Abstract:
:The organization of the main olfactory bulb of an insectivore, the laboratory shrew (Suncus murinus), was studied morphologically. We found particular small spherical regions, nidi, at the border between the glomerular and external plexiform layer (EPL), which were intensely GAD positive, 30-60 microm in diameter, and where no olfactory nerves were seen. Around the nidus small calbindin D28k-positive GABAergic neurons, perinidal cells, were clustered. Furthermore, a distinctive type of newly discovered neurons, which we named tasseled cells, located at the middle of the EPL extended dendrites to the nidus, where their small tuft-like complicated branches made synapses with perinidal cells. The present study showed that the basic components of the olfactory bulb are not necessarily constant in all mammals.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Kosaka K,Kosaka Tdoi
10.1097/00001756-199902050-00012subject
Has Abstractpub_date
1999-02-05 00:00:00pages
267-73issue
2eissn
0959-4965issn
1473-558Xjournal_volume
10pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Although accumulating evidence suggests that there are significant anatomical and histological differences between the sulci and gyri of the cerebral cortex, whether there is a difference in the distribution of interneurons between the two cortical regions remains largely unknown. In this study, we systematically comp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001309
更新日期:2019-10-16 00:00:00
abstract::Spinally administered adenosine reduces hypersensitivity in animals and humans with nerve injury, but also causes transient pain in humans and reduces tonic inhibition in spinal neurons. Nerve injury results in increased tonic spinal cord adenosine A1 receptor activation, consistent with a role for adenosine to genera...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000239949.37825.e9
更新日期:2006-10-23 00:00:00
abstract::Perception of apparent motion operates somewhat differently for objects and human figures. Depending on the interstimulus interval, the latter d may give rise to either perception of a direct path (i.e. biologically impossible) or indirect path (i.e. biologically possible). Here, PET was used to investigate whether a ...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-200001170-00022
更新日期:2000-01-17 00:00:00
abstract::The whole-cell patch clamp technique was used to investigate the actions of the opioid agonist U50488H on Ca2+ and K+ currents in differentiated NG108-15 cells. U50488H (5-50 microM) caused a concentration-dependent, reversible inhibition of high voltage-activated Ca2+ currents which persisted in the presence of nifed...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199607290-00024
更新日期:1996-07-29 00:00:00
abstract::Oleic acid, a cis-unsaturated free fatty acid, is proposed to be involved in the protein kinase C (PKC) activation pathway. Its biological actions, however, have not been well-characterized. We examined the effects of oleic acid on acetylcholine (ACh)-gated channel currents using Torpedo nicotinic ACh receptors expres...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199702100-00004
更新日期:1997-02-10 00:00:00
abstract::In acute experiments, the effects of i.p. 17beta-estradiol on the activity of arcuate neurons were studied in ovariectomized rats. 17Beta-estradiol (100 microg/100g, i.p.) increased the spontaneous activity of the observed arcuate neurons with a latency of 20-25 min. In some neurons spontaneous activity could be influ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199911260-00034
更新日期:1999-11-26 00:00:00
abstract::When two cylinders are passively moved in-phase on the volar surface of the right second and third fingers, human subjects estimate the stimuli to originate from one object, whereas two separate objects are estimated for out-of-phase stimuli. While five blindfolded subjects performed this estimation task, brain activi...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-200304150-00012
更新日期:2003-04-15 00:00:00
abstract::In the absence of vision of the limb, movements toward a visual target exhibit substantial errors which are considered to originate mainly in the visuomotor transformation process. To determine the time-dependent property of human visuomotor transformation, we investigated the error sequences in movements toward visua...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200405190-00010
更新日期:2004-05-19 00:00:00
abstract::Astrocytes induce blood-brain barrier (BBB) properties in brain endothelial cells (EC)*O(2)*, generated in blood and EC, opens the BBB. Hence, high activity of superoxide dismutase (SOD) is a prerequisite for normal BBB function. Therefore, the influence of rat astrocytes on the expression of manganese (Mn)SOD in rat ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200108080-00045
更新日期:2001-08-08 00:00:00
abstract::Low, nonsedative doses of γ-hydroxybutyric acid (GHB) produce short-term anterograde amnesia in humans and memory impairments in experimental animals. We have previously shown that acute systemic treatment of GHB in adolescent female rats impairs the acquisition, but not the expression, of contextual fear memory while...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000586
更新日期:2016-06-15 00:00:00
abstract::In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....
