Moving tactile stimuli of fingers are integrated in the intraparietal and inferior parietal cortices.

abstract：:In order to ascertain whether disturbances of neurogenesis occur in chronic neurodegenerative disorders, we assessed hippocampal cell proliferation in the R6/1 transgenic mouse model of Huntington's disease (HD). Using BrdU labelling for dividing cells at two different time points (5 and 20 weeks) in transgenic and wi...

journal_title：Neuroreport

authors： Lazic SE,Grote H,Armstrong RJ,Blakemore C,Hannan AJ,van Dellen A,Barker RA

更新日期：2004-04-09 00:00:00

abstract：:We determined whether acute compensatory feeding pattern changes after bulbectomy persist on a chronic basis, or whether physiological adaptation occurs to normalize acute changes. Rats were randomized to olfactory bulbectomy or sham operation; all had jugular vein catheterization. Food intake, meal number and size we...

journal_title：Neuroreport

authors： Meguid MM,Koseki M,Yang ZJ,Gleason JR,Laviano A

更新日期：1997-04-14 00:00:00

abstract：:In the absence of vision of the limb, movements toward a visual target exhibit substantial errors which are considered to originate mainly in the visuomotor transformation process. To determine the time-dependent property of human visuomotor transformation, we investigated the error sequences in movements toward visua...

journal_title：Neuroreport

authors： Miyazaki M,Nakajima Y,Kadota H,Chitose K,Ohtsuki T,Kudo K

更新日期：2004-05-19 00:00:00

abstract：:Perception of apparent motion operates somewhat differently for objects and human figures. Depending on the interstimulus interval, the latter d may give rise to either perception of a direct path (i.e. biologically impossible) or indirect path (i.e. biologically possible). Here, PET was used to investigate whether a ...

journal_title：Neuroreport

authors： Stevens JA,Fonlupt P,Shiffrar M,Decety J

更新日期：2000-01-17 00:00:00

abstract：:We can report, that by the use of indirect immunofluorescence techniques, that rat spinal motoneurons contain galanin-like immunoreactivity (LI). Furthermore, that galanin and calcitonin gene-related peptide (CGRP)-LI coexist in a number of spinal motoneurons. Co-localization could be demonstrated as thoracic, lumbar ...

journal_title：Neuroreport

authors： Johnson H,Hökfelt T,Ulfhake B

更新日期：1992-04-01 00:00:00

abstract：:There is no unifying hypothesis to account for the anatomical distribution of neuropathology, the involvement of beta-amyloid precursor protein (beta APP) and the role of increasing age in triggering the Alzheimer disease process. We report here that layer II pre-alpha neurones in transentorhinal and entorhinal cortex...

journal_title：Neuroreport

authors： Roberts GW,Nash M,Ince PG,Royston MC,Gentleman SM

更新日期：1993-01-01 00:00:00

abstract：:Recent reports have suggested the existence of a causal relationship between impaired regression of multiple climbing fibre innervation and impaired motor coordination in protein kinase C gamma subunit (PKC gamma) mutant mice. In the present patch-clamp study, performed in thin cerebellar slices prepared from adult mu...

journal_title：Neuroreport

authors： Levenes C,Daniel H,Jaillard D,Conquet F,Crépel F

更新日期：1997-01-20 00:00:00

abstract：:Retinal on-bipolar cells possess specialized glutamate receptors which are coupled via a G-protein to the control of a cyclic GMP (cGMP) cascade. Whole-cell voltage clamp recordings were obtained from light-responsive on-bipolar cells in retinal slices of the dogfish. Inclusion of nitroprusside in the patch-pipette so...

journal_title：Neuroreport

authors： Shiells R,Falk G

更新日期：1992-10-01 00:00:00

abstract：:Two patterns of neuronal firing, bursting and regular spiking, are observed in the somatosensory cortex of anesthetized rats. The effects of excitatory amino acid receptor agonists and antagonists on these discharge types have been examined in vivo, in order to assess their involvement in the generation of such firing...

journal_title：Neuroreport

authors： Kobayashi T,Nagao T,Fukuda H,Hicks TP,Oka JI

更新日期：1993-06-01 00:00:00

abstract：:We produced NB3C4, a novel monoclonal antibody specific for oligodendrocytes, using human neuroblastoma IMR-32 cells. NB3C4 specifically recognized oligodendrocytes in the CNS, although it bound to neuroblastoma IMR-32 cells and oligodendrocytes in vitro. Double immunofluorescence staining of rat brain using NB3C4 and...

