Effect of serotonin depletion on nitric oxide induced cerebrovascular nociceptive response.

Abstract:

:The study was conducted to investigate the effect of serotonin depletion on nitric oxide-induced meningeal vascular response and cerebrovascular nociception. Nitroglycerin was infused i.v. to control and serotonin-depleted rats. Pial circulation was monitored by intravital fluorescent videomicroscopy and Fos immunoreactivity trigeminal nucleus caudalis neurons was used as an indicator for the cerebrovascular nociception. The results showed that the degree of nitric oxide-induced pial microvascular dilatation was significantly greater in the serotonin-depleted group than the control. The number of nitric oxide-evoked Fos-immunoreactive cells between the two groups remained comparable. The results suggest that though depletion of serotonin can facilitate the vascular response to nitric oxide it does not alter the nitric oxide-induced craniovascular nociceptive response.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Srikiatkhachorn A,Anuntasethakul T,Phansuwan-Pujito P,Patumraj S,Kasantikul V

doi

10.1097/00001756-200104170-00021

subject

Has Abstract

pub_date

2001-04-17 00:00:00

pages

967-71

issue

5

eissn

0959-4965

issn

1473-558X

journal_volume

12

pub_type

杂志文章
  • Acute adaptive changes in food intake pattern following olfactory ablation in rats.

    abstract::We determined whether acute compensatory feeding pattern changes after bulbectomy persist on a chronic basis, or whether physiological adaptation occurs to normalize acute changes. Rats were randomized to olfactory bulbectomy or sham operation; all had jugular vein catheterization. Food intake, meal number and size we...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199704140-00023

    authors: Meguid MM,Koseki M,Yang ZJ,Gleason JR,Laviano A

    更新日期:1997-04-14 00:00:00

  • Dopamine modulates striatal response to reward and punishment in patients with Parkinson's disease: a pharmacological challenge fMRI study.

    abstract::It is well established that Parkinson's disease leads to impaired learning from reward and enhanced learning from punishment. The administration of dopaminergic medications reverses this learning pattern. However, few studies have investigated the neural underpinnings of these cognitive processes. In this study, using...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000970

    authors: Argyelan M,Herzallah M,Sako W,DeLucia I,Sarpal D,Vo A,Fitzpatrick T,Moustafa AA,Eidelberg D,Gluck M

    更新日期:2018-05-02 00:00:00

  • Phonological influences on lexicosemantic processing of kanji words.

    abstract::To investigate the phonological influences on the lexicosemantic process with a strong orthographic constraint, we used kanji (morphogram) homophone words and measured, using magnetoencephalography, the neural activities during the silent reading of prime-target pairs. The primes were phonologically the same as or dif...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3282f16ddf

    authors: Wei Q,Ihara A,Hayakawa T,Murata T,Matsumoto E,Fujimaki N

    更新日期:2007-11-19 00:00:00

  • Selective influence of auditory distractors on motor cortex excitability.

    abstract::The diversion of attention from a primary goal by irrelevant events is known as attention capture, and is often followed by a directed action. The hypothesis that corticospinal excitability is modulated by attention capture was tested using transcranial magnetic stimulation. Participants watched a video while sounds w...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32834bc6aa

    authors: Mock JR,Foundas AL,Golob EJ

    更新日期:2011-11-16 00:00:00

  • Corpus callosum: musician and gender effects.

    abstract::Previously we found that musicians have significantly larger anterior corpus callosum (CC). In the current study, we intended to replicate and extend our previous results using a new and larger sample of gender-matched subjects (56 right-handed professional musicians and 56 age- and handedness-matched controls). We fo...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200302100-00009

    authors: Lee DJ,Chen Y,Schlaug G

    更新日期:2003-02-10 00:00:00

  • Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.

