Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats.

abstract：:We conducted semiautomated, atlas-based analyses of regional brain volume changes on MRIs of children and adolescents with Down syndrome (DS) (N=15), DS with comorbid autism spectrum disorder (ASD) (N=15), and age-matched or sex-matched typically developing controls (N=22). Selective volumetric changes were correlated...

journal_title：Neuroreport

authors： Carter JC,Capone GT,Kaufmann WE

更新日期：2008-04-16 00:00:00

abstract：:It is assumed that in esotropic cats the behavioural suppression of the nasal field reflects inhibition of the input conveyed through the temporal retinal afferents of the strabismic eye. We hypothesized that inhibition underlying the field defect might be actively operated by interocular competitive mechanisms. If so...

journal_title：Neuroreport

authors： Di Stefano M,Gargini C

更新日期：1995-06-19 00:00:00

abstract：:GPR39, an orphan G protein-coupled receptor, has been recently identified as the receptor for the bioactive peptide obestatin. Obestatin is secreted from the stomach and acts as an anti-appetite hormone. This activity is induced whether obestatin is administered intraperitoneally or intracerebroventricularly. GPR39 is...

journal_title：Neuroreport

authors： Jackson VR,Nothacker HP,Civelli O

更新日期：2006-05-29 00:00:00

abstract：:Caspase-2 has features of both initiator and effector caspases. Previously, we have shown that brain hypoxia-induced production of caspases 1, 3, 8, and 9 is Src kinase mediated, a nonreceptor intracellular family of kinases. The present study tests the hypothesis that hypoxia results in increased expression of caspas...

journal_title：Neuroreport

authors： Angelis D,Delivoria-Papadopoulos M

更新日期：2017-08-16 00:00:00

abstract：:The brain-derived neurotrophic factor (BDNF) affects the developing cerebellar granule cells. Exposure of 9-11-day-old primary cultures of rat cerebellar granule neurones for 3 h to a more depolarizing medium (additional 15-30 mM KCl) stimulated the release of glutamate and increased the BDNF mRNAs levels. This BDNF a...

journal_title：Neuroreport

authors： Favaron M,Manev RM,Rimland JM,Candeo P,Beccaro M,Manev H

更新日期：1993-09-03 00:00:00

abstract：:The effect of Co-dergocrine (Hydergine) on acetylcholine (ACh) release in the striatum and hippocampus has been studied by means of brain microdialysis and compared to the effect of SKF 38393 and of LY 171555 selective D1 and D2 dopamine (DA) receptor agonists, respectively. Co-dergocrine (1 and 5 mg kg-1 i.p.) as wel...

journal_title：Neuroreport

authors： Imperato A,Obinu MC,Dazzi L,Carta G,Mascia MS,Casu MA,Gessa GL

更新日期：1994-02-24 00:00:00

abstract：:The octave illusion is experienced when two simultaneous tones, separated by one octave and presented to the opposite ears, are continuously reversed between the two ears. Subjects consistently report a sequence of alternating single tones: the high tone in the right ear and the low in the left. We wished to determine...

journal_title：Neuroreport

authors： Ross J,Tervaniemi M,Näätänen R

更新日期：1996-12-20 00:00:00

abstract：:Based on the results of recent in vitro studies, tau has been proposed to be involved in regulating signal transduction through the phospholipase C-gamma (PLC-gamma) signaling pathway. The present study provides support for the physiological relevance of this hypothesis by demonstrating the existence of a tau-PLC-gamm...

journal_title：Neuroreport

authors： Jenkins SM,Johnson GV

更新日期：1998-01-05 00:00:00

abstract：:To investigate the origin of high-frequency somatosensory evoked potential (SEP) components, we recorded median nerve SEPs from the scalp and the depth in six monkeys. Laminar field potentials were analyzed in area 3b (N10; corresponding to human N20) and area 1 (P12; corresponding to human P25). After digital filteri...

