MK-801 reinstates drug-seeking behaviour in cocaine-trained rats.

abstract：:Adenovirus vectors containing a marker gene (lacZ from Escherichia coli) are potent for transferring the gene to neurones after intraparenchymal injections. Expression of the marker gene may lead to the synthesis of an enormous amount of beta-galactosidase which diffuses throughout the entire neurone, providing a 'Gol...

journal_title：Neuroreport

authors： Lisovoski F,Cadusseau J,Akli S,Caillaud C,Vigne E,Poenaru L,Stratford-Perricaudet L,Pericaudet M,Kahn A,Peschanski M

更新日期：1994-05-09 00:00:00

abstract：:The study was conducted to investigate the effect of serotonin depletion on nitric oxide-induced meningeal vascular response and cerebrovascular nociception. Nitroglycerin was infused i.v. to control and serotonin-depleted rats. Pial circulation was monitored by intravital fluorescent videomicroscopy and Fos immunorea...

journal_title：Neuroreport

authors： Srikiatkhachorn A,Anuntasethakul T,Phansuwan-Pujito P,Patumraj S,Kasantikul V

更新日期：2001-04-17 00:00:00

abstract：:There is abundant psychophysical evidence in humans suggesting the existence of parallel pathways subserving different aspects of vision. However, there is little direct proof of the neural structures underlying the two pathways. We present direct anatomical evidence that in the normal human optic tract fibres are seg...

journal_title：Neuroreport

authors： Tassinari G,Campara D,Balercia G,Chilosi M,Martignoni G,Marzi CA

更新日期：1994-07-21 00:00:00

abstract：:We previously reported that clusterin enhances astrocyte proliferation and extracellular signal-regulated kinase (ERK) activity. It, however, remains largely unknown how clusterin promotes cell growth. Here, we investigate the signaling pathway and related molecules underlying astrocyte proliferation by clusterin. Exo...

journal_title：Neuroreport

authors： Shim YJ,Shin YJ,Jeong SY,Kang SW,Kim BM,Park IS,Min BH

更新日期：2009-03-04 00:00:00

abstract：:Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...

journal_title：Neuroreport

authors： Orr-Urtreger A,Kedmi M,Rosner S,Karmeli F,Rachmilewitz D

更新日期：2005-07-13 00:00:00

abstract：:Mouse retinal explants were transfected with recombinant adenovirus vector carrying the green fluorescent protein (GFP) gene and the rat bcl-x(L) gene (Adeno-Bcl-xL) to determine its ability to protect retinal ganglion cells against apoptotic cell death and to promote retinal ganglion cell neurite regeneration. Adeno-...

journal_title：Neuroreport

authors： Oshitari T,Okada S,Tokuhisa T,Adachi-Usami E

更新日期：2003-06-11 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...

journal_title：Neuroreport

authors： Machner B,Sprenger A,Kömpf D,Heide W

更新日期：2005-09-08 00:00:00

abstract：:The regulation of glucocorticoid receptors and nuclear factor kappaB was evaluated in the spiral ganglion neurons after 4 h of restraint stress in the mouse cochlea. Immediately after restraint stress, glucocorticoid receptor protein expression was not altered in spiral ganglion neurons even though both the plasma cor...

journal_title：Neuroreport

authors： Tahera Y,Meltser I,Johansson P,Canlon B

更新日期：2006-06-26 00:00:00

abstract：:In the present study the effects of intracerebroventricular (ICV) administration of baclofen (0.1-5.0 nmol) was investigated on food intake in non-fasted rats. Baclofen (1.0, 2.5 and 5.0 nmol) increased food consumption in a dose-related manner during the first 15-30 min after administration. The effects of baclofen (...

journal_title：Neuroreport

authors： Ebenezer IS

更新日期：1990-09-01 00:00:00

abstract：:Caffeine is a widely self-administered psychostimulant with purported neuroprotective and procognitive effects in rodent models of aging. The cholinergic basal forebrain is important for arousal and attention and is implicated in age-related cognitive decline. Accordingly, we determined the effects of caffeine on chol...