    abstract::Mutations in the presenilin genes are involved in the aetiology of the majority of familial early-onset Alzheimer disease (AD) cases. Presenilin 1 (PS1) is proteolytically processed in vivo, resulting in the accumulation of N-terminal approximately 27-28 kDa and C-terminal approximately 18 kDa derivatives. To examine ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199705060-00030

    authors: Hendriks L,Thinakaran G,Harris CL,De Jonghe C,Martin JJ,Sisodia SS,Van Broeckhoven C

    更新日期:1997-05-06 00:00:00

  • Differential distributions of parvalbumin-positive interneurons in the sulci and gyri of the adult ferret cerebral cortex.

    abstract::Although accumulating evidence suggests that there are significant anatomical and histological differences between the sulci and gyri of the cerebral cortex, whether there is a difference in the distribution of interneurons between the two cortical regions remains largely unknown. In this study, we systematically comp...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001309

    authors: Gao JT,Liu Y,Gong D,Feng XM,Wan P,Luo XF,Zhu WH,Hou JC,Lv SJ

    更新日期:2019-10-16 00:00:00

  • The impact of emotional involvement on online service buying decisions: an event-related potentials perspective.

    abstract::When examining a buying process, changes in human brain signals and their event-related potential (ERP) components can be considered a reflection of the consumers' emotions. In this experiment, participants were shown 12 products and related services that were available for purchase. After recording ERP components, we...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000457

    authors: Zhao M,Wang J,Han W

    更新日期:2015-12-02 00:00:00

  • Ulcerogenic cinchophen induces c-Fos expression in CRH-secreting cells in the PVH of rat brain.

    abstract::This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the time of ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199611040-00048

    authors: Jingu H,Miura M

    更新日期:1996-11-04 00:00:00

  • The functional neuroanatomy of major depression: an fMRI study using an emotional activation paradigm.

    abstract::An important issue regarding the neural basis of major depression is whether the functional brain changes associated with the affect disturbance seen in this syndrome are similar to those that accompany transient sadness in normal subjects. To address this question, we carried out an fMRI study using an emotional acti...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199810050-00022

    authors: Beauregard M,Leroux JM,Bergman S,Arzoumanian Y,Beaudoin G,Bourgouin P,Stip E

    更新日期:1998-10-05 00:00:00

  • Activation of acetylcholinesterase by aluminium(III): the relevance of the metal species.

    abstract::The present paper reports how aluminium [Al(III)] at a concentration of 3.7 microM can activate the bovine erythrocytic enzyme acetylcholinesterase (AChE) by about 38% in vitro. This same activating effect was observed on AChE form human as well as from rat erythrocyte ghosts and murine neuroblastoma cells. The intera...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199409080-00023

    authors: Zatta P,Zambenedetti P,Bruna V,Filippi B

    更新日期:1994-09-08 00:00:00

  • Distinctive neuronal organization of the olfactory bulb of the laboratory shrew.

    abstract::The organization of the main olfactory bulb of an insectivore, the laboratory shrew (Suncus murinus), was studied morphologically. We found particular small spherical regions, nidi, at the border between the glomerular and external plexiform layer (EPL), which were intensely GAD positive, 30-60 microm in diameter, and...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199902050-00012

    authors: Kosaka K,Kosaka T

    更新日期:1999-02-05 00:00:00

  • Involvement of CRF2 receptor in the brain regions in restraint-induced anorexia.

    abstract::We have reported that corticotropin-releasing factor (CRF) receptor subtypes, CRF1 and CRF2, are involved in stress-induced anorexia. To clarify in which brain regions the CRF receptor is involved in mediating stress-induced anorexia, we examined the effect of microinjecting CRF1-selective or CRF2-selective antagonist...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283487467

    authors: Ohata H,Shibasaki T

    更新日期:2011-07-13 00:00:00

  • Evidence that matrix recognition contributes to stabilization but not induction of LTP.

