SNAP-25 is the major immunoreactive component of the brain-specific D3 protein.

abstract：:In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....

journal_title：Neuroreport

authors： Le Van Quyen M,Martinerie J,Baulac M,Varela F

更新日期：1999-07-13 00:00:00

abstract：:Transient global amnesia (TGA), characterised by a profound anterograde amnesia, is a model of interest to study the acquisition of novel meanings independent of episodic functioning. Three patients were tested during a TGA attack, two in the early recovery phase and the third during the acute phase of TGA, with a sem...

journal_title：Neuroreport

authors： Guillery B,Desgranges B,Katis S,de la Sayette V,Viader F,Eustache F

更新日期：2001-12-04 00:00:00

abstract：:Recently, it has been shown that visual perception can be radically altered by signals of other modalities. For example, when a single flash is accompanied by multiple auditory beeps, it is often perceived as multiple flashes. This effect is known as the sound-induced flash illusion. In order to investigate the princi...

journal_title：Neuroreport

authors： Shams L,Ma WJ,Beierholm U

更新日期：2005-11-28 00:00:00

abstract：:Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the alpha-synuclein gene were linked to familial Parkinson's Disease (PD). We decided to investigate if these and any other mutations in exons 3 and 4 of the alpha-synuclein gene could be detect...

journal_title：Neuroreport

authors： El-Agnaf OM,Curran MD,Wallace A,Middleton D,Murgatroyd C,Curtis A,Perry R,Jaros E

更新日期：1998-12-01 00:00:00

abstract：:Previous literature shows that feature binding processes elicit fronto-hippocampal areas. The time course of this process, however, remains unknown. This is the first study that investigates feature binding using magnetoencephalography. Synthetic aperture magnetometry analysis was used to localize sources of increased...

journal_title：Neuroreport

authors： Filbey FM,Holroyd T,Carver F,Sunderland T,Cohen RM

更新日期：2005-11-07 00:00:00

abstract：:SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...

journal_title：Neuroreport

authors： Fang ZX,Hong SQ,Li TS,Wang J,Xie LL,Han W,Jiang L

更新日期：2019-06-12 00:00:00

abstract：:Effects of glutamate on synaptic transmission in the submucosal plexus of guinea-pig small intestine were studied with intracellular electrophysiological recording methods. Glutamate suppressed stimulus-evoked slow excitatory postsynaptic potentials (EPSPs) and increased the amplitude of slow inhibitory postsynaptic p...

journal_title：Neuroreport

authors： Ren J,Hu HZ,Liu S,Xia Y,Wood JD

更新日期：1999-09-29 00:00:00

abstract：:Recent studies have yielded contradictory evidence on whether visual speech perception (watching articulatory gestures) can activate the human primary auditory cortex. To circumvent confounds due to inter-individual anatomical variation, we defined our subjects' Heschl's gyri and assessed blood oxygenation-dependent s...

journal_title：Neuroreport

authors： Pekkola J,Ojanen V,Autti T,Jääskeläinen IP,Möttönen R,Tarkiainen A,Sams M

更新日期：2005-02-08 00:00:00

abstract：:In the anaesthetized rat, low frequency electrical stimulation of the Zusanli acupoint (S36) or noxious thermal stimulation caused by immersing the footpad in water at 52 degrees C caused marked expression of c-fos in the anterior lobe of the pituitary gland, as well as in the arcuate and some nearby hypothalamic nucl...

journal_title：Neuroreport

authors： Pan B,Castro-Lopes JM,Coimbra A

更新日期：1994-08-15 00:00:00

abstract：:Experience affects how brains respond to sound. Here, we examined how the sensitivity and selectivity of auditory cortical neuronal responses were affected in adult rats by the repeated presentation of a complex sound that was paired with basal forebrain stimulation. The auditory cortical region that was responsive to...

journal_title：Neuroreport

authors： Mercado E,Bao S,Orduña I,Gluck MA,Merzenich MM

更新日期：2001-07-20 00:00:00

abstract：:We earlier showed that leucine-rich glioma inactivated 3 (LGI3) colocalizes with amyloid beta peptide (Abeta) taken up by astrocytes both in vitro and in vivo, and that LGI3 accumulated with endocytosis-associated proteins in aged monkey brains. In this study, we confirmed that LGI3 localizes to the endocytic pathway ...

