Nucleus basalis lesions decrease alpha- and kappa-bungarotoxins binding in rat cortex.

abstract：:Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation of BMMCs is considered a potential approach to promoting the repair of ischemic damaged organs. H...

journal_title：Neuroreport

authors： Takagi T,Yoshida T,Okada M,Hata R,Hato N,Gyo K,Hakuba N

更新日期：2014-08-06 00:00:00

abstract：:The whole-cell patch clamp technique was used to investigate the actions of the opioid agonist U50488H on Ca2+ and K+ currents in differentiated NG108-15 cells. U50488H (5-50 microM) caused a concentration-dependent, reversible inhibition of high voltage-activated Ca2+ currents which persisted in the presence of nifed...

journal_title：Neuroreport

authors： Carpenter E,Gent JP,Peers C

更新日期：1996-07-29 00:00:00

abstract：:Hair cells in the frog semicircular canal, studied by the whole-cell patch-clamp technique, display three distinct Ca2+ currents: two non-inactivating components (L type and R type, the latter termed R2 in the following) and a second R type current (termed R1), which runs down first and inactivates in a Ca2+-dependent...

journal_title：Neuroreport

authors： Rispoli G,Martini M,Rossi ML,Rubbini G,Fesce R

更新日期：2000-08-21 00:00:00

abstract：:Dopamine D2 receptor (D2R) signalling is implicated in limbic seizure propagation and seizure-induced neurodegeneration. D2R-/- mice display increased susceptibility to kainic acid (KA) seizures and seizure-induced apoptosis of hippocampal neurons. Here we further investigated the molecular pathways of KA-induced apop...

journal_title：Neuroreport

authors： Tripathi PP,Santorufo G,Brilli E,Borrelli E,Bozzi Y

更新日期：2010-08-23 00:00:00

abstract：:The developmental time-course of type I and type II benzodiazepine receptors in the chick optic lobe was determined using a triazolopyridazine, CL 218872. At embryonic day 13 most of the binding sites corresponded to type II (98.23%), while type I represented only a minor proportion (1.77%). During development there w...

journal_title：Neuroreport

authors： Gravielle MC,de Plazas SF

更新日期：1995-10-23 00:00:00

abstract：:We investigated the effect of previous musical training on lateralization of language as indexed by the effects of reading aloud on the modulation of motor evoked potentials (MEPs) induced in the first dorsal interosseus muscles (FDI) by transcranial magnetic stimulation (TMS) of the primary motor cortex. We studied 1...

journal_title：Neuroreport

authors： Lin KL,Kobayashi M,Pascual-Leone A

更新日期：2002-05-07 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00

abstract：:We have investigated the hypothesis that the acute ischemic swelling of the radial dendrites connected to the inner hair cells (IHCs) is mediated by glutamatergic receptors. In control cochleas, after 20 min ischemia all the dendrites were dramatically swollen. Conversely, after a perfusion of 50 microM 6-7-dinitroqui...

journal_title：Neuroreport

authors： Pujol R,Puel JL,Eybalin M

更新日期：1992-04-01 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 consumes NAD to catalyze poly(ADP-ribosyl)ation of target proteins, which modulates various biological functions. However, excessive poly(ADP-ribose) polymerase-1 activation mediates oxidative cell death. Our recent studies have indicated that NAD can enter into astrocytes to prevent poly...

journal_title：Neuroreport

authors： Zhu K,Swanson RA,Ying W

更新日期：2005-08-01 00:00:00

abstract：:Intrinsic circuitry in the barrel cortex has been shown to be readily modifiable in response to changes in the patterns of sensory input, even in adult animals. It is believed that sensory experience modifies synaptic circuits by imposing specific patterns of repetitive presynaptic and postsynaptic coactivity, i.e. by...

journal_title：Neuroreport

authors： Aroniadou-Anderjaska V,Keller A

更新日期：1995-11-27 00:00:00

abstract：:Schwann cells at the somatic neuromuscular junction possess adenosine receptors that when activated by the release of endogenous transmitter modulate quantal transmitter release. Recently, purinergic receptors have been shown to exist on Schwann cells of axon varicosities in visceral smooth muscle where they are activ...

