Fast transport and retrograde movement of huntingtin and HAP 1 in axons.

abstract：:The effects of interleukin-1beta in the paraventricular nucleus or caudal arcuate nucleus on hypertensive and tachycardiac responses induced by excitation of the central amygdaloid nucleus were studied. We observed that microinjection of sodium glutamate into central amygdaloid nucleus resulted in hypertension and tac...

journal_title：Neuroreport

authors： Lu Y,Chen W,Zou CJ

更新日期：2002-03-25 00:00:00

abstract：:We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...

journal_title：Neuroreport

authors： Friederici AD,Friedrich M,Weber C

更新日期：2002-07-19 00:00:00

abstract：:The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

journal_title：Neuroreport

authors： Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

更新日期：1996-04-10 00:00:00

abstract：:Microinjection of neuropeptide Y (NPY) into the paraventricular nucleus (PVN) of the hypothalamus stimulates eating and increases respiratory quotient. In contrast, administration of opioid receptor antagonists reduces food intake and suppresses NPY-induced feeding. The present study examined whether naloxone methiodi...

journal_title：Neuroreport

authors： Currie PJ,Coscina DV,Moretti J,Avellino MD

更新日期：2000-03-20 00:00:00

abstract：:This study was undertaken to establish a method for the culture of organotypic spinal cord slices. A long-term organotypic spinal cord slice culture was conducted from postnatal rats. Lumbar spinal cord was isolated, and meninges were removed from the spinal cord. The spinal cord was embedded in 4% agarose, and was se...

journal_title：Neuroreport

authors： Liu JJ,Huang YJ,Xiang L,Zhao F,Huang SL

更新日期：2017-11-08 00:00:00

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:Neural imaging studies have shown that the brains of skilled musicians respond differently to musical stimuli than do the brains of non-musicians, particularly for musicians who commenced practice at an early age. Whether brain attributes related to musical skill are attributable to musical practice or are hereditary ...

journal_title：Neuroreport

authors： Pantev C,Roberts LE,Schulz M,Engelien A,Ross B

更新日期：2001-01-22 00:00:00

abstract：:We used an electrophysiological marker of linguistic discordance, the N400 wave, to investigate how linguistic and pseudo-linguistic stimuli are categorised during sleep as compared to waking. During wakefulness, signs of discordance detection were, as expected, greater for pseudo-words than for real but semantically ...

journal_title：Neuroreport

authors： Perrin F,Bastuji H,Garcia-Larrea L

更新日期：2002-07-19 00:00:00

abstract：:We examined the protective effects of N-acetylcysteine (NAC) on the death of glia-free neurons in culture. Under normoxic conditions, the protection by NAC was observed only in cystine-free but not complete medium. When the cells were cultured under hypoxic conditions, NAC much elongated their survival even in the pre...

journal_title：Neuroreport

authors： Sagara J,Bannai S,Shikano N,Makino N

更新日期：2010-04-21 00:00:00

abstract：:Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...

journal_title：Neuroreport

authors： Wang H,Wang X,Scheich H

更新日期：1996-01-31 00:00:00

abstract：:Experiments using chimeric stimuli have shown that the right hemisphere is more influential in processing facial information. Here, again, we found clear evidence that study participants used the information from the left side of the face to inform their gender decisions when chimeric male/female, female/male stimuli ...

journal_title：Neuroreport

authors： Butler SH,Harvey M

更新日期：2005-12-19 00:00:00

abstract：:Using quantitative autoradiography, the present study examined ionotropic glutamatergic receptor binding sites using [3H]dizocilpine, [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate, and [3H]kainate in the posterior cingulate cortex of schizophrenia patients and matched controls. We found a significant increa...

journal_title：Neuroreport

authors： Newell KA,Zavitsanou K,Huang XF

更新日期：2005-08-22 00:00:00

abstract：:Olfactory cues can elicit intense emotional responses. This study used fMRI in male common marmoset monkeys to identify brain areas associated with sexual arousal in response to odors of ovulating female monkeys. Under light anesthesia, monkeys were secured in a specially designed restrainer and positioned in a 9.4 T ...

journal_title：Neuroreport

authors： Ferris CF,Snowdon CT,King JA,Duong TQ,Ziegler TE,Ugurbil K,Ludwig R,Schultz-Darken NJ,Wu Z,Olson DP,Sullivan JM Jr,Tannenbaum PL,Vaughan JT

更新日期：2001-07-20 00:00:00

abstract：:We compared various measures of visual-vestibular interaction in subjects with insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM), as well as non-diabetic controls. Subjects with IDDM exhibited significantly greater postural sway than controls on those conditions in the Clini...

journal_title：Neuroreport

authors： Darlington CL,Erasmus J,Nicholson M,King J,Smith PF

更新日期：2000-02-28 00:00:00

abstract：:Three forms of non-injurious ischemic preconditioning were tested for their effects on endogenous antioxidant activity and subsequent ischemic injury. Test ischemia alone, consisting of 1 h occlusion of both carotid arteries (BCAs) and one middle cerebral artery (MCA), elicited an average volume of cerebral infarction...

journal_title：Neuroreport

authors： Toyoda T,Kassell NF,Lee KS

更新日期：1997-03-03 00:00:00

abstract：:Hypoxic-ischemic brain damage (HIBD) occurs due to intrauterine hypoxia ischemia influencing the energy supply for fetal brain cells, which affects the metabolism of the brain to make the brain suffer a severe damage. Erythropoietin (EPO), which regulates hemacytopoiesis, is a kind of cytokine. EPO is sensitive to hyp...

