Glutamate microinjection in the medial septum of rats decreases paradoxical sleep and increases slow wave sleep.

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays critical roles in neurotransmission, synaptic plasticity, learning and memory. The aim of this study was to examine, by in situ hybridization, prefrontal cortical expression of CaMKII alpha mRNA in postmortem brains of unipolar, bipolar, schizophrenic, and con...

journal_title：Neuroreport

authors： Xing G,Russell S,Hough C,O'Grady J,Zhang L,Yang S,Zhang LX,Post R

更新日期：2002-03-25 00:00:00

abstract：:Expression of monocarboxylate transporter MCT1 was studied in archival tissues from human CNS using antibodies to the carboxyl-terminal end of MCT1. Sections of neocortex, hippocampus and cerebellum of brains from 10 adult autopsy patients who died from other than CNS disease, and from archival surgical biopsy specime...

journal_title：Neuroreport

authors： Froberg MK,Gerhart DZ,Enerson BE,Manivel C,Guzman-Paz M,Seacotte N,Drewes LR

更新日期：2001-03-26 00:00:00

abstract：:Voltage-dependent outward currents were examined in CA1 neurones by whole-cell recording in slices. Nine cells were recorded with the 'standard' internal solution (KMeSO4, HEPES, EGTA, CaCl2, and MgCl2) and held a potential (-54 +/- 3 mV) at which there was no significant outward current. Cromakalim (CROM, 100 microM)...

journal_title：Neuroreport

authors： Erdemli G,Krnjević K

更新日期：1994-06-27 00:00:00

abstract：:Recent experiments have suggested that the process of visuomotor adaptation depends on how a visual distortion is introduced. The cerebellum is thought to be involved in adapting to rapidly introduced visual distortions; however its role in adapting to a gradually introduced distortion is unknown. We tested adaptation...

journal_title：Neuroreport

authors： Robertson EM,Miall RC

更新日期：1999-04-06 00:00:00

abstract：:We constructed two replication-deficient recombinant adenovirus vectors coding human basic fibroblast growth factor (bFGF), one with and one without the interleukin-2 (IL-2) secretory signal sequence and examined their neurotrophic effects on primary neuronal cells in vitro. The primary neuronal cells were successfull...

journal_title：Neuroreport

authors： Matsuoka N,Miyatake S,Yukawa H,Takahashi JC,Saiki M,Mori H,Ishii K,Akimoto M,Hamada H,Hashimoto N

更新日期：2000-06-26 00:00:00

abstract：:The present study aims to study sequential alterations occurring in both dopaminergic neurons and microglia in substantia nigra (SN) following intrastriatal injection of 1-methyl-4-phenylpridium ion (MPP+) in rats. Heme oxygenase-1 (HO-1), a marker of oxidative stress, first appeared in dopaminergic neurons in SN at 1...

journal_title：Neuroreport

authors： Miwa H,Kubo T,Morita S,Nakanishi I,Kondo T

更新日期：2004-04-29 00:00:00

abstract：:In the present study the effects of intracerebroventricular (ICV) administration of baclofen (0.1-5.0 nmol) was investigated on food intake in non-fasted rats. Baclofen (1.0, 2.5 and 5.0 nmol) increased food consumption in a dose-related manner during the first 15-30 min after administration. The effects of baclofen (...

journal_title：Neuroreport

authors： Ebenezer IS

更新日期：1990-09-01 00:00:00

abstract：:The aim of this study was to show that Cl(-)-dependent excitotoxicity, with its characteristic cell swelling, involves actual water influx into the intracellular compartment. Taking advantage of the Ca2+ omission paradigm of Cl(-)-dependent excitotoxicity, in the chick embryonic neural retina ex vivo, which is associa...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramirez G

更新日期：2000-11-27 00:00:00

abstract：:Network tools have been extensively applied to study the properties of brain functional and anatomical networks. In this paper, resiliency of Caenorhabditis elegans cortical networks against cascaded failures is studied. To this end, directed network formed by chemical connections and undirected network formed by elec...

