Abstract:
:The present study was performed to examine how intention to learn and explicit knowledge in sequence learning are reflected in event-related potentials. Participants responded to numerals presented in a repeating order, which were replaced infrequently by deviant numerals. The participants were given incidental or intentional learning instructions. Sequence parts for which they acquired explicit knowledge were identified for each participant by post-task memory tests. Reaction times indicated that sequence learning occurred under both types of instruction. The N2 enhancement for deviants was primarily associated with explicit sequence knowledge, and the P3 enhancement showed a weak association. These results suggested that N2 and P3 reflect different aspects of explicit learning.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Miyawaki K,Sato A,Yasuda A,Kumano H,Kuboki Tdoi
10.1097/00001756-200505120-00010subject
Has Abstractpub_date
2005-05-12 00:00:00pages
705-8issue
7eissn
0959-4965issn
1473-558Xpii
00001756-200505120-00010journal_volume
16pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::When we perform a visually guided reaching action, the brain coordinates our hand and eye movements. Eye-hand coordination has been examined widely, but it remains unclear whether the hand and eye motor systems are coordinated during on-line visuomotor adjustments induced by a target jump during a reaching movement. A...
journal_title:Neuroreport
pub_type: 杂志文章,随机对照试验
doi:10.1097/WNR.0000000000000111
更新日期:2014-05-07 00:00:00
abstract::One mechanism thought to mediate hand and upper limb control across motor cortices is called interhemispheric inhibition (IHI). Somatosensory cortices are important in the motor control of the hand, although the neural mechanisms by which somatic loci act are not fully understood. In the present study, we study the po...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32836131ca
更新日期:2013-05-08 00:00:00
abstract::We earlier showed that leucine-rich glioma inactivated 3 (LGI3) colocalizes with amyloid beta peptide (Abeta) taken up by astrocytes both in vitro and in vivo, and that LGI3 accumulated with endocytosis-associated proteins in aged monkey brains. In this study, we confirmed that LGI3 localizes to the endocytic pathway ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32830a4cc4
更新日期:2008-08-06 00:00:00
abstract::The potential neuroprotective effects of glial cell line-derived neurotrophic factor (GDNF) and neublastin (NBN) against NMDA-induced excitotoxicity were examined in hippocampal brain slice cultures. Recombinant human GDNF (25-100 ng/ ml) or NBN, in medium conditioned by growth of transfected, NBN-producing HiB5 cells...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200012180-00032
更新日期:2000-12-18 00:00:00
abstract::The pathogenesis of amyotrophic lateral sclerosis remains poorly understood, but microglial and astroglial activation are thought to contribute to motor neuron death. Evidence suggests that matrix metalloproteinase-9 (MMP-9) is a mediator of this deleterious effect. In this study, we evaluated the effect of MMP-9 on t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200503150-00003
更新日期:2005-03-15 00:00:00
abstract::In several central nervous system neuronal populations, axotomy triggers the upregulation of regeneration-associated genes such as c-Jun, which determines neurons ability to regenerate axon in a growth-permissive environment. We analyzed the expression of c-Jun in rat ventral medullary neurons after cervical hemisecti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000179075.32035.0f
更新日期:2005-09-28 00:00:00
abstract::Direct application of brain-derived neurotrophic factor (BDNF) to the cut end of axotomized immature motor neurones had only transient survival-promoting effects. Therefore, we have examined whether additional delivery of BDNF with repeated subcutaneous injections (1 mg/ml) could potentiate this short-term rescue of t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199410000-00012
更新日期:1994-10-03 00:00:00
abstract::Both ice-like protease and calpain have been shown to be involved in apoptosis in non-neuronal cells. Cultured rat cerebellar granule neurons undergo apoptosis when exposed to low potassium-containing medium. Calpain inhibitors 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid (PD150606) and N-acetyl-Leu-Leu-Met-CHO (c...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199612200-00050
更新日期:1996-12-20 00:00:00
abstract::High-resolution (< 50 microm) magnetic resonance imaging microscopy (MRM) has been used to identify brain regions and localization of excitotoxin-induced lesions in fixed rat brains, subsequently confirmed using standard histology. The anatomical extent of lesions identified by MRM was identical to that seen in histol...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199903170-00014
更新日期:1999-03-17 00:00:00
abstract::Voltage-dependent outward currents were examined in CA1 neurones by whole-cell recording in slices. Nine cells were recorded with the 'standard' internal solution (KMeSO4, HEPES, EGTA, CaCl2, and MgCl2) and held a potential (-54 +/- 3 mV) at which there was no significant outward current. Cromakalim (CROM, 100 microM)...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1994-06-27 00:00:00
abstract::A tritiated specific and highly potent 5-HT4 antagonist: [3H]-GR113808 was used to label specific binding sites in human brain and for comparison in guinea-pig brain. [3H]-GR113808 association and dissociation were rapid, the binding was saturable and displaced by various serotoninergic agents with an affinity corresp...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199309000-00007
更新日期:1993-09-10 00:00:00
abstract::According to the previous research, metformin, a medication utilized for type 2 diabetes management, inhibits neural aging and reduces infarct size by enhancing angiogenesis in a mouse stroke model. What is more, metformin administration also promotes neural precursor cells proliferation, migration, as well as differe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000001190
更新日期:2019-02-06 00:00:00
abstract::The present study used scores from Seligman's Attribution Style Questionnaire and [15O] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-sna...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200106130-00024
更新日期:2001-06-13 00:00:00
