Abstract:
:Blood oxygen level dependent MRI was used to test whether cocaine-stimulated mesolimbic activity varied with sexual receptivity. Rats were randomly screened for lordotic responses and were then imaged for their responses to centrally administered cocaine. We observed that female rats expressing no lordosis showed a greater activation of mesolimbic and nigrostriatal structures than lordotic female rats. Our data suggest that the differential sensitivity to cocaine occurs not only as a result of hormonal changes of the estrous cycle, but also in association with changes in sexual receptivity.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Febo M,Segarra AC,Stolberg TL,Ferris CFdoi
10.1097/WNR.0b013e3283416f81subject
Has Abstractpub_date
2011-01-05 00:00:00pages
19-22issue
1eissn
0959-4965issn
1473-558Xjournal_volume
22pub_type
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