journal_title:Neuroreport
pub_type: 临床试验,杂志文章
doi:10.1097/00001756-199907130-00028
更新日期:1999-07-13 00:00:00
abstract::Blood oxygen level dependent MRI was used to test whether cocaine-stimulated mesolimbic activity varied with sexual receptivity. Rats were randomly screened for lordotic responses and were then imaged for their responses to centrally administered cocaine. We observed that female rats expressing no lordosis showed a gr...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283416f81
更新日期:2011-01-05 00:00:00
abstract::Event-related brain potential studies show that negative feedback in guessing tasks elicits a medial frontal negativity. Most theory and experimentation concerning this feedback-related negativity (FRN) has assumed that the FRN has little relationship to the perceptual characteristics of the feedback. This study chall...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32832a3250
更新日期:2009-04-22 00:00:00
abstract::N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000077549.91466.4c
更新日期:2003-07-18 00:00:00
abstract::This study is to explore the involvement of muscarinic acetylcholine receptors/protein kinase C cascade and the mitogen-activated protein kinase pathway in the effect of huperzine A on the secretory amyloid precursor protein-alpha. Upregulation of secretory amyloid precursor protein-alpha by huperzine A was attenuated...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3280c1e28c
更新日期:2007-05-07 00:00:00
abstract::Palmitoylethanolamine (PEA) is a ligand at peroxisome proliferator-activated receptors-α (PPARα), a nuclear receptor that has anti-inflammatory effects. Herein, complete Freund's adjuvant (CFA)-induced inflammatory pain model in rats and in-vitro calcium imaging studies were used to evaluate the mechanisms that underl...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001161
更新日期:2019-01-02 00:00:00
abstract::Intra-ischemic hypothermia is known to protect neurons against ischemic injury. Microglial cells have been shown to become activated following ischemia and are speculated to play significant roles in the evolution of ischemic neuronal injury. In this study, we examined the effect of intra-ischemic hypothermia on the m...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199703030-00026
更新日期:1997-03-03 00:00:00
abstract::Glial cell-line neurotrophic factor (GDNF), a neurotrophic factor with heparin binding affinity, promotes the survival and differentiation of a variety of neuronal cells including dopaminergic neuron. The effect of heparin on GDNF signaling was investigated based on the expression of the tyrosine hydroxyrase (TH) gene...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200210280-00016
更新日期:2002-10-28 00:00:00
abstract::This study was designed to clarify the neuroprotective effects of tanshinone IIA (TSA) following cerebral ischemic insult. Adult Sprague-Dawley rats were operated upon to achieve a middle cerebral artery occlusion to cause transient focal cerebral ischemia, which were then randomly divided into the sham-operated contr...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000559
更新日期:2016-04-13 00:00:00
abstract::Nerve growth factor (NGF) promotes the survival of several neuronal populations, but recently it has also been shown to induce neuronal cell death. Here we report the effects of NGF on lesioned motoneurons. We have analyzed facial and sciatic motoneurons in newborn and adult BALB/c and C57BL/6 mice, in addition to mic...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:2000-05-15 00:00:00
abstract::Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283405bad
更新日期:2010-12-08 00:00:00
abstract::The pattern of immunoreactivity for amyloid precursor (APP) and B-cell lymphoma protooncogene (Bcl-2) proteins in the rat retina was studied after intravitreal injection of basic fibroblast growth factor (bFGF) or transforming growth factor-beta (TGFbeta). In normal control retinas, intense immunostaining of APP and B...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199902250-00012
更新日期:1999-02-25 00:00:00
abstract::The role of the medial septum in suppressing paradoxical sleep and promoting slow wave sleep was suggested on the basis of neurotoxic lesion studies. However, these conclusions need to be substantiated with further experiments, including chemical stimulation studies. In this report, the medial septum was stimulated in...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3283533692
更新日期:2012-05-09 00:00:00
abstract::By means of magnetoencephalography we investigated the auditory-evoked fields (AEFs) elicited by broadband noise bursts in a gap-detection paradigm in children. AEFs of 16 healthy children (mean age 8.7 years) were recorded while they passively listened to 100-ms white-noise bursts with temporal gaps of 3, 6, 10 and 3...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282f0b6e2
更新日期:2007-10-29 00:00:00
abstract::Expression of the lipophilic ligand transporter, apolipoprotein D (apoD) by primary astrocyte cultures derived from neonatal mouse brain was investigated. Western blot analysis of cell lysates and media showed that apoD is constitutively secreted by astrocytes with little intracellular storage. The secreted apoD float...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199503000-00017
更新日期:1995-03-07 00:00:00
abstract::We aimed to ascertain whether pyrethroid insecticides could influence the vesicular transport of the excitatory amino acid glutamate. The incubation of rat cortical synaptic vesicles with resmethrin and permethrin, consistently stimulated both ATP-dependent and -independent uptake of [3H]glutamate, while not evoking d...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199810260-00034
更新日期:1998-10-26 00:00:00
abstract:OBJECTIVE:The current study aims to investigate whether computer generated (CG) expressions of emotion evoke similar emotional appraisal processing in the lateral orbitofrontal cortex (lOFC) compared to real human expressions, as well as how speech cues would influence the processing. METHODS:Functional near-infrared ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001420
更新日期:2020-04-08 00:00:00
abstract::The interaction between the Ca(2+)-activated K+ currents (IK(Ca)) induced by acetylcholine (ACh), 1-aminocyclopentane-1S,3R-dicarboxylic acid (1S,3R)-ACPD) and caffeine in rat hippocampal CA1 neurones was investigated to examine the functional independence between IP3- and Ca(2+)-sensitive Ca2+ stores. Pretreatment wi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199605310-00020
更新日期:1996-05-31 00:00:00
abstract::This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199812210-00006
更新日期:1998-12-21 00:00:00
abstract::We studied the neural activation associated with the expectancy of emotional stimuli using whole brain fMRI. Fifteen healthy subjects underwent fMRI scanning during which they performed a warned reaction task using emotional pictures carrying pleasant, unpleasant, or neutral content. The task involved an expected or u...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200301200-00010
更新日期:2003-01-20 00:00:00