Modification of cytokine secretion following mild emotional stimuli.

Abstract:

:In the present study, changes in the cytokine system (IL-1 beta, IL-2, IL-3, IL-6 and TNF alpha) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNF alpha, a decrease in that of IL-2 and of IL-3 with no change in IL-1 beta and in IL-6 secretion levels, was observed in response to mild negative emotional changes. A reversed cytokine secretion profile was found following positive mood changes, suggesting the hypothalamic-pituitary-adrenal axis and the autonomic nervous system, as possible mediators underlying these effects, specific to the nature of the emotion.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Mittwoch-Jaffe T,Shalit F,Srendi B,Yehuda S

doi

10.1097/00001756-199503270-00021

subject

Has Abstract

pub_date

1995-03-27 00:00:00

pages

789-92

issue

5

eissn

0959-4965

issn

1473-558X

journal_volume

6

pub_type

临床试验,杂志文章,随机对照试验
  • Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB-dependent inflammatory responses following experimental traumatic brain injury in rats.

    abstract::Previous studies have shown that isosteviol sodium (STVNa) protects against permanent cerebral ischemia injury by inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-mediated inflammatory responses. Overwhelming evidence shows that toll-like receptors (TLRs) are the upstream regula...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001033

    authors: Zan J,Zhang H,Lu MY,Beng HM,Zhong KL,Sun XO,Tan W

    更新日期:2018-07-04 00:00:00

  • Radiation-induced cerebellar-cerebral functional connectivity alterations in nasopharyngeal carcinoma patients.

    abstract::The current study aimed to investigate the altered cerebellar-cerebral functional connectivity (FC) induced by radiotherapy to nasopharyngeal carcinoma (NPC) patients. Twenty-four NPC patients without treatment, and 35 NPC patients receiving radiotherapy underwent functional MRI scanning. Montreal cognitive assessment...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000813

    authors: Ma Q,Zeng LL,Qin J,Luo Z,Su J,Wu D,Qiu S,Hu D

    更新日期:2017-08-16 00:00:00

  • Cortical evoked potentials due to motion contrast in the blind hemifield.

    abstract::Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199911260-00024

    authors: Benson PJ,Guo K,Hardiman MJ

    更新日期:1999-11-26 00:00:00

  • Non-invasive single-trial monitoring of human movement-related brain activation based on DC-magnetoencephalography.

    abstract::Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulati...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200106130-00034

    authors: Mackert BM,Wübbeler G,Leistner S,Trahms L,Curio G

    更新日期:2001-06-13 00:00:00

  • The representation of articulation in the primary sensorimotor cortex.

    abstract::Bilabial, alveolar and velar sounds are produced at different locations around the oral cavity. fMRI was used to localize cortical representation of articulation in seven healthy subjects during repetitive lip and vertical tongue movements as well as repetitive articulation of /pa/ (bilabial), /ta/ (alveolar), /ka/ (v...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200009110-00032

    authors: Lotze M,Seggewies G,Erb M,Grodd W,Birbaumer N

    更新日期:2000-09-11 00:00:00

  • Neurometabolite changes in patients with complex regional pain syndrome using magnetic resonance spectroscopy: a pilot study.

    abstract::The aim of this study was to investigate distinct neurometabolites in the right and left thalamus and insula of patients with complex regional pain syndrome (CRPS) compared with healthy controls using proton magnetic resonance spectroscopy. Levels of N-acetylaspartate (NAA), N-acetylaspartylglutamate (NAAG), myo-inosi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001168

    authors: Jung YH,Kim H,Jeon SY,Kwon JM,Kim YC,Lee WJ,Lee D,Lee JY,Moon JY,Kang DH

    更新日期:2019-01-16 00:00:00

  • Ultrastructural localization of P2X3 receptors in rat sensory neurons.

    abstract::We used isolated IgG antibodies selective for P2X3 receptors to study the ultrastructural distribution of these receptors in rat sensory neurons. In trigeminal ganglia, P2X3 receptor immunoreactivity occurred in small and large nerve cell bodies and their processes. Endoplasmic reticulum and Golgi apparatus were heavi...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199808030-00022

    authors: Llewellyn-Smith IJ,Burnstock G

    更新日期:1998-08-03 00:00:00

  • Intrathecal and systemic R-phenylisopropyl-adenosine reduces scratching behaviour in a rat mononeuropathy model.

    abstract::The aim of the present study was to investigate the effect of intravenous or intrathecal (i.t.) administration of R-phenylisopropyladenosine (R-PIA), a selective A1 adenosine receptor agonist, on spontaneous scratching behaviour, a phenomenon presumably related to pain in a mononeuropathy model (sciatic nerve ligation...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199607290-00034

    authors: Sjölund KF,Sollevi A,Segerdahl M,Hansson P,Lundeberg T

    更新日期:1996-07-29 00:00:00

  • Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats.