journal_title：Neuroreport

authors： Huang R,Zhang J,Ren C,Zhang X,Gu L,Dong Y,Zhang J,Zhang J

更新日期：2019-03-06 00:00:00

abstract：:As early-onset hypothyroidism produces audiogenic seizure susceptibility (AGS) in rodents, the role of TR alpha 1 and TR beta thyroid hormone receptors in AGS was investigated. AGS occurs in mice lacking specifically TR beta (Thrb(tm1/tm1)) and is marked by early onset and persistence, thereby differing from mouse str...

journal_title：Neuroreport

authors： Ng L,Pedraza PE,Faris JS,Vennström B,Curran T,Morreale de Escobar G,Forrest D

更新日期：2001-08-08 00:00:00

abstract：:Investigating activity-dependent plasticity in the auditory brain stem of the adult rat, we observed that electrical intracochlear stimulation led to a tonotopically localized modulation of the phosphorylation of the cAMP response element binding protein (CREB) and an equally localized expression of the immediate earl...

journal_title：Neuroreport

authors： Illing RB,Michler SA

更新日期：2001-03-26 00:00:00

abstract：:Methamphetamine (METH) is a drug of abuse used for its stimulant effects. Its neurotoxicity is very variable, and is increased by a number of factors, including crowded conditions and increased ambient temperature. The effects of such factors are increasingly important, with the widespread use of these stimulants at n...

journal_title：Neuroreport

authors： Morton AJ,Hickey MA,Dean LC

更新日期：2001-10-29 00:00:00

abstract：:In a previous event-related fMRI study, we showed that the left occipitotemporal cortex was specifically involved in the abstract categorization of visually presented alphabetic symbols. Here, we duplicate the fMRI study by measuring visual event-related potentials to verify whether the left posterior cortex supports ...

journal_title：Neuroreport

authors： Gros H,Doyon B,Rioual K,Celsis P

更新日期：2002-06-12 00:00:00

abstract：:In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...

journal_title：Neuroreport

authors： Lazic SE,Grote H,Armstrong RJ,Blakemore C,Hannan AJ,van Dellen A,Barker RA

更新日期：2004-04-09 00:00:00

abstract：:GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...

journal_title：Neuroreport

authors： Jackson VR,Nothacker HP,Civelli O

更新日期：2006-05-29 00:00:00

abstract：:We previously reported that clusterin enhances astrocyte proliferation and extracellular signal-regulated kinase (ERK) activity. It, however, remains largely unknown how clusterin promotes cell growth. Here, we investigate the signaling pathway and related molecules underlying astrocyte proliferation by clusterin. Exo...

journal_title：Neuroreport

authors： Shim YJ,Shin YJ,Jeong SY,Kang SW,Kim BM,Park IS,Min BH

更新日期：2009-03-04 00:00:00

abstract：:A fundamental issue in neuronal and glial cells is how intracellular rises in Ca2+ are coupled to signaling cascades and changes in subcellular morphology. We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS. Here, we demonstrate the pr...

journal_title：Neuroreport

authors： Clemen CS,Herr C,Lie AA,Noegel AA,Schröder R

更新日期：2001-05-08 00:00:00

abstract：:Evidences in the central nervous system are in favor that adenosine under basal conditions is released by a direct excitation-secretion modality. However, till now, there is no direct evidence that adenosine is contained in synaptic vesicles. Eight synaptic vesicle fractions were recovered on a discontinuous sucrose g...

journal_title：Neuroreport

authors： Corti F,Cellai L,Melani A,Donati C,Bruni P,Pedata F

更新日期：2013-12-04 00:00:00

abstract：:We have developed in new-born mice a ventral tilted-horizontal slice preparation for pontine stimulation and recording of spontaneous respiratory-like rhythmic trains of glutamatergic excitatory postsynaptic potentials (EPSPs) in medullary neurons. Electrical stimulations (10-50 Hz for 100-500 ms) of the caudal pontin...

journal_title：Neuroreport

authors： Borday V,Kato F,Champagnat J

更新日期：1997-12-01 00:00:00

abstract：:Deficits in processing of auditory stimuli are known to play an important role in the aetiology of dyslexia. To specify the auditory deficit in children at risk for dyslexia, 19 children with a phonological deficit and 15 controls were tested using the mismatch negativity event-related potential, which reflects preatt...

journal_title：Neuroreport

authors： Bitz U,Gust K,Spitzer M,Kiefer M

更新日期：2007-06-11 00:00:00

abstract：:To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

journal_title：Neuroreport

authors： Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

更新日期：2013-09-11 00:00:00

abstract：:While dopamine mechanisms play a crucial role in cocaine-taking behavior, the contribution of endogenous opioid systems is less clear. We assessed the effects of opioid receptor blockade by naloxone (1 mg/kg, s.c.) on the daily performance and subsequent initiation of cocaine self-administration in trained rats. Nalox...

journal_title：Neuroreport

authors： Kiyatkin EA,Brown PL

更新日期：2003-02-10 00:00:00

abstract：:Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...

journal_title：Neuroreport

authors： Tani M,Onimaru H,Ikeda K,Kawakami K,Homma I

更新日期：2010-12-08 00:00:00