Abstract:
:We examined the effect of a nonphotic stimulus (running in a novel wheel) on the induction of Fos-related proteins in the two well-established neural components of the circadian clock: the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) of the lateral geniculate complex. There was no induction of Fos immunoreactivity (IR) in the SCN, but the IGL showed distinct Fos IR in animals whose running levels were associated with maximal rhythm shifts. Induction of Fos immunoreactivity was greatest at circadian phases when wheel running induces phase shifts. This temporal and spatial specificity of Fos induction is evidence that the intergeniculate leaflet mediates nonphotic signals to the circadian clock.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Janik D,Mrosovsky Ndoi
10.1097/00001756-199207000-00007subject
Has Abstractpub_date
1992-07-01 00:00:00pages
575-8issue
7eissn
0959-4965issn
1473-558Xjournal_volume
3pub_type
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