Ca(2+)-sensitive and insensitive omega-conotoxin GVIA binding sites in rat brain.

abstract：:Axonal atrophy may reflect earlier and more reversible events in neurodegeneration and ageing than somatic atrophy. Innervation density by sympathetic fibres from the rat superior cervical ganglion (SCG) to the middle cerebral artery (MCA) decreases dramatically in old age, while that to the iris is largely unchanged....

journal_title：Neuroreport

authors： Kuchel GA,Poon T,Irshad K,Richard C,Julien JP,Cowen T

更新日期：1997-02-10 00:00:00

abstract：:Human somatosensory evoked potentials (SEP) contain high-frequency (600 Hz) wavelet bursts possibly reflecting repetitive population spikes in thalamocortical axons and/or postsynaptic responses. To dissociate thalamic and cortical burst components the recovery of intrathalamic SEP (derived from electrodes implanted f...

journal_title：Neuroreport

authors： Klostermann F,Funk T,Vesper J,Siedenberg R,Curio G

更新日期：2000-04-27 00:00:00

abstract：:Blockade of L-type Ca2+ channels results in a decrease in firing frequency of neostriatal neurons. In contrast, N- and P/Q-types of Ca2+ channel cooperate to tune firing pattern, since both of these channel types have to be blocked to enhance firing frequency. Parameters of the intensity-frequency plot were differenti...

journal_title：Neuroreport

authors： Pérez-Garci E,Bargas J,Galarraga E

更新日期：2003-07-01 00:00:00

abstract：:Short-latency ocular following responses in monkeys, induced by first- and second-order motion during a fixation task, were sensitive to stimulus size, retinal eccentricity and motion duration. Latency of eye movements was no different for first- or second-order motion and simply marked the occurrence of movement in t...

journal_title：Neuroreport

authors： Benson PJ,Guo K

更新日期：1998-12-01 00:00:00

abstract：:The aim of this study was to investigate the changes in insular cortex metabolites and the correlation with clinical manifestations in patients with obstructive sleep apnea syndrome (OSA). Lateral insular metabolite levels were measured and relevant ratios were calculated in OSA patients and healthy individuals, inclu...

journal_title：Neuroreport

authors： Kang J,Tian Z,Li M

更新日期：2018-08-15 00:00:00

abstract：:The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

journal_title：Neuroreport

authors： O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

更新日期：2000-11-27 00:00:00

abstract：:Reading is a learned skill that is likely influenced by both brain maturation and experience. Functional imaging studies have identified brain regions important for skilled reading, but the structural brain changes that co-occur with reading acquisition remain largely unknown. We investigated maturational volume chang...

journal_title：Neuroreport

authors： Houston SM,Lebel C,Katzir T,Manis FR,Kan E,Rodriguez GG,Sowell ER

更新日期：2014-03-26 00:00:00

abstract：:Event-related potentials(ERPs) were measured while subjects were constructing mental images of a letter of the alphabet. Following presentation of an uppercase letter, subjects were asked to form a mental image of the same letter in lower case, and determine whether or not it had an ascending or descending stroke (asc...

journal_title：Neuroreport

authors： Yamamoto S,Mukai H

更新日期：1998-10-26 00:00:00

abstract：:Pharmacological activation of group III metabotropic glutamate receptors (mGluR) or inhibition of group I mGluR by subtype-selective ligands is neuroprotective in experimental models of Parkinson's disease. The aim of this study was to investigate whether targeting both receptor subtypes simultaneously produces enhanc...

journal_title：Neuroreport

authors： Vernon AC,Croucher MJ,Dexter DT

更新日期：2008-03-05 00:00:00

abstract：:The anxiolytic-like potential of anpirtoline was assessed in a mouse light/dark aversion test. Anpirtoline (1.0 ng kg(-1)-1.0 micrograms kg-1 i.p.) reduced the aversive responding of mice. This was detected as an increase in the latency to locate the non-aversive compartment and by decreases in the percentage of the t...

