The role of transient receptor potential vanilloid receptor 1 and peroxisome proliferator-activated receptors-α in mediating the antinociceptive effects of palmitoylethanolamine in rats.

abstract：:Inhibition, the process that overrides and reverses the execution of a thought, action, or emotion, is important in daily life. Sixteen healthy volunteers performed a parametrically modulated motor inhibition task during functional magnetic resonance imaging. Two results were observed: (1) increased error-related ante...

journal_title：Neuroreport

authors： Matthews SC,Simmons AN,Arce E,Paulus MP

更新日期：2005-05-12 00:00:00

abstract：:In line with a possible role of vergence in orienting visual attention, we sought to study this eye movement in young children to provide insights on face perception. For this purpose, we measured the modulation in the angle of eye vergence in a sample of 39 children aged 6-36 months and compared it when presenting st...

journal_title：Neuroreport

authors： Esposito FL,Supèr H

更新日期：2018-02-07 00:00:00

abstract：:Although beta-amyloid precursor protein (APP) has been suggested to play a role in neuronal survival and plasticity, the mRNA expression of APP has not been studied in terms of neuronal activity. In cultures of mouse cerebellar granule cells, we found that the levels of APP mRNA increased when a high concentration of ...

journal_title：Neuroreport

authors： Tabuchi A,Ishii A,Fukuchi M,Kobayashi S,Suzuki T,Tsuda M

更新日期：2004-06-07 00:00:00

abstract：:As manifestations of prion diseases include disturbances of hypothalamic and pituitary functions, we tested the hypothesis that the cellular prion protein (PrPC) has a role as modulator of the hypothalamic-pituitary-adrenal axis. The level of corticosterone and adrenocorticotropic hormone were compared in PrPC null (P...

journal_title：Neuroreport

authors： Sanchez-Alavez M,Criado JR,Klein I,Moroncini G,Conti B

更新日期：2008-10-08 00:00:00

abstract：:Demyelinated CNS axons can be remyelinated by Schwann cells. A recent study concluded that with time Schwann cell remyelination is replaced by oligodendrocyte remyelination [9]. To examine this, the extent of Schwann cell and oligodendrocyte remyelination at 4, 6.5 and 24 weeks was determined for ethidium bromide lesi...

journal_title：Neuroreport

authors： Gilson JM,Blakemore WF

更新日期：2002-07-02 00:00:00

abstract：:We have previously shown that hippocampal long-term potentiation (LTP), one form of synaptic plasticity that may underlie learning and memory, is attenuated by blocking neuron activity of the basolateral amygdala (BLA). In the present study we investigated the amygdala noradrenergic or cholinergic contribution to hipp...

journal_title：Neuroreport

authors： Ikegaya Y,Nakanishi K,Saito H,Abe K

更新日期：1997-09-29 00:00:00

abstract：:The reduced steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and 3 alpha,21-di-hydroxy-5 alpha-pregnan-20-one (allotetrahydroDOC) are potent ligands of GABAA receptors. This study examined the possible modulatory effect of these metabolites on GABA inhibition of somatostatin release in cultured hypot...

journal_title：Neuroreport

authors： Tapia-Arancibia L,André M,Belmar J,Arancibia S

更新日期：1995-10-02 00:00:00

abstract：:Apolipoprotein E (apoE) and the beta-amyloid peptide are both found in the senile plaques associated with Alzheimer's disease. Several studies have recently determined that apoE can prevent beta-amyloid fibril (Abetaf) formation in vitro. In vivo, apoE is normally associated with a lipid source. We show that both reco...

journal_title：Neuroreport

authors： Beffert U,Poirier J

更新日期：1998-10-05 00:00:00

abstract：:The precise role of prostaglandin-D-synthase (beta-trace protein), the major constituent of cerebrospinal fluid, is unclear. In the present study, a sensitive and highly specific fluoroimmunoassay was developed. The measurement of the enzyme levels in rat CSF revealed a developmental change in the CSF levels with the ...

