fMRI of human somatosensory and cingulate cortex during painful electrical nerve stimulation.

abstract：:Both acute and chronic exercise is consistently associated with a number of benefits to physical and mental health, including cardiovascular function, body weight, mood, and cognition. Near-infrared spectroscopy is an ideal method to measure changes in oxygenated and deoxygenated hemoglobin (O2Hb and dHb) levels in th...

journal_title：Neuroreport

authors： Giles GE,Brunyé TT,Eddy MD,Mahoney CR,Gagnon SA,Taylor HA,Kanarek RB

更新日期：2014-11-12 00:00:00

abstract：:Menthol is known as an agonist for cold-sensitive transient receptor potential channels (TRPM8) and also as a direct modulator of GABA channels. We examined the effects of menthol on respiratory rhythm generation in the brainstem-spinal cord preparations isolated from newborn rats. Menthol decreased respiratory rhythm...

journal_title：Neuroreport

authors： Tani M,Onimaru H,Ikeda K,Kawakami K,Homma I

更新日期：2010-12-08 00:00:00

abstract：:Mutations in the presenilin genes are involved in the aetiology of the majority of familial early-onset Alzheimer disease (AD) cases. Presenilin 1 (PS1) is proteolytically processed in vivo, resulting in the accumulation of N-terminal approximately 27-28 kDa and C-terminal approximately 18 kDa derivatives. To examine ...

journal_title：Neuroreport

authors： Hendriks L,Thinakaran G,Harris CL,De Jonghe C,Martin JJ,Sisodia SS,Van Broeckhoven C

更新日期：1997-05-06 00:00:00

abstract：:Previous studies using magnetoencephalographic (MEG) recordings have revealed neuronal populations responding to discrete auditory stimuli in the supratemporal cortex of the human brain. We used the novel whole-head magnetometer (Neuromag-122) to determine whether regions outside the auditory cortex are activated by a...

journal_title：Neuroreport

authors： Lavikainen J,Huotilainen M,Pekkonen E,Ilmoniemi RJ,Näätänen R

更新日期：1994-12-30 00:00:00

abstract：:The ability to attribute mental states to others ('theory of mind') pervades normal social interaction and is impaired in autistic individuals. In a previous positron emission tomography scan study of normal volunteers, performing a 'theory of mind' task was associated with activity in left medial prefrontal cortex. W...

journal_title：Neuroreport

authors： Happé F,Ehlers S,Fletcher P,Frith U,Johansson M,Gillberg C,Dolan R,Frackowiak R,Frith C

更新日期：1996-12-20 00:00:00

abstract：:Brief tetanic stimulation of parallel fibres can evoke a slow excitatory postsynaptic potential (EPSP) in cerebellar Purkinje cells that is mediated by metabotropic glutamate receptors (mGluRs). It is likely that the receptor subtype involved is mGluR1, which couples to the production of diacylglycerol and inositol-1,...

journal_title：Neuroreport

authors： Batchelor AM,Vranesic I,Del Principe F,Garthwaite J,Knöpfel T

更新日期：1996-08-12 00:00:00

abstract：:Reactive gliosis is a prominent morphological feature of temporal lobe epilepsy. The molecular mechanisms underlying glial cell activation remain unclear. We examined expression of Id1-3 protein, a family of helix--loop--helix proteins involved in the regulation of cell proliferation and differentiation, in glial cell...

journal_title：Neuroreport

authors： Aronica E,Vandeputte DA,van Vliet EA,Lopes da Silva FH,Troost D,Gorter JA

更新日期：2001-08-08 00:00:00

abstract：:Following brain injury astrocytes swell acutely and proliferate thereafter. To investigate the direct relationship between swelling and proliferation, cultured astroglial cells were exposed to 60 mM K+ ion or hypo-osmolar (205 mOsm) electrolyte solution for 1 h to cause transient swelling. Proliferation was assessed b...

journal_title：Neuroreport

authors： Del Bigio MR,Omara F,Fedoroff S

更新日期：1994-01-31 00:00:00

abstract：:Neonatal peripheral inflammation has been shown to alter the neural circuitry of the spinal cord in adult rats. However, the temporal and spatial changes in the distribution of primary afferent terminals immediately following a neonatal inflammatory stimulus remains unclear. In the present study we found that intrapla...

