Opioid receptor independent inhibition of Ca2+ and K+ currents in NG108-15 cells by the kappa opioid receptor agonist U50488H.

abstract：:Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis. We presently evaluated neural progenitor proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus, subventricular zone, and the posterior periventricle in the brains of IL-6 knockout mice and their wild-type l...

journal_title：Neuroreport

authors： Bowen KK,Dempsey RJ,Vemuganti R

更新日期：2011-02-16 00:00:00

abstract：:Investigating activity-dependent plasticity in the auditory brain stem of the adult rat, we observed that electrical intracochlear stimulation led to a tonotopically localized modulation of the phosphorylation of the cAMP response element binding protein (CREB) and an equally localized expression of the immediate earl...

journal_title：Neuroreport

authors： Illing RB,Michler SA

更新日期：2001-03-26 00:00:00

abstract：:Focal lesions of the visual cortex induce deafferentiation, excitotoxic cell death as well as functional reorganization in the surrounding tissue. The intracellular second messenger calcium is involved in a wide range of cellular responses including excitotoxicity and functional reorganization following cortical injur...

journal_title：Neuroreport

authors： Barmashenko G,Eysel UT,Mittmann T

更新日期：2001-10-08 00:00:00

abstract：:In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...

journal_title：Neuroreport

authors： Yamada S,Nomura T,Takano K,Fujita S,Miyake M,Miyake J

更新日期：2008-11-19 00:00:00

abstract：:24S-hydroxycholesterol, the primary oxidation product of cholesterol in the brain, plays a key role in cholesterol elimination and homeostasis. While the concentration of this neurotoxic oxysterol decreases with age, 24S-hydroxycholesterol is elevated in Alzheimer's disease. In this study, we examined the effects of 2...

journal_title：Neuroreport

authors： Alexandrov P,Cui JG,Zhao Y,Lukiw WJ

更新日期：2005-06-21 00:00:00

abstract：:The interaction of vestibular inputs with different dynamic and spatial behavior, i.e., canal-otolith interaction, leads to spatio-temporal convergence. Vestibular neurons in the fastigial nucleus often exhibit spatio-temporal convergence. The present report demonstrates that the discharge rates of most vestibular neu...

journal_title：Neuroreport

authors： Wilden A,Glasauer S,Kleine JF,Büttner U

更新日期：2002-05-07 00:00:00

abstract：:Physical exercise has many health benefits, including improved cardiovascular fitness, lean muscle development, increased metabolism, and weight loss, as well as positive effects on brain functioning and cognition. Recent evidence suggests that regular physical exercise may also affect the responsiveness of reward reg...

journal_title：Neuroreport

authors： Killgore WD,Kipman M,Schwab ZJ,Tkachenko O,Preer L,Gogel H,Bark JS,Mundy EA,Olson EA,Weber M

更新日期：2013-12-04 00:00:00

abstract：:Prior work has shown that kappa opioids may attenuate the effects of analgesic mu receptor agonists in some neural circuits related to pain modulation. This study examined whether hypoalgesia following exposure to a signal for shock is attenuated by infusions of the kappa agonist U69593 into the rostral ventromedial m...

journal_title：Neuroreport

authors： Foo H,Helmstetter FJ

更新日期：2000-10-20 00:00:00

abstract：:Maintenance of long-term potentiation in perforant path-granule cell synapses is accompanied by increased glutamate release. Here we investigate the role of synaptophysin in release and in expression of long-term potentiation in dentate gyrus. We report that long-term potentiation was accompanied by increased endogeno...

journal_title：Neuroreport

authors： Mullany PM,Lynch MA

更新日期：1998-08-03 00:00:00

abstract：:Demyelinated CNS axons can be remyelinated by Schwann cells. A recent study concluded that with time Schwann cell remyelination is replaced by oligodendrocyte remyelination [9]. To examine this, the extent of Schwann cell and oligodendrocyte remyelination at 4, 6.5 and 24 weeks was determined for ethidium bromide lesi...

journal_title：Neuroreport

authors： Gilson JM,Blakemore WF

更新日期：2002-07-02 00:00:00

abstract：:This study was carried out based on the assumption that brain-derived neurotrophic factor (BDNF) may counterbalance the action of morphine in the brain. Morphine analgesic tolerance after daily administrations for six days was blocked by intracerebroventricular injection of anti-BDNF IgG on day 5, but not by administr...