    abstract::Protease-activated receptor-2 (PAR-2), a member of the G protein-coupled, seven trans-membrane domain receptor family, is activated by trypsin/tryptase and present in various tissues including the primary sensory neurons, playing a role in development of neurogenic inflammation. The present study examined if activatio...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200103260-00020

    authors: Kawabata A,Kawao N,Kuroda R,Tanaka A,Itoh H,Nishikawa H

    更新日期:2001-03-26 00:00:00

  • α1-Adrenoceptors in the hippocampal dentate gyrus involved in learning-dependent long-term potentiation during active-avoidance learning in rats.

    abstract::The hippocampus is the key structure for learning and memory in mammals and long-term potentiation (LTP) is an important cellular mechanism responsible for learning and memory. The influences of norepinephrine (NE) on the modulation of learning and memory, as well as LTP, through β-adrenoceptors are well documented, w...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000679

    authors: Lv J,Zhan SY,Li GX,Wang D,Li YS,Jin QH

    更新日期:2016-11-09 00:00:00

  • NMDA blockade attenuates caspase-3 activation and DNA fragmentation after neonatal hypoxia-ischemia.

    abstract::The aim was to study the effects of an NMDA receptor antagonist on caspase-3 activation and DNA fragmentation after hypoxia-ischemia (HI) in 7-day-old rats. Animals were treated with vehicle or MK-801 (0.5 mg/kg) directly after HI and sacrificed 8, 24 or 72h later. MK-801 reduced injury (by 53%), cells positive for ac...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200009110-00002

    authors: Puka-Sundvall M,Hallin U,Zhu C,Wang X,Karlsson JO,Blomgren K,Hagberg H

    更新日期:2000-09-11 00:00:00

  • CEP-1347 promotes survival of NGF responsive neurones in primary DRG explants.

    abstract::CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/01.wnr.0000070828.57864.ad

    authors: Bilsland JG,Harper SJ

    更新日期:2003-05-23 00:00:00

  • Expression of tPA mRNA in the facial nucleus following facial nerve transection in the rat.

    abstract::Plasminogen activators (PAs) have been suggested to play a role in neuronal migration and glial cell proliferation in the developing CNS. Less is known, however, about the role of PAs in the mature nervous system. To elucidate the role of tissue type plasminogen activator (tPA) in the nervous system we used in situ hy...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199701200-00008

    authors: Yuguchi T,Kohmura E,Yamada K,Otsuki H,Sakaki T,Yamashita T,Nonaka M,Sakaguchi T,Wanaka A,Hayakawa T

    更新日期:1997-01-20 00:00:00

  • The BOLD response: a new look at an old riddle.

    abstract::Functional imaging has struggled for two decades to establish a quantitative link between the neuronal activity and the change in signal obtained. This review proposes a division of neuronal activity into a component relating to the electrical discharge activity and a component relating to the size of the activated ne...

    journal_title:Neuroreport

    pub_type: 杂志文章,评审

    doi:10.1097/00001756-200409150-00001

    authors: Marcar VL,Loenneker T

    更新日期:2004-09-15 00:00:00

  • Acute marijuana effects on rCBF and cognition: a PET study.

    abstract::The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-200011270-00047

    authors: O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

    更新日期:2000-11-27 00:00:00

  • Asymmetries of representation in the visual system of pigeons.

    abstract::Although functional asymmetries in the course of visual information processing have been known for a long time in humans as well as in non-human species, the structural basis of these asymmetries is largely unknown. We now report that due to an asymmetry of commissural projections in the pigeon the left nucleus rotund...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199812210-00023

    authors: Güntürkün O,Hellmann B,Melsbach G,Prior H

    更新日期:1998-12-21 00:00:00

  • Pallial origin of mitral cells in the olfactory bulbs of Xenopus.

    abstract::We used two developmental transcription factors, x-Eomes (T-box family) and x-Lhx5 (LIM-homeodomain family), to follow the origin and development of the olfactory bulbs in Xenopus. During embryonic and larval development, x-Eomes and x-Lhx5 were expressed in highly similar patterns, in the lateral and latero-ventral w...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200312190-00013

    authors: Moreno N,Bachy I,Rétaux S,González A

    更新日期:2003-12-19 00:00:00

  • Local anaesthetics potentiate GABA-mediated Cl- currents by inhibiting GABA uptake.

    abstract::A two-electrode voltage clamp was used to examine the effects of the local anaesthetics (LAs) lidocaine, tetracaine and bupivacaine, and the meta-isomer of lidocaine (LL33), on the gamma-aminobutyric acid (GABA)-gated Cl- channel in the crayfish stretch receptor neurone. The voltage-induced current changes were record...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199701200-00018

    authors: Nordmark J,Rydqvist B

    更新日期:1997-01-20 00:00:00

  • An implantable device for neuropsychiatric rehabilitation by chronic deep brain stimulation in freely moving rats.

    abstract::Successful practice of clinical deep brain stimulation (DBS) calls for basic research on the mechanisms and explorations of new indications in animals. In the article, a new implantable, single-channel, low-power miniature device is proposed, which may transmit pulses chronically into the brain nucleus of freely movin...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000727

    authors: Liu H,Wang C,Zhang F,Jia H

    更新日期:2017-02-08 00:00:00

  • Oxidative damage to muscle protein in Duchenne muscular dystrophy.