journal_title：Neuroreport

authors： Yoshimura K,Kametani F,Shimoda Y,Fujimaki K,Sakurai Y,Kitamura K,Asou H,Nomura M

更新日期：2001-02-12 00:00:00

abstract：:Slices of hippocampus were incubated with Arg-Gly-Asp (RGD) peptides known to block members of the integrin class of matrix receptors. Though the peptides caused no detectable difference in the amount of long-term potentiation (LTP) expressed in the CA1 field 1-2 min after induction with high frequency stimulation, th...

journal_title：Neuroreport

authors： Xiao P,Bahr BA,Staubli U,Vanderklish PW,Lynch G

更新日期：1991-08-01 00:00:00

abstract：:Age-related depletion of androgens in men results in functional impairments in androgen-responsive tissues, such as the brain, resulting in increased risk for Alzheimer's disease. To investigate the relationship between normal age-related hormone loss and Alzheimer's disease risk, we evaluated the brain and serum leve...

journal_title：Neuroreport

authors： Rosario ER,Chang L,Beckett TL,Carroll JC,Paul Murphy M,Stanczyk FZ,Pike CJ

更新日期：2009-11-25 00:00:00

abstract：:According to the previous research, metformin, a medication utilized for type 2 diabetes management, inhibits neural aging and reduces infarct size by enhancing angiogenesis in a mouse stroke model. What is more, metformin administration also promotes neural precursor cells proliferation, migration, as well as differe...

journal_title：Neuroreport

authors： Yuan R,Wang Y,Li Q,Zhen F,Li X,Lai Q,Hu P,Wang X,Zhu Y,Fan H,Yao R

更新日期：2019-02-06 00:00:00

abstract：:Dysfunctional glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. Abnormal expressions in schizophrenia of ionotropic glutamate receptors (iGluRs) and the proteins that regulate their trafficking have been found to be region and subunit specific in brain, suggesting that abnormal t...

journal_title：Neuroreport

authors： Tucholski J,Simmons MS,Pinner AL,McMillan LD,Haroutunian V,Meador-Woodruff JH

更新日期：2013-08-21 00:00:00

abstract：:Alzheimer disease (AD) patients show increased plasma levels of homocysteine, whose conversion to methionine is catalyzed by methionine synthase (MS). Although altered MS activity may result from the MS A2756G polymorphism, the latter's possible associ-ation with AD remains unexplored. To assess whether the MS A2756G ...

journal_title：Neuroreport

authors： Beyer K,Lao JI,Latorre P,Riutort N,Matute B,Fernández-Figueras MT,Mate JL,Ariza A

更新日期：2003-07-18 00:00:00

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:Neural salient serine/arginine-rich protein 1 (NSSR1) expression has been found in mouse cerebral neurons, cerebellar Purkinje cells, pyramidal neurons and granule cells of dentate gyrus and regulates the pre-mRNA splicing of genes important for neural functions. In this study, we demonstrated that NSSR1 is expressed ...

journal_title：Neuroreport

authors： Peng ZY,Lee SC,Chen XH

更新日期：2007-10-29 00:00:00

abstract：:The parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridine (MPP+) acts through inhibition of complex I of the electron transport chain. Recent evidence suggests that it may also act through inhibition of 2-ketoglutarate dehydrogenase complex (KDHC). We confirmed this observation in isolated rat liver mitochondria ...

journal_title：Neuroreport

authors： Joffe GT,Parks JK,Parker WD Jr

更新日期：1998-08-24 00:00:00

abstract：:Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...

journal_title：Neuroreport

authors： McClure MM,Threlkeld SW,Rosen GD,Holly Fitch R

更新日期：2005-08-22 00:00:00

abstract：:The present study was designed to test the hypothesis that nitric oxide (NO) plays a role in 2-deoxy-D-glucose (2-DG)-induced hypothermia. The body temperature of awake, unrestrained rats was measured before and after the administration of 2-DG, or N(G)-nitro-L-arginine methyl ester (L-NAME; a non-selective NOS inhibi...

