Functional imaging of brain activity in conscious monkeys responding to sexually arousing cues.

abstract：:We investigated the protective effects of edaravone, a free radical scavenger, against ischemic damage of inner hair cells (IHCs) in gerbils. Cochlear ischemia was induced in the animals by occluding the vertebral arteries bilaterally for 15 min. Edaravone (1 mg/kg, i.v.) or saline was administered 1 h after ischemia....

journal_title：Neuroreport

authors： Maetani T,Hakuba N,Taniguchi M,Hyodo J,Shimizu Y,Gyo K

更新日期：2003-10-06 00:00:00

abstract：:We examined the biology of AMPA/kainate-induced motor neuron degeneration using dissociated spinal cord cultures and motor neuron-specific antibodies which enable characterization of individual motor neurons in culture. Cobalt, which is thought to pass through Ca2+-permeable AMPA/kainate receptors following kainate ex...

journal_title：Neuroreport

authors： Bar-Peled O,O'Brien RJ,Morrison JH,Rothstein JD

更新日期：1999-03-17 00:00:00

abstract：:Homotopic and isochronic transplantation of the alar plate of the rhombomeres 7 and 8 was performed between chick and quail embryos at the stage of 10-14 somites. Analysis of the graft derivatives in 12-day-old chimeric embryos by means of the quail nucleolar marker showed that the ipsilateral inferior olive is formed...

journal_title：Neuroreport

authors： Ambrosiani J,Armengol JA,Martinez S,Puelles L

更新日期：1996-05-17 00:00:00

abstract：:We used isolated IgG antibodies selective for P2X3 receptors to study the ultrastructural distribution of these receptors in rat sensory neurons. In trigeminal ganglia, P2X3 receptor immunoreactivity occurred in small and large nerve cell bodies and their processes. Endoplasmic reticulum and Golgi apparatus were heavi...

journal_title：Neuroreport

authors： Llewellyn-Smith IJ,Burnstock G

更新日期：1998-08-03 00:00:00

abstract：:Age-related depletion of androgens in men results in functional impairments in androgen-responsive tissues, such as the brain, resulting in increased risk for Alzheimer's disease. To investigate the relationship between normal age-related hormone loss and Alzheimer's disease risk, we evaluated the brain and serum leve...

journal_title：Neuroreport

authors： Rosario ER,Chang L,Beckett TL,Carroll JC,Paul Murphy M,Stanczyk FZ,Pike CJ

更新日期：2009-11-25 00:00:00

abstract：:GLAST is a glial glutamate transporter; mRNA for a splice variant, GLAST1a, which lacks exon 3, has previously been identified. To detect GLAST1a protein, we generated antibodies against a peptide sequence encompassing the splice site. We demonstrate by Western blotting and immunocytochemistry the expression of GLAST1...

journal_title：Neuroreport

authors： Macnab LT,Williams SM,Pow DV

更新日期：2006-12-18 00:00:00

abstract：:Serotonin (5-HT) is known to reduce apoptosis and in rodent models of brain ischemia. Modulation of programmed cell death during neural development was assessed in early postnatal brains of serotonin transporter (5-HTT) knockout mice, characterized by elevated extracellular 5-HT levels. The number of apoptotic cells v...

journal_title：Neuroreport

authors： Persico AM,Baldi A,Dell'Acqua ML,Moessner R,Murphy DL,Lesch KP,Keller F

更新日期：2003-03-03 00:00:00

abstract：:The hypothesis of a general (i.e. cross-modal) temporal processing deficit in dyslexia was tested by examining rapid processing in both the auditory and the visual system in the same children with dyslexia. Participants were 10- to 12-year-old dyslexic readers and age-matched normal reading controls. Psychophysical th...

journal_title：Neuroreport

authors： Van Ingelghem M,van Wieringen A,Wouters J,Vandenbussche E,Onghena P,Ghesquière P

更新日期：2001-11-16 00:00:00

abstract：:The brain constructs multiple representations of near and far space but it is unclear which spatial mechanism guides reaching across eye movements in near space. Retinocentric reaching representations are known to exist in parietal cortex, but must be updated during eye movements, in order to remain accurate. In contr...

journal_title：Neuroreport

authors： Medendorp WP,Crawford JD

更新日期：2002-04-16 00:00:00

abstract：:Insulin-like growth factor (IGF)-I is essential for cerebellar granule neuron survival and a decline in IGF-I is implicated in various age-dependent processes. Here we show that IGF-I mRNA levels are decreased in the cerebellum of old rats compared with young rats and this was associated with increased cell death and ...