    abstract::Slices of hippocampus were incubated with Arg-Gly-Asp (RGD) peptides known to block members of the integrin class of matrix receptors. Though the peptides caused no detectable difference in the amount of long-term potentiation (LTP) expressed in the CA1 field 1-2 min after induction with high frequency stimulation, th...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199108000-00013

    authors: Xiao P,Bahr BA,Staubli U,Vanderklish PW,Lynch G

    更新日期:1991-08-01 00:00:00

  • Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB-dependent inflammatory responses following experimental traumatic brain injury in rats.

    abstract::Previous studies have shown that isosteviol sodium (STVNa) protects against permanent cerebral ischemia injury by inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-mediated inflammatory responses. Overwhelming evidence shows that toll-like receptors (TLRs) are the upstream regula...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001033

    authors: Zan J,Zhang H,Lu MY,Beng HM,Zhong KL,Sun XO,Tan W

    更新日期:2018-07-04 00:00:00

  • Mutation screening in exons 3 and 4 of alpha-synuclein in sporadic Parkinson's and sporadic and familial dementia with Lewy bodies cases.

    abstract::Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the alpha-synuclein gene were linked to familial Parkinson's Disease (PD). We decided to investigate if these and any other mutations in exons 3 and 4 of the alpha-synuclein gene could be detect...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199812010-00029

    authors: El-Agnaf OM,Curran MD,Wallace A,Middleton D,Murgatroyd C,Curtis A,Perry R,Jaros E

    更新日期:1998-12-01 00:00:00

  • Combined event-related fMRI and EEG evidence for temporal-parietal cortex activation during target detection.

    abstract::Target detection is the process of bringing a salient stimulus into conscious awareness. Target detection evokes a prominent event-related potential (ERP) component (P3) in the electroencephalogram (EEG). We combined the high spatial resolution of functional magnetic resonance imaging (fMRI) with the high temporal res...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00001756-199709290-00007

    authors: Menon V,Ford JM,Lim KO,Glover GH,Pfefferbaum A

    更新日期:1997-09-29 00:00:00

  • Electrophysiological evidence for a two-stage process underlying single chord priming.

    abstract::In this study, we examine through electrophysiological measures three alternative mechanisms underlying musical chord priming: psychoacoustic distance, common parent-key, and distance along the circle of fifths. In contrast with previous behavioral studies, we present complex tones which do not blur the melodic compon...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e32832bfcaf

    authors: Granot RY,Hai A

    更新日期:2009-06-17 00:00:00

  • An IP3-assisted form of Ca2+-induced Ca2+ release in neocortical neurons.

    abstract::Calcium increases induced by single action potentials in rat visual cortex layer II/III pyramidal neurons were shown to be augmented by muscarinic acetylcholine receptor (mAchR) stimulation. This augmentation was drastically reduced by intracellular injection of heparin but not ruthenium red, therefore involving inosi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200002280-00022

    authors: Yamamoto K,Hashimoto K,Isomura Y,Shimohama S,Kato N

    更新日期:2000-02-28 00:00:00

  • Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats.

    abstract::The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200112210-00022

    authors: Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

    更新日期:2001-12-21 00:00:00

  • Role of matrix metalloproteinase-9 in a mouse model for amyotrophic lateral sclerosis.

    abstract::The pathogenesis of amyotrophic lateral sclerosis remains poorly understood, but microglial and astroglial activation are thought to contribute to motor neuron death. Evidence suggests that matrix metalloproteinase-9 (MMP-9) is a mediator of this deleterious effect. In this study, we evaluated the effect of MMP-9 on t...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200503150-00003

    authors: Dewil M,Schurmans C,Starckx S,Opdenakker G,Van Den Bosch L,Robberecht W

    更新日期:2005-03-15 00:00:00

  • Event-related potentials in an emotional go/no-go task and remission of geriatric depression.

