Abstract:
:The terrestrial snail Helix lucorum is a promising model for molecular neurobiology since its central nervous system (CNS) is simple and contains many morphologically and functionally identified large neurones. Among these, the giant interneurones located in pleural and parietal ganglia are especially interesting because they trigger the withdrawal behaviour of the snail and participate in aversive conditioning. Here we describe the identification and characterization of a gene named HCS1 which is preferentially expressed in these interneurones. It encodes a putative protein 100 amino acids long containing an N-terminal hydrophobic leader peptide. No sequences with significant homology to HCS1 were found in the protein (Swiss-Prot) and nucleotide (EMBLbank) data libraries. We suppose that the product of this gene is a secreted protein, presumably a neuropeptide or a growth factor.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Bogdanov YD,Ovchinnikov DA,Balaban PM,Belyavsky AVdoi
10.1097/00001756-199401000-00014subject
Has Abstractpub_date
1994-01-31 00:00:00pages
589-92issue
5eissn
0959-4965issn
1473-558Xjournal_volume
5pub_type
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