Heparin facilitates glial cell line-derived neurotrophic factor signal transduction.

abstract：:Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

journal_title：Neuroreport

authors： Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

更新日期：2013-10-02 00:00:00

abstract：:The inward rectifier Kir4.1, composed of KCNJ10 K channel subunits, plays an essential role in inner ear K homeostasis. We have investigated the developmental expression and localization of KCNJ10 (Kir4.1) in the guinea pig inner ear using semi-quantitative reverse transcription polymerase chain reaction and immunohis...

journal_title：Neuroreport

authors： Jin Z,Wei D,Järlebark L

更新日期：2006-04-03 00:00:00

abstract：:Familial Alzheimer's disease due to presenilin 1 (PSEN1) mutations shows considerable phenotypic variability with differences in neuropathology and neurological symptoms. Spastic paraparesis is a common neurological phenotype associated with Alzheimer's disease arising from PSEN1 mutations. To investigate whether know...

journal_title：Neuroreport

authors： Karlstrom H,Kwok JB,Gregory GC,Hallupp M,Brooks WS,Schofield PR

更新日期：2007-08-06 00:00:00

abstract：:Müller cells, as the predominant glial element in the sensory retina, play a crucial role in healthy and diseased retina. Overactivation of Müller cells in response to damage is detrimental to the retina tissue. Current research shows that inhibiting glial fibrillary acidic protein (GFAP), a sensitive indicator of Mül...

journal_title：Neuroreport

authors： Wang X,Shu Q,Ni Y,Xu G

更新日期：2018-12-05 00:00:00

abstract：:Automatic phrase-building processes were investigated in second-language (L2) learners of French (native German speakers). Event-related brain potentials were recorded while participants listened to syntactically or semantically correct or incorrect French sentences containing a subject-modifying relative clause. Phra...

journal_title：Neuroreport

authors： Isel F

更新日期：2007-12-03 00:00:00

abstract：:Two monkeys were trained to perform wrist movements to align a pointer with visual targets. In the spatially 'compatible' condition, monkeys had to point at the target position (left/right), whereas in the 'incompatible' condition, they had to point at the position opposite to the target. A large proportion of neurone...

journal_title：Neuroreport

authors： Riehle A,Kornblum S,Requin J

更新日期：1994-12-20 00:00:00

abstract：:Disturbances in methyl-carbon metabolism, which result in hyperhomocysteinemia, have been associated with schizophrenia. Homozygosity for the T677 allele of the methylenetetrahydrofolate reductase (MTHFR) gene, which encodes for a thermolabile enzyme associated with hyperhomocysteinemia, has been found to be increased...

journal_title：Neuroreport

authors： Virgos C,Martorell L,Simó JM,Valero J,Figuera L,Joven J,Labad A,Vilella E

更新日期：1999-07-13 00:00:00

abstract：:Aging and Alzheimer's disease (AD) are both characterized by memory impairments and sleep changes. We investigated the potential link between these disturbances, focusing on sleep spindles, involved in memory consolidation. Two episodic memory tasks were given to young and old healthy participants, as well as to AD pa...

journal_title：Neuroreport

authors： Rauchs G,Schabus M,Parapatics S,Bertran F,Clochon P,Hot P,Denise P,Desgranges B,Eustache F,Gruber G,Anderer P

更新日期：2008-07-16 00:00:00

abstract：:Cyclooxygenase (COX)-2 is constitutively expressed in the superficial dorsal horn of the spinal cord, but its role in the spinal cord is still unclear. We examined the effect of intrathecally administered NS398, a selective COX-2 inhibitor and indomethacin, an non-selective COX-1 and COX-2 inhibitor, on the developmen...

journal_title：Neuroreport

authors： Yamamoto T,Sakashita Y

更新日期：1998-12-01 00:00:00

abstract：:It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...

journal_title：Neuroreport

authors： Hirai D,Hosokawa T,Inoue M,Miyachi S,Mikami A

更新日期：2009-04-22 00:00:00

abstract：:After amputation of an arm the sensory map of the body changes radically, causing the sensory input from face to 'invade' the original hand area in the brain. As a result, touching the face of the amputee evokes tactile sensations on the phantom. These sensory referrals from the face to phantom hand occur in a stable,...

