Abstract:
:Inhibition, the process that overrides and reverses the execution of a thought, action, or emotion, is important in daily life. Sixteen healthy volunteers performed a parametrically modulated motor inhibition task during functional magnetic resonance imaging. Two results were observed: (1) increased error-related anterior cingulate cortex activation and, (2) increased inferior frontal gyrus and medial prefrontal cortex activation during inhibition, irrespective of errors. Thus, the parametric nature of the task elucidated a functional dissociation of brain structures involved in motor inhibition from those involved in error processing. Additionally, this task allowed the identification of unique areas of increased activation within specific subregions of the anterior cingulate cortex related to errors made during trials with a high (dorsal anterior cingulate cortex) and low (ventral anterior cingulate cortex) inhibitory load.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Matthews SC,Simmons AN,Arce E,Paulus MPdoi
10.1097/00001756-200505120-00020subject
Has Abstractpub_date
2005-05-12 00:00:00pages
755-60issue
7eissn
0959-4965issn
1473-558Xpii
00001756-200505120-00020journal_volume
16pub_type
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