journal_title：Neuroreport

authors： Matsushita Y,Ueda H

更新日期：2009-01-07 00:00:00

abstract：:In order to accomplish desired movements, the nervous system must specify the movement dynamics: it must provide a signal that compensates for the mechanical constraints encountered during movement. Here we tested whether the population activity of Purkinje cells in the cerebellum specifies the dynamics for pursuit ey...

journal_title：Neuroreport

authors： Krauzlis RJ

更新日期：2000-04-07 00:00:00

abstract：:A fundamental issue in neuronal and glial cells is how intracellular rises in Ca2+ are coupled to signaling cascades and changes in subcellular morphology. We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS. Here, we demonstrate the pr...

journal_title：Neuroreport

authors： Clemen CS,Herr C,Lie AA,Noegel AA,Schröder R

更新日期：2001-05-08 00:00:00

abstract：:The distribution of neurones expressing neuropeptide Y (NPY) mRNA in the brain of the goldfish was investigated using a non-radioactive in situ hybridization technique. Neurones expressing NPY mRNA were located in cell groups previously shown to exhibit NPY immunoreactivity in the ventral telencephalon, thalamus, opti...

journal_title：Neuroreport

authors： Vecino E,Perez MT,Ekström P

更新日期：1994-12-30 00:00:00

abstract：:We investigated the age-related change in the distribution of a molecular marker for neural stem and precursor cells, Musashi-1, in the olfactory epithelium of mice from 1 day up to 16 months of age using immunohistochemistry. We also compared the distribution pattern of Musashi-1 with that of growth-associated protei...

journal_title：Neuroreport

authors： Watanabe K,Kondo K,Takeuchi N,Okano H,Yamasoba T

更新日期：2007-05-07 00:00:00

abstract：:To observe sequential stages in tactile pattern discrimination and their modification with and without attention, we used whole-head anatomically constrained magnetoencephalography to spatiotemporally map brain responses. Eight, normal, right-handed participants discriminated between two patterns presented on the palm...

journal_title：Neuroreport

authors： Reed CL,Hagler DJ Jr,Marinkovic K,Dale A,Halgren E

更新日期：2009-07-01 00:00:00

abstract：:The present study examined species differences in spatial and non-spatial memory in the Morris water maze. Male Wistar rats and C57BL/6 mice were tested in a one-day water maze task in which spatial learning, retention, and non-spatial learning were assessed within 3 h. Rats and mice appeared to use different strategi...

journal_title：Neuroreport

authors： Frick KM,Stillner ET,Berger-Sweeney J

更新日期：2000-11-09 00:00:00

abstract：:In a previous event-related fMRI study, we showed that the left occipitotemporal cortex was specifically involved in the abstract categorization of visually presented alphabetic symbols. Here, we duplicate the fMRI study by measuring visual event-related potentials to verify whether the left posterior cortex supports ...

journal_title：Neuroreport

authors： Gros H,Doyon B,Rioual K,Celsis P

更新日期：2002-06-12 00:00:00

abstract：:Sulphated cholecystokinin-8 (CCK-8) given into the neostriatum of the rat by in vivo microdialysis produced a concentration-dependent (1-100 microM) increase in extracellular aspartate (Asp) and dynorphin B (Dyn B), but not in glutamate, GABA or dopamine levels. The increase in Asp levels produced by 10 microM CCK-8 w...

journal_title：Neuroreport

authors： You ZB,Pettersson E,Herrera-Marschitz M,Hökfelt T,Terenius L,Nylander I,Goiny M,Hughes J,O'Connor WT,Ungerstedt U

更新日期：1994-11-21 00:00:00

abstract：:In this study, we ask whether or not the involuntary capture of attention by a specific information type can produce domain-specific activation. Participants indicated the presence of a flicker in rapidly alternating letter-string masks presented in the periphery. Despite letters not being relevant to the task, we fou...

journal_title：Neuroreport

authors： Finkbeiner M,Slotnick SD,Moo LR,Caramazza A

更新日期：2007-07-02 00:00:00

abstract：:Melatonin has been shown to exert potent antinociception but the sites and mechanisms of action underlying this effect have not yet been clarified. The effect of melatonin on spinal cord nociceptive transmission was studied in rats by assessing wid-up activity in a C-fiber reflex responses paradigm evoked by repetitiv...