journal_title：Neuroreport

authors： Kabeya K,Ishikawa K,Katakai K,Watanabe M,Ohe Y,Wakabayashi K,Mori M

更新日期：1998-03-30 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00

abstract：:24S-hydroxycholesterol, the primary oxidation product of cholesterol in the brain, plays a key role in cholesterol elimination and homeostasis. While the concentration of this neurotoxic oxysterol decreases with age, 24S-hydroxycholesterol is elevated in Alzheimer's disease. In this study, we examined the effects of 2...

journal_title：Neuroreport

authors： Alexandrov P,Cui JG,Zhao Y,Lukiw WJ

更新日期：2005-06-21 00:00:00

abstract：:The effect of huperzine A (HupA) on oxygen-glucose deprivation (OGD)-induced injury was investigated in the rat pheochromocytoma cell line PC12. OGD for 3 h and reoxygenation for 24 h triggered apoptosis characterized by chromatin condensation, nucleus fragmentation and DNA laddering. The temporal profile of c-jun, p5...

journal_title：Neuroreport

authors： Zhou J,Fu Y,Tang XC

更新日期：2001-07-20 00:00:00

abstract：:We investigated the effect of nitric oxide (NO) on N-methyl-D-aspartate (NMDA)-induced changes in levels of dopamine (DA) and its metabolite in the striatum using in vivo microdialysis. Local administration of 1mM NMDA into the striatum significantly augmented DA release in the striatum. Simultaneous administration of...

journal_title：Neuroreport

authors： Shibata M,Araki N,Ohta K,Hamada J,Shimazu K,Fukuuchi Y

更新日期：1996-01-31 00:00:00

abstract：:The amounts of three adenylyl cyclase (AC) subtypes in membranes from brain obtained post-mortem from patients with dementia of Alzheimer type (DAT) and controls were studied by Western blotting using polyclonal antibodies. AC subtypes were characterized by preabsorption by complementary peptides, species difference, ...

journal_title：Neuroreport

authors： Yamamoto M,Ozawa H,Saito T,Frölich L,Riederer P,Takahata N

更新日期：1996-11-25 00:00:00

abstract：:The aim of this study was to investigate the effects of congenital human cytomegalovirus infection on the expression levels of N-methyl-D-aspartate receptors (NRs) and Ca/calmodulin-dependent protein kinase II (CaMKII) in the hippocampal neurons of neonatal Sprague-Dawley (SD) rats. Pregnant SD rats were divided into ...

journal_title：Neuroreport

authors： Wu,Yang L,Bu X,Tang J,Fan X

更新日期：2017-03-22 00:00:00

abstract：:The presence and regulation of pituitary adenylate cyclase activating peptide (PACAP) was investigated in the adult rat superior cervical ganglion. Double-labelling immunofluorescence using specific antibodies against PACAP and vasoactive intestinal peptide (VIP) revealed a dense innervation of postganglionic sympathe...

journal_title：Neuroreport

authors： Klimaschewski L,Hauser C,Heym C

更新日期：1996-11-04 00:00:00

abstract：:Hypoxic-ischemic brain damage (HIBD) occurs due to intrauterine hypoxia ischemia influencing the energy supply for fetal brain cells, which affects the metabolism of the brain to make the brain suffer a severe damage. Erythropoietin (EPO), which regulates hemacytopoiesis, is a kind of cytokine. EPO is sensitive to hyp...

journal_title：Neuroreport

authors： Huang R,Zhang J,Ren C,Zhang X,Gu L,Dong Y,Zhang J,Zhang J

更新日期：2019-03-06 00:00:00

abstract：:The rat suprachiasmatic (SCN) contains a dense plexus of low-affinity p75 neurotrophin receptor (p75NTR)-immunoreactivity. In some SCN neurons, p75NTR is co-localized with vasoactive intestinal peptide (VIP). The present study examines the effect of third ventricle administration of 192 IgG-saporin immunotoxin on p75N...

journal_title：Neuroreport

authors： Moga MM

更新日期：1998-10-05 00:00:00

abstract：:Using quantitative autoradiography, the present study examined ionotropic glutamatergic receptor binding sites using [3H]dizocilpine, [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate, and [3H]kainate in the posterior cingulate cortex of schizophrenia patients and matched controls. We found a significant increa...

journal_title：Neuroreport

authors： Newell KA,Zavitsanou K,Huang XF

更新日期：2005-08-22 00:00:00

abstract：:The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile...

