Possible involvement of neuropeptidergic sensory nerves in alopecia areata.

abstract：:Stop-consonant discrimination was investigated in normal-hearing listeners and cochlear-implanted patients (CIP) by recording auditory evoked potentials (AEPs) to /b epsilon/ and /p epsilon/ syllables. This study demonstrates that: (i) AEPs show time-locked components that mimic the temporal structure of the stimuli, ...

journal_title：Neuroreport

authors： Roman S,Canévet G,Lorenzi C,Triglia JM,Liégeois-Chauvel C

更新日期：2004-03-22 00:00:00

abstract：:Amyotrophic lateral sclerosis is a devastating motor neuron disorder. Traditionally regarded as a 'neuron only' disease, recent evidence suggested that other cells contribute critically to the pathogenesis. This review provides a short synopsis of the role neuroinflammation and microglial cells play in the disease and...

journal_title：Neuroreport

authors： Weydt P,Möller T

更新日期：2005-04-25 00:00:00

abstract：:Acute injury to central nervous system (CNS) triggers neurodegenerative processes that can result in serious damage or complete loss of function. After injury, production of transforming growth factor β1 (TGFβ1) increases and initiates creation of a fibrotic scar that prevents normal growth, plasticity, and recovery o...

journal_title：Neuroreport

authors： Jaskova K,Pavlovicova M,Cagalinec M,Lacinova L,Jurkovicova D

更新日期：2014-03-26 00:00:00

abstract：:Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...

journal_title：Neuroreport

authors： Cho BR,Yoon HS,Kim WY,Vezina P,Kim JH

更新日期：2017-08-02 00:00:00

abstract：:We examined the biology of AMPA/kainate-induced motor neuron degeneration using dissociated spinal cord cultures and motor neuron-specific antibodies which enable characterization of individual motor neurons in culture. Cobalt, which is thought to pass through Ca2+-permeable AMPA/kainate receptors following kainate ex...

journal_title：Neuroreport

authors： Bar-Peled O,O'Brien RJ,Morrison JH,Rothstein JD

更新日期：1999-03-17 00:00:00

abstract：:To test the hypothesis that the pedunclopontine tegmental nucleus (PPTg) plays a role in anxiety, rats with electrolytic lesions of the PPTg were tested in two animal models of anxiety, the elevated plus maze and the social interaction tests. Histological analysis showed that lesions were concentrated on the caudal ha...

journal_title：Neuroreport

authors： Podhorna J,Franklin KB

更新日期：1998-06-01 00:00:00

abstract：:Functional homology between human and macaque visual cortices has provided an important cue to functional subdivisions of the human visual cortex, but it is unclear beyond V1. We estimated the sizes and the visual field eccentricity functions of the extrastriate visual areas of human brains using MRI and fMRI measurem...

journal_title：Neuroreport

authors： Ejima Y,Takahashi S,Yamamoto H,Fukunaga M,Tanaka C,Ebisu T,Umeda M

更新日期：2003-08-26 00:00:00

abstract：:To examine the relationship between plasma lipoproteins and apolipoproteins in men with convictions for violent offences, blood was obtained from 15 men with a history of violence who were serving prison sentences for violent offences, and 25 age-matched male controls from the staff of the Argyll and Bute Psychiatric ...

journal_title：Neuroreport

authors： Gray RF,Corrigan FM,Strathdee A,Skinner ER,van Rhijn AG,Horrobin DF

更新日期：1993-06-01 00:00:00

abstract：:Music is an essential communication tool that can convey emotional information. Segmentation of a sound stream of music at event boundaries is necessary for identification and extraction of musical context and features. To investigate recognition of music termination structure, or cadence, we composed music sequences ...

journal_title：Neuroreport

authors： Hoshi-Shiba R,Furukawa K,Okanoya K

更新日期：2014-07-09 00:00:00

abstract：:This study was designed to investigate the expression of transient receptor potential melastatin 3 (TRPM3) and transient receptor potential vanilloid type 4 (TRPV4) in the trigeminal spinal subnucleus caudalis of a rat model of trigeminal neuralgia (TN). The influence of botulinum toxin type A (BTX-A) on the expressio...

journal_title：Neuroreport

authors： Zhang Y,Su Q,Lian Y,Chen Y

更新日期：2019-07-03 00:00:00

abstract：:Both ice-like protease and calpain have been shown to be involved in apoptosis in non-neuronal cells. Cultured rat cerebellar granule neurons undergo apoptosis when exposed to low potassium-containing medium. Calpain inhibitors 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid (PD150606) and N-acetyl-Leu-Leu-Met-CHO (c...

