Birth insult and stress interact to alter dopamine transporter binding in rat brain.

abstract：:Antisera were produced against synthetic peptides predicted from the recent cloning of a delta opioid receptor, DOR-1. Confocal microscopic examination of immunostained spinal cord sections revealed that DOR-1 immunoreactive (-ir) nerve fibers and terminals form a moderately dense plexus within the superficial dorsal ...

journal_title：Neuroreport

authors： Dado RJ,Law PY,Loh HH,Elde R

更新日期：1993-12-13 00:00:00

abstract：:It is assumed that in esotropic cats the behavioural suppression of the nasal field reflects inhibition of the input conveyed through the temporal retinal afferents of the strabismic eye. We hypothesized that inhibition underlying the field defect might be actively operated by interocular competitive mechanisms. If so...

journal_title：Neuroreport

authors： Di Stefano M,Gargini C

更新日期：1995-06-19 00:00:00

abstract：:The ATP-gated cation channel P2X3 is expressed selectively by rat sensory neurones, and may play a role in nociception by binding ATP released from damaged or inflamed tissues. However, the distribution of this channel in human sensory neurons is not known. Using a specific antibody, we have demonstrated intense P2X3 ...

journal_title：Neuroreport

authors： Yiangou Y,Facer P,Birch R,Sangameswaran L,Eglen R,Anand P

更新日期：2000-04-07 00:00:00

abstract：:Papaverine is a non-specific vasodilatory drug, which was found to unexpectedly cause opening of the blood-brain barrier (BBB). We studied the expression of two endothelial cell related markers, endothelial barrier antigen (EBA) as a marker of BBB intactness, and matrix metalloproteinase-9 (MMP-9), an extracellular ma...

journal_title：Neuroreport

authors： Bhattacharjee AK,Kondoh T,Ikeda M,Kohmura E

更新日期：2002-12-03 00:00:00

abstract：:The effect of systemic treatment with 1-aminocyclopro-panecarboxylic acid (ACPC), a partial agonist at the glycine site of the NMDA receptor, on convulsions and neurodegeneration induced by intrahippocampal injection of NMDA was investigated in mice. Five days after intrahippocampal NMDA infusion, 80-100% pyramidal ce...

journal_title：Neuroreport

authors： Zapata A,Capdevila JL,Viu E,Trullas R

更新日期：1996-01-31 00:00:00

abstract：:Diffusion tensor imaging was used to measure regional differences in brain white matter microstructure (intravoxel coherence) and macrostructure (intervoxel coherence) and age-related differences between men and women. Neuropsychiatrically healthy men and women, spanning the adult age range, showed the same pattern of...

journal_title：Neuroreport

authors： Sullivan EV,Adalsteinsson E,Hedehus M,Ju C,Moseley M,Lim KO,Pfefferbaum A

更新日期：2001-01-22 00:00:00

abstract：:Axotomy-induced death of corticospinal neurons (CSN) is prevented by intracotrical infusions of BDNF or NT-3 within the first week after axotomy. The present study examined whether this represents merely a delay of CSN death or whether BDNF and NT-3 can promote long-term survival of these neurons in vivo. The neurotro...

journal_title：Neuroreport

authors： Hammond EN,Tetzlaff W,Mestres P,Giehl KM

更新日期：1999-08-20 00:00:00

abstract：:The neural foundation of age-related declines in prospective memory was explored using event-related brain potentials (ERPs). Consistent with previous research, a decline in the efficiency of prospective memory was observed in older adults that reflected a decrease in veridical prospective responses and an increase in...

journal_title：Neuroreport

authors： West R,Covell E

更新日期：2001-09-17 00:00:00

abstract：:This study aimed to investigate effects of observing the own body being touched on the functional topography of the somatosensory homunculus. We used neuromagnetic source imaging to map the topography in primary somatosensory cortex (SI) while manipulating the visibility of a touched hand. Participants were either abl...

journal_title：Neuroreport

authors： Schaefer M,Heinze HJ,Rotte M

更新日期：2008-06-11 00:00:00

abstract：:The role of the medial septum in suppressing paradoxical sleep and promoting slow wave sleep was suggested on the basis of neurotoxic lesion studies. However, these conclusions need to be substantiated with further experiments, including chemical stimulation studies. In this report, the medial septum was stimulated in...