journal_title：Neuroreport

authors： Bourisly AK

更新日期：2016-09-28 00:00:00

abstract：:We earlier showed that leucine-rich glioma inactivated 3 (LGI3) colocalizes with amyloid beta peptide (Abeta) taken up by astrocytes both in vitro and in vivo, and that LGI3 accumulated with endocytosis-associated proteins in aged monkey brains. In this study, we confirmed that LGI3 localizes to the endocytic pathway ...

journal_title：Neuroreport

authors： Okabayashi S,Kimura N

更新日期：2008-08-06 00:00:00

abstract：:Phosphorus magnetic resonance spectroscopy was used to determine effects of acute and chronic alcohol exposure on brain intracellular free magnesium concentration (Mgf) and bioenergetic state in rats. Acute alcohol (3 mg kg-1, i.p.) resulted in a transient ( < 2h) decline in brain Mgf and cytosolic phosphorylation rat...

journal_title：Neuroreport

authors： Mullins PG,Vink R

更新日期：1995-08-21 00:00:00

abstract：:Functional imaging has struggled for two decades to establish a quantitative link between the neuronal activity and the change in signal obtained. This review proposes a division of neuronal activity into a component relating to the electrical discharge activity and a component relating to the size of the activated ne...

journal_title：Neuroreport

authors： Marcar VL,Loenneker T

更新日期：2004-09-15 00:00:00

abstract：:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower...

journal_title：Neuroreport

authors： Izaki Y,Takita M,Nomura M

更新日期：2001-05-08 00:00:00

abstract：:Immunohistochemistry was used to demonstrate urotensin I (UI), urotensin II (UII), and angiotensinogen (Ao)-like immunoreactivities (ir) in the CNS of Aplysia californica. The fish UI is a 41 amino acid peptide that has 50% identity with mammalian corticotropin-releasing factor (CRF). Identity also exists between UI a...

journal_title：Neuroreport

authors： Gonzalez GC,Roger I,Gonzalez E,Martinez-Padron M,Moore GJ,Lukowiak K

更新日期：1995-02-15 00:00:00

abstract：:Human morning/evening preferences has recently been reported to be associated with polymorphism of the 3' flanking region of the Clock gene, which was the first identified mammalian circadian clock gene. We recorded body temperature, spontaneous activity, electroencephalogram and electromyogram for 48 h in mice with J...

journal_title：Neuroreport

authors： Sei H,Oishi K,Morita Y,Ishida N

更新日期：2001-05-25 00:00:00

abstract：:A fundamental issue in neuronal and glial cells is how intracellular rises in Ca2+ are coupled to signaling cascades and changes in subcellular morphology. We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS. Here, we demonstrate the pr...

journal_title：Neuroreport

authors： Clemen CS,Herr C,Lie AA,Noegel AA,Schröder R

更新日期：2001-05-08 00:00:00

abstract：:Primate vision consists mostly of periods of stable fixation separated by rapid saccadic eye movements. Each saccade brings a new scene onto the retina, and each new scene results in a burst of activity in the neurons of visual cortex. It might be expected that the activity of these neurons should only represent what ...

journal_title：Neuroreport

authors： Gawne TJ,Woods JM

更新日期：2003-01-20 00:00:00

abstract：:Calpain activation has been implicated in the pathogenesis of Alzheimer's disease. Okadaic acid, a protein phosphatase-2A inhibitor, has been used in Alzheimer's disease research models to increase tau phosphorylation and induce neuronal death. We previously reported that okadaic acid induced predominant activation of...

journal_title：Neuroreport

authors： Yoon S,Choi J,Huh JW,Hwang O,Kim D

更新日期：2006-05-15 00:00:00

abstract：:In situ hybridization and Northern blotting were used to study the expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat brain following photochemical stroke. A focal thrombotic lesion of the sensorimotor cortex was produced by intravenously injecting the light-sensitive dye rose bengal and exposing t...

journal_title：Neuroreport

authors： Comelli MC,Seren MS,Guidolin D,Manev RM,Favaron M,Rimland JM,Canella R,Negro A,Manev H

更新日期：1992-06-01 00:00:00