journal_title：Neuroreport

authors： Lin YQ,Bennett MR

更新日期：2006-04-03 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:Chronic ethanol (EtOH) exposure can cause intracellular Ca overload by stimulating calcium channel receptors and trigger apoptosis of neurons. NCX3 may play a cytoprotective role in intracellular Ca excretion. In this study, the effect of EtOH on NCX3 was analyzed by observing NCX3 expression in the hippocampus of chr...

journal_title：Neuroreport

authors： Wang C,Wang X,Li Y,Xia Z,Liu Y,Yu H,Xu G,Wu X,Zhao R,Zhang G

更新日期：2019-04-10 00:00:00

abstract：:Mammalian TIMELESS (TIM) was identified due to its sequence similarity to Drosophila TIM, an essential circadian clock protein in flies. Published literature is inconsistent regarding the rhythmic expression of mammalian Tim, the interaction of the TIM protein with other clock proteins and its role in regulating clock...

journal_title：Neuroreport

authors： Gotter AL

更新日期：2006-08-21 00:00:00

abstract：:The current study aimed to investigate the altered cerebellar-cerebral functional connectivity (FC) induced by radiotherapy to nasopharyngeal carcinoma (NPC) patients. Twenty-four NPC patients without treatment, and 35 NPC patients receiving radiotherapy underwent functional MRI scanning. Montreal cognitive assessment...

journal_title：Neuroreport

authors： Ma Q,Zeng LL,Qin J,Luo Z,Su J,Wu D,Qiu S,Hu D

更新日期：2017-08-16 00:00:00

abstract：:The effect of chronic treatment with vitamin E (VE) on acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity, as assessed by striatal dopamine (DA) depletion, was studied. Male C57B1/6J mice were fed VE (48 mg kg-1 per day, intragastric) for 4, 8, or 12 weeks prior to administration of MPTP (...

journal_title：Neuroreport

authors： Gong L,Daigneault EA,Acuff RV,Kostrzewa RM

更新日期：1991-09-01 00:00:00

abstract：:Nerve damage often leads to nervous system dysfunction and neuropathic pain. The serine-threonine kinases receptor-interacting protein 1 (RIP1) and 3 (RIP3) are associated with inflammation and cell necrosis. This study aimed to explore the role of RIP1 and RIP3 in sciatic nerve chronic constriction injury (CCI) in mi...

journal_title：Neuroreport

authors： Pu S,Li S,Xu Y,Wu J,Lv Y,Du D

更新日期：2018-11-07 00:00:00

abstract：:Prolonged activation of brain N-methyl-D-aspartic acid (NMDA) receptors increases intraneuronal (Ca2+) and nitric oxide (NO) synthesis, and may be responsible for neuronal death in acute brain insults and chronic neurodegenerative diseases. NO can be converted in vitro to toxic hydroxyl (OH) radical. Using microdialys...

journal_title：Neuroreport

authors： Hammer B,Parker WD Jr,Bennett JP Jr

更新日期：1993-10-25 00:00:00

abstract：:Functional imaging has struggled for two decades to establish a quantitative link between the neuronal activity and the change in signal obtained. This review proposes a division of neuronal activity into a component relating to the electrical discharge activity and a component relating to the size of the activated ne...

journal_title：Neuroreport

authors： Marcar VL,Loenneker T

更新日期：2004-09-15 00:00:00

abstract：:We investigated the roles of the auditory cortex in discrimination learning of vowel-like sounds consisting of multiple formants. Rats were trained to discriminate between synthetic sounds with four formants. Bilateral electrolytic lesions including the primary auditory cortex and the dorsal auditory association corte...

journal_title：Neuroreport

authors： Kudoh M,Nakayama Y,Hishida R,Shibuki K

更新日期：2006-11-27 00:00:00

abstract：:High concentrations of local anesthetics are neurotoxic, but the mechanism for this neurotoxicity is obscure. Here, we report increased concentrations of glutamate in the cerebrospinal fluid after intrathecal injections of high concentrations of tetracaine (a local anesthetic). The peak concentrations of glutamate aft...