journal_title：Neuroreport

authors： Metzenauer P,Barnes NM,Costall B,Gozlan H,Hamon M,Kelly ME,Murphy DA,Naylor RJ

更新日期：1992-06-01 00:00:00

abstract：:In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....

journal_title：Neuroreport

authors： Le Van Quyen M,Martinerie J,Baulac M,Varela F

更新日期：1999-07-13 00:00:00

abstract：:Heptylene-linked bis-(9-amino-1,2,3,4-tetrahydroacridine) (bis(7)-tacrine) is a potential palliative therapeutic agent for Alzheimer's disease (AD), on the basis of its superior acetylcholinesterase (AChE) inhibition and memory-enhancing potency relative to tacrine. In this study we report that bis(7)-tacrine exhibits...

journal_title：Neuroreport

authors： Li CY,Wang H,Xue H,Carlier PR,Hui KM,Pang YP,Li ZW,Han YF

更新日期：1999-03-17 00:00:00

abstract：:We used whole-cell recording to identify, for the first time, GABAergic tonic current in subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of the gamma-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49 of 73 substantia gelatinosa neurons. Thes...

journal_title：Neuroreport

authors： Takahashi A,Mashimo T,Uchida I

更新日期：2006-08-21 00:00:00

abstract：:Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...

journal_title：Neuroreport

authors： Machner B,Sprenger A,Kömpf D,Heide W

更新日期：2005-09-08 00:00:00

abstract：:We investigated the effects of 2,2,2-trichloroethanol (TCE), the active metabolite of chloral hydrate, on large-conductance calcium-activated K+ channels (BKCa channels) of dorsal root ganglion (DRG) neurones. In outside-out patches, 2 and 5 mM TCE increased the open probability of BKCa channels to 1.7-fold and 2.8-fo...

journal_title：Neuroreport

authors： Gruss M,Hempelmann G,Scholz A

更新日期：2002-05-07 00:00:00

abstract：:Neuronal interferon-gamma (N-IFN-gamma), recently isolated from the nervous system, has a molecular weight distinct from that of lymphocyte-derived IFN-gamma, but crossreacts immunologically and shares certain bioactivities with this cytokine. In the rat brain N-IFN-gamma-immunoreactive perikarya were concentrated in ...

journal_title：Neuroreport

authors： Bentivoglio M,Florenzano F,Peng ZC,Kristensson K

更新日期：1994-12-20 00:00:00

abstract：:Amyloid plaques and neurofibrillary tangles are the major pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles are composed of filaments and paired helical filaments containing polymerized hyperphosphorylated tau protein. Derlin proteins are a family of proteins that are conserved in all eukaryotes, ...

journal_title：Neuroreport

authors： Honjo Y,Ito H,Horibe T,Shimada H,Nakanishi A,Mori H,Takahashi R,Kawakami K

更新日期：2012-07-11 00:00:00

abstract：:Retinal ganglion cells of the fish have the spontaneous capacity to regenerate after nerve crush, a phenomenon known to be facilitated by nerve growth factor (NGF). We have studied the high-affinity NGF receptor TrkA, during the regeneration of the tench (Tinca tinca L.) optic nerve, using immunocytochemical technique...

journal_title：Neuroreport

authors： Vecino E,Caminos E,Becker E,Rudkin BB,Evan GI,Martín-Zanca D

更新日期：1998-10-26 00:00:00

abstract：:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus...

journal_title：Neuroreport

authors： Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S

更新日期：1998-04-20 00:00:00

abstract：:Functional imaging has struggled for two decades to establish a quantitative link between the neuronal activity and the change in signal obtained. This review proposes a division of neuronal activity into a component relating to the electrical discharge activity and a component relating to the size of the activated ne...

journal_title：Neuroreport

authors： Marcar VL,Loenneker T

更新日期：2004-09-15 00:00:00

abstract：:Animal studies have shown brain ischaemia to cause oxidative damage to DNA and activation of caspase-3, leading to apoptosis. These changes may be exacerbated by reperfusion. To assess caspase-3 activation after transient and permanent brain ischaemia in man, we examined brain tissue from patients who had experienced ...