journal_title：Neuroreport

authors： Pañeda C,Arroba AI,Frago LM,Holm AM,Rømer J,Argente J,Chowen JA

更新日期：2003-08-26 00:00:00

abstract：:Calcium increases induced by single action potentials in rat visual cortex layer II/III pyramidal neurons were shown to be augmented by muscarinic acetylcholine receptor (mAchR) stimulation. This augmentation was drastically reduced by intracellular injection of heparin but not ruthenium red, therefore involving inosi...

journal_title：Neuroreport

authors： Yamamoto K,Hashimoto K,Isomura Y,Shimohama S,Kato N

更新日期：2000-02-28 00:00:00

abstract：:It has been suggested that high levels of prenatal testosterone exposure are implied in the aetiology of dyslexia and its frequently co-occurring sensory problems. This study examined 2D : 4D digit ratio (a marker of fetal testosterone exposure) in dyslexic and normal reading children. No group differences in 2D : 4D ...

journal_title：Neuroreport

authors： Boets B,De Smedt B,Wouters J,Lemay K,Ghesquière P

更新日期：2007-09-17 00:00:00

abstract：:Extracellular pH transients were evoked in rat hippocampal brain slices by activation of a monosynaptic inhibitory pathway following pharmacological blockade of glutaminergic transmission. Repetitive stimulation in stratum radiatum near the recording site in stratum pyramidale evoked an immediate alkaline shift which ...

journal_title：Neuroreport

authors： Kaila K,Paalasmaa P,Taira T,Voipio J

更新日期：1992-01-01 00:00:00

abstract：:To investigate the phonological influences on the lexicosemantic process with a strong orthographic constraint, we used kanji (morphogram) homophone words and measured, using magnetoencephalography, the neural activities during the silent reading of prime-target pairs. The primes were phonologically the same as or dif...

journal_title：Neuroreport

authors： Wei Q,Ihara A,Hayakawa T,Murata T,Matsumoto E,Fujimaki N

更新日期：2007-11-19 00:00:00

abstract：:Epidemiological data show correlations between hypercholesterolemia and Alzheimer's disease (AD). We test the hypothesis that hypercholesterolemia modulates Abeta deposition in mice overexpressing the human APP695 Swedish mutation (K670N and M671L) (TgAPPsw). Feeding mice a high fat/high cholesterol (HFHC) diet for 7-...

journal_title：Neuroreport

authors： Shie FS,Jin LW,Cook DG,Leverenz JB,LeBoeuf RC

更新日期：2002-03-25 00:00:00

abstract：:To define the significance of glutamate ionotropic receptors in sPLA -mediated neuronal cell death we used the NMDA receptor antagonist MK-801 and the AMPA receptor antagonist PNQX. In primary neuronal cell cultures both MK-801 and PNQX inhibited sPLA - and glutamate-induced neuronal death. [ H]Arachidonic acid releas...

journal_title：Neuroreport

authors： Kolko M,de Turco EB,Diemer NH,Bazan NG

更新日期：2002-10-28 00:00:00

abstract：:The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...

journal_title：Neuroreport

authors： Zatta P,Zambenedetti P,Bruna V,Filippi B

更新日期：1994-09-08 00:00:00

abstract：:This study investigated whether mild birth complications (C-section birth, C-section + 15 min global anoxia) interact with stress at adulthood to modulate levels of [3H]WIN 35428 binding to dopamine transporters (DAT) in rat brain. Without stress, adult C-sectioned rats showed increased DAT binding in the dorsal stria...

journal_title：Neuroreport

authors： El-Khodor BF,Boksa P

更新日期：2002-02-11 00:00:00

abstract：:Transplantation of olfactory ensheathing cells (OECs) into photochemically damaged rat spinal cord diminished astrocyte reactivity and parenchyma cavitation. The photochemical lesion performed at T12--L1 resulted in severe damage to the spinal cord, so that during the first 15 days postoperation all rats dragged their...

journal_title：Neuroreport

authors： Verdú E,García-Alías G,Forés J,Gudiño-Cabrera G,Muñetón VC,Nieto-Sampedro M,Navarro X

更新日期：2001-08-08 00:00:00

abstract：:In this study it was shown that in adults, the frequency characteristics of EEG preceding stimuli that were followed by incorrect responses were different from the characteristics of EEG preceding stimuli that were followed by correct responses. In the recording during three different tasks that explore different neur...