journal_title：Neuroreport

authors： Laurido C,Pelissie T,Soto-Moyano R,Valladares L,Flores F,Hernández A

更新日期：2002-01-21 00:00:00

abstract：:The present study was based on earlier findings that the observation of a coherently moving long bar induced gamma-band activity in humans. The power in the EEG-gamma-band was reduced during the presentation of two incoherently moving short bars. The present study demonstrates the replicability of this cortical activi...

journal_title：Neuroreport

authors： Müller MM,Junghöfer M,Elbert T,Rochstroh B

更新日期：1997-07-28 00:00:00

abstract：:When we look at our spatial environment we have the feeling that the whole visual field is coloured, yet the density of cone photoreceptors decreases considerably as eccentricity increases. We investigated colour perception (coloured/noncoloured), colour naming and whether colour helps object recognition at eccentrici...

journal_title：Neuroreport

authors： Naïli F,Despretz P,Boucart M

更新日期：2006-10-23 00:00:00

abstract：:To analyze an auditory scene, the segregation of the input into separate streams of information is necessary. Here, the mismatch negativity (MMN) of the event-related potential was used to trace the number of simultaneously monitored streams in auditory scene analysis. Subjects passively listened to sounds belonging t...

journal_title：Neuroreport

authors： Nager W,Teder-Sälejärvi W,Kunze S,Münte TF

更新日期：2003-05-06 00:00:00

abstract：:We investigated the detection of rare task-irrelevant changes in the lexical status of speech stimuli. Participants performed a nonlinguistic task on word and pseudoword stimuli that occurred, in separate conditions, rarely or frequently. Task performance for pseudowords was deteriorated relative to words, suggesting ...

journal_title：Neuroreport

authors： Muller-Gass A,Roye A,Kirmse U,Saupe K,Jacobsen T,Schröger E

更新日期：2007-10-29 00:00:00

abstract：:Increased expression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are early, critical events in several forms of apoptosis. In order to investigate the subcellular trafficking of GAPDH in vivo, the localization of a GAPDH-green fluorescent protein (GFP) fusion was studied in PC12, HEK 2...

journal_title：Neuroreport

authors： Shashidharan P,Chalmers-Redman RM,Carlile GW,Rodic V,Gurvich N,Yuen T,Tatton WG,Sealfon SC

更新日期：1999-04-06 00:00:00

abstract：:Brain activation of 11 healthy right-handed subjects was studied with magnetoencephalography to estimate individual hemispheric dominance for speech sounds. The auditory stimuli comprised binaurally presented Finnish vowels, tones, and piano notes in groups of two or four stimuli. The subjects were required to detect ...

journal_title：Neuroreport

authors： Gootjes L,Raij T,Salmelin R,Hari R

更新日期：1999-09-29 00:00:00

abstract：:Stimulation of the Schaffer collateral projection to the CA1 region in rat hippocampal slices at 1 Hz for 15 min produced a N-methyl-D-aspartate (NMDA) receptor-dependent long-term depression (LTD) of synaptic responses and, when given after tetanic stimulation, reversed long-term potentiation (LTP). Both LTD and the ...

journal_title：Neuroreport

authors： Izumi Y,Zorumski CF

更新日期：1993-09-01 00:00:00

abstract：:Following brain injury astrocytes swell acutely and proliferate thereafter. To investigate the direct relationship between swelling and proliferation, cultured astroglial cells were exposed to 60 mM K+ ion or hypo-osmolar (205 mOsm) electrolyte solution for 1 h to cause transient swelling. Proliferation was assessed b...

journal_title：Neuroreport

authors： Del Bigio MR,Omara F,Fedoroff S

更新日期：1994-01-31 00:00:00

abstract：:The relation between neuronal activity in the superior parietal lobule with working memory capacity in an elderly population was investigated. Using functional magnetic resonance imaging we examined effects associated with the performance of a reading span test and individual differences in executive function and shor...

journal_title：Neuroreport

authors： Otsuka Y,Osaka N,Osaka M

更新日期：2008-09-17 00:00:00