journal_title：Neuroreport

authors： Love S,Barber R,Srinivasan A,Wilcock GK

更新日期：2000-08-03 00:00:00

abstract：:Using a guessing paradigm we measured visual sensitivity in the blind and normal half-fields of four cerebrally hemidecorticated patients. In the blind field, sensitivity was reduced by approximately 3 long units. Stimuli which produced significant detection also evoked conscious sensations of light and colour. Contro...

journal_title：Neuroreport

authors： Stoerig P,Faubert J,Ptito M,Diaconu V,Ptito A

更新日期：1996-08-12 00:00:00

abstract：:Magnetic brain responses were recorded to clarify the cortical representation of vowel processing in Japanese. We investigated the peak latencies and equivalent current dipoles of the auditory N1m responses to the Japanese vowels [a], [i], [o], and [u]. In intraindividual analyses for a single participant, well-replic...

journal_title：Neuroreport

authors： Ogata E,Yumoto M,Itoh K,Sekimoto S,Karino S,Kaga K

更新日期：2006-07-31 00:00:00

abstract：:The transmissible spongiform encephalopathies (TSEs) invariably result in fatal neurodegeneration and accumulation of PrP, an abnormal form of the host prion protein PrP, encoded by the PRNP gene. A naturally occurring polymorphism (methionine/valine) at PRNP codon 129 is associated with variation in relative disease ...

journal_title：Neuroreport

authors： O'Rourke KI,Spraker TR,Zhuang D,Greenlee JJ,Gidlewski TE,Hamir AN

更新日期：2007-12-03 00:00:00

abstract：:Neonatal peripheral inflammation has been shown to alter the neural circuitry of the spinal cord in adult rats. However, the temporal and spatial changes in the distribution of primary afferent terminals immediately following a neonatal inflammatory stimulus remains unclear. In the present study we found that intrapla...

journal_title：Neuroreport

authors： Ling QD,Chien CC,Wen YR,Fu WM,Sun WZ

更新日期：2003-10-27 00:00:00

abstract：:Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation of BMMCs is considered a potential approach to promoting the repair of ischemic damaged organs. H...

journal_title：Neuroreport

authors： Takagi T,Yoshida T,Okada M,Hata R,Hato N,Gyo K,Hakuba N

更新日期：2014-08-06 00:00:00

abstract：:The tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 is expressed only in nociceptive sensory neurons. This channel has been proposed to contribute significantly to the sensitization of primary sensory neurons after injury. We have studied the nociceptive behaviours of mice carrying a null mutation in the N...

journal_title：Neuroreport

authors： Kerr BJ,Souslova V,McMahon SB,Wood JN

更新日期：2001-10-08 00:00:00

abstract：:There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to the level of sentence syntax. Although birdsong can indeed have a complex structure, it lacks the combinatori...

journal_title：Neuroreport

authors： Beckers GJ,Bolhuis JJ,Okanoya K,Berwick RC

更新日期：2012-02-15 00:00:00

abstract：:Administration of either a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801 (dizocilpine), or a muscarinic antagonist, scopolamine, produces dose-related impairments in performance of a visual recognition memory task, delayed non-matching to sample (DNMS) with lists of 20 symbols, in rhesus monk...

journal_title：Neuroreport

authors： Matsuoka N,Aigner TG

更新日期：1996-01-31 00:00:00

abstract：:Distracted driving remains a leading factor in fatal motor vehicle crashes, particularly in young drivers. Due to ongoing neuromaturation, attention capabilities are changing and improving throughout young adulthood. Here, we sought to bridge neuroscience with driving simulation by evaluating the effects of driving on...

journal_title：Neuroreport

authors： Banz BC,Wu J,Camenga DR,Mayes LC,Crowley MJ,Vaca FE

更新日期：2020-05-22 00:00:00