anesthetized male Wistar rats were examined. I.c.v. injection of GLP-1 (7...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199906030-00004
更新日期:1999-06-03 00:00:00
abstract::A unilateral ibotenic acid lesion of the nucleus basalis magnocellularis in the rat, which is known to produce a reduction in cortical choline acetyltransferase activity and acetylcholine release, produces a decrease of 125I-alpha-bungarotoxin and 125I-kappa-bungarotoxin binding sites in the frontoparietal cortex of t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199104000-00004
更新日期:1991-04-01 00:00:00
abstract::Mammalian TIMELESS (TIM) was identified due to its sequence similarity to Drosophila TIM, an essential circadian clock protein in flies. Published literature is inconsistent regarding the rhythmic expression of mammalian Tim, the interaction of the TIM protein with other clock proteins and its role in regulating clock...
journal_title:Neuroreport
pub_type: 杂志文章,评审
doi:10.1097/01.wnr.0000233092.90160.92
更新日期:2006-08-21 00:00:00
abstract::Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200210070-00015
更新日期:2002-10-07 00:00:00
abstract::The effect of thyroid hormone (TH) deficiency on the expression of neurofilament (NF) proteins and their intracellular distribution has been examined in primary cultures of neurons from embryonic rat cerebra. Northern blot analysis showed that in TH-deficient (THdef) neurons, the expression of all three NF mRNAs (NF-L...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200008210-00022
更新日期:2000-08-21 00:00:00
abstract::We present the first assessment of motion vision in childhood autism. Postural reactivity to visually perceived motion was measured in five autistic children and 12 normal controls of the same chronological age. Anteroposterior as well as total body sway occurring on a force platform in response to movements in the vi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199505300-00034
更新日期:1995-05-30 00:00:00
abstract::The present study was performed to examine how intention to learn and explicit knowledge in sequence learning are reflected in event-related potentials. Participants responded to numerals presented in a repeating order, which were replaced infrequently by deviant numerals. The participants were given incidental or int...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200505120-00010
更新日期:2005-05-12 00:00:00
abstract::Hypoxia or global ischemia causes rapid loss of consciousness and a sudden increase in spontaneous transmitter release suggesting that coordinated synaptic activity is impaired. Gamma oscillations (30-100 Hz) are thought to provide for binding of parallel processed information in the brain, contributing to cognition a...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f13e4f
更新日期:2007-11-19 00:00:00
abstract::Rap1A, first identified as a suppressor of transformed phenotype induced by an activated ras oncogene, is abundantly expressed in the brain. Its neurophysiological function, however, is poorly understood. When an activated Rap1A mutant (Rap1-12V) or a dominant negative H-Ras mutant (Ras-17N) was expressed in CA1 neuro...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200307010-00003
更新日期:2003-07-01 00:00:00
abstract::We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200207190-00006
更新日期:2002-07-19 00:00:00
abstract::Our previous studies have shown that Panax notoginseng saponins (PNS) play a protective role in learning dysfunction of Alzheimer's disease, inhibit the deposition of Aβ1-40 and Aβ1-42, and reduce the content of App in the brain of SAMP8. In this study, we aimed to investigate the effects of PNS on α, β, and γ secreta...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000048
更新日期:2014-01-22 00:00:00
abstract::We aimed to ascertain whether pyrethroid insecticides could influence the vesicular transport of the excitatory amino acid glutamate. The incubation of rat cortical synaptic vesicles with resmethrin and permethrin, consistently stimulated both ATP-dependent and -independent uptake of [3H]glutamate, while not evoking d...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199810260-00034
更新日期:1998-10-26 00:00:00
abstract::The aim of this study was to reveal a potential effect of emotion on cognitive control in the implicit memory task with emotionally neutral and unpleasant words in healthy controls and patients with schizophrenia using a 3.0 T functional MRI (fMRI). A total of 15 patients with schizophrenia and 15 healthy controls und...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000405
更新日期:2015-08-05 00:00:00
abstract::The autoradiographic distribution of Ca(2+)-sensitive high- and low-affinity binding sites for the N-type calcium channel ligand, [125I]omega-conotoxin GVIA, has been examined in rat brain. Both classes of sites were rather evenly distributed, exhibiting their highest density in cell body rich layers, such as the pyra...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199405000-00025
更新日期:1994-05-09 00:00:00
abstract::Short-latency ocular following responses in monkeys, induced by first- and second-order motion during a fixation task, were sensitive to stimulus size, retinal eccentricity and motion duration. Latency of eye movements was no different for first- or second-order motion and simply marked the occurrence of movement in t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199812010-00039
更新日期:1998-12-01 00:00:00
abstract::Previously we found that musicians have significantly larger anterior corpus callosum (CC). In the current study, we intended to replicate and extend our previous results using a new and larger sample of gender-matched subjects (56 right-handed professional musicians and 56 age- and handedness-matched controls). We fo...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200302100-00009
更新日期:2003-02-10 00:00:00
abstract::To test the combined effect of high glucose and decreased Na+/K+-pump activity, a condition which closely mimics the diabetic state, on nerve ionic currents, changes in action potential and membrane current induced by high glucose in the presence of ouabain were investigated using voltage clamp analysis in rat single ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200008030-00040
更新日期:2000-08-03 00:00:00
abstract::Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199509000-00017
更新日期:1995-09-11 00:00:00