Differential expression of Bcl-2-related proteins in differentiating NT2 cells.

abstract：:This study examined the long-term effects of the antidepressant escitalopram on rat serotonin (5-HT) neuronal activity and hippocampal neuroplasticity. In the dorsal raphe nucleus, a 2-week treatment with escitalopram (10 mg/kg/day, subcutaneous) did not modify the firing activity of 5-HT neurons, whereas a cotreatmen...

journal_title：Neuroreport

authors： Mnie-Filali O,Faure C,Mansari ME,Lambás-Señas L,Bérod A,Zimmer L,Sánchez C,Haddjeri N

更新日期：2007-10-08 00:00:00

abstract：:The present study reveals the presence of a distinct group of cells, resembling reticular thalamic neurones, in the internal capsule during fetal development. This cell population rapidly decreases in size during early infancy and few cells are apparent in the 1-year-old infant. Internal capsule cells are well differe...

journal_title：Neuroreport

authors： Letinić K,Kostović I

更新日期：1996-09-02 00:00:00

abstract：:Unilateral 6-hydroxydopamine lesion to rat substantia nigra pars compacta resulted in a modest, but significant, decrease in the specific binding of N-alpha-[methyl-3H]histamine (19 +/- 5% reduction) to synaptosomal membranes from ipsilateral striata. Dopamine synthesis was assessed in striatal slices by determining [...

journal_title：Neuroreport

authors： Molina-Hernández A,Nuñez A,Arias-Montaño JA

更新日期：2000-01-17 00:00:00

abstract：:High homocysteine serum level has been regarded as one of the important factors that influence the development of schizophrenia. Genetic variations of methylenetetrahydrofolate reductase, which is a main enzyme reducing homocysteine level, are reported in schizophrenic patients. We measured the serum level of homocyst...

journal_title：Neuroreport

authors： Lee YS,Han DH,Jeon CM,Lyoo IK,Na C,Chae SL,Cho SC

更新日期：2006-05-15 00:00:00

abstract：:We examined the cortical areas showing increased activation related to axis orientation discrimination in hand movement and perception by positron emission tomography (PET) in right-handed normal human subjects while they performed a hand orientation (HO) task and an orientation discrimination (OD) task. In the OD tas...

journal_title：Neuroreport

authors： Taira M,Kawashima R,Inoue K,Fukuda H

更新日期：1998-01-26 00:00:00

abstract：:Eleven early-onset dementia families, all with affected individuals who have either presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have been confirmed to have EOFAD by autopsy, and two early onset cases with biopsy-confirmed AD pathology, were screened for missense mutations in the ...

journal_title：Neuroreport

authors： Kwok JB,Taddei K,Hallupp M,Fisher C,Brooks WS,Broe GA,Hardy J,Fulham MJ,Nicholson GA,Stell R,St George Hyslop PH,Fraser PE,Kakulas B,Clarnette R,Relkin N,Gandy SE,Schofield PR,Martins RN

更新日期：1997-04-14 00:00:00

abstract：:Bilateral voluntary contractions involve functional changes in both primary motor cortices. However how the unilateral voluntary contraction of hand muscles influences the contralateral corticomuscular synchronous oscillations mechanisms remains unclear. In the bimanual tasks, nine healthy subjects were instructed to ...

journal_title：Neuroreport

authors： Li S,Fan M,Yu H,Gao L

更新日期：2020-03-04 00:00:00

abstract：:Extracellular recordings were used to determine the effects of cannabinoids on the activity of dopamine neurons within the ventral tegmental area (VTA) and substantia nigra pars compacta (SNC). Systemic administration of the natural psychoactive cannabinoid delta 9-tetrahydrocannabinol (delta 9-THC) and the synthetic ...

journal_title：Neuroreport

authors： French ED,Dillon K,Wu X

更新日期：1997-02-10 00:00:00

abstract：:The spatial-temporal expression and function of Drosophila melanogaster homothorax (hth) and its vertebrate homologue Meis2 in the eye anlage show a high degree of evolutionary conservation. Both are expressed by progenitor cells ahead of the neurogenic wave front, promote rapid proliferation of these cells, and are d...

journal_title：Neuroreport

authors： Heine P,Dohle E,Schulte D

更新日期：2009-02-18 00:00:00

abstract：:Thyroid hormone receptor beta2 (TRbeta2) controls the patterning of cone opsin photopigments that mediate colour vision. We raised an antiserum against TRbeta2 to study cone photoreceptor development by western blot and immunostaining analyses. TRbeta2-positive cells first appeared between embryonic day 10 (E10) and E...