journal_title：Neuroreport

authors： Mukherjee D,Kaushik MK,Jaryal AK,Kumar VM,Mallick HN

更新日期：2012-05-09 00:00:00

abstract：:Auditory evoked magnetic fields were recorded with a 24-SQUID magnetometer on a patient with a vascular lesion in the right auditory cortex and its vicinity. The contralateral transient 100 ms response (N100m) was absent over the damaged side, with no recovery within 16 months. Responses were normal over the healthy s...

journal_title：Neuroreport

authors： Mäkelä JP,Hari R

更新日期：1992-01-01 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP-22) gene which results in abnormal myelination of the peripheral nervous system. However, the clinical symptoms observed in the mutant suggest abnormalities in the central nervous system. Using the Northern blot te...

journal_title：Neuroreport

authors： Bascles L,Bonnet J,Garbay B

更新日期：1994-06-02 00:00:00

abstract：:The present investigation provide evidences from a non-human primate model that naturally occurring menopause predicts a prominent signature of age-related cognitive decline. Young and aged rhesus monkeys were tested on a delayed response (DR) task known to the sensitive to aging, and reproductive status was evaluated...

journal_title：Neuroreport

authors： Roberts JA,Gilardi KV,Lasley B,Rapp PR

更新日期：1997-05-27 00:00:00

abstract：:Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

journal_title：Neuroreport

authors： Hall GB,Witelson SF,Szechtman H,Nahmias C

更新日期：2004-02-09 00:00:00

abstract：:In the present study, changes in the cytokine system (IL-1 beta, IL-2, IL-3, IL-6 and TNF alpha) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNF alpha, a decrease in that of IL-2 and of IL-3 with no change in IL-1 beta and in IL-6 secretion lev...

journal_title：Neuroreport

authors： Mittwoch-Jaffe T,Shalit F,Srendi B,Yehuda S

更新日期：1995-03-27 00:00:00

abstract：:The regulation of glucocorticoid receptors and nuclear factor kappaB was evaluated in the spiral ganglion neurons after 4 h of restraint stress in the mouse cochlea. Immediately after restraint stress, glucocorticoid receptor protein expression was not altered in spiral ganglion neurons even though both the plasma cor...

journal_title：Neuroreport

authors： Tahera Y,Meltser I,Johansson P,Canlon B

更新日期：2006-06-26 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00

abstract：:The present study aims to study sequential alterations occurring in both dopaminergic neurons and microglia in substantia nigra (SN) following intrastriatal injection of 1-methyl-4-phenylpridium ion (MPP+) in rats. Heme oxygenase-1 (HO-1), a marker of oxidative stress, first appeared in dopaminergic neurons in SN at 1...

journal_title：Neuroreport

authors： Miwa H,Kubo T,Morita S,Nakanishi I,Kondo T

更新日期：2004-04-29 00:00:00

abstract：:Neuronal activity may lead to long lasting changes in cell phenotype through induction of genes such as c-fos which encode transcriptional regulatory factors. Odor-activated olfactory bulb cells exhibit increases in c-fos mRNA expression. The present study examined whether odor stimulation of awake rats also leads to ...

journal_title：Neuroreport

authors： Guthrie KM,Gall CM

更新日期：1995-11-13 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis...

journal_title：Neuroreport

authors： Hadjikhani N,Chabris CF,Joseph RM,Clark J,McGrath L,Aharon I,Feczko E,Tager-Flusberg H,Harris GJ

更新日期：2004-02-09 00:00:00

abstract：:AMPA-preferring glutamate receptor genes gluR1-4 undergo alternative splicing into flip and flop mRNA isoforms. In the rodent hippocampus, gluR1 and gluR2 isoforms are differentially expressed. We have studied their distribution in human hippocampus. As in the rat, flop isoforms predominate over flip in dentate gyrus,...

