Abstract:
:When a food is eaten to satiety, its reward value decreases. This decrease is usually greater for the food eaten to satiety than for other foods, an effect termed sensory-specific satiety. In an fMRI investigation it was shown that for a region of the orbitofrontal cortex the activation produced by the odour of the food eaten to satiety decreased, whereas there was no similar decrease for the odour of a food not eaten in the meal. This effect was shown both by a voxel-wise SPM contrast (p <0.05 corrected) and an ANOVA performed on the mean percentage change in BOLD signal in the identified clusters of voxels (p <0.006). These results show that activation of a region of the human orbitofrontal cortex is related to olfactory sensory-specific satiety.
journal_name
Neuroreportjournal_title
Neuroreportauthors
O'Doherty J,Rolls ET,Francis S,Bowtell R,McGlone F,Kobal G,Renner B,Ahne Gdoi
10.1097/00001756-200003200-00046subject
Has Abstractpub_date
2000-03-20 00:00:00pages
893-7issue
4eissn
0959-4965issn
1473-558Xjournal_volume
11pub_type
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