journal_title：Neuroreport

authors： Jalili M

更新日期：2015-08-19 00:00:00

abstract：:Monoamine oxidase A (MAOA) enzymatically degrades biogenic amines such as norepinephrine, dopamine, and serotonin, and plays a key role in the regulation of their neurotransmission. Allelic variations at the MAOA locus have been implicated in the neurobiology of aggression and impulsivity. We investigated the possible...

journal_title：Neuroreport

authors： Lee BT,Ham BJ

更新日期：2008-03-26 00:00:00

abstract：:The trans-sialidase (TS) of Trypanosoma cruzi induces survival and differentiation of neuronal and glial cells. This mechanism underlying survival is via phosphatidylinositol 3-kinase (PI3K) but how TS promotes neuronal differentiation remained to be determined. Here we show that TS-induced neurite outgrowth in PC12 c...

journal_title：Neuroreport

authors： Chuenkova MV,Pereira MA

更新日期：2001-12-04 00:00:00

abstract：:We have investigated the hypothesis that the acute ischemic swelling of the radial dendrites connected to the inner hair cells (IHCs) is mediated by glutamatergic receptors. In control cochleas, after 20 min ischemia all the dendrites were dramatically swollen. Conversely, after a perfusion of 50 microM 6-7-dinitroqui...

journal_title：Neuroreport

authors： Pujol R,Puel JL,Eybalin M

更新日期：1992-04-01 00:00:00

abstract：:A synchronizing volley of excitation was delivered to cells from the primary visual cortex of the anaesthetized cat by an electrical pulse stimulation of the optic radiations. In intracellular records, this resulted in an initial, fast depolarization of the membrane potential followed by a longer lasting (266 ms) hype...

journal_title：Neuroreport

authors： Ahmed B

更新日期：2000-04-27 00:00:00

abstract：:Pyramidal cells were injected intracellularly in fixed, flat-mounted cortical slices taken from the first and fourth visual areas (V1 and V4, respectively) and cytoarchitectonic areas TEO and TE of two age and gender-matched vervet monkeys and the size, branching complexity and spine density of their basal dendritic t...

journal_title：Neuroreport

authors： Elston GN,Benavides-Piccione R,Elston A,Manger P,DeFelipe J

更新日期：2005-06-21 00:00:00

abstract：:Transcription factors have been used as neuronal markers in the nucleus accumbens (ACB) of male juvenile spontaneously hypertensive rats (SHR), an animal model of attention-deficit hyperactivity disorder (ADHD), to trace putative neural substrates. In SHR, immunocytochemistry and PC-assisted image analysis showed lowe...

journal_title：Neuroreport

authors： Papa M,Sergeant JA,Sadile AG

更新日期：1997-05-06 00:00:00

abstract：:We compared various measures of visual-vestibular interaction in subjects with insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM), as well as non-diabetic controls. Subjects with IDDM exhibited significantly greater postural sway than controls on those conditions in the Clini...

journal_title：Neuroreport

authors： Darlington CL,Erasmus J,Nicholson M,King J,Smith PF

更新日期：2000-02-28 00:00:00

abstract：:The localization of the melanocortin 1 (MC1) receptor in brain was investigated by in situ hybridization and immunohistochemistry. In rat periaqueductal gray matter (PAG), a small number of cells which displayed a punctate distribution showed a specific hybridization signal for MC1 receptor mRNA, whereas other regions...

journal_title：Neuroreport

authors： Xia Y,Wikberg JE,Chhajlani V

更新日期：1995-11-13 00:00:00

abstract：:The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...

journal_title：Neuroreport

authors： Bonde C,Kristensen BW,Blaabjerg M,Johansen TE,Zimmer J,Meyer M

更新日期：2000-12-18 00:00:00

abstract：:We report the results of serial transcranial magnetic stimulation mapping of cortical motor outputs to the face and upper extremity in a subject studied before and repeatedly after traumatic amputation of the right arm immediately below the elbow. The results of the mapping studies illustrate the time course of plasti...

journal_title：Neuroreport

authors： Pascual-Leone A,Peris M,Tormos JM,Pascual AP,Catalá MD

更新日期：1996-09-02 00:00:00

abstract：:It has been reported that intracerebroventricular (i.c.v.) injection of nociception/orphanin FQ (OFQ) can antagonize morphine analgesia, whereas i.c.v. OFQ antibody can reverse morphine tolerance. Nocistatin (NST) is a recently characterized neuropeptide possessing an antagonizing effect on OFQ. Here we examine whethe...

