Paraventricular nucleus injections of naloxone methiodide inhibit NPY's effects on energy substrate utilization.

abstract：:The in-vivo extracellular release of acetylcholine (ACh) from the striatum of rats was measured by intracerebral microdialysis. The ACh levels were first estimated under normoxic conditions, after which the rats were exposed to either 10% or 5% oxygen for 1 h. The average ACh content was 2.9 pmol/20 min. During hypoxi...

journal_title：Neuroreport

authors： Chleide E,Ishikawa K

更新日期：1990-11-01 00:00:00

abstract：:Upon perfusion with Mg2+-free artificial cerebrospinal fluid (ACSF) organotypic hippocampal slice cultures develop seizure-like events and tonic recurrent discharges in which areas CA3 and CA1 and, in contrast to acute slices, also the dentate gyrus (DG) participate. Using the fluorescent dye propidium iodide (PI) we ...

journal_title：Neuroreport

authors： Kovács R,Gutiérrez R,Kivi A,Schuchmann S,Gabriel S,Heinemann U

更新日期：1999-02-05 00:00:00

abstract：:It is often claimed that binding information across sensory modalities leads to coherent, unitary mental representations. The dramatic illusions experienced as a result of intersensory conflict, such as the McGurk effect, are often attributed to a propensity of the perceptual system to impose multisensory coherence on...

journal_title：Neuroreport

authors： Soto-Faraco S,Alsius A

更新日期：2007-03-05 00:00:00

abstract：:The current study investigated whether an ipsilesional bias in line bisection, a conventional measure for diagnosing hemispatial neglect, persists even in the absence of this syndrome in patients with chronic lesions restricted to posterior association cortex or dorsolateral prefrontal cortex. Both left and right hemi...

journal_title：Neuroreport

authors： Machado L,Rafal RD

更新日期：1999-10-19 00:00:00

abstract：:Five patients with left visual neglect after right hemisphere lesions were examined with a line bisection and a reading task under five different conditions: head and trunk straight ahead, head or trunk oriented 20 degrees to the left and head or trunk oriented 20 degrees to the right. Fixation was always straight ahe...

journal_title：Neuroreport

authors： Schindler I,Kerkhoff G

更新日期：1997-08-18 00:00:00

abstract：:The purpose of this study was to determine whether the system that underlies the mismatch negativity (MMN) of event-related potentials would operate on the basis of objects if stimuli were delivered in such a way as to create the impression of two objects. To this end, tones were alternated between ears with one combi...

journal_title：Neuroreport

authors： Ritter W,Sussman E,Molholm S

更新日期：2000-01-17 00:00:00

abstract：:A previous investigation has suggested that the hyperpolarization-activated cation current Ih does not contribute to the spontaneous firing of midbrain dopaminergic neurons. This conclusion was reached using Cs(-1). We have re-examined this question with extracellular recordings in slices using the more specific block...

journal_title：Neuroreport

authors： Seutin V,Massotte L,Renette MF,Dresse A

更新日期：2001-02-12 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00

abstract：:The autoradiographic distribution of Ca(2+)-sensitive high- and low-affinity binding sites for the N-type calcium channel ligand, [125I]omega-conotoxin GVIA, has been examined in rat brain. Both classes of sites were rather evenly distributed, exhibiting their highest density in cell body rich layers, such as the pyra...

journal_title：Neuroreport

authors： Vandaele SF,Reader TA

更新日期：1994-05-09 00:00:00

abstract：:N- and C-terminal substance P (SP) fragments increase striatal dopamine outflow at nanomolar concentrations. This contrasts with their low affinity for NK1 receptors. To explore this discrepancy, we investigated the interaction of SP and SP fragments with NK1 sites in fresh striatal slices, the same model used in the ...