journal_title：Neuroreport

authors： Ramachandran VS,Brang D,McGeoch PD

更新日期：2010-07-14 00:00:00

abstract：:The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

journal_title：Neuroreport

authors： Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

更新日期：2001-12-21 00:00:00

abstract：:Light physiologically regulates the levels of c-Fos in the suprachiasmatic nucleus (SCN), but the identity of most of the cells that express this DNA-binding protein is unknown. To determine whether SCN c-Fos expression is restricted to neurons, we performed light microscopic double-label immunohistochemistry on secti...

journal_title：Neuroreport

authors： Bennett MR,Schwartz WJ

更新日期：1994-09-08 00:00:00

abstract：:Learning and memory are cognitive functions commonly impaired after surgery, especially in elderly patients. Our aim was to evaluate the effect of sevoflurane anaesthesia on episodic-like memory in young and aged wild-type mice and mice with altered nicotinic cholinergic neurotransmission (beta2KO). Mice learned objec...

journal_title：Neuroreport

authors： Wiklund A,Granon S,Faure P,Sundman E,Changeux JP,Eriksson LI

更新日期：2009-10-28 00:00:00

abstract：:Exosomes derived from Schwann cells have been known to have a variety of functions in the development and repair of the peripheral nervous system, and cyclic AMP (cAMP) is a key inducer of Schwann cell differentiation. In the present study, we aimed to study the effect of exosomes derived from differentiated Schwann c...

journal_title：Neuroreport

authors： Sohn EJ,Park HT,Shin YK

更新日期：2020-05-07 00:00:00

abstract：:Myristoylated alanine-rich C kinase substrate (MARCKS), an acidic protein associated with cell motility and phagocytosis, is activated upon phosphorylation by protein kinase C (PKC) and proline-directed protein kinases. In Alzheimer disease (AD), activated microglia expressing MARCKS migrates around senile plaques. We...

journal_title：Neuroreport

authors： Hasegawa H,Nakai M,Tanimukai S,Taniguchi T,Terashima A,Kawamata T,Fukunaga K,Miyamoto E,Misaki K,Mukai H,Tanaka C

更新日期：2001-08-08 00:00:00

abstract：:Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...

journal_title：Neuroreport

authors： Machner B,Sprenger A,Kömpf D,Heide W

更新日期：2005-09-08 00:00:00

abstract：:We examined the role of main and external cuneate nuclei neurons in processing sensory information during forelimb passive movement. We recorded activity of neurons using circular and figure-eight trajectories, at different speeds, in anaesthetized rats. A multivariate regression analysis was performed to correlate ne...

journal_title：Neuroreport

authors： Garifoli A,Caserta C,Bosco G,Lombardo SA,Casabona A,Perciavalle V

更新日期：2002-03-04 00:00:00

abstract：:GABAA receptor-independent effects of benzodiazepine receptor (BZ-R) agonists on calcium and barium spikes were recorded intracellularly in the presence of bicuculline from CA3 hippocampal cells of young and adult rats. Zolpidem (omega 1 BZ-R agonist), had no effects in young animals but decreased calcium and barium s...

journal_title：Neuroreport

authors： Rovira C,Ben-Ari Y

更新日期：1994-10-27 00:00:00

abstract：:Myelin basic proteins (MBPs) have been shown to be ADP-ribosylated in-vitro by cholera toxin in the presence of NAD. Since acid-soluble extracts of brain contain other proteins in the 14-32 kD range (such as histones) in addition to MBP's, the identification of the ADP-ribosylated proteins was uncertain. To determine ...

journal_title：Neuroreport

authors： Boulias C,Moscarello MA

更新日期：1990-11-01 00:00:00

abstract：:This study used functional magnetic resonance imaging to characterize hemodynamic activation patterns recruited when the participants viewed mixed social communicative messages during a common interpersonal exchange. Mixed messages were defined as conflicting sequences of biological motion and facial affect signals th...