journal_title：Neuroreport

authors： Reznikov LR,Pasumarthi RK,Fadel JR

更新日期：2009-12-09 00:00:00

abstract：:Neuroblastoma cell lines are useful for the investigation of neuronal receptor regulation since these cells display various neuronal features. Here we report the analysis of human AMPA and kainate receptor expression in four neuroblastoma cell lines (SK-N-MC, IMR-32, CHP 126 and NMB/N7). The reverse transcriptase-poly...

journal_title：Neuroreport

authors： Korczak B,McWhinnie EA,Fletcher EJ,Kamboj RK

更新日期：1995-04-19 00:00:00

abstract：:CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...

journal_title：Neuroreport

authors： Bilsland JG,Harper SJ

更新日期：2003-05-23 00:00:00

abstract：:Using a guessing paradigm we measured visual sensitivity in the blind and normal half-fields of four cerebrally hemidecorticated patients. In the blind field, sensitivity was reduced by approximately 3 long units. Stimuli which produced significant detection also evoked conscious sensations of light and colour. Contro...

journal_title：Neuroreport

authors： Stoerig P,Faubert J,Ptito M,Diaconu V,Ptito A

更新日期：1996-08-12 00:00:00

abstract：:Children with mathematical difficulties usually have an impaired ability to process symbolic representations. Functional MRI methods have suggested that early frontoparietal connectivity can predict mathematic achievements; however, the study of brain connectivity during numerical processing remains unexplored. With t...

journal_title：Neuroreport

authors： Gómez-Velázquez FR,Vélez-Pérez H,Espinoza-Valdez A,Romo-Vazquez R,Salido-Ruiz RA,Ruiz-Stovel V,Gallardo-Moreno GB,González-Garrido AA,Berumen G

更新日期：2017-02-08 00:00:00

abstract：:The role of the medial septum in suppressing paradoxical sleep and promoting slow wave sleep was suggested on the basis of neurotoxic lesion studies. However, these conclusions need to be substantiated with further experiments, including chemical stimulation studies. In this report, the medial septum was stimulated in...

journal_title：Neuroreport

authors： Mukherjee D,Kaushik MK,Jaryal AK,Kumar VM,Mallick HN

更新日期：2012-05-09 00:00:00

abstract：:Traumatic brain injury (TBI) is a major risk factor for Alzheimer's disease. Recent studies suggest that amyloid-beta (Aβ) deposit can be detected several years after TBI. However, it is unknown whether post-TBI Aβ deposits arise from short-term changes in Aβ metabolism or reflect a long-term sequela. To answer this q...

journal_title：Neuroreport

authors： Bagnato S,Andriolo M,Boccagni C,Galardi G

更新日期：2017-03-22 00:00:00

abstract：:We investigated the mode of action of argiotoxin636 on isolated N-methyl-D-aspartate (NMDA) receptor channels in cultured cerebellar granule cells. We found that the toxin blocks NMDA channels by decreasing their opening probability and by inducing a flickering activity, in a voltage-dependent manner. Our results indi...

journal_title：Neuroreport

authors： Fagni L,Bockaert J

更新日期：1995-05-09 00:00:00

abstract：:Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...

journal_title：Neuroreport

authors： Chao TI,Alzheimer C

更新日期：1995-09-11 00:00:00

abstract：:Retinal light exposure induces several immediate-early genes in the hypothalamic suprachiasmatic nucleus (SCN), which contains the major circadian pacemaker of mammals. Clock-controlled and light-induced genes expressed in the SCN such as c- and contain upstream regulatory elements similar to those of the major immedi...

journal_title：Neuroreport

authors： Sigworth LA,Liao L,Chandler TR,Geusz ME

更新日期：2003-03-03 00:00:00

abstract：:Predicting neuron death or survival after axonal injury is important in neurotrauma research. We now used in vivo confocal neuroimaging microscopy to repeatedly visualize retinal ganglion cells after optic nerve crush and studied their morphological alterations and ultimate fate. An intracollicular injection of a retr...