journal_title：Neuroreport

authors： Michael-Titus AT,Blackburn D,Connolly Y,Priestley JV,Whelpton R

更新日期：1999-07-13 00:00:00

abstract：:The role of dopamine D1A receptors in mediating amphetamine-induced sensitization was investigated using the D1A-deficient mouse. During the drug pre-exposure phase, D1A-deficient and control mice were injected for five consecutive days with saline or amphetamine (2 mg/kg, i.p.). Locomotor activity was measured on the...

journal_title：Neuroreport

authors： Crawford CA,Drago J,Watson JB,Levine MS

更新日期：1997-07-28 00:00:00

abstract：:Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

journal_title：Neuroreport

authors： Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

更新日期：2001-06-13 00:00:00

abstract：:Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...

journal_title：Neuroreport

authors： Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

更新日期：1997-04-14 00:00:00

abstract：:Functional brain imaging techniques hold many promises as the methods of choice for identifying areas involved in the execution of language functions. The success of any of these techniques in fulfilling this goal depends upon their ability to produce maps of activated areas that overlap with those obtained through st...

journal_title：Neuroreport

authors： Simos PG,Breier JI,Maggio WW,Gormley WB,Zouridakis G,Willmore LJ,Wheless JW,Constantinou JE,Papanicolaou AC

更新日期：1999-01-18 00:00:00

abstract：:Amyloid precursor protein binding protein-1 (APP-BP1) was first identified as an interacting protein of APP. In this study, we explored whether APP-BP1 plays a role in neuronal differentiation of fetal neural stem cells. APP-BP1 knockdown by small interfering RNA treatment was found to downregulate neuronal differenti...

journal_title：Neuroreport

authors： Hong BH,Ha S,Joo Y,Kim JA,Chang KA,Woo RS,Suh YH,Kim JH,Kim HS

更新日期：2012-01-25 00:00:00

abstract：:When examining a buying process, changes in human brain signals and their event-related potential (ERP) components can be considered a reflection of the consumers' emotions. In this experiment, participants were shown 12 products and related services that were available for purchase. After recording ERP components, we...

journal_title：Neuroreport

authors： Zhao M,Wang J,Han W

更新日期：2015-12-02 00:00:00

abstract：:Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation and nerve injury. Recent evidence has also suggested the critical role of an epigenetic mechanism in ...

journal_title：Neuroreport

authors： Li K,Zhao GQ,Li LY,Wu GZ,Cui SS

更新日期：2014-10-01 00:00:00

abstract：:The present study assessed the binding characteristics of [125I]angiotensin II to slices of human cerebellum adhered to glass slides using quantitative receptor autoradiography. Specific [125I]angiotensin II binding, defined by the inclusion of unlabelled angiotensin II (1.0 microM), was detected in the molecular laye...

journal_title：Neuroreport

authors： Barnes JM,Barber PC,Barnes NM

更新日期：1991-10-01 00:00:00

abstract：:Recently, we have demonstrated that bone marrow stem cells can differentiate into retinal nerve cells. In the present study, we show a new and efficient strategy for transplanting bone marrow stem cells into the retina. When bone marrow stem cells were injected into the vitreous cavity of untreated eyes, only very few...

journal_title：Neuroreport

authors： Minamino K,Adachi Y,Yamada H,Higuchi A,Suzuki Y,Iwasaki M,Nakano K,Koike Y,Mukaide H,Kiriyama N,Shigematsu A,Matsumura M,Ikehara S

更新日期：2005-08-22 00:00:00

abstract：:In this study, we determined whether the visuospatial attention network of frontal, parietal, and occipital cortex can be parsed into two different subsets of active regions associated with transient and sustained processes within the same cue-to-target delay period of an endogenously cued visuospatial attention task....

journal_title：Neuroreport

authors： Luks TL,Sun FT,Dale CL,Miller WL,Simpson GV

更新日期：2008-01-22 00:00:00

abstract：:We evaluated the incentive motivational properties of MK-801 by determining its priming effect on drug-seeking behaviour following extinction of cocaine self-administration, an animal model for drug craving. Rats were allowed to self-administrate cocaine (0.5 mg/kg) or saline during 10 daily sessions. MK-801 (0.1-0.25...

