Effects of Src kinase inhibition on expression of pro-caspase-2 after brain hypoxia in a piglet animal model.

abstract：:The rat suprachiasmatic (SCN) contains a dense plexus of low-affinity p75 neurotrophin receptor (p75NTR)-immunoreactivity. In some SCN neurons, p75NTR is co-localized with vasoactive intestinal peptide (VIP). The present study examines the effect of third ventricle administration of 192 IgG-saporin immunotoxin on p75N...

journal_title：Neuroreport

authors： Moga MM

更新日期：1998-10-05 00:00:00

abstract：:Sensory information from the genitourinary tract is transmitted to perineal muscle reflex circuits in the spinal cord and to the medullary reticular formation (MRF). This is the first report of a functional descending connection between neurons in the MRF and sensory inputs of the pudendal motoneuron reflex circuitry....

journal_title：Neuroreport

authors： Johnson RD,Hubscher CH

更新日期：1998-01-26 00:00:00

abstract：:Thyroid hormones, which play an important role in the development and regeneration of the nervous system, require the presence of specific nuclear T3 receptors (NT3R). In this study we provide evidence that NT3R expression by Schwann cells was up-regulated in response to a loss of axonal contact in vitro and in vivo. ...

journal_title：Neuroreport

authors： Walter IB

更新日期：1993-11-18 00:00:00

abstract：:Latest reports suggest the involvement of insulin in modulating memory. A few published in-vitro studies favor the antidementia effect of insulin. Thus, the present study aimed to evaluate the prophylactic role of insulin and its combination with glucose and its possible mechanism(s) in an aluminum chloride (AlCl3)-in...

journal_title：Neuroreport

authors： Nampoothiri M,Kumar N,Venkata Ramalingayya G,Gopalan Kutty N,Krishnadas N,Mallikarjuna Rao C

更新日期：2017-06-14 00:00:00

abstract：:Previous studies have demonstrated induced gamma-band activity (GBA) over posterior temporo-parietal and inferior frontal cortex during auditory spatial vs pattern mismatch processing, respectively. Here we investigated magnetoencephalographic oscillatory responses during an active auditory pattern oddball task. Fourt...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W

更新日期：2004-10-05 00:00:00

abstract：:We examined effects of trial averaging upon spatial extent, spatial topography, and temporal properties of fMRI activation. Two subjects participated in an event-related visual stimulation design. There was an exponential relation between number of trials and spatial extent, such that additional trials identified, on ...

journal_title：Neuroreport

authors： Huettel SA,McCarthy G

更新日期：2001-08-08 00:00:00

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:Sensory funneling of liminal multiple-point air-puff stimulation on the skin was evaluated by measuring somatosensory evoked potentials (SEPs), reaction time (RT) and subjective detection threshold. Single-point air-puffs at the threshold intensity, and 2-point and 3-point air-puffs (10 mm apart) of the same intensity...

journal_title：Neuroreport

authors： Hashimoto I,Yoshikawa K,Kimura T

更新日期：1999-10-19 00:00:00

abstract：:In mammals, the thalamic intergeniculate leaflet (IGL) conveys behavioral (non-photic) phase-resetting information to the circadian clock of the suprachiasmatic nucleus. Here we report a 24 h fluctuation in in vivo serotonin release in the hamster IGL region, peaking at night. Novel wheel exposure at midday, a stimulu...

journal_title：Neuroreport

authors： Grossman GH,Farnbauch L,Glass JD

更新日期：2004-01-19 00:00:00

abstract：:The amounts of three adenylyl cyclase (AC) subtypes in membranes from brain obtained post-mortem from patients with dementia of Alzheimer type (DAT) and controls were studied by Western blotting using polyclonal antibodies. AC subtypes were characterized by preabsorption by complementary peptides, species difference, ...

journal_title：Neuroreport

authors： Yamamoto M,Ozawa H,Saito T,Frölich L,Riederer P,Takahata N

更新日期：1996-11-25 00:00:00

abstract：:Although beta-amyloid precursor protein (APP) has been suggested to play a role in neuronal survival and plasticity, the mRNA expression of APP has not been studied in terms of neuronal activity. In cultures of mouse cerebellar granule cells, we found that the levels of APP mRNA increased when a high concentration of ...

journal_title：Neuroreport

authors： Tabuchi A,Ishii A,Fukuchi M,Kobayashi S,Suzuki T,Tsuda M

更新日期：2004-06-07 00:00:00

abstract：:Voltage-dependent outward currents were examined in CA1 neurones by whole-cell recording in slices. Nine cells were recorded with the 'standard' internal solution (KMeSO4, HEPES, EGTA, CaCl2, and MgCl2) and held a potential (-54 +/- 3 mV) at which there was no significant outward current. Cromakalim (CROM, 100 microM)...

journal_title：Neuroreport

authors： Erdemli G,Krnjević K

更新日期：1994-06-27 00:00:00

abstract：:Recently, we have demonstrated that bone marrow stem cells can differentiate into retinal nerve cells. In the present study, we show a new and efficient strategy for transplanting bone marrow stem cells into the retina. When bone marrow stem cells were injected into the vitreous cavity of untreated eyes, only very few...

journal_title：Neuroreport

authors： Minamino K,Adachi Y,Yamada H,Higuchi A,Suzuki Y,Iwasaki M,Nakano K,Koike Y,Mukaide H,Kiriyama N,Shigematsu A,Matsumura M,Ikehara S

更新日期：2005-08-22 00:00:00

abstract：:In a three-stimulus oddball task, the amplitude of P3a elicited by deviant stimuli increases with an increase in the difficulty of discriminating between standard and target stimuli (i.e. task-difficulty effect on P3a), indicating that attentional capture by deviant stimuli is enhanced with an increase in task difficu...