    abstract::The hypothesis that reactive free radical species (ROS) may contribute to the pathogenesis of Duchenne muscular dystrophy (DMD) has been suggested previously, but experimental data obtained in support of the above have to date proved inconclusive. The recent discovery that nitric oxide synthase (required for muscle re...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199612200-00070

    authors: Haycock JW,MacNeil S,Jones P,Harris JB,Mantle D

    更新日期:1996-12-20 00:00:00

  • Dominance for language and spatial processing: limited capacity of a single hemisphere.

    abstract::Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200506210-00027

    authors: Jansen A,Flöel A,Menke R,Kanowski M,Knecht S

    更新日期:2005-06-21 00:00:00

  • Human short latency cortical responses to somatosensory stimulation. A high resolution EEG study.

    abstract::Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp ...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199710200-00011

    authors: Urbano A,Babiloni F,Babiloni C,Ambrosini A,Onorati P,Rossini PM

    更新日期:1997-10-20 00:00:00

  • Gender differences in cerebral ascorbate levels and ascorbate loss in ischemia.

    abstract::Ascorbate and glutathione (GSH) are the primary water-soluble antioxidants in the CNS. Oxidative stress, sometimes indicated by loss of these antioxidants, has been linked to several clinical and experimental conditions, including cerebral ischemia. These conditions are also gender-linked, with greater incidence or se...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199507310-00005

    authors: Ferris DC,Kume-Kick J,Russo-Menna I,Rice ME

    更新日期:1995-07-31 00:00:00

  • Automatic grapheme processing in the left occipitotemporal cortex.

    abstract::In a previous event-related fMRI study, we showed that the left occipitotemporal cortex was specifically involved in the abstract categorization of visually presented alphabetic symbols. Here, we duplicate the fMRI study by measuring visual event-related potentials to verify whether the left posterior cortex supports ...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-200206120-00008

    authors: Gros H,Doyon B,Rioual K,Celsis P

    更新日期:2002-06-12 00:00:00

  • SIRT2 mediates oxidative stress-induced apoptosis of differentiated PC12 cells.

    abstract::Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000000192

    authors: Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

    更新日期:2014-08-06 00:00:00

  • Molecular cloning and expression of a human heart inward rectifier potassium channel.

    abstract::We have isolated a cDNA encoding an inwardly rectifying K+ channel (HH-IRK1) from human heart. The cDNA codes for a 427-amino acid protein, with two putative transmembrane domains and an H5 region. The primary structure of HH-IRK1 is homologous to that of the IRK1 channel cloned from a mouse macrophage-like cell line....

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199412000-00024

    authors: Raab-Graham KF,Radeke CM,Vandenberg CA

    更新日期:1994-12-20 00:00:00

  • Cortical categorization failure in 2-month-old infants at risk for dyslexia.

    abstract::Cortical auditory categorization was assessed in 2-month-old infants at genetic risk for dyslexia and controls. Manipulated /bAk/ and /dAk/ speech stimuli were used as frequently presented standards. The neuroelectric brain responses of the control infants were highly sensitive to the phoneme boundary that separated t...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0b013e3280c1e2bf

    authors: van Leeuwen T,Been P,van Herten M,Zwarts F,Maassen B,van der Leij A

    更新日期:2007-06-11 00:00:00

  • MiR-124-3p alleviates the dezocine tolerance against pain by regulating TRAF6 in a rat model.

    abstract::MicroRNAs (miRNAs) play important roles in drug tolerance and regulating pain. The purpose of the present study is to explore the regulatory mechanism of miR-124-3p on dezocine tolerance against pain in a rat model. The expression of miR-124-3p and TRAF6 in spinal cord of rats was detected by quantitative reverse-tran...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/WNR.0000000000001559

    authors: Huo Y,Zhang K,Zhang T,Han Y,Hu Z

    更新日期:2021-01-06 00:00:00

  • Angiotensinogen-like epitopes are present in the CNS of Aplysia california and co-localize with urotensin I- and urotensin II-like immunoreactivities in the cerebral ganglia.

    abstract::Immunohistochemistry was used to demonstrate urotensin I (UI), urotensin II (UII), and angiotensinogen (Ao)-like immunoreactivities (ir) in the CNS of Aplysia californica. The fish UI is a 41 amino acid peptide that has 50% identity with mammalian corticotropin-releasing factor (CRF). Identity also exists between UI a...

    journal_title:Neuroreport

    pub_type: 杂志文章

    doi:10.1097/00001756-199502000-00033

    authors: Gonzalez GC,Roger I,Gonzalez E,Martinez-Padron M,Moore GJ,Lukowiak K

    更新日期:1995-02-15 00:00:00

  • Neural mechanisms of the octave illusion: electrophysiological evidence for central origin.

    abstract::The octave illusion is experienced when two simultaneous tones, separated by one octave and presented to the opposite ears, are continuously reversed between the two ears. Subjects consistently report a sequence of alternating single tones: the high tone in the right ear and the low in the left. We wished to determine...

    journal_title:Neuroreport

    pub_type: 临床试验,杂志文章

    doi:10.1097/00001756-199612200-00060

    authors: Ross J,Tervaniemi M,Näätänen R

    更新日期:1996-12-20 00:00:00