journal_title：Neuroreport

authors： Carnio EC,Almeida MC,Fabris G,Branco LG

更新日期：1999-09-29 00:00:00

abstract：:Neonatal peripheral inflammation has been shown to alter the neural circuitry of the spinal cord in adult rats. However, the temporal and spatial changes in the distribution of primary afferent terminals immediately following a neonatal inflammatory stimulus remains unclear. In the present study we found that intrapla...

journal_title：Neuroreport

authors： Ling QD,Chien CC,Wen YR,Fu WM,Sun WZ

更新日期：2003-10-27 00:00:00

abstract：:The objective of this study was to investigate the effects of long-term mental abacus calculation training (MACT) on children's spatial attention orientation. Fifteen children with intensive MACT (MACT group) and 15 children without MACT (non-MACT group) were selected. The two groups of children were matched in age, s...

journal_title：Neuroreport

authors： Liu X,Sun Y

更新日期：2017-01-01 00:00:00

abstract：:Glutamate excitotoxicity has been suggested to play a role in amyotrophic lateral sclerosis (ALS), yet it remains unclear why some groups of motoneurons (MNs) are more vulnerable to degeneration than others. Our aim was to compare, in normal adult rats, the expression of Group I metabotropic glutamate receptors (mGluR...

journal_title：Neuroreport

authors： Laslo P,Lipski J,Funk GD

更新日期：2001-07-03 00:00:00

abstract：:Activation of mu-opioid receptors is critical to steroid regulation of female sexual behavior, lordosis, in rodents. Estrogen treatment activates mu-opioid receptors in the medial preoptic area inhibiting lordosis, but ultimately appears important for progesterone facilitation of lordosis. We investigated the role of ...

journal_title：Neuroreport

authors： Sinchak K,Shahedi K,Dewing P,Micevych P

更新日期：2005-10-17 00:00:00

abstract：:As the most numerous cell type in the brain, astrocytes are coupled via gap junction channels. It is believed that communication among astrocytes is normally regulated by extracellular ions, neurotransmitters and neuromodulators. However, the level of astrocytic coupling is altered in abnormal conditions such as strok...

journal_title：Neuroreport

authors： Bani-Yaghoub M,Felker JM,Naus CC

更新日期：1999-12-16 00:00:00

abstract：:Experimental animals and patients are immobilized to allow continuous monitoring of physiological parameters. Restraint stress affects brain neurotransmitter levels and induces expression of immediate early genes. Whether immobilization stress affects outcomes in newborn animals which have suffered a hypoxic-ischaemic...

journal_title：Neuroreport

authors： Thoresen M,Bågenholm R,Løberg EM,Apriccna F

更新日期：1996-01-31 00:00:00

abstract：:We evaluated the incentive motivational properties of MK-801 by determining its priming effect on drug-seeking behaviour following extinction of cocaine self-administration, an animal model for drug craving. Rats were allowed to self-administrate cocaine (0.5 mg/kg) or saline during 10 daily sessions. MK-801 (0.1-0.25...

journal_title：Neuroreport

authors： De Vries TJ,Schoffelmeer AN,Binnekade R,Mulder AH,Vanderschuren LJ

更新日期：1998-03-09 00:00:00

abstract：:This study was performed to test the hypothesis that diminution in the preovulatory luteinizing hormone (LH) surge in middle-aged (MA) rats may be related to altered activity in nitric oxide (NO)ergic neurons. To begin to test the hypothesis, gene expression of hypothalamic NO synthase (NOS), the enzyme that catalyzes...

journal_title：Neuroreport

authors： Sahu A

更新日期：1998-12-21 00:00:00

abstract：:Voltage-gated K+ channels (K(V)) regulate cell electrical properties, proliferation, migration, and death. Rotenone is a mitochondrial inhibitor, influencing activity of many channels that potentially participate in cell death processes, but its effect on K(V) channel in neurons remains unclear. This study used whole-...

journal_title：Neuroreport

authors： Gao XF,Wang W,He C

更新日期：2008-09-17 00:00:00

abstract：:The study was conducted to investigate the effect of serotonin depletion on nitric oxide-induced meningeal vascular response and cerebrovascular nociception. Nitroglycerin was infused i.v. to control and serotonin-depleted rats. Pial circulation was monitored by intravital fluorescent videomicroscopy and Fos immunorea...

journal_title：Neuroreport

authors： Srikiatkhachorn A,Anuntasethakul T,Phansuwan-Pujito P,Patumraj S,Kasantikul V

更新日期：2001-04-17 00:00:00