journal_title：Neuroreport

authors： Sun RQ,Zhao CS,Wang HJ,Jing Z,Wang W,Yang K,Wang Y,Chang JK,Han JS

更新日期：2001-06-13 00:00:00

abstract：:Previous studies have demonstrated induced gamma-band activity (GBA) over posterior temporo-parietal and inferior frontal cortex during auditory spatial vs pattern mismatch processing, respectively. Here we investigated magnetoencephalographic oscillatory responses during an active auditory pattern oddball task. Fourt...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W

更新日期：2004-10-05 00:00:00

abstract：:In this study, an algorithm is introduced for the automatic detection and simultaneous topographic classification of interictal regional spike activity in pediatric surface EEG records. The algorithm is based on the classification of the topographic distribution of instantaneous power by means of a 'group' trained cla...

journal_title：Neuroreport

authors： Feucht M,Hoffmann K,Steinberger K,Witte H,Benninger F,Arnold M,Doering A

更新日期：1997-07-07 00:00:00

abstract：:Previous studies have indicated that estrogen protects the brain from ischemic damage and regulates K(ATP) channel activity; the present study was designed to address the involvement of K(ATP) channels in the neuroprotective effects of estrogen in focal cerebral ischemia: in experiment 1, K(ATP) mRNA and protein in th...

journal_title：Neuroreport

authors： Zhang D,Xia H,Xu L,Zhang C,Yao W,Wang Y,Ren J,Wu J,Tian Y,Liu W,Wang X

更新日期：2012-11-14 00:00:00

abstract：:TA20 cDNA was previously cloned as a neurite outgrowth factor from a hybridoma of mouse and rat cells, NG108-15. To clarify the detailed function and tissue distribution of this gene, homologous sequences of rat and mouse were identified. The cloned sequences had no homology with known genes, and was designated as spr...

journal_title：Neuroreport

authors： Tohda C,Jacobowitz DM

更新日期：1999-07-13 00:00:00

abstract：:BALB/c mice were trained in a partial acquisition session of an appetitive bar-pressing task. They then received an immediate post-acquisition i.p. injection of either saline or apamin 0.2 mg kg-1. Each group was submitted to a retention test that was delayed either 25, 85 or 180 min after initial acquisition. In sali...

journal_title：Neuroreport

authors： Belcadi-Abbassi W,Destrade C

更新日期：1995-06-19 00:00:00

abstract：:This study compared the visuospatial asymmetries in children with dyslexia and healthy children by using the manual line bisection task, and investigated the processing of spatial context with a 'local' cueing paradigm consisting of geometric symbols placed on the extremities of the lines. The performance between heal...

journal_title：Neuroreport

authors： Michel C,Bidot S,Bonnetblanc F,Quercia P

更新日期：2011-01-26 00:00:00

abstract：:Previous event-related potential studies in Indo-European languages reported a surprising finding that failed syntactic category processing appears to block lexical-semantic integration, suggesting a functional primacy of syntax over semantics. An event-related potential experiment was conducted to test whether there ...

journal_title：Neuroreport

authors： Yu J,Zhang Y

更新日期：2008-05-07 00:00:00

abstract：:Inconsistencies in previous attempts to localize the N2 wave in the GO/NOGO task led to the present investigation. The inconsistencies were probably because of heterogeneity of psychological operations involved in GO/NOGO tasks. We applied the independent component analysis to a collection of individual event-related ...

journal_title：Neuroreport

authors： Kropotov JD,Ponomarev VA

更新日期：2009-12-09 00:00:00

abstract：:Cerebral blood flow (CBF) was measured at varying haematocrit values in 8 streptozotocin-diabetic and in 7 control rats using the intracarotid 133Xe technique. A hyperbolic relationship between CBF and haematocrit was established for the individual rats in both groups. Diabetic animals showed a preserved CBF response ...

journal_title：Neuroreport

authors： Knudsen GM,Tedeschi E,Jakobsen J

更新日期：1992-11-01 00:00:00