NADPH-diaphorase expression in neurones and glial cells of the locust brain.

abstract：:Single unit recordings were made from the ventral posterior lateral thalamus of anaesthetized rats to characterize responses to the activation of new receptive fields induced by either local anaesthesia or amputation. Receptive fields confined to single digits were identified and evoked unit responses to the stimulati...

journal_title：Neuroreport

authors： Shin HC,Park S,Son J,Sohn JH

更新日期：1995-12-29 00:00:00

abstract：:Densities of serotonin transporters (5-HTT) in the postmortem neocortex of behaviorally assessed Alzheimer's disease (AD) patients and aged controls were measured by radioligand binding with [3H]citalopram. It was found that 5-HTT sites in the temporal cortex of AD patients with prominent antemortem anxiety were unalt...

journal_title：Neuroreport

authors： Tsang SW,Lai MK,Francis PT,Wong PT,Spence I,Esiri MM,Keene J,Hope T,Chen CP

更新日期：2003-07-18 00:00:00

abstract：:The effect of huperzine A (HupA) on oxygen-glucose deprivation (OGD)-induced injury was investigated in the rat pheochromocytoma cell line PC12. OGD for 3 h and reoxygenation for 24 h triggered apoptosis characterized by chromatin condensation, nucleus fragmentation and DNA laddering. The temporal profile of c-jun, p5...

journal_title：Neuroreport

authors： Zhou J,Fu Y,Tang XC

更新日期：2001-07-20 00:00:00

abstract：:Diabetes is often associated with impairments in brain functioning. However, the injury of specific functioning areas of the brain is not clear. To address this problem, the present study was designed to investigate possible brain functioning change in specific brain areas, particularly in areas associated with vision...

journal_title：Neuroreport

authors： Wang Z,Lu Z,Li J,Pan C,Jia Z,Chen H,Ge X

更新日期：2017-01-18 00:00:00

abstract：:Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...

journal_title：Neuroreport

authors： Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

更新日期：1997-04-14 00:00:00

abstract：:In a previous event-related fMRI study, we showed that the left occipitotemporal cortex was specifically involved in the abstract categorization of visually presented alphabetic symbols. Here, we duplicate the fMRI study by measuring visual event-related potentials to verify whether the left posterior cortex supports ...

journal_title：Neuroreport

authors： Gros H,Doyon B,Rioual K,Celsis P

更新日期：2002-06-12 00:00:00

abstract：:Huntingtin, the protein product of the Huntington's disease gene, associates with vesicle membranes and microtubules in neurons. Analysis of axonal transport with a stop-flow, double crush ligation approach in rat sciatic nerve showed that full length huntingtin (350 kDa) and an N-terminal cleavage product (50 kD) wer...

journal_title：Neuroreport

authors： Block-Galarza J,Chase KO,Sapp E,Vaughn KT,Vallee RB,DiFiglia M,Aronin N

更新日期：1997-07-07 00:00:00

abstract：:We examined differences in brain activity in response to two types of mechanical stimulation, which have been reported previously as being perceptually indistinguishable but having different impacts on autonomic reflexes. As an indicator of brain activity, glucose metabolism was evaluated by PET with 2-[F]fluoro-2-deo...

journal_title：Neuroreport

authors： Watanabe N,Ishii K,Hotta H,Oda K,Sakata M,Toyohara J,Ishiwata K

更新日期：2013-05-29 00:00:00

abstract：:The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model. In rats the carotid territory was embolized with a single clot formed in a polyethylene tube and washed with saline. Fifteen m...

journal_title：Neuroreport

authors： Overgaard K,Sereghy T,Pedersen H,Boysen G

更新日期：1992-10-01 00:00:00

abstract：:To test for the feature specificity of adaptation of auditory-cortex magnetoencephalographic N1m responses to phonemes during lipreading, we presented eight healthy volunteers with a simplified sine-wave first-formant (F1) transition shared by /ba/, /ga/, and /da/, and a continuum of second-formant (F2) transitions co...

journal_title：Neuroreport

authors： Jääskeläinen IP,Kauramäki J,Tujunen J,Sams M

更新日期：2008-01-08 00:00:00

abstract：:Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...

