Isolation of human delta-catenin and its binding specificity with presenilin 1.

abstract：:PEC-60, a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor, has been isolated, characterized and molecularly cloned. It shows biological activity as a hormone in both the gastrointestinal tract and in the immune system. We now report immunohistochemical evidence ...

journal_title：Neuroreport

authors： Fuxe K,Tinner B,Metsis M,Staines W,Morassutti D,Agnati LF,Ostensson CG,Efendic S,Agerberth B,Goldstein M

更新日期：1994-09-08 00:00:00

abstract：:Pharmacological manipulation of brain dopamine concentration affects visuospatial working memory in humans and in animals, the latter effects localized to the prefrontal cortex. However, the effects of dopamine agonists on humans are poorly understood. We hypothesized that bromocriptine would have an effect on cogniti...

journal_title：Neuroreport

authors： Kimberg DY,D'Esposito M,Farah MJ

更新日期：1997-11-10 00:00:00

abstract：:The current study examined the hemodynamic response during the Go/NoGo task in children with/without attention deficit/hyperactivity disorder (ADHD). Using near-infrared spectroscopy, oxy-Hb and deoxy-Hb concentration changes in the frontal areas were compared during the conditions with/without inhibitory demand. Comp...

journal_title：Neuroreport

authors： Inoue Y,Sakihara K,Gunji A,Ozawa H,Kimiya S,Shinoda H,Kaga M,Inagaki M

更新日期：2012-01-25 00:00:00

abstract：:An exaggerated startle response caused by mutations of the alpha 1 subunit gene of the inhibitory glycine receptor (GLRA1) is the key symptom of human hyperekplexia or startle disease. The recessive mouse mutant spasmodic (spd) carries a missense mutation in the corresponding murine Glra1 gene which reduces the affini...

journal_title：Neuroreport

authors： Koch M,Kling C,Becker CM

更新日期：1996-02-29 00:00:00

abstract：:The evaluative processing of the valence of action feedback is reflected by an event-related brain potential component called feedback-related negativity (FRN) or reward positivity (RewP). Recent studies have shown that FRN/RewP is markedly reduced when the action-feedback interval is long (e.g. 6000 ms), indicating t...

journal_title：Neuroreport

authors： Kimura K,Kimura M

更新日期：2016-09-28 00:00:00

abstract：:Humans afflicted with mood disorders respond differently to antidepressant drug therapy. Different responses to psychoactive drugs are also observed in rats, and specific strains exhibit substantial differences in gene expression following synaptic activity. We examined the effects of fluoxetine on the induction of Fo...

journal_title：Neuroreport

authors： Horowitz JM,Hallas BH,Torres G

更新日期：2002-12-20 00:00:00

abstract：:Counter-stimulation reduces pain perception; however, the role of attention during this process is rarely discussed despite attention itself being a well known modulator of pain perception. This study investigated the effect of attentional modulation on pain perception during counter-stimulation using fMRI. Subjects r...

journal_title：Neuroreport

authors： Longe SE,Wise R,Bantick S,Lloyd D,Johansen-Berg H,McGlone F,Tracey I

更新日期：2001-07-03 00:00:00

abstract：:This study aimed to examine the spontaneous hemodynamic fluctuations and the dysfunctional brain regions in patients with generalized anxiety disorder (GAD) using resting-state functional MRI. Previous studies have demonstrated some neural networks that are different in this patient group compared with healthy control...

journal_title：Neuroreport

authors： Li C,Su S,Wu H,Zhu Y

更新日期：2018-03-21 00:00:00

abstract：:The developmental time-course of type I and type II benzodiazepine receptors in the chick optic lobe was determined using a triazolopyridazine, CL 218872. At embryonic day 13 most of the binding sites corresponded to type II (98.23%), while type I represented only a minor proportion (1.77%). During development there w...

journal_title：Neuroreport

authors： Gravielle MC,de Plazas SF

更新日期：1995-10-23 00:00:00

abstract：:Studies in zebra finches failed to demonstrate the involvement of the NIf, a higher-order song nucleus afferent to the HVc, in the production of learned song. The song of the Bengalese finch, a related species, has a higher level of temporal organization; multiple song phrases are organized into a song. We hypothesize...

journal_title：Neuroreport

authors： Hosino T,Okanoya K

更新日期：2000-07-14 00:00:00

abstract：:Hyperactivity of the hypothalamic-pituitary-adrenal axis and impairment of the central corticotropin-releasing factor system are factors in the pathogenesis of depression. Though several antagonists of the corticotropin-releasing factor 1 receptor were effective in the recognized behavioral tests for antidepressant ac...

journal_title：Neuroreport

authors： Wang XB,Zhang YQ,Xue RR,Yang ZZ,Zhang XF

更新日期：2020-01-08 00:00:00

abstract：:The effects of high frequency repetitive transcranial magnetic stimulation on sensory perception and the pain tolerance thresholds were investigated applying both motor cortex stimulation and medial frontal cortex stimulation in normal study participants. Both the sensory perception and pain tolerance thresholds were ...

journal_title：Neuroreport

authors： Yoo WK,Kim YH,Doh WS,Lee JH,Jung KI,Park DS,Park ES

更新日期：2006-02-06 00:00:00

abstract