MK-801, an NMDA receptor antagonist, in the rostroventromedial medulla attenuates development of neuropathic symptoms in the rat.

abstract：:Intra-ischemic hypothermia is known to protect neurons against ischemic injury. Microglial cells have been shown to become activated following ischemia and are speculated to play significant roles in the evolution of ischemic neuronal injury. In this study, we examined the effect of intra-ischemic hypothermia on the m...

journal_title：Neuroreport

authors： Kumar K,Evans AT

更新日期：1997-03-03 00:00:00

abstract：:Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

journal_title：Neuroreport

authors： Kempster S,Collins ME,Edington N

更新日期：2004-10-05 00:00:00

abstract：:Effects of glutamate on synaptic transmission in the submucosal plexus of guinea-pig small intestine were studied with intracellular electrophysiological recording methods. Glutamate suppressed stimulus-evoked slow excitatory postsynaptic potentials (EPSPs) and increased the amplitude of slow inhibitory postsynaptic p...

journal_title：Neuroreport

authors： Ren J,Hu HZ,Liu S,Xia Y,Wood JD

更新日期：1999-09-29 00:00:00

abstract：:Modulation of the soleus H-reflex following galvanic vestibular stimulation (GVS) has been used to evaluate vestibulospinal tract function. It is not known whether this modulation is because of vestibular stimulation and/or cutaneous stimulation, and the suitable stimulating intensity of GVS for the modulation is not ...

journal_title：Neuroreport

authors： Okada Y,Shiozaki T,Nakamura J,Azumi Y,Inazato M,Ono M,Kondo H,Sugitani M,Matsugi A

更新日期：2018-09-05 00:00:00

abstract：:The role of dopamine D1A receptors in mediating amphetamine-induced sensitization was investigated using the D1A-deficient mouse. During the drug pre-exposure phase, D1A-deficient and control mice were injected for five consecutive days with saline or amphetamine (2 mg/kg, i.p.). Locomotor activity was measured on the...

journal_title：Neuroreport

authors： Crawford CA,Drago J,Watson JB,Levine MS

更新日期：1997-07-28 00:00:00

abstract：:The possible role of endogenous cholinergic innervation in hippocampal plasticity is controversial. We studied the role of acetylcholine (ACh) in short- and long-term potentiation (STP and LTP), using the cholinergic neurotoxin 192 IgG-saporin. It was still possible to induce STP the LTP in the CA1 field following com...

journal_title：Neuroreport

authors： Jouvenceau A,Billard JM,Lamour Y,Dutar P

更新日期：1996-03-22 00:00:00

abstract：:Evidence of glutamatergic dysfunction in schizophrenia associated with the N-methyl-D-aspartate receptor has historically demonstrated changes primarily attributable to neurons. We propose an astrocytic component to N-methyl-D-aspartate receptor dysfunction in this illness. We studied the expression of serine racemase...

journal_title：Neuroreport

authors： Steffek AE,Haroutunian V,Meador-Woodruff JH

更新日期：2006-07-31 00:00:00

abstract：:The interaction between the Ca(2+)-activated K+ currents (IK(Ca)) induced by acetylcholine (ACh), 1-aminocyclopentane-1S,3R-dicarboxylic acid (1S,3R)-ACPD) and caffeine in rat hippocampal CA1 neurones was investigated to examine the functional independence between IP3- and Ca(2+)-sensitive Ca2+ stores. Pretreatment wi...

journal_title：Neuroreport

authors： Imanishi T,Yamanaka H,Rhee JS,Akaike N

更新日期：1996-05-31 00:00:00

abstract：:Whereas facial emotion recognition protocols have shown that each discrete emotion has a specific time course of brain activation, there is no electrophysiological evidence to support these findings for emotional induction by complex pictures. Our objective was to specify the differences between the time courses of br...

journal_title：Neuroreport

authors： Hot P,Sequeira H

更新日期：2013-11-13 00:00:00

abstract：:The rat suprachiasmatic (SCN) contains a dense plexus of low-affinity p75 neurotrophin receptor (p75NTR)-immunoreactivity. In some SCN neurons, p75NTR is co-localized with vasoactive intestinal peptide (VIP). The present study examines the effect of third ventricle administration of 192 IgG-saporin immunotoxin on p75N...