journal_title：Neuroreport

authors： Sugimoto F,Kimura M,Takeda Y,Katayama J

更新日期：2017-08-16 00:00:00

abstract：:Predicting neuron death or survival after axonal injury is important in neurotrauma research. We now used in vivo confocal neuroimaging microscopy to repeatedly visualize retinal ganglion cells after optic nerve crush and studied their morphological alterations and ultimate fate. An intracollicular injection of a retr...

journal_title：Neuroreport

authors： Rousseau V,Engelmann R,Sabel BA

更新日期：1999-11-08 00:00:00

abstract：:Using in situ hybridization histochemistry and immunocytochemistry the induction of immediate early genes (IEGs) was studied in the rat superior cervical ganglion (SCG) after deafferentation, axotomy and sialectomy (removal of the submandibular gland). Control SCGs showed very low levels of IEGs, whereby Fos proteins ...

journal_title：Neuroreport

authors： Koistinaho J,Pelto-Huikko M,Sagar SM,Dagerlind A,Roivainen R,Hökfelt T

更新日期：1993-01-01 00:00:00

abstract：:In the adult rat hippocampal formation, neurogenesis occurs in the dentate gyrus subgranular zone (SGZ). We used laser capture microdissection and an antidepressant-related genes microarray to analyze gene expression profiles of cells from the SGZ and from the outermost granule cell layer. Of the differentially expres...

journal_title：Neuroreport

authors： Yamada M,Takahashi K,Ukai W,Hashimoto E,Saito T,Yamada M

更新日期：2010-01-27 00:00:00

abstract：:Oscillatory activity is a ubiquitous property of brain signals, and yet relatively few studies have investigated how the phase of such ongoing oscillations affects our cognition. One of the main findings in this field is that the phase of electroencephalography (EEG) in the alpha band can affect perception of millisec...

journal_title：Neuroreport

authors： Jalali A,Tata MS,Gruber AJ,Luczak A

更新日期：2019-04-10 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:The efficacy and safety of thrombolysis with different dose regimens of recombinant tissue plasminogen activator (rt-PA) and its combination with aspirin was tested in an embolic stroke model. In rats the carotid territory was embolized with a single clot formed in a polyethylene tube and washed with saline. Fifteen m...

journal_title：Neuroreport

authors： Overgaard K,Sereghy T,Pedersen H,Boysen G

更新日期：1992-10-01 00:00:00

abstract：:Since the first identification of an association between mutations in the connexin26 (Cx26) gene and autosomal recessive non-syndromic deafness it has been shown that several mutations in this gene cause recessive, sporadic, and dominant non-syndromic deafness. Three novel mutations in the Cx26 gene were identified in...

journal_title：Neuroreport

authors： Fuse Y,Doi K,Hasegawa T,Sugii A,Hibino H,Kubo T

更新日期：1999-06-23 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:We compared various measures of visual-vestibular interaction in subjects with insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM), as well as non-diabetic controls. Subjects with IDDM exhibited significantly greater postural sway than controls on those conditions in the Clini...

journal_title：Neuroreport

authors： Darlington CL,Erasmus J,Nicholson M,King J,Smith PF

更新日期：2000-02-28 00:00:00

abstract：:We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...

journal_title：Neuroreport

authors： Gutz L,Küpper C,Renneberg B,Niedeggen M

更新日期：2011-06-22 00:00:00

abstract：:Transcranial magnetic stimulation (TMS) was applied over the frontal eye field (FEF) and the supplementary eye field (SEF) regions before execution of the first saccade in a double step task. When applied over the FEF, stimulation increased the percentage error in amplitude of the contralateral second saccade as compa...

journal_title：Neuroreport

authors： Tobler PN,Müri RM

更新日期：2002-02-11 00:00:00

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for serotonin type 6 receptors (5HT6). We tested the hypothesis that clinical response to clozapine in patients refractory to typical antipsychotic treatment is related to the genetic variant (C267T) of the 5HT6 receptors. Ninety-nine schizophreni...

journal_title：Neuroreport

authors： Yu YW,Tsai SJ,Lin CH,Hsu CP,Yang KH,Hong CJ

更新日期：1999-04-26 00:00:00

abstract：:We have recently characterized a form of ex vivo depotentiation (depotentiationex vivo), which correlates tightly with fear extinction, at thalamic input synapses onto the lateral amygdala. Here, we examined the effects of learning-attenuating drugs, reported to impair fear extinction when microinjected into the basol...

journal_title：Neuroreport

authors： Kim J,Park S,Lee S,Choi S

更新日期：2009-03-25 00:00:00

abstract：:Slices of rat cingulate cortex, when incubated in magnesium-free medium, produce spontaneous epileptiform spikes. Here it is demonstrated that the metabotropic glutamate receptor (mGluR) agonists +/- trans-1-amino-cyclopentane-1,3-dicarboxylic acid (+/- Trans-ACPD), IS3R-ACPD and quisqualic acid (quis) can reduce the ...

journal_title：Neuroreport

authors： Sheardown MJ

更新日期：1992-10-01 00:00:00

abstract：:Whereas facial emotion recognition protocols have shown that each discrete emotion has a specific time course of brain activation, there is no electrophysiological evidence to support these findings for emotional induction by complex pictures. Our objective was to specify the differences between the time courses of br...

journal_title：Neuroreport

authors： Hot P,Sequeira H

更新日期：2013-11-13 00:00:00

abstract：:The neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT) and transported into synaptic vesicles by the vesicular acetylcholine transporter (VAChT). Recently it has been reported that the entire coding region of VAChT mRNA is located in the first intron of the ChAT gene. In this study, ChAT...

journal_title：Neuroreport

authors： Misawa H,Takahashi R,Deguchi T

更新日期：1995-05-09 00:00:00