journal_title：Neuroreport

authors： Eastwood SL,Burnet PW,Beckwith J,Kerwin RW,Harrison PJ

更新日期：1994-06-27 00:00:00

abstract：:An important issue regarding the neural basis of major depression is whether the functional brain changes associated with the affect disturbance seen in this syndrome are similar to those that accompany transient sadness in normal subjects. To address this question, we carried out an fMRI study using an emotional acti...

journal_title：Neuroreport

authors： Beauregard M,Leroux JM,Bergman S,Arzoumanian Y,Beaudoin G,Bourgouin P,Stip E

更新日期：1998-10-05 00:00:00

abstract：:Chronic ethanol exposure is known to alter the polyphosphoinositide (poly-PI) signaling pathway, although the exact sight of regulation is not well understood. In this study, C57B1/6J mice were given a control or an ethanol (6 g kg-1 body wt) liquid diet by gastric intubation daily for 4 weeks. Examination of levels o...

journal_title：Neuroreport

authors： Simonyi A,Zhang JP,Sun AY,Sun GY

更新日期：1996-09-02 00:00:00

abstract：:Myelin basic proteins (MBPs) have been shown to be ADP-ribosylated in-vitro by cholera toxin in the presence of NAD. Since acid-soluble extracts of brain contain other proteins in the 14-32 kD range (such as histones) in addition to MBP's, the identification of the ADP-ribosylated proteins was uncertain. To determine ...

journal_title：Neuroreport

authors： Boulias C,Moscarello MA

更新日期：1990-11-01 00:00:00

abstract：:Propofol is widely used for induction and maintenance of anaesthesia, which causes a rapid loss of consciousness. So far the mechanisms underlying the effect of propofol are still largely unknown. Here, we found that microinjection of propofol in the lateral hypothalamus caused a significant decrease in wakefulness an...

journal_title：Neuroreport

authors： Shi Y,Xiao D,Dai L,Si Y,Fang Q,Wei X

更新日期：2019-10-09 00:00:00

abstract：:Vectors based on lentiviruses are opening up new approaches for the treatment of neurodegenerative diseases. Currently, the equine infectious anaemia virus (EIAV) vector is one of the most attractive gene delivery systems with respect to neuronal tropism. The aim was to validate EIAV-lentiviral vectors as a gene deliv...

journal_title：Neuroreport

authors： Azzouz M,Ralph S,Wong LF,Day D,Askham Z,Barber RD,Mitrophanous KA,Kingsman SM,Mazarakis ND

更新日期：2004-04-29 00:00:00

abstract：:The tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 is expressed only in nociceptive sensory neurons. This channel has been proposed to contribute significantly to the sensitization of primary sensory neurons after injury. We have studied the nociceptive behaviours of mice carrying a null mutation in the N...

journal_title：Neuroreport

authors： Kerr BJ,Souslova V,McMahon SB,Wood JN

更新日期：2001-10-08 00:00:00

abstract：:Segmental ligation of spinal nerves in the rat induces a long-lasting hyperalgesia and allodynia that mimicks neuropathic conditions in humans. In the present study we attempted to determine whether supraspinal NMDA receptors contribute to the induction of the long-lasting hypersensitivity to noxious and innocuous mec...

journal_title：Neuroreport

authors： Wei H,Pertovaara A

更新日期：1999-09-29 00:00:00

abstract：:Two developmental disorders, autism and Williams syndrome, are both commonly described as having difficulties in integrating perceptual features, i.e. binding spatially separate elements into a whole. It is already known that healthy adults and infants display electroencephalographic (EEG) gamma-band bursts (around 40...

journal_title：Neuroreport

authors： Grice SJ,Spratling MW,Karmiloff-Smith A,Halit H,Csibra G,de Haan M,Johnson MH

更新日期：2001-08-28 00:00:00

abstract：:DCC is a member of the immunoglobulin superfamily of cell adhesion molecules, whose role in the function of the adult nervous system is unknown. DCC mRNA expression was studied in adult rat dorsal hippocampal sections using in situ hybridization histochemistry. High levels of DCC transcript were detected in hippocampu...

journal_title：Neuroreport

authors： Volenec A,Bhogal RK,Moorman JM,Leslie RA,Flanigan TP

更新日期：1997-09-08 00:00:00