journal_title：Neuroreport

authors： Ohtake K,Matsumoto M,Wakamatsu H,Kawai K,Nakakimura K,Sakabe T

更新日期：2000-04-07 00:00:00

abstract：:We have found that regeneration of the rat sciatic nerve is stimulated if the rats are exposed to a 50 Hz sinusoidal magnetic field. In this study we investigated the effect of a Ca2+ antagonist, methoxyverapamil (D600) on this response. D600 was administered to the regenerating segment of the nerve via implanted osmo...

journal_title：Neuroreport

authors： Rusovan A,Kanje M

更新日期：1992-09-01 00:00:00

abstract：:By using high-resolution, conventional, and neuromelanin-sensitive magnetic resonance imaging techniques, we reviewed the normal anatomy of the nuclei consisting of monoamine neurons such as dopaminergic, noradrenergic, and serotoninergic neurons and noted the changes in these nuclei that occur in some degenerative an...

journal_title：Neuroreport

authors： Sasaki M,Shibata E,Tohyama K,Kudo K,Endoh J,Otsuka K,Sakai A

更新日期：2008-11-19 00:00:00

abstract：:Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation and nerve injury. Recent evidence has also suggested the critical role of an epigenetic mechanism in ...

journal_title：Neuroreport

authors： Li K,Zhao GQ,Li LY,Wu GZ,Cui SS

更新日期：2014-10-01 00:00:00

abstract：:Factors controlling proliferation and differentiation are crucial in advancement of neural cell-based experimental neurodegenerative therapies. In this regard, nicotinamide has been shown to determine the fate of neural cells, enhance neuralization, and influence DNA repair and apoptosis. This study investigated wheth...

journal_title：Neuroreport

authors： Griffin SM,Pickard MR,Orme RP,Hawkins CP,Fricker RA

更新日期：2013-12-18 00:00:00

abstract：:Central sensitization is a fundamental mechanism contributing to acute and chronic pain conditions. Our previous studies have documented a glutamatergic, purinergic and glial-dependent central sensitization that can be induced in rat medullary dorsal horn nociceptive neurons by mustard oil application to the tooth pul...

journal_title：Neuroreport

authors： Chiang CY,Li Z,Dostrovsky JO,Sessle BJ

更新日期：2010-02-17 00:00:00

abstract：:Using NADPH-diaphorase (NADPH-d) staining as a marker for the enzyme nitric oxide synthase (NOS) we investigated the possible sites of nitric oxide (NO) synthesis in the olfactory pathways of an insect brain. Staining of frozen sections revealed NADPH-d activity in neurones and in glial cells. A cluster of intensely s...

journal_title：Neuroreport

authors： Bicker G,Hähnlein I

更新日期：1995-01-26 00:00:00

abstract：:The effect of temporal interference of physiological signals on time-lag effective connectivity, derived from a functional network connectivity tool box (FNC), was examined by a blood-oxygen-level-dependent functional MRI study of action. The known effect of physiological signals on time-lag FNC was verified by (a) co...

journal_title：Neuroreport

authors： Huang JM,Cheng CM,Chou CC,Chen YC,Hsu PY,Yeh TC

更新日期：2013-01-09 00:00:00

abstract：:Net-like structures surrounding several types of neurones contain glycoconjugates which are detectable by lectins specific for N-acetylgalactosamine. Wisteria floribunda agglutinin (WFA) was introduced as a further marker for the visualization of such perineuronal nets, which were also revealed in regions of the rat b...

journal_title：Neuroreport

authors： Härtig W,Brauer K,Brückner G

更新日期：1992-10-01 00:00:00

abstract：:DJ-1, originally identified as an oncogene product, is involved in multiple processes, including cellular transformation, the oxidative stress response, and transcriptional regulation. We had previously found that DJ-1 was closely associated with the proliferation and differentiation of cultured neuronal stem cells. I...

journal_title：Neuroreport

authors： Sun Y,Wang Y,Zhao X,Pu X

更新日期：2018-03-07 00:00:00