journal_title：Neuroreport

authors： Shimazu H,Kaji R,Tsujimoto T,Kohara N,Ikeda A,Kimura J,Shibasaki H

更新日期：2000-08-21 00:00:00

abstract：:Bone marrow stromal cells are multipotent stem cells that have the potential to differentiate into bone, cartilage, fat and muscle. Recently, bone marrow stromal cells have been shown to have the capacity to differentiate into neurons under specific experimental conditions, using chemical factors. We now describe how ...

journal_title：Neuroreport

authors： Zurita M,Vaquero J,Oya S,Miguel M

更新日期：2005-04-04 00:00:00

abstract：:Surface texture can be perceived not only from tactile, but also from auditory and visual sensory cues. In our previous psychophysical study, we demonstrated that humans can recognize surface stickiness using only one kind of sensory modality without any difficulty. However, the brain regions that would be activated b...

journal_title：Neuroreport

authors： So Y,Kim SP,Kim J

更新日期：2020-03-25 00:00:00

abstract：:A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization re...

journal_title：Neuroreport

authors： Blümcke I,Brockhaus A,Scheiwe C,Rollbrocker B,Wolf HK,Elger CE,Wiestler OD

更新日期：1997-03-24 00:00:00

abstract：:Spatial neglect has been explained as an impairment in the representation of extrapersonal space. One account suggests that representations of extrapersonal space are spatially compressed following neglect. In support of this view it has been demonstrated that neglect patients systematically underestimate the size of ...

journal_title：Neuroreport

authors： Shaw A,Jackson SR,Harvey M,Newport R,Krämer T,Dow L

更新日期：1997-12-01 00:00:00

abstract：:Parturition plays a critical role in the full expression of maternal behavior in postpartum females, yet the precise mechanism remains unclear. Here we examined the role of parturition in the activation of Fos and FosB in the central oxytocin receptor (OTR) system in rats. Although expression of FosB, not Fos, was see...

journal_title：Neuroreport

authors： Lin SH,Kiyohara T,Sun B

更新日期：2003-08-06 00:00:00

abstract：:The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

journal_title：Neuroreport

authors： Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

更新日期：2000-12-18 00:00:00

abstract：:An fMRI investigation was conducted to determine whether patients with impaired face recognition, a deficit known as prosopagnosia, would show functional activation in the fusiform gyrus, the neural substrate for face processing, when viewing faces. While the patients did show activation in the fusiform gyrus, with si...

journal_title：Neuroreport

authors： Marotta JJ,Genovese CR,Behrmann M

更新日期：2001-06-13 00:00:00

abstract：:Presenilin-1 (PS-1) and amyloid precursor protein (APP) have been linked to the pathogenesis of Alzheimer's disease. While APP accumulation is well documented in several models of brain injury, the role of PS-1 levels in neurodegeneration, if any, remains to be elucidated. The current studies examined PS-1 and APP exp...

journal_title：Neuroreport

authors： Calingasan NY,Gandy SE,Gibson GE

更新日期：1997-07-28 00:00:00

abstract：:We examined differences in brain activity in response to two types of mechanical stimulation, which have been reported previously as being perceptually indistinguishable but having different impacts on autonomic reflexes. As an indicator of brain activity, glucose metabolism was evaluated by PET with 2-[F]fluoro-2-deo...

journal_title：Neuroreport

authors： Watanabe N,Ishii K,Hotta H,Oda K,Sakata M,Toyohara J,Ishiwata K

更新日期：2013-05-29 00:00:00

abstract：:The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed befo...

journal_title：Neuroreport

authors： Ohn SH,Park CI,Yoo WK,Ko MH,Choi KP,Kim GM,Lee YT,Kim YH

更新日期：2008-01-08 00:00:00

abstract：:Regional variation in the distribution of SP and NFT within the brain is well documented. Consideration of such variation is potentially of help in formulating models of disease progression. Several models propose that pathological changes in Alzheimer's disease (AD) progress in a step-wise fashion along neuronally co...

journal_title：Neuroreport

authors： Shukla C,Bridges LR

更新日期：1999-12-16 00:00:00

abstract：:Monoamine oxidase A (MAOA) enzymatically degrades biogenic amines such as norepinephrine, dopamine, and serotonin, and plays a key role in the regulation of their neurotransmission. Allelic variations at the MAOA locus have been implicated in the neurobiology of aggression and impulsivity. We investigated the possible...