journal_title：Neuroreport

authors： Nath R,Raser KJ,McGinnis K,Nadimpalli R,Stafford D,Wang KK

更新日期：1996-12-20 00:00:00

abstract：:A fundamental issue in neuronal and glial cells is how intracellular rises in Ca2+ are coupled to signaling cascades and changes in subcellular morphology. We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS. Here, we demonstrate the pr...

journal_title：Neuroreport

authors： Clemen CS,Herr C,Lie AA,Noegel AA,Schröder R

更新日期：2001-05-08 00:00:00

abstract：:Nerve growth factor (NGF) is trophic to sensory and sympathetic fibres, and ciliary neurotrophic factor (CNTF) to motoneurones, in animal models of peripheral nerve injury: NGF excess produces hyperalgesia. In this first study of injured human nerves and sensory ganglia, we quantified and localized endogenous NGF and ...

journal_title：Neuroreport

authors： Anand P,Terenghi G,Birch R,Wellmer A,Cedarbaum JM,Lindsay RM,Williams-Chestnut RE,Sinicropi DV

更新日期：1997-05-27 00:00:00

abstract：:Oculopharyngeal muscular dystrophy (OPMD) is an autosomal dominant muscular dystrophy characterized by late onset ptosis, proximal muscle weakness and swallowing difficulties. This disease has been recently linked to chromosome 14q11.2-q13 in French-Canadian pedigrees. We studied three unrelated American families with...

journal_title：Neuroreport

authors： Grewal RP,Cantor R,Turner G,Grewal RK,Detera-Wadleigh SD

更新日期：1998-04-20 00:00:00

abstract：:Voltage-gated sodium channels consist of a pore-containing alpha-subunit and one or more auxiliary beta-subunits, which may modulate channel function. We previously demonstrated that sodium channel SNS/PN3 alpha-subunits were decreased in human sensory cell bodies after spinal root avulsion injury, and accumulated at ...

journal_title：Neuroreport

authors： Coward K,Jowett A,Plumpton C,Powell A,Birch R,Tate S,Bountra C,Anand P

更新日期：2001-03-05 00:00:00

abstract：:Unilateral neglect has been recently shown to be improved following a short period of adaptation to wedge prisms. The present study investigates whether visuo-motor adaptation can generate a bias in normals on line bisection tasks classically used to assess unilateral neglect. Our results show that adaptation to left-...

journal_title：Neuroreport

authors： Colent C,Pisella L,Bernieri C,Rode G,Rossetti Y

更新日期：2000-06-26 00:00:00

abstract：:Using functional magnetic resonance imaging (fMRI), we investigated whether the response of auditory and visual cortex was modulated by attending selectively to either heard or seen numbers presented simultaneously. Alternating attention between modalities modulated fMRI signal within the corresponding sensory cortex....

journal_title：Neuroreport

authors： Woodruff PW,Benson RR,Bandettini PA,Kwong KK,Howard RJ,Talavage T,Belliveau J,Rosen BR

更新日期：1996-08-12 00:00:00

abstract：:Adenosine has an anticonvulsant effect in various models of epilepsy. This effect appears to be mediated through the activation of adenosine A1 receptors (A1Rs). We immunohistochemically investigated the changes of A1Rs expression in kainate-treated and hippocampus-kindled rats as chronic models of epilepsy. In the no...

journal_title：Neuroreport

authors： Ochiishi T,Takita M,Ikemoto M,Nakata H,Suzuki SS

更新日期：1999-11-26 00:00:00

abstract：:The aim of this study was to show that Cl(-)-dependent excitotoxicity, with its characteristic cell swelling, involves actual water influx into the intracellular compartment. Taking advantage of the Ca2+ omission paradigm of Cl(-)-dependent excitotoxicity, in the chick embryonic neural retina ex vivo, which is associa...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramirez G

更新日期：2000-11-27 00:00:00

abstract：:Unilateral 6-hydroxydopamine lesion to rat substantia nigra pars compacta resulted in a modest, but significant, decrease in the specific binding of N-alpha-[methyl-3H]histamine (19 +/- 5% reduction) to synaptosomal membranes from ipsilateral striata. Dopamine synthesis was assessed in striatal slices by determining [...

