Regenerating adult rat retinal axons reconnect with target neurons in-vitro.

Abstract:

:We have established an in-vitro coculture-system of adult rat retina with fetal midbrain explants to examine whether regenerating central nervous system axons are still able to recognize appropriate target neurons. Our results show that the retinal ganglion cell axons regenerate their axons and reinnervate the retino-recipient areas of cocultured fetal midbrain slices after one to seven weeks in-vitro. Functional connections as defined by electrophysiological criteria are detected only within these areas.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Bähr M,Eschweiler GW

doi

10.1097/00001756-199110000-00007

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

581-4

issue

10

eissn

0959-4965

issn

1473-558X

journal_volume

2

pub_type

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