journal_title：Neuroreport

authors： Okabayashi S,Kimura N

更新日期：2008-08-06 00:00:00

abstract：:The amounts of three adenylyl cyclase (AC) subtypes in membranes from brain obtained post-mortem from patients with dementia of Alzheimer type (DAT) and controls were studied by Western blotting using polyclonal antibodies. AC subtypes were characterized by preabsorption by complementary peptides, species difference, ...

journal_title：Neuroreport

authors： Yamamoto M,Ozawa H,Saito T,Frölich L,Riederer P,Takahata N

更新日期：1996-11-25 00:00:00

abstract：:While effects of attention on late and middle latency components of the evoked potential have been demonstrated, similar effects on brain stem evoked potentials--in particular on the human frequency-following potential (FFP)--are controversial. The FFP is a response to tone bursts in the frequency range of human langu...

journal_title：Neuroreport

authors： Hoormann J,Falkenstein M,Hohnsbein J

更新日期：1994-08-15 00:00:00

abstract：:We previously reported that clusterin enhances astrocyte proliferation and extracellular signal-regulated kinase (ERK) activity. It, however, remains largely unknown how clusterin promotes cell growth. Here, we investigate the signaling pathway and related molecules underlying astrocyte proliferation by clusterin. Exo...

journal_title：Neuroreport

authors： Shim YJ,Shin YJ,Jeong SY,Kang SW,Kim BM,Park IS,Min BH

更新日期：2009-03-04 00:00:00

abstract：:Acute mitochondrial dysfunction in the cochlea is likely to result in hearing loss as a consequence of local energy shortage, similar to ischemia- or noise-induced hearing loss. To establish an animal model of acute cochlear mitochondrial dysfunction, we applied a mitochondrial toxin, 3-nitropropionic acid (3-NP) in t...

journal_title：Neuroreport

authors： Hoya N,Okamoto Y,Kamiya K,Fujii M,Matsunaga T

更新日期：2004-07-19 00:00:00

abstract：:Peripheral nerve injury therapy in the clinic remains less than satisfactory. The gold standard of treatment for long peripheral nerve defects is autologous nerve grafts; however, numerous clinical complications are associated with this treatment. As tissue engineering has developed, tissue-engineered nerve grafts (TE...

journal_title：Neuroreport

authors： Yan L,Yao Z,Lin T,Zhu Q,Qi J,Gu L,Fang J,Zhou X,Liu X

更新日期：2017-10-18 00:00:00

abstract：:Hydrogen peroxide (H₂O₂) is a ubiquitous reactive oxygen species that can induce several inner ear disorders. In this study, we recorded the potassium (K) currents in acutely isolated inner hair cells of guinea pig cochlea, and investigated the effects of H₂O₂. We also observed the morphological changes in inner hair ...

journal_title：Neuroreport

authors： Kimitsuki T,Komune N,Noda T,Takaiwa K,Ohashi M,Komune S

更新日期：2010-11-17 00:00:00

abstract：:Slices of hippocampus were incubated with Arg-Gly-Asp (RGD) peptides known to block members of the integrin class of matrix receptors. Though the peptides caused no detectable difference in the amount of long-term potentiation (LTP) expressed in the CA1 field 1-2 min after induction with high frequency stimulation, th...

journal_title：Neuroreport

authors： Xiao P,Bahr BA,Staubli U,Vanderklish PW,Lynch G

更新日期：1991-08-01 00:00:00

abstract：:This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...

journal_title：Neuroreport

authors： Matsumoto M,Nakagawa T,Higashi T,Kim TS,Kojima K,Kita T,Sakamoto T,Ito J

更新日期：2005-05-31 00:00:00

abstract：:The distribution of histamine H1, H3, dopamine D1 and D2 receptors in the brain was studied by receptor autoradiography using a high-sensitivity and high-resolution imaging plate system. [3H]Pyrilamine, [3H](R)alpha-methyl-histamine, [11C]SCH23390, and [11C]N-methylspiperone (or [11C]YM-09151-2) were used as ligands t...

journal_title：Neuroreport

authors： Yanai K,Ryu JH,Watanabe T,Iwata R,Ido T

更新日期：1992-11-01 00:00:00

abstract：:The cochlea can be protected from acoustic trauma by moderate-level sound exposure. It is suggested that olivocochlear system may play a significant role in this protection. This study was performed to investigate distortion product otoacoustic emission (DPOAE) amplitudes changes and the efficiency of contralateral no...