journal_title：Neuroreport

authors： Molina-Hernández A,Nuñez A,Arias-Montaño JA

更新日期：2000-01-17 00:00:00

abstract：:The potent and selective AMPA receptor antagonist NBQX was tested for cytoprotective properties in an adult rat model of transient focal neocortical ischemia. Nineteen spontaneously hypertensive rats sustained 2 h of middle cerebral artery occlusion, followed by 22 h of recirculation. Ninety minutes following the onse...

journal_title：Neuroreport

authors： Buchan AM,Xue D,Huang ZG,Smith KH,Lesiuk H

更新日期：1991-08-01 00:00:00

abstract：:Injury and diseases of the nervous system can induce astrocytes to form tenacious glial scars. We induced focal cortical freeze-lesions in neonatal rats and examined scars histologically and electrophysiologically in tissue slices isolated 2-3 weeks after lesioning. Lesions displayed marked gliosis, characterized by u...

journal_title：Neuroreport

authors： Bordey A,Hablitz JJ,Sontheimer H

更新日期：2000-09-28 00:00:00

abstract：:Previous studies have suggested that the dorsomedial prefrontal cortex (dmPFC) plays a central role in processing first impressions; however, little is known about how dmPFC processes different valences of first impressions. Moreover, it is still unclear as to whether the dmPFC shows lateralization or only induces dif...

journal_title：Neuroreport

authors： Yu CL,Wang MY,Hu JF

更新日期：2016-05-25 00:00:00

abstract：:In this study we have used the transgenic mouse model Tg2576 to analyze the involvement of anomalous loss of regulation of cdk5 and the stress kinases JNK and p38 in brain neuronal death as related to neurodegenerative disorders such as Alzheimer's disease. Previous studies on hippocampal cells led us to the discovery...

journal_title：Neuroreport

authors： Otth C,Mendoza-Naranjo A,Mujica L,Zambrano A,Concha II,Maccioni RB

更新日期：2003-12-19 00:00:00

abstract：:Differences related to development were investigated using a finger isometric force task in children with cerebral palsy and control children. The increase in force and force control observed in controls did not take place in patients. In the younger subset of patients (< 10 years) the force produced by the non-affect...

journal_title：Neuroreport

authors： Smits-Engelsman BC,Rameckers EA,Duysens J

更新日期：2004-08-26 00:00:00

abstract：:We investigated the cardiovascular effects of bilateral microinjection of antisense oligodeoxynucleotides (oligos) into the nucleus tractus solitarii (NTS) to neuronal nitric oxide synthase (nNOS) to suppress the expression of nNOS molecular biologically. In urethane-anesthetized, paralyzed Wistar-Kyoto rats, bilatera...

journal_title：Neuroreport

authors： Maeda M,Hirano H,Kudo H,Doi Y,Higashi K,Fujimoto S

更新日期：1999-06-23 00:00:00

abstract：:The distribution of the enzyme NADPH diaphorase in the region of the periaqueductal gray (PAG) was studied in the rat, rabbit, cat, monkey and human. In each species, the enzyme labelled a small band of neurones located below the level of the aqueduct and directly above the supraoculomotor gray in the middle of the an...

journal_title：Neuroreport

authors： Carrive P,Paxinos G

更新日期：1994-11-21 00:00:00

abstract：:Transient global amnesia (TGA), characterised by a profound anterograde amnesia, is a model of interest to study the acquisition of novel meanings independent of episodic functioning. Three patients were tested during a TGA attack, two in the early recovery phase and the third during the acute phase of TGA, with a sem...

journal_title：Neuroreport

authors： Guillery B,Desgranges B,Katis S,de la Sayette V,Viader F,Eustache F

更新日期：2001-12-04 00:00:00

abstract：:TECTA and DFNA5 are the mouse orthologues of the human deafness-associated genes TECTA and DFNA5. To determine how expression of these genes is regulated during development, relative mRNA abundance was examined in mice by non-radioactive RT-PCR. TECTA mRNA was detected on embryonic day 15 (E15), increased to its highe...

journal_title：Neuroreport

authors： Maeda Y,Fukushima K,Kasai N,Maeta M,Nishizaki K

更新日期：2001-10-29 00:00:00

abstract：:Epilepsy is a neurological disorder with recurrent unprovoked seizures as the main symptom. Of the coumarin derivatives in Angelica gigas, decursin, a major coumarin component, was reported to exhibit significant protective activity against glutamate-induced neurotoxicity when added to primary cultures of rat cortical...

journal_title：Neuroreport

authors： Lee JK,Jeong JW,Jang T,Lee GW,Han H,Kang JS,Kim IH

更新日期：2014-11-12 00:00:00