journal_title：Neuroreport

authors： Ng L,Ma M,Curran T,Forrest D

更新日期：2009-04-22 00:00:00

abstract：:In primary cultures from rat cerebral cortex, pituitary adenylate cyclase-activating polypeptide (PACAP-38) exerted a protective effect on cell death induced by the excitotoxin NMDA in neuron-enriched cultures and also on apoptotic cell death induced by serum deprivation in mixed neuronal-glial cultures. The neuroprot...

journal_title：Neuroreport

authors： Frechilla D,García-Osta A,Palacios S,Cenarruzabeitia E,Del Rio J

更新日期：2001-04-17 00:00:00

abstract：:Widespread invasiveness, represented by the invasion and migration, is the most important characteristic of glioblastoma multiforme (GBM) and is the main reason for therapeutic failure and recurrence of the tumor. Hypoxia is one of the main microenvironment in determining tumor invasiveness. Therefore, intense efforts...

journal_title：Neuroreport

authors： Huang W,Ding X,Ye H,Wang J,Shao J,Huang T

更新日期：2018-12-12 00:00:00

abstract：:Numerous reports have shown that cyclin-dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, critically contributes to the induction and maintenance of chronic pain induced by peripheral inflammation and nerve injury. Recent evidence has also suggested the critical role of an epigenetic mechanism in ...

journal_title：Neuroreport

authors： Li K,Zhao GQ,Li LY,Wu GZ,Cui SS

更新日期：2014-10-01 00:00:00

abstract：:The developmental time-course of type I and type II benzodiazepine receptors in the chick optic lobe was determined using a triazolopyridazine, CL 218872. At embryonic day 13 most of the binding sites corresponded to type II (98.23%), while type I represented only a minor proportion (1.77%). During development there w...

journal_title：Neuroreport

authors： Gravielle MC,de Plazas SF

更新日期：1995-10-23 00:00:00

abstract：:To examine the relationship between plasma lipoproteins and apolipoproteins in men with convictions for violent offences, blood was obtained from 15 men with a history of violence who were serving prison sentences for violent offences, and 25 age-matched male controls from the staff of the Argyll and Bute Psychiatric ...

journal_title：Neuroreport

authors： Gray RF,Corrigan FM,Strathdee A,Skinner ER,van Rhijn AG,Horrobin DF

更新日期：1993-06-01 00:00:00

abstract：:Where and how the cortical areas are activated when a person receives the result of hypothesis testing is still unclear. By using a category induction task, this study provided participants with various batteries and asked them to learn which kind of batteries were charged. After learning, they were required to give a...

journal_title：Neuroreport

authors： Li F,Cao B,Lei Y,Li H

更新日期：2009-01-28 00:00:00

abstract：:Peripheral nerve injury therapy in the clinic remains less than satisfactory. The gold standard of treatment for long peripheral nerve defects is autologous nerve grafts; however, numerous clinical complications are associated with this treatment. As tissue engineering has developed, tissue-engineered nerve grafts (TE...

journal_title：Neuroreport

authors： Yan L,Yao Z,Lin T,Zhu Q,Qi J,Gu L,Fang J,Zhou X,Liu X

更新日期：2017-10-18 00:00:00

abstract：:It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...

journal_title：Neuroreport

authors： Hirai D,Hosokawa T,Inoue M,Miyachi S,Mikami A

更新日期：2009-04-22 00:00:00

abstract：:Hyperactivity of the hypothalamic-pituitary-adrenal axis and impairment of the central corticotropin-releasing factor system are factors in the pathogenesis of depression. Though several antagonists of the corticotropin-releasing factor 1 receptor were effective in the recognized behavioral tests for antidepressant ac...

journal_title：Neuroreport

authors： Wang XB,Zhang YQ,Xue RR,Yang ZZ,Zhang XF

更新日期：2020-01-08 00:00:00

abstract：:A two-electrode voltage clamp was used to examine the effects of the local anaesthetics (LAs) lidocaine, tetracaine and bupivacaine, and the meta-isomer of lidocaine (LL33), on the gamma-aminobutyric acid (GABA)-gated Cl- channel in the crayfish stretch receptor neurone. The voltage-induced current changes were record...