    abstract::Anterior cingulate integrity may be required for antidepressant response. To assess anterior cingulate processes related to treatment response, we studied error-related negativity and error positivity produced during an emotional go/no-go challenge, a task activating the rostral anterior cingulate. Twelve elderly pati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e328013ceda

    authors: Alexopoulos GS,Murphy CF,Gunning-Dixon FM,Kalayam B,Katz R,Kanellopoulos D,Etwaroo GR,Klimstra S,Foxe JJ

    更新日期:2007-02-12 00:00:00

  • Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map.

    abstract::We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200402090-00031

    authors: Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

    更新日期:2004-02-09 00:00:00

  • Working memory failure by stimulation of hippocampal adenosine A1 receptors in rats.

    abstract::THE highly selective adenosine A1 receptor agonist N6-cyclohexyladenosine (CHA) significantly increased the number of errors (attempts to pass through two incorrect panels of the three panel-gates at four choice points) in the working memory task with a three-panel runway setup, when injected bilaterally at 0.3 and 1....

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199611250-00043

    authors: Ohno M,Watanabe S

    更新日期:1996-11-25 00:00:00

  • Interocular suppression in cat striate cortex is not orientation selective.

    abstract::For the majority of neurones in cat striate cortex, the response to an optimal stimulus presented to one eye is suppressed when a stimulus of substantially different orientation is presented to the other eye. In order to determine the true orientational tuning of the underlying inhibitory interactions in the absence o...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199511000-00032

    authors: Sengpiel F,Freeman TC,Blakemore C

    更新日期:1995-11-13 00:00:00

  • Functional asymmetry in primary auditory cortex for processing musical sounds: temporal pattern analysis of fMRI time series.

    abstract::Hemispheric differences in the temporal processing of musical sounds within the primary auditory cortex were investigated using functional magnetic resonance imaging (fMRI) time series analysis on a 3.0 T system in right-handed individuals who had no formal training in music. The two hemispheres exhibited a clear-cut ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3283475828

    authors: Izumi S,Itoh K,Matsuzawa H,Takahashi S,Kwee IL,Nakada T

    更新日期:2011-07-13 00:00:00

  • Sleeping brain, learning brain. The role of sleep for memory systems.

    abstract::The hypothesis that sleep participates in the consolidation of recent memory traces has been investigated using four main paradigms: (1) effects of post-training sleep deprivation on memory consolidation, (2) effects of learning on post-training sleep, (3) effects of within sleep stimulation on the sleep pattern and o...

    journal_title:Neuroreport

    pub_type: 杂志文章,评审

    doi:10.1097/00001756-200112210-00001

    authors: Peigneux P,Laureys S,Delbeuck X,Maquet P

    更新日期:2001-12-21 00:00:00

  • Lung inflation inhibits rapidly adapting receptor relay neurons in the rat.

    abstract::Pulmonary slowly adapting receptors (SARs) and rapidly adapting receptors (RARs) are important components of various respiratory reflexes. In anesthetized, paralyzed and artificially ventilated rats, we found an inhibitory linkage from the former to the latter system at the level of their second-order relay neurons (P...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200006050-00023

    authors: Ezure K,Tanaka I

    更新日期:2000-06-05 00:00:00

  • Pattern of distribution and co-localization of NOS and ATP in the myenteric plexus of human fetal stomach and intestine.

    abstract::The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200001170-00002

    authors: Belai A,Burnstock G

    更新日期:2000-01-17 00:00:00

  • Long distance pathways of diffusion for dextran along fibre bundles in brain. Relevance for volume transmission.

    abstract::Texas Red-labelled dextran with a mol. wt of 3000 g mol-1, a marker for the extracellular space, was injected unilaterally into the neostriatum of adult rats (0.3-30 micrograms microliter-1) and its distribution evaluated 1 min to 5 h later. Diffusion in the neuropil was observed with clearance starting after 30 min. ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199505090-00014

    authors: Bjelke B,England R,Nicholson C,Rice ME,Lindberg J,Zoli M,Agnati LF,Fuxe K

    更新日期:1995-05-09 00:00:00