Psychophysical evidence for a general temporal processing deficit in children with dyslexia.

abstract：:The balance between heat production (metabolism) and heat removal (blood flow) helps in keeping the temperature of the brain constant. In patients with moyamoya disease, this balance may be disturbed. The purpose of this study was to assess the thermal pathophysiology of the brain in patients with moyamoya disease. Th...

journal_title：Neuroreport

authors： Yamada K,Sakai K,Akazawa K,Yuen S,Sugimoto N,Sasajima H,Mineura K,Nishimura T

更新日期：2010-09-15 00:00:00

abstract：:Although the role of Bcl-2-related proteins as regulators of the apoptotic process has been well documented, recent studies suggest that they might also be implicated in neuronal differentiation. We have studied by immunocytochemistry, Western blotting and RT-PCR the expression pattern of Bcl-xL, Bcl-2 and BAX in the ...

journal_title：Neuroreport

authors： Guillemain I,Gaboyard S,Fontès G,Saunier M,Privat A,Patey G

更新日期：2000-05-15 00:00:00

abstract：:The serotonin transporter is a strong candidate for aetiological involvement in affective disorders and psychosis. We analysed a VNTR in intron 2 of the human serotonin transporter gene (hSERT) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. An increased frequency of all...

journal_title：Neuroreport

authors： Collier DA,Arranz MJ,Sham P,Battersby S,Vallada H,Gill P,Aitchison KJ,Sodhi M,Li T,Roberts GW,Smith B,Morton J,Murray RM,Smith D,Kirov G

更新日期：1996-07-08 00:00:00

abstract：:Apolipoprotein E (apoE) and the beta-amyloid peptide are both found in the senile plaques associated with Alzheimer's disease. Several studies have recently determined that apoE can prevent beta-amyloid fibril (Abetaf) formation in vitro. In vivo, apoE is normally associated with a lipid source. We show that both reco...

journal_title：Neuroreport

authors： Beffert U,Poirier J

更新日期：1998-10-05 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are hetero-oligomeric receptor-channel complexes composed of NR1 and NR2 subunits. Subunit composition determines the properties of NMDA receptor subtypes. However, the molecular mechanisms regulating their subunit composition are unknown. Using reverse transcription (RT)-competit...

journal_title：Neuroreport

authors： Hoffmann H,Hatt H,Gottmann K

更新日期：1997-12-01 00:00:00

abstract：:Adrenocorticotropic hormone (ACTH) is a member of the opiocortin family of peptides. Within the central nervous system, ACTH-synthesizing neurons are generally considered to be located within the hypothalamus and are known to be involved in the neural circuitry underlying the integration of stress responses. We now re...

journal_title：Neuroreport

authors： Güntürkün O,Deviche P

更新日期：1992-02-01 00:00:00

abstract：:When we perform a visually guided reaching action, the brain coordinates our hand and eye movements. Eye-hand coordination has been examined widely, but it remains unclear whether the hand and eye motor systems are coordinated during on-line visuomotor adjustments induced by a target jump during a reaching movement. A...

journal_title：Neuroreport

authors： Abekawa N,Inui T,Gomi H

更新日期：2014-05-07 00:00:00

abstract：:Amyotrophic lateral sclerosis is a devastating motor neuron disorder. Traditionally regarded as a 'neuron only' disease, recent evidence suggested that other cells contribute critically to the pathogenesis. This review provides a short synopsis of the role neuroinflammation and microglial cells play in the disease and...

journal_title：Neuroreport

authors： Weydt P,Möller T

更新日期：2005-04-25 00:00:00

abstract：:The aim of this study was to reveal a potential effect of emotion on cognitive control in the implicit memory task with emotionally neutral and unpleasant words in healthy controls and patients with schizophrenia using a 3.0 T functional MRI (fMRI). A total of 15 patients with schizophrenia and 15 healthy controls und...

journal_title：Neuroreport

authors： Kim GW,Yang JC,Jeong GW

更新日期：2015-08-05 00:00:00

abstract：:In an earlier study, we reported the antinociceptive effects of a special repetitive transcranial magnetic stimulation paradigm: continuous theta-burst stimulation (cTBS), when applied to human motor cortex. Here, we investigated whether the reduced subjective pain perception of 10 healthy individuals could be measure...