journal_title：Neuroreport

authors： Peng JH,Tao ZZ,Huang ZW

更新日期：2007-07-16 00:00:00

abstract：:Brief tetanic stimulation of parallel fibres can evoke a slow excitatory postsynaptic potential (EPSP) in cerebellar Purkinje cells that is mediated by metabotropic glutamate receptors (mGluRs). It is likely that the receptor subtype involved is mGluR1, which couples to the production of diacylglycerol and inositol-1,...

journal_title：Neuroreport

authors： Batchelor AM,Vranesic I,Del Principe F,Garthwaite J,Knöpfel T

更新日期：1996-08-12 00:00:00

abstract：:We conducted semiautomated, atlas-based analyses of regional brain volume changes on MRIs of children and adolescents with Down syndrome (DS) (N=15), DS with comorbid autism spectrum disorder (ASD) (N=15), and age-matched or sex-matched typically developing controls (N=22). Selective volumetric changes were correlated...

journal_title：Neuroreport

authors： Carter JC,Capone GT,Kaufmann WE

更新日期：2008-04-16 00:00:00

abstract：:We examined the effect of a nonphotic stimulus (running in a novel wheel) on the induction of Fos-related proteins in the two well-established neural components of the circadian clock: the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) of the lateral geniculate complex. There was no induction of F...

journal_title：Neuroreport

authors： Janik D,Mrosovsky N

更新日期：1992-07-01 00:00:00

abstract：:Ascorbate and glutathione (GSH) are the primary water-soluble antioxidants in the CNS. Oxidative stress, sometimes indicated by loss of these antioxidants, has been linked to several clinical and experimental conditions, including cerebral ischemia. These conditions are also gender-linked, with greater incidence or se...

journal_title：Neuroreport

authors： Ferris DC,Kume-Kick J,Russo-Menna I,Rice ME

更新日期：1995-07-31 00:00:00

abstract：:When we look at our spatial environment we have the feeling that the whole visual field is coloured, yet the density of cone photoreceptors decreases considerably as eccentricity increases. We investigated colour perception (coloured/noncoloured), colour naming and whether colour helps object recognition at eccentrici...

journal_title：Neuroreport

authors： Naïli F,Despretz P,Boucart M

更新日期：2006-10-23 00:00:00

abstract：:The ATP-gated cation channel P2X3 is expressed selectively by rat sensory neurones, and may play a role in nociception by binding ATP released from damaged or inflamed tissues. However, the distribution of this channel in human sensory neurons is not known. Using a specific antibody, we have demonstrated intense P2X3 ...

journal_title：Neuroreport

authors： Yiangou Y,Facer P,Birch R,Sangameswaran L,Eglen R,Anand P

更新日期：2000-04-07 00:00:00

abstract：:In Xenopus oocytes coinjected with poly(A)+ RNA derived from the rat cerebellum and cRNAs for the cloned G protein-gated inwardly rectifying K+ channel (GIRK), GIRK1 and GIRK2, the GABA-B agonist baclofen elicited inwardly rectifying K+ currents. The inward K+ currents elicited by baclofen were inhibited by the select...

journal_title：Neuroreport

authors： Uezono Y,Akihara M,Kaibara M,Kawano C,Shibuya I,Ueda Y,Yanagihara N,Toyohira Y,Yamashita H,Taniyama K,Izumi F

更新日期：1998-03-09 00:00:00

abstract：:We used whole-cell recording to identify, for the first time, GABAergic tonic current in subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of the gamma-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49 of 73 substantia gelatinosa neurons. Thes...

journal_title：Neuroreport

authors： Takahashi A,Mashimo T,Uchida I

更新日期：2006-08-21 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity reproduces many of the features of Parkinson's disease (PD). alpha-Synuclein has been identified as a prominent component of the Lewy body (LB), the pathological hallmark of PD. MPTP-treated primates have been reported to develop intraneuronal inclusion...

journal_title：Neuroreport

authors： Kowall NW,Hantraye P,Brouillet E,Beal MF,McKee AC,Ferrante RJ

更新日期：2000-01-17 00:00:00