journal_title：Neuroreport

authors： Ling QD,Chien CC,Wen YR,Fu WM,Sun WZ

更新日期：2003-10-27 00:00:00

abstract：:Inherited retinal degenerations such as retinitis pigmentosa (RP) are characterized by progressive loss of photoreceptors, apparently by apoptosis, and our recent report of increased secreted Frizzled-related protein-2 (SFRP2) in RP retinas suggests altered Wnt signalling may be a component of the degenerative process...

journal_title：Neuroreport

authors： Jones SE,Jomary C,Grist J,Stewart HJ,Neal MJ

更新日期：2000-12-18 00:00:00

abstract：:We recently reported behavioral improvements following intrastriatal transplantation of cryopreserved cultured human neuroteratocarcinoma-derived cells (hNT neurons) in rats with cerebral ischemia induced by occlusion of the middle cerebral artery. In the present study, the viability and survival of hNT neurons were e...

journal_title：Neuroreport

authors： Borlongan CV,Saporta S,Poulos SG,Othberg A,Sanberg PR

更新日期：1998-08-24 00:00:00

abstract：:Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis. We presently evaluated neural progenitor proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus, subventricular zone, and the posterior periventricle in the brains of IL-6 knockout mice and their wild-type l...

journal_title：Neuroreport

authors： Bowen KK,Dempsey RJ,Vemuganti R

更新日期：2011-02-16 00:00:00

abstract：:Retinal ganglion cells of the fish have the spontaneous capacity to regenerate after nerve crush, a phenomenon known to be facilitated by nerve growth factor (NGF). We have studied the high-affinity NGF receptor TrkA, during the regeneration of the tench (Tinca tinca L.) optic nerve, using immunocytochemical technique...

journal_title：Neuroreport

authors： Vecino E,Caminos E,Becker E,Rudkin BB,Evan GI,Martín-Zanca D

更新日期：1998-10-26 00:00:00

abstract：:This study examined 'prepulse inhibition' in the context of an auditory two-tone discrimination task performed by 15 healthy subjects. In order to distinguish between masking or excitatory information processes, weak acoustic pulses immediately preceded or succeeded a target or non-target tone in the discrimination. B...

journal_title：Neuroreport

authors： Schall U,Ward PB

更新日期：1996-01-31 00:00:00

abstract：:Bulbospinal C1 neurons are sympathoexcitatory and excited by substance P. However the substance P receptor (NK1 receptor), has been reported to be absent from the somata of C1 neurons. In this study, using double and triple labelling immunofluorescence and retrograde tracing, we provide evidence that the NK1 receptor ...

journal_title：Neuroreport

authors： Makeham JM,Goodchild AK,Pilowsky PM

更新日期：2001-12-04 00:00:00

abstract：:Target detection is the process of bringing a salient stimulus into conscious awareness. Target detection evokes a prominent event-related potential (ERP) component (P3) in the electroencephalogram (EEG). We combined the high spatial resolution of functional magnetic resonance imaging (fMRI) with the high temporal res...

journal_title：Neuroreport

authors： Menon V,Ford JM,Lim KO,Glover GH,Pfefferbaum A

更新日期：1997-09-29 00:00:00

abstract：:Oleic acid, a cis-unsaturated free fatty acid, is proposed to be involved in the protein kinase C (PKC) activation pathway. Its biological actions, however, have not been well-characterized. We examined the effects of oleic acid on acetylcholine (ACh)-gated channel currents using Torpedo nicotinic ACh receptors expres...

journal_title：Neuroreport

authors： Nishizaki T,Ikeuchi Y,Matsuoka T,Sumikawa K

更新日期：1997-02-10 00:00:00

abstract：:Dopaminergic neurotransmission is thought to be involved in reward-related incentive learning and addictive behaviour. Amphetamine will alter glycogen synthase kinase-3β (GSK-3β) activity by increasing dopamine transporter efflux rates. We investigated the hypothesis that Wnt signalling will be altered in rat nucleus ...

journal_title：Neuroreport

authors： MacLeod RJ,Moores ME,Beninger RJ

更新日期：2012-10-03 00:00:00

abstract：:Flurothyl kindling initiates a time-dependent process that results in a facilitated propagation from the forebrain to the brainstem seizure system and in an increase in the complexity of behavioral seizure expression. We investigated the involvement of the ventromedial nucleus of the hypothalamus (VMH) in mediating th...