journal_title：Neuroreport

authors： Moga MM

更新日期：1998-10-05 00:00:00

abstract：:BC200 is a long noncoding RNA expressed at high levels in the Alzheimer's disease (AD), and blocking of BC200 by siRNA is assumed to be an effective method for various disease therapy. We have established an AD cell model overexpressing amyloid β-peptide (Aβ)1-42 to observe the effects of BC200 on the cell viability a...

journal_title：Neuroreport

authors： Li H,Zheng L,Jiang A,Mo Y,Gong Q

更新日期：2018-09-05 00:00:00

abstract：:The cellular distribution of the rat metabotropic glutamate receptor type 4 (mGluR4) was examined in the adult rat cerebral cortex and hippocampus. Antibodies were raised against amino acid residues located in the extracellular amino terminal domain that is common to both the mGluR4a and mGluR4b splice variants, and u...

journal_title：Neuroreport

authors： Phillips T,Makoff A,Brown S,Rees S,Emson P

更新日期：1997-10-20 00:00:00

abstract：:The study was conducted to investigate the effect of serotonin depletion on nitric oxide-induced meningeal vascular response and cerebrovascular nociception. Nitroglycerin was infused i.v. to control and serotonin-depleted rats. Pial circulation was monitored by intravital fluorescent videomicroscopy and Fos immunorea...

journal_title：Neuroreport

authors： Srikiatkhachorn A,Anuntasethakul T,Phansuwan-Pujito P,Patumraj S,Kasantikul V

更新日期：2001-04-17 00:00:00

abstract：:Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural...

journal_title：Neuroreport

authors： Kéri S,Gulyás B

更新日期：2003-06-11 00:00:00

abstract：:Reorganization of motor execution and imagination networks was studied in six patients with unilateral dystonia secondary to a subcortical stroke and compared with seven control subjects using fMRI. Patients performed imagined and real auditory-cued hand movements. Movements of the dystonic hand resulted in overactivi...

journal_title：Neuroreport

authors： Lehéricy S,Gerardin E,Poline JB,Meunier S,Van de Moortele PF,Le Bihan D,Vidailhet M

更新日期：2004-08-26 00:00:00

abstract：:Monoamine oxidase A (MAOA) enzymatically degrades biogenic amines such as norepinephrine, dopamine, and serotonin, and plays a key role in the regulation of their neurotransmission. Allelic variations at the MAOA locus have been implicated in the neurobiology of aggression and impulsivity. We investigated the possible...

journal_title：Neuroreport

authors： Lee BT,Ham BJ

更新日期：2008-03-26 00:00:00

abstract：:Lithium treatment lengthens the period of circadian rhythms in most organisms. In the present study, we tested whether lithium acts directly on the mammalian suprachiasmatic nucleus (SCN) to lengthen rhythms of individual neurons. Lithium increased the circadian period of firing rate rhythms of cultured SCN neurons in...

journal_title：Neuroreport

authors： Abe M,Herzog ED,Block GD

更新日期：2000-09-28 00:00:00

abstract：:The aim of this study was to investigate whether the DNA methylation pattern within the alpha synuclein promoter region is altered in intoxicated and early abstinence patients with alcoholism undergoing alcohol withdrawal. We observed a significant increase of the alpha synuclein promoter DNA methylation in patients w...

journal_title：Neuroreport

authors： Bönsch D,Lenz B,Kornhuber J,Bleich S

更新日期：2005-02-08 00:00:00

abstract：:The aim of the present study was to determine if both inactivating and non-inactivating potassium currents occur in skeletal muscle cells at early times in culture. Whole cell current was recorded from embryonic muscle cells within 4-10 h of plating. We found that in the cells which had an outward current, half had a ...

journal_title：Neuroreport

authors： Moody-Corbett F,Gilbert R

更新日期：1992-04-01 00:00:00

abstract：:The NMa and NMb isoforms of cytochrome P450 enzymes are expressed in three nasal chemosensory organs: the olfactory, septal and vomeronasal mucosae. The NMa isoform is widely distributed throughout the nasal mucosa whereas the NMb isoform is present primarily in the chemosensory mucosae. The localization of cytochrome...