journal_title：Neuroreport

authors： De Vries TJ,Schoffelmeer AN,Binnekade R,Mulder AH,Vanderschuren LJ

更新日期：1998-03-09 00:00:00

abstract：:Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein in CNS-type cells had an effect on mitochondria. We found abnormal mo...

journal_title：Neuroreport

authors： Grant SM,Shankar SL,Chalmers-Redman RM,Tatton WG,Szyf M,Cuello AC

更新日期：1999-01-18 00:00:00

abstract：:Deficits of working memory (WM) are recognized as an important pathological feature in schizophrenia. Since the P600 component of event related potentials has been hypothesized that represents aspects of second-pass parsing processes of information processing, and is related to WM, the present study focuses on P600 el...

journal_title：Neuroreport

authors： Papageorgiou C,Kontaxakis VP,Havaki-Kontaxaki BJ,Stamouli S,Vasios C,Asvestas P,Matsopoulos GK,Kontopantelis E,Rabavilas A,Uzunoglu N,Christodoulou GN

更新日期：2001-09-17 00:00:00

abstract：:Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET(B) receptor and an ama...

journal_title：Neuroreport

authors： Hansen-Schwartz J,Edvinsson L

更新日期：2000-02-28 00:00:00

abstract：:Recent experiments have suggested that the process of visuomotor adaptation depends on how a visual distortion is introduced. The cerebellum is thought to be involved in adapting to rapidly introduced visual distortions; however its role in adapting to a gradually introduced distortion is unknown. We tested adaptation...

journal_title：Neuroreport

authors： Robertson EM,Miall RC

更新日期：1999-04-06 00:00:00

abstract：:As treatment of ischemic stroke remains a challenge with respect to the failure of numerous neuroprotective attempts, there is an ongoing need for better understanding of pathophysiological mechanisms causing tissue damage. Although ischemic outcomes have been studied extensively at the cellular and molecular level us...

journal_title：Neuroreport

authors： Michalski D,Härtig W,Krueger M,Hobohm C,Käs JA,Fuhs T

更新日期：2015-07-08 00:00:00

abstract：:Cultured cerebellar granule neurons were used to examine the hypothesis that NMDA or KCl-dependent Ca2+ influx activates a signaling cascade mediating transcription, translation and assembly of neurofilaments. The data indicate that 25 mM KCl and 140 microM NMDA induce neurofilament protein, mRNA, and assembly in neur...

journal_title：Neuroreport

authors： Bui CJ,Beaman-Hall CM,Vallano ML

更新日期：2003-11-14 00:00:00

abstract：:Sleep disorders increase with ageing. The serotonergic system has been linked with sleep regulation. In fatal familial insomnia, a prion disease with insomnia as one major clinical feature, we recently observed a disturbance in the serotonergic system as likely substrate of typical symptoms. Using immunohistochemistry...

journal_title：Neuroreport

authors： Klöppel S,Kovacs GG,Voigtländer T,Wanschitz J,Flicker H,Hainfellner JA,Guentchev M,Budka H

更新日期：2001-03-26 00:00:00

abstract：:Acid-sensing ion channels (ASICs) constitute a branch of the super-gene family of amiloride-sensitive sodium channels. So far five different ASICs have been cloned from mammalian tissues. They are activated by a drop of extracellular pH but differ with respect to effective agonist concentration, desensitization and mR...

journal_title：Neuroreport

authors： Gründer S,Geissler HS,Bässler EL,Ruppersberg JP

更新日期：2000-06-05 00:00:00

abstract：:A lexical decision experiment was conducted while event related potentials (ERPs) were recorded. The word frequency and the first syllable frequency of each word were manipulated. Results showed that, while high frequency words produced less negative amplitudes in the N400 time window than low frequency words, the inv...

journal_title：Neuroreport

authors： Barber H,Vergara M,Carreiras M

更新日期：2004-03-01 00:00:00