journal_title：Neuroreport

authors： Ferland RJ,Applegate CD

更新日期：1998-11-16 00:00:00

abstract：:Bioelectric activity of CO2-sensitive, ventrolateral medullary neurons (VLN(CS)) in organotypic cultures from the obex level of newborn rats was tested during changes of the intracellular pH (pHi) measured in BCECF-AM loaded cultures. Hypercapnia (pCO2 80-100 mmHg) reduced pHi by 0.15 +/- 0.06 units and stimulated neu...

journal_title：Neuroreport

authors： Wiemann M,Baker RE,Bonnet U,Bingmann D

更新日期：1998-01-05 00:00:00

abstract：:The death of spinal motoneurones after axotomy provides a useful model for studying novel factors which prevent motoneurone loss in vivo. Peripheral nerves of newborn rats were unilaterally transected and treated with either a vehicle solution or leukaemia inhibitory factor (LIF). Compared with the vehicle controls, t...

journal_title：Neuroreport

authors： Cheema SS,Richards LJ,Murphy M,Bartlett PF

更新日期：1994-04-14 00:00:00

abstract：:The distribution of PKCepsilon and its co-localization with various GABA(A) receptor subunits within limbic structures of the mouse brain was examined by fluorescence immunohistochemistry. Levels of PKCepsilon immunoreactivity were highest in the cingulate cortex and dentate gyrus, moderate in the nucleus accumbens, a...

journal_title：Neuroreport

authors： Olive MF,Hodge CW

更新日期：2000-03-20 00:00:00

abstract：:Altered glutamate signaling is associated with Parkinson's disease. To study the involvement of the cystine/glutamate antiporter in the pathogenesis of Parkinson's disease, we developed new polyclonal antibodies recognizing xCT, the specific subunit of this antiporter. The striatal xCT protein expression level was inv...

journal_title：Neuroreport

authors： Massie A,Schallier A,Mertens B,Vermoesen K,Bannai S,Sato H,Smolders I,Michotte Y

更新日期：2008-10-29 00:00:00

abstract：:Internet gaming disorder is defined as excessive and compulsive use of the internet to engage in games that leads to clinically significant psychosocial impairment. We tested the hypothesis that individuals with internet gaming disorder would be less sensitive to high-risk situations and show aberrant brain activation...

journal_title：Neuroreport

authors： Lee D,Lee J,Yoon KJ,Kee N,Jung YC

更新日期：2016-05-25 00:00:00

abstract：:We examined the effect of an AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole) antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F) quinoxaline (NBQX), on rat cerebellar Purkinje cell loss and hippocampal pyramidal CA1 cell loss, after 10 minutes of global cerebral ischemia. NBQX was given intraperitoneally in a do...

journal_title：Neuroreport

authors： Balchen T,Diemer NH

更新日期：1992-09-01 00:00:00

abstract：:Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...

journal_title：Neuroreport

authors： Cho BR,Yoon HS,Kim WY,Vezina P,Kim JH

更新日期：2017-08-02 00:00:00

abstract：:Somatotopic organization of the human medial wall of the cerebral hemispheres was studied using functional MRI conducted at high field strength (3 T) with fine spatial resolution ( approximately 2 mm). Healthy subjects performed paced, repetitive movements of the fingers and toes. Within the supplementary motor area (...

journal_title：Neuroreport

authors： Mayer AR,Zimbelman JL,Watanabe Y,Rao SM

更新日期：2001-12-04 00:00:00

abstract：:Magnetoencephalography (MEG) was used to compare mismatch responses between hemispheres to changes in sound-source direction. Sixteen adults listened passively to two types of complex non-language sounds presented in separate blocks with midline standards and right- and left-lateralized deviants. Mismatch dipole ampli...

journal_title：Neuroreport

authors： Kaiser J,Lutzenberger W,Birbaumer N

更新日期：2000-09-11 00:00:00

abstract：:Reading demands precise and efficient letter and word processing. This event-related potentials (ERP) study utilized massive repetition of visually presented single letters to trigger neuronal adaptation. Our aim was to explore whether the adaptation pattern of the N170 ERP component, serving as an indicator of neuron...

journal_title：Neuroreport

authors： Korinth SP,Sommer W,Breznitz Z

更新日期：2013-01-23 00:00:00

abstract：:Perception of apparent motion operates somewhat differently for objects and human figures. Depending on the interstimulus interval, the latter d may give rise to either perception of a direct path (i.e. biologically impossible) or indirect path (i.e. biologically possible). Here, PET was used to investigate whether a ...

journal_title：Neuroreport

authors： Stevens JA,Fonlupt P,Shiffrar M,Decety J

更新日期：2000-01-17 00:00:00