journal_title：Neuroreport

authors： Orr-Urtreger A,Kedmi M,Rosner S,Karmeli F,Rachmilewitz D

更新日期：2005-07-13 00:00:00

abstract：:We validated and used a high-performance liquid chromatography procedure for the determination of four different amino acid neurotransmitters in cultured rat neurons and used culture medium. Samples were derivatized using 2,4-dinitrofluorobenzene and the amino acids were separated on a C18 column. The method yielded g...

journal_title：Neuroreport

authors： Zhang F,Ma XL,Wang YX,Su RR,He C,Tian K,Liu YQ

更新日期：2016-05-04 00:00:00

abstract：:Capsaicin in the adult animal causes antinociception due to the massive release of neurotransmitters, including substance P (SP), from primary afferent C-fibers. The results of the present study indicate that capsaicin-induced antinociception in the adult is sensitive to inhibition by dizocilpine (MK-801). The failure...

journal_title：Neuroreport

authors： Sun X,Larson AA

更新日期：1993-09-03 00:00:00

abstract：:The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

journal_title：Neuroreport

authors： Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

更新日期：1996-04-10 00:00:00

abstract：:We previously reported that the methanol extract of Ashwagandha (roots of Dunal) induced dendrite extension in a human neuroblastoma cell line. In this study, we found that six of the 18 compounds isolated from the methanol extract enhanced neurite outgrowth in human neuroblastoma SH-SY5Y cells. Double immunostaining ...

journal_title：Neuroreport

authors： Kuboyama T,Tohda C,Zhao J,Nakamura N,Hattori M,Komatsu K

更新日期：2002-10-07 00:00:00

abstract：:Maintenance of long-term potentiation in perforant path-granule cell synapses is accompanied by increased glutamate release. Here we investigate the role of synaptophysin in release and in expression of long-term potentiation in dentate gyrus. We report that long-term potentiation was accompanied by increased endogeno...

journal_title：Neuroreport

authors： Mullany PM,Lynch MA

更新日期：1998-08-03 00:00:00

abstract：:Multiple signal classification is an alternative to the traditional dipole fitting source analysis methods. Our aim was to assess the clinical usefulness of this algorithm and to compare the localization of the epileptiform electroencephalography discharges with the regions of altered cerebral blood flow in 10 patient...

journal_title：Neuroreport

authors： Beniczky S,Oturai PS,Alving J,Sabers A,Herning M,Fabricius M

更新日期：2006-08-21 00:00:00

abstract：:The 29 amino acid neuropeptide galanin is normally expressed in < 5% of sensory neurons in the adult dorsal root ganglia. After nerve transection (axotomy), the galanin content of the dorsal root ganglia rises 120-fold and the peptide is then expressed in > 50% of neurons. Published data suggest that galanin plays a r...

journal_title：Neuroreport

authors： Bacon A,Holmes FE,Small CJ,Ghatei M,Mahoney S,Bloom S,Wynick D

更新日期：2002-11-15 00:00:00

abstract：:The effect of centrally administered bombesin on core temperature was investigated in rats which had been chronically fitted with a cannula in the third cerebral ventricle and with an intraperitoneal temperature-monitoring radiotransmitter. Intracerebroventricularly administered bombesin (0.01, 0.1 or 1 microgram) res...

journal_title：Neuroreport

authors： Persaud RA,Coen CW

更新日期：1994-03-21 00:00:00

abstract：:Presenilin-1 (PS-1) and amyloid precursor protein (APP) have been linked to the pathogenesis of Alzheimer's disease. While APP accumulation is well documented in several models of brain injury, the role of PS-1 levels in neurodegeneration, if any, remains to be elucidated. The current studies examined PS-1 and APP exp...

journal_title：Neuroreport

authors： Calingasan NY,Gandy SE,Gibson GE

更新日期：1997-07-28 00:00:00

abstract：:Motor fluctuations that ultimately complicate the response of most parkinsonian patients to levodopa therapy might represent a form of behavioral or neuronal plasticity. Since various forms of neuronal plasticity appear to be mediated by glutamate transmission through the N-methyl-D-aspartate (NMDA) receptor, the effe...