journal_title：Neuroreport

authors： Fernández T,Harmony T,Silva-Pereyra J,Fernández-Bouzas A,Gersenowies J,Galán L,Carbonell F,Marosi E,Otero G,Valdés SI

更新日期：2000-08-21 00:00:00

abstract：:We measured regional cerebral blood flow using positron emission tomography in seven normal volunteers during discrimination tasks for visual patterns. For the 'attention to right or left' tasks, the subjects were instructed to press a key when sample and test stimuli presented in the right or left visual fields, resp...

journal_title：Neuroreport

authors： Kawashima R,Satoh K,Goto R,Inoue K,Itoh M,Fukuda H

更新日期：1998-05-11 00:00:00

abstract：:Previous studies have demonstrated induced gamma-band activity (GBA) over posterior temporo-parietal and inferior frontal cortex during auditory spatial vs pattern mismatch processing, respectively. Here we investigated magnetoencephalographic oscillatory responses during an active auditory pattern oddball task. Fourt...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W

更新日期：2004-10-05 00:00:00

abstract：:We examined the effect of a nonphotic stimulus (running in a novel wheel) on the induction of Fos-related proteins in the two well-established neural components of the circadian clock: the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) of the lateral geniculate complex. There was no induction of F...

journal_title：Neuroreport

authors： Janik D,Mrosovsky N

更新日期：1992-07-01 00:00:00

abstract：:With the purpose of mapping representations of the finger and proximal arm in the human primary motor cortex (MI), we measured regional cerebral blood flow (rCBF) in eight right-handed normal volunteers during self-paced finger and proximal arm movements. Each movement activated two different fields in MI, one located...

journal_title：Neuroreport

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Yanagisawa T

更新日期：1995-01-26 00:00:00

abstract：:Emerging evidence has suggested that alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) protects neurons from glutamate-induced neurotoxicity. In this study, we examined the effect of AMPA on the cell surface expression of the N-methyl-D-aspartate (NMDA) receptor, a central player in glutamate-induced neurot...

journal_title：Neuroreport

authors： Nishimoto T,Kihara T,Akaike A,Niidome T,Sugimoto H

更新日期：2009-01-28 00:00:00

abstract：:Investigating activity-dependent plasticity in the auditory brain stem of the adult rat, we observed that electrical intracochlear stimulation led to a tonotopically localized modulation of the phosphorylation of the cAMP response element binding protein (CREB) and an equally localized expression of the immediate earl...

journal_title：Neuroreport

authors： Illing RB,Michler SA

更新日期：2001-03-26 00:00:00

abstract：:The mismatch negativity (MMN) reflects the neural representation of the acoustic environment stored in sensory memory. The short phase of sensory memory corresponds to the temporal window of integration (TWI) which integrates the neighboring sounds into a unitary event. We measured the magnetic MMN (MMNm) and the disc...

journal_title：Neuroreport

authors： Yabe H,Asai R,Hiruma T,Sutoh T,Koyama S,Kakigi R,Tervaniemi M,Kaneko S

更新日期：2004-12-22 00:00:00

abstract：:Fourteen healthy right-handed subjects were scanned using PET with a [15O]water tracer during exposure to electromagnetic field (EMF) emitted by a mobile phone and a sham-exposure under double-blind conditions. During scanning, the subjects performed a visual working memory task. Exposure to an active mobile phone pro...

journal_title：Neuroreport

authors： Haarala C,Aalto S,Hautzel H,Julkunen L,Rinne JO,Laine M,Krause B,Hämäläinen H

更新日期：2003-11-14 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF) attracts considerable attention because it supports survival and differentiation of various types of neurons and glial cells in vitro. Although CNTF functions as a moderate neurotrophic factor in mature motor neurons, its role in embryonic development remains unknown. Here, we found ...

journal_title：Neuroreport

authors： Hata K,Araki M,Yamamori T

更新日期：2002-04-16 00:00:00

abstract：:A combined microdialysis/microinfusion technique was used to investigate whether arginine vasopressin (AVP) is involved in the regulation of its own release into the extracellular fluid of the supraoptic nucleus in vivo. While intranuclear neuropeptide release was monitored, 0.33 microliter of either vehicle, lysine v...

journal_title：Neuroreport

authors： Wotjak CT,Ludwig M,Landgraf R

更新日期：1994-06-02 00:00:00