journal_title：Neuroreport

authors： Lee BT,Ham BJ

更新日期：2008-03-26 00:00:00

abstract：:Anterior cingulate integrity may be required for antidepressant response. To assess anterior cingulate processes related to treatment response, we studied error-related negativity and error positivity produced during an emotional go/no-go challenge, a task activating the rostral anterior cingulate. Twelve elderly pati...

journal_title：Neuroreport

authors： Alexopoulos GS,Murphy CF,Gunning-Dixon FM,Kalayam B,Katz R,Kanellopoulos D,Etwaroo GR,Klimstra S,Foxe JJ

更新日期：2007-02-12 00:00:00

abstract：:To examine the relationship between plasma lipoproteins and apolipoproteins in men with convictions for violent offences, blood was obtained from 15 men with a history of violence who were serving prison sentences for violent offences, and 25 age-matched male controls from the staff of the Argyll and Bute Psychiatric ...

journal_title：Neuroreport

authors： Gray RF,Corrigan FM,Strathdee A,Skinner ER,van Rhijn AG,Horrobin DF

更新日期：1993-06-01 00:00:00

abstract：:Regional cerebral blood flow was measured with positron emission tomography in seven normal volunteers while they performed various script event verification tasks. The left frontal lobe, left anterior cingulate and the anterior part of the left superior temporal gyrus were more activated in the script event membershi...

journal_title：Neuroreport

authors： Partiot A,Grafman J,Sadato N,Flitman S,Wild K

更新日期：1996-02-29 00:00:00

abstract：:Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

journal_title：Neuroreport

authors： Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

更新日期：2014-08-06 00:00:00

abstract：:Little is known regarding opioid receptors in the human cerebellum. The present [11C]diprenorphine PET study investigated opioid receptor binding in the human cerebellum in vivo, and showed a differential binding level in cerebellar cortex, vermis and dentate nuclei. The additional study in vitro of opioid receptors i...

journal_title：Neuroreport

authors： Schadrack J,Willoch F,Platzer S,Bartenstein P,Mahal B,Dworzak D,Wester HJ,Zieglgänsberger W,Tölle TR

更新日期：1999-02-25 00:00:00

abstract：:The purpose of this study was to determine whether the system that underlies the mismatch negativity (MMN) of event-related potentials would operate on the basis of objects if stimuli were delivered in such a way as to create the impression of two objects. To this end, tones were alternated between ears with one combi...

journal_title：Neuroreport

authors： Ritter W,Sussman E,Molholm S

更新日期：2000-01-17 00:00:00

abstract：:Both ice-like protease and calpain have been shown to be involved in apoptosis in non-neuronal cells. Cultured rat cerebellar granule neurons undergo apoptosis when exposed to low potassium-containing medium. Calpain inhibitors 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid (PD150606) and N-acetyl-Leu-Leu-Met-CHO (c...

journal_title：Neuroreport

authors： Nath R,Raser KJ,McGinnis K,Nadimpalli R,Stafford D,Wang KK

更新日期：1996-12-20 00:00:00

abstract：:The neuroprotective effect of docosahexaenoic acid (DHA) on the glutamate-induced cytotoxicity in rat hippocampal cultures was investigated in the present study. DHA at 5-50 microg/ml successfully protected neurons against the cytotoxicity, markedly increased the cell viability, inhibited both nitric oxide (NO) produc...

journal_title：Neuroreport

authors： Wang X,Zhao X,Mao ZY,Wang XM,Liu ZL

更新日期：2003-12-19 00:00:00

abstract：:Event related potentials (ERP) were recorded from 29 electrode positions in 10 normal subjects while they performed a simplified version of the Wisconsin Card Sorting Test (WCST). The design focused on ERP differences between early and late trials within each WCST series. Topographic and dipole analyses confirmed the ...

journal_title：Neuroreport

authors： Barceló F,Rubia FJ

更新日期：1998-03-09 00:00:00