journal_title：Neuroreport

authors： Csifcsak G,Nitsche MA,Baumgärtner U,Paulus W,Treede RD,Antal A

更新日期：2009-08-05 00:00:00

abstract：:AMPA (EC50 = 1.0 x 10(-6) M) and NMDA (EC50 = 1.3 x 10(-4) M) trigger 45Ca2+ influx in 13-day chick embryonic retinal explants. This agonist-driven cationic flux is specifically inhibited by typical competitive antagonists, such as 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 2-amino-7-phosphonoheptanoate (AP7), respec...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramírez G

更新日期：2000-07-14 00:00:00

abstract：:Auditory evoked magnetic fields were recorded with a 24-SQUID magnetometer on a patient with a vascular lesion in the right auditory cortex and its vicinity. The contralateral transient 100 ms response (N100m) was absent over the damaged side, with no recovery within 16 months. Responses were normal over the healthy s...

journal_title：Neuroreport

authors： Mäkelä JP,Hari R

更新日期：1992-01-01 00:00:00

abstract：:In the present study, the activity changes of chicken retinal ganglion cells in response to light stimuli with defined contrast were investigated, in the presence of various levels of sustained background illumination. Following a step increase of light illumination, the firing rate of most retinal ganglion cells incr...

journal_title：Neuroreport

authors： Chen AH,Zhou Y,Gong HQ,Liang PJ

更新日期：2005-03-15 00:00:00

abstract：:I have investigated the role of Ca2+ on M-current (IK(M)) inhibition by the muscarinic agonist oxo-M using the perforated patch voltage clamp technique. Oxo-M inhibited IK(M) in cultured SCG cells with an IC50 of 1.2 microM in 2 mM [Ca2+]o, and 13.1 microM in nominally Ca(2+)-free external solution. BAPTA-AM, ryanodin...

journal_title：Neuroreport

authors： Lamas JA

更新日期：1999-08-02 00:00:00

abstract：:It has been repeatedly demonstrated that schizophrenic patients are impaired in the comprehension of sentences with complex syntax. We investigated the hypothesis that this syntactic comprehension impairment in schizophrenia is not a purely linguistic dysfunction, but rather the reflection of a cognitive sequence proc...

journal_title：Neuroreport

authors： Lelekov T,Franck N,Dominey PF,Georgieff N

更新日期：2000-07-14 00:00:00

abstract：:We previously reported that clusterin enhances astrocyte proliferation and extracellular signal-regulated kinase (ERK) activity. It, however, remains largely unknown how clusterin promotes cell growth. Here, we investigate the signaling pathway and related molecules underlying astrocyte proliferation by clusterin. Exo...

journal_title：Neuroreport

authors： Shim YJ,Shin YJ,Jeong SY,Kang SW,Kim BM,Park IS,Min BH

更新日期：2009-03-04 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:Recent studies have demonstrated a loss of cannabinoid CB1 receptors in the basal ganglia in Huntington's disease (HD), but there are no data on endocannabinoid levels in this disease. In the present study, we have addressed this question by using rats with bilateral intrastriatal injections of 3-nitropropionic acid (...

journal_title：Neuroreport

authors： Lastres-Becker I,Fezza F,Cebeira M,Bisogno T,Ramos JA,Milone A,Fernández-Ruiz J,Di Marzo V

更新日期：2001-07-20 00:00:00

abstract：:To compare the maximum Hoffmann reflex (H-reflex) and the maximum M-wave (H : M) ratio of the H-reflex in men and women when all participants showed similar saliva levels of estradiol and progesterone. This is a cohort design study involving healthy men and women with a mean age of 22.4±3.4 years. The H : M ratio of t...

journal_title：Neuroreport

authors： Hoffman M,Norcross M,Johnson S

更新日期：2018-03-07 00:00:00

abstract：:Addition of the beta-hydroxy-beta-methylglutaryl-CoA (HmG-CoA) reductase inhibitor lovastatin to human HEK cells transfected with the amyloid precursor protein (APP) reduces intracellular cholesterol/protein ratios by 50%, and markedly inhibits beta-secretase cleavage of newly-synthesized APP. Exogenous water-solubili...