journal_title：Neuroreport

authors： Rousseau V,Engelmann R,Sabel BA

更新日期：1999-11-08 00:00:00

abstract：:Kisspeptin is distributed not only in brain areas for regulating reproduction but also in nuclei involved in feeding control. Whether kisspeptin alters food intake is unknown in mice. We examined how kisspeptin-10 influences feeding after intracerebroventricular injection in mice using automated monitoring. Kisspeptin...

journal_title：Neuroreport

authors： Stengel A,Wang L,Goebel-Stengel M,Taché Y

更新日期：2011-03-30 00:00:00

abstract：:Voltage-gated K+ channels (K(V)) regulate cell electrical properties, proliferation, migration, and death. Rotenone is a mitochondrial inhibitor, influencing activity of many channels that potentially participate in cell death processes, but its effect on K(V) channel in neurons remains unclear. This study used whole-...

journal_title：Neuroreport

authors： Gao XF,Wang W,He C

更新日期：2008-09-17 00:00:00

abstract：:Optic nerves of adult rats were crushed 2 mm behind the eye to examine the ability of retinal ganglion cells (RGCs) to regenerate their axons. Some animals were treated with the immunophilin ligands FK 506 or GPI 1046 for up to 4 weeks. After 10 days to 16 months, regenerating RGC axons were visualized using anterogra...

journal_title：Neuroreport

authors： Campbell G,Holt JK,Shotton HR,Anderson PN,Bavetta S,Lieberman AR

更新日期：1999-12-16 00:00:00

abstract：:It is known that interleukin-1beta facilitates pain, but the mechanisms of this are not understood. This study investigated the role of interleukin-1beta in the expression of Fos, a marker of neuronal activation, and hyperalgesia caused by injecting complete Freund's adjuvant into one hind paw of the rat. Interleukin-...

journal_title：Neuroreport

authors： Li A,Lao L,Wang Y,Zhang H,Ren K,Berman BM,Zhang R

更新日期：2007-03-26 00:00:00

abstract：:Flurothyl kindling initiates a time-dependent process that results in a facilitated propagation from the forebrain to the brainstem seizure system and in an increase in the complexity of behavioral seizure expression. We investigated the involvement of the ventromedial nucleus of the hypothalamus (VMH) in mediating th...

journal_title：Neuroreport

authors： Ferland RJ,Applegate CD

更新日期：1998-11-16 00:00:00

abstract：OBJECTIVE:The current study aims to investigate whether computer generated (CG) expressions of emotion evoke similar emotional appraisal processing in the lateral orbitofrontal cortex (lOFC) compared to real human expressions, as well as how speech cues would influence the processing. METHODS:Functional near-infrared ...

journal_title：Neuroreport

authors： Zhao T,Chen J,Wang L,Yan N

更新日期：2020-04-08 00:00:00

abstract：:We examined covert and overt orienting in response to non-predictive gaze direction cues and investigated whether the subcortical superior colliculus (SC) plays a role in this type of orienting. Participants viewed a centrally presented gazing schematic face and responded to targets appearing at gazed-at or non-gazed-...

journal_title：Neuroreport

authors： Friesen CK,Kingstone A

更新日期：2003-03-03 00:00:00

abstract：:It has been suggested that lower motor neurons containing calcium-binding proteins (CBP) may be resistant to degeneration in motor neuron disease. The testing of this hypothesis is hampered by lack of comprehensive information regarding the presence of CBPs in motor neurons. To address this shortcoming, we investigate...

journal_title：Neuroreport

authors： Fahandejsaadi A,Leung E,Rahaii R,Bu J,Geula C

更新日期：2004-03-01 00:00:00

abstract：:Two [O(15)] PET studies assessed sex differences regional brain activation in the recognition of emotional stimuli. Study I revealed that the recognition of emotion in visual faces resulted in bilateral frontal activation in women, and unilateral right-sided activation in men. In study II, the complexity of the emotio...

journal_title：Neuroreport

authors： Hall GB,Witelson SF,Szechtman H,Nahmias C

更新日期：2004-02-09 00:00:00