journal_title：Neuroreport

authors： Engber TM,Papa SM,Boldry RC,Chase TN

更新日期：1994-12-20 00:00:00

abstract：:(-)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenolic extract in green tea and it has attracted increasing attention for its multiple bioactive effects. However, the mechanisms by which EGCG exerts its neuroprotective actions in Alzheimer's disease (AD) are presently lacking. In the present study, a ...

journal_title：Neuroreport

authors： Guo Y,Zhao Y,Nan Y,Wang X,Chen Y,Wang S

更新日期：2017-07-05 00:00:00

abstract：:This study aimed to examine the spontaneous hemodynamic fluctuations and the dysfunctional brain regions in patients with generalized anxiety disorder (GAD) using resting-state functional MRI. Previous studies have demonstrated some neural networks that are different in this patient group compared with healthy control...

journal_title：Neuroreport

authors： Li C,Su S,Wu H,Zhu Y

更新日期：2018-03-21 00:00:00

abstract：:This study used electroencephalogram measurements to investigate the effects of aging on oscillatory theta modulation during an audiovisual discrimination task. By a wavelet-based time-frequency analysis, age-related theta oscillation response differences were observed within a relatively restricted time range (0-500 ...

journal_title：Neuroreport

authors： Yan T,Bi X,Zhang M,Wang W,Yao Z,Yang W,Wu J

更新日期：2016-08-03 00:00:00

abstract：:Auditory sensory memory is assumed to play an important role in cognitive development, but little is known about it in young children. The aim of this study was to estimate the duration of auditory sensory memory in 2-year-old children. We recorded the mismatch negativity in response to tone stimuli presented with dif...

journal_title：Neuroreport

authors： Glass E,Sachse S,von Suchodoletz W

更新日期：2008-03-26 00:00:00

abstract：:We earlier showed that leucine-rich glioma inactivated 3 (LGI3) colocalizes with amyloid beta peptide (Abeta) taken up by astrocytes both in vitro and in vivo, and that LGI3 accumulated with endocytosis-associated proteins in aged monkey brains. In this study, we confirmed that LGI3 localizes to the endocytic pathway ...

journal_title：Neuroreport

authors： Okabayashi S,Kimura N

更新日期：2008-08-06 00:00:00

abstract：:We examined the effect of a nonphotic stimulus (running in a novel wheel) on the induction of Fos-related proteins in the two well-established neural components of the circadian clock: the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) of the lateral geniculate complex. There was no induction of F...

journal_title：Neuroreport

authors： Janik D,Mrosovsky N

更新日期：1992-07-01 00:00:00

abstract：:Using immunohistochemistry, we investigated in the cat the effects of MPTP, a Parkinsonian syndrome-inducing substance, on brain type B monoamine oxidase (MAO-B) which is responsible for the conversion of MPTP to its neurotoxic product (MPP+). Intraperitoneal administration of MPTP (5 mg kg-1 daily for 5 days) caused ...

journal_title：Neuroreport

authors： Lin JS,Hou Y,Kitahama K,Jouvet M

更新日期：1995-01-26 00:00:00

abstract：:Brain membrane phospholipid fatty acid composition is investigated in Alzheimer's disease using fresh pathologically proven autopsy material. The most striking abnormalities in Alzheimer brains compared to age-matched controls are found in the n - 6 line of polyunsaturated fatty acids (PUFA) showing an elevation of 18...

journal_title：Neuroreport

authors： Nakada T,Kwee IL,Ellis WG

更新日期：1990-10-01 00:00:00

abstract：:Transcription factors have been used as neuronal markers in the nucleus accumbens (ACB) of male juvenile spontaneously hypertensive rats (SHR), an animal model of attention-deficit hyperactivity disorder (ADHD), to trace putative neural substrates. In SHR, immunocytochemistry and PC-assisted image analysis showed lowe...

journal_title：Neuroreport

authors： Papa M,Sergeant JA,Sadile AG

更新日期：1997-05-06 00:00:00