journal_title：Neuroreport

authors： Frears ER,Stephens DJ,Walters CE,Davies H,Austen BM

更新日期：1999-06-03 00:00:00

abstract：:Reward-processing neurocircuitry has been delineated using verbal or visual processing and/or decision-making tasks. We examined more basic processes of listening to enjoyable music in healthy and depressed patients. The paradigm was passive, individualized, and brief. Sixteen depressed and 15 control individuals prov...

journal_title：Neuroreport

authors： Osuch EA,Bluhm RL,Williamson PC,Théberge J,Densmore M,Neufeld RW

更新日期：2009-08-26 00:00:00

abstract：:We investigated the roles of the auditory cortex in discrimination learning of vowel-like sounds consisting of multiple formants. Rats were trained to discriminate between synthetic sounds with four formants. Bilateral electrolytic lesions including the primary auditory cortex and the dorsal auditory association corte...

journal_title：Neuroreport

authors： Kudoh M,Nakayama Y,Hishida R,Shibuki K

更新日期：2006-11-27 00:00:00

abstract：:Salidroside (SDS), a phenylpropanoid glycoside isolated from Rhodiola rosea L., has been reported to be neuroprotective in vitro, which raises the possibility of using SDS as a neuroprotective agent after nerve injuries. In the present study, the possibly beneficial effect of SDS on promoting nerve regeneration after ...

journal_title：Neuroreport

authors： Sheng QS,Wang ZJ,Zhang J,Zhang YG

更新日期：2013-03-27 00:00:00

abstract：:We investigated the mode of action of argiotoxin636 on isolated N-methyl-D-aspartate (NMDA) receptor channels in cultured cerebellar granule cells. We found that the toxin blocks NMDA channels by decreasing their opening probability and by inducing a flickering activity, in a voltage-dependent manner. Our results indi...

journal_title：Neuroreport

authors： Fagni L,Bockaert J

更新日期：1995-05-09 00:00:00

abstract：:Diffusion tensor imaging was used to measure regional differences in brain white matter microstructure (intravoxel coherence) and macrostructure (intervoxel coherence) and age-related differences between men and women. Neuropsychiatrically healthy men and women, spanning the adult age range, showed the same pattern of...

journal_title：Neuroreport

authors： Sullivan EV,Adalsteinsson E,Hedehus M,Ju C,Moseley M,Lim KO,Pfefferbaum A

更新日期：2001-01-22 00:00:00

abstract：:The Stroop effect refers to an increase in response time observed when the word meaning and the stimulus hue do not match. In an incongruent condition, the word 'green' is presented in the color red, whereas in a congruent condition the word 'red' is presented in the color red. To determine at what level of processing...

journal_title：Neuroreport

authors： Xiao X,Qiu J,Zhang Q

更新日期：2009-05-06 00:00:00

abstract：:Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis. We presently evaluated neural progenitor proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus, subventricular zone, and the posterior periventricle in the brains of IL-6 knockout mice and their wild-type l...

journal_title：Neuroreport

authors： Bowen KK,Dempsey RJ,Vemuganti R

更新日期：2011-02-16 00:00:00

abstract：:Caspase-2 has features of both initiator and effector caspases. Previously, we have shown that brain hypoxia-induced production of caspases 1, 3, 8, and 9 is Src kinase mediated, a nonreceptor intracellular family of kinases. The present study tests the hypothesis that hypoxia results in increased expression of caspas...

journal_title：Neuroreport

authors： Angelis D,Delivoria-Papadopoulos M

更新日期：2017-08-16 00:00:00

abstract：:Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural...

journal_title：Neuroreport

authors： Kéri S,Gulyás B

更新日期：2003-06-11 00:00:00

abstract：:This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not g...

journal_title：Neuroreport

authors： Murrell W,Bushell GR,Livesey J,McGrath J,MacDonald KP,Bates PR,Mackay-Sim A

更新日期：1996-04-26 00:00:00