journal_title：Neuroreport

authors： Zucker NL,Green S,Morris JP,Kragel P,Pelphrey KA,Bulik CM,LaBar KS

更新日期：2011-06-22 00:00:00

abstract：:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disease mediated by IgG1 or IgG3 antibodies to the GluN1 subunit of the NMDAR, resulting in downregulation of NMDARs. Early diagnosis, prompt reduction of anti-NMDAR antibodies, and removal of associated ovarian tumors when identified are importa...

journal_title：Neuroreport

authors： Filatenkov A,Richardson TE,Daoud E,Johnson-Welch SF,Ramirez DM,Torrealba J,Greenberg B,Monson NL,Rajaram V

更新日期：2017-09-27 00:00:00

abstract：:It is unclear whether the neural algorithm that underlies stereoscopic vision in birds incorporates both low level (camouflage breaking) and high level (depth ordering) comparisons of information available to each of the eyes. Both visual functions were successfully tested by examining transitive inference performance...

journal_title：Neuroreport

authors： van der Willigen RF,Frost BJ,Wagner H

更新日期：1998-04-20 00:00:00

abstract：:The restriction of herpes virus latency to mammalian sensory ganglia has led to a search for tissue-specific regulatory molecules in these neurons which alter viral gene expression. Based primarily on work in sensory-related cell lines, several prior reports have suggested that the POU-domain transcription factor Oct-...

journal_title：Neuroreport

authors： Turner EE,Fedtsova N,Rosenfeld MG

更新日期：1996-11-25 00:00:00

abstract：:We have investigated the hypothesis that the acute ischemic swelling of the radial dendrites connected to the inner hair cells (IHCs) is mediated by glutamatergic receptors. In control cochleas, after 20 min ischemia all the dendrites were dramatically swollen. Conversely, after a perfusion of 50 microM 6-7-dinitroqui...

journal_title：Neuroreport

authors： Pujol R,Puel JL,Eybalin M

更新日期：1992-04-01 00:00:00

abstract：:Humans use vestibular head-in-space information when redirecting gaze towards remembered target location in space. This study shows that neck input is also involved. Normal subjects performed saccades towards remembered locations in space of a previously seen target following passive horizontal rotations of the head o...

journal_title：Neuroreport

authors： Mergner T,Nasios G,Anastasopoulos D

更新日期：1998-05-11 00:00:00

abstract：:The function of the lateral part of the human cerebellum was investigated through cerebro-cerebellar functional connectivity. We propose a laterality index method to reveal a functional and possibly anatomical pathway between the cerebral cortex and the cerebellum. The brain activity involved in learning a visually-gu...

journal_title：Neuroreport

authors： Tamada T,Miyauchi S,Imamizu H,Yoshioka T,Kawato M

更新日期：1999-02-05 00:00:00

abstract：:We have evaluated the G1H line of transgenic mice overexpressing a familial ALS mutation of SOD1 (Gly-93-->Ala) in tasks assessing different aspects of motor function to determine how early these deficits could be detected and their order of appearance. The earliest deficits were observed in tests of muscle strength a...

journal_title：Neuroreport

authors： Barnéoud P,Lolivier J,Sanger DJ,Scatton B,Moser P

更新日期：1997-09-08 00:00:00

abstract：:This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...

journal_title：Neuroreport

authors： Matsumoto M,Nakagawa T,Higashi T,Kim TS,Kojima K,Kita T,Sakamoto T,Ito J

更新日期：2005-05-31 00:00:00

abstract：:Retinal on-bipolar cells possess specialized glutamate receptors which are coupled via a G-protein to the control of a cyclic GMP (cGMP) cascade. Whole-cell voltage clamp recordings were obtained from light-responsive on-bipolar cells in retinal slices of the dogfish. Inclusion of nitroprusside in the patch-pipette so...

journal_title：Neuroreport

authors： Shiells R,Falk G

更新日期：1992-10-01 00:00:00