abstract::We report the results of serial transcranial magnetic stimulation mapping of cortical motor outputs to the face and upper extremity in a subject studied before and repeatedly after traumatic amputation of the right arm immediately below the elbow. The results of the mapping studies illustrate the time course of plasti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199609020-00002
更新日期:1996-09-02 00:00:00
abstract::We recently reported behavioral improvements following intrastriatal transplantation of cryopreserved cultured human neuroteratocarcinoma-derived cells (hNT neurons) in rats with cerebral ischemia induced by occlusion of the middle cerebral artery. In the present study, the viability and survival of hNT neurons were e...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199808240-00028
更新日期:1998-08-24 00:00:00
abstract::Prism adaptation reduces some symptoms of neglect; however the mechanisms underlying such changes are poorly understood. We suggest that prisms influence neglect by acting on dorsal stream circuits subserving visuomotor control, with little influence on perceptual aspects of neglect. We examined prism adaptation in th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328338592f
更新日期:2010-04-21 00:00:00
abstract::A previous investigation has suggested that the hyperpolarization-activated cation current Ih does not contribute to the spontaneous firing of midbrain dopaminergic neurons. This conclusion was reached using Cs(-1). We have re-examined this question with extracellular recordings in slices using the more specific block...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200102120-00015
更新日期:2001-02-12 00:00:00
abstract::This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the time of ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199611040-00048
更新日期:1996-11-04 00:00:00
abstract::An anti-leptin polyclonal antiserum was used to detect leptin-immunoreactivity (-ir) in the central nervous system in rats. Leptin-ir was found in perikaryon and processes of neurons in the hypothalamus, including the paraventricular nucleus, and in several regions in the brainstem, including the nucleus of the solita...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199902050-00042
更新日期:1999-02-05 00:00:00
abstract::PEC-60, a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor, has been isolated, characterized and molecularly cloned. It shows biological activity as a hormone in both the gastrointestinal tract and in the immune system. We now report immunohistochemical evidence ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199409080-00033
更新日期:1994-09-08 00:00:00
abstract::It is widely accepted that prostaglandin (PG) E2 is the principal pro-inflammatory prostanoid and plays an important role in inflammatory pain. However whether PGE2 is involved in neuropathic pain remains unknown. PGE2 is produced from arachidonic acid via PGH2 by at least three PGE synthases (PGES), cytosolic PGES (c...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000129372.89000.31
更新日期:2004-06-28 00:00:00
abstract::Experiments using chimeric stimuli have shown that the right hemisphere is more influential in processing facial information. Here, again, we found clear evidence that study participants used the information from the left side of the face to inform their gender decisions when chimeric male/female, female/male stimuli ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200512190-00004
更新日期:2005-12-19 00:00:00
abstract::Prior research with rodent models, performed predominantly in males, has demonstrated a significant association between focal neocortical malformations (e.g. ectopias and microgyria) and rate-specific auditory processing deficits. In the current study and consistent with prior findings, we report that ectopic male BXS...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200212030-00021
更新日期:2002-12-03 00:00:00
abstract::Glutamatergic excitotoxicity has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, activation of metabotropic glutamate receptors (mGluRs) is neuroprotective in several paradigms. We therefore tested the effect of selective mGluR agonists on cultured chick embryonic motor neurons. Ac...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199806220-00024
更新日期:1998-06-22 00:00:00
abstract::In situ hybridization was used to localize mRNA encoding two cooperative serine/threonine kinase receptors. Activin receptor IIA mRNA in the adult rat brain is highly expressed in the dentate gyrus, in the pyramidal neurones of CA3 and CA1, in the entorhinal cortex, in the cortical amygdaloid nucleus and in the amygda...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1995-12-29 00:00:00
abstract::We examined the biology of AMPA/kainate-induced motor neuron degeneration using dissociated spinal cord cultures and motor neuron-specific antibodies which enable characterization of individual motor neurons in culture. Cobalt, which is thought to pass through Ca2+-permeable AMPA/kainate receptors following kainate ex...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199903170-00034
更新日期:1999-03-17 00:00:00
abstract::Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175613.16183.6c
更新日期:2005-08-22 00:00:00
abstract::It is well known that perceiving another person's body movements activates corresponding motor representations in an observer's brain, a process which appears to be imitative in nature. However, it is also true that simply imitating another person's action/s in many situations is not an effective or appropriate respon...
journal_title:Neuroreport
pub_type: 杂志文章,评审
doi:10.1097/WNR.0b013e3283630a66
更新日期:2013-08-07 00:00:00
abstract::Pharmacological manipulation of brain dopamine concentration affects visuospatial working memory in humans and in animals, the latter effects localized to the prefrontal cortex. However, the effects of dopamine agonists on humans are poorly understood. We hypothesized that bromocriptine would have an effect on cogniti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199711100-00032
更新日期:1997-11-10 00:00:00
abstract::CEP-1347 inhibits the signalling pathway of c-jun-N-terminal kinase, and is neuroprotective in vivo and in vitro. Embryonic chick dorsal root ganglion neurones are dependent on NGF for survival and neurite outgrowth; NGF withdrawal results in apoptotic cell death. We examined the neuroprotective and neurite outgrowth ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000070828.57864.ad
更新日期:2003-05-23 00:00:00