journal_title：Neuroreport

authors： Nordmark J,Rydqvist B

更新日期：1997-01-20 00:00:00

abstract：:Orienting attention to a spatial location facilitates responding to a subsequent target at that location, but inhibits the response if attention is oriented away from that location before the target appears there. This inhibitory effect of attention re-orienting, called inhibition of return (IOR), occurs in vision, he...

journal_title：Neuroreport

authors： Prime DJ,Tata MS,Ward LM

更新日期：2003-03-03 00:00:00

abstract：:This study investigated the functional neuroanatomy involved in retrieval of structured versus unstructured verbal information. We compared cerebral blood flow using PET with the [15O]water method while subjects engaged in recall of novel and practised narratives and lists of unrelated words. Left orbital frontal cort...

journal_title：Neuroreport

authors： Paradiso S,Crespo Facorro B,Andreasen NC,O'Leary DS,Watkins LG,Boles Ponto L,Hichwa RD

更新日期：1997-09-29 00:00:00

abstract：:We investigated whether in vivo excitotoxicity was mediated by a mechanism of programmed cell death called apoptosis. Neurotoxic doses of kainic acid (1.2 nmol) and quinolinic acid (120 nmol) were unilaterally injected in the dorsal hippocampus of anesthetized rats. Eight or 16 h later the animals were killed and DNA ...

journal_title：Neuroreport

authors： Ignatowicz E,Vezzani AM,Rizzi M,D'Incalci M

更新日期：1991-11-01 00:00:00

abstract：:The present study examined in urethane-chloralose anaesthetized rats whether N-methyl-D-aspartate (NMDA) is involved in the depressant effect of flupirtine on the monosynaptic Hoffmann (H)-reflex recorded from plantar foot muscles and on polysynaptic flexor reflexes recorded from tibialis muscle. Intrathecal administr...

journal_title：Neuroreport

authors： Schwarz M,Block F,Pergande G

更新日期：1994-10-03 00:00:00

abstract：:Experimental animals and patients are immobilized to allow continuous monitoring of physiological parameters. Restraint stress affects brain neurotransmitter levels and induces expression of immediate early genes. Whether immobilization stress affects outcomes in newborn animals which have suffered a hypoxic-ischaemic...

journal_title：Neuroreport

authors： Thoresen M,Bågenholm R,Løberg EM,Apriccna F

更新日期：1996-01-31 00:00:00

abstract：:Traumatic brain injury (TBI) is a major risk factor for Alzheimer's disease. Recent studies suggest that amyloid-beta (Aβ) deposit can be detected several years after TBI. However, it is unknown whether post-TBI Aβ deposits arise from short-term changes in Aβ metabolism or reflect a long-term sequela. To answer this q...

journal_title：Neuroreport

authors： Bagnato S,Andriolo M,Boccagni C,Galardi G

更新日期：2017-03-22 00:00:00

abstract：:This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not g...

journal_title：Neuroreport

authors： Murrell W,Bushell GR,Livesey J,McGrath J,MacDonald KP,Bates PR,Mackay-Sim A

更新日期：1996-04-26 00:00:00

abstract：:Evidence exists that motilin immunoreactivity is highly expressed in Purkinje cells. In this study, immunohistochemistry and whole-cell patch-clamp recording were performed to investigate the spatial distribution and electrophysiological effects of motilin receptors in the cerebellum. We show here that motilin recepto...

journal_title：Neuroreport

authors： Chen H,Chen L,Wang JJ,Wei HJ,Yung WH

更新日期：2007-08-27 00:00:00

abstract：:Hemispheric (re-)organization of episodic memory functions after temporal lobe damage (TLD) was investigated by the intracarotid amobarbital procedure in patients suffering temporal lobe epilepsy. Memory of the speech-dominant left hemisphere was intact after right-sided TLD independent of the age at manifestation. In...

journal_title：Neuroreport

authors： Jokeit H,Ebner A,Holthausen H,Markowitsch HJ,Tuxhorn I

更新日期：1996-07-08 00:00:00

abstract：:This study aimed to evaluate the potential of bone marrow stromal cells for treatment of inner ear diseases. Autologous marrow cells labeled with Dil were implanted into the inner ear of five gentamicin-treated chinchillas. Histological analysis 3 weeks later revealed robust survival of grafted marrow cells in multipl...

journal_title：Neuroreport

authors： Naito Y,Nakamura T,Nakagawa T,Iguchi F,Endo T,Fujino K,Kim TS,Hiratsuka Y,Tamura T,Kanemaru S,Shimizu Y,Ito J

更新日期：2004-01-19 00:00:00