journal_title：Neuroreport

authors： Chen Y,Getchell ML,Ding X,Getchell TV

更新日期：1992-09-01 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP-22) gene which results in abnormal myelination of the peripheral nervous system. However, the clinical symptoms observed in the mutant suggest abnormalities in the central nervous system. Using the Northern blot te...

journal_title：Neuroreport

authors： Bascles L,Bonnet J,Garbay B

更新日期：1994-06-02 00:00:00

abstract：:ERPs were recorded from subjects performing semantic and rhyme matching tasks using either spoken words, printed words or pictures as stimuli. Mismatches enhanced N400 (in the semantic task) and N450 (in the rhyme task). Onset and peak latencies were shorter for N450 than for N400 with spoken words; this relationship ...

journal_title：Neuroreport

authors： Perez-Abalo MC,Rodriguez R,Bobes MA,Gutierrez J,Valdes-Sosa M

更新日期：1994-10-27 00:00:00

abstract：:To determine whether physical match between studied and tested items influences blood flow increases in the hippocampal formation associated with recognition memory, positron emission tomography (PET) was used to measure changes in regional cerebral blood flow while healthy volunteers made old/new judgements about lin...

journal_title：Neuroreport

authors： Schacter DL,Uecker A,Reiman E,Yun LS,Bandy D,Chen K,Cooper LA,Curran T

更新日期：1997-12-22 00:00:00

abstract：:The aim of the present study was to examine the effects of nicotinamide, a co-factor in the electron transport chain, on the relationship between methamphetamine (MA)-induced striatal dopamine (DA) depletion and energy metabolism change. Four injections of MA (10 mg/kg, i.p.) at 2 h intervals resulted in decreases of ...

journal_title：Neuroreport

authors： Huang NK,Wan FJ,Tseng CJ,Tung CS

更新日期：1997-05-27 00:00:00

abstract：:The anxiolytic-like potential of anpirtoline was assessed in a mouse light/dark aversion test. Anpirtoline (1.0 ng kg(-1)-1.0 micrograms kg-1 i.p.) reduced the aversive responding of mice. This was detected as an increase in the latency to locate the non-aversive compartment and by decreases in the percentage of the t...

journal_title：Neuroreport

authors： Metzenauer P,Barnes NM,Costall B,Gozlan H,Hamon M,Kelly ME,Murphy DA,Naylor RJ

更新日期：1992-06-01 00:00:00

abstract：:Using a system capable of relatively localized and rapidrate transcranial magnetic stimulation (rTMS), evoked trains of complex spikes were studied in rodent auditory cortex. Low rate rTMS from 1 to 10Hz produced a frequency-dependent increase in spike rate. Iterations of rTMS resulted in long-term potentiation (LTP)-...

journal_title：Neuroreport

authors： Wang H,Wang X,Scheich H

更新日期：1996-01-31 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:TA20 cDNA was previously cloned as a neurite outgrowth factor from a hybridoma of mouse and rat cells, NG108-15. To clarify the detailed function and tissue distribution of this gene, homologous sequences of rat and mouse were identified. The cloned sequences had no homology with known genes, and was designated as spr...

journal_title：Neuroreport

authors： Tohda C,Jacobowitz DM

更新日期：1999-07-13 00:00:00

abstract：:We examined the effect of stimulus interruption on dual component field EPSPs in the hippocampal CA1 region. Resuming test stimulation at 0.1 Hz after 10-60 min silent periods led to an increase of the response followed by a decline, involving AMPA and NMDA components to a similar extent. Similar changes were seen whe...

journal_title：Neuroreport

authors： Niu YP,Xiao MY,Karpefors M,Wigström H

更新日期：1999-04-06 00:00:00

abstract：:Microglial activation plays a critical role in spinal cord ischemic reperfusion injury. Spinal cord stimulation preconditioning and postconditioning has shown spinal cord protection in ischemic reperfusion injury in animal studies. However, whether spinal cord stimulation could reduce microglial activation is still un...

journal_title：Neuroreport

authors： Dong X,Li H,Lu J,Yang Y,Jing H,Cheng Y,Jin M,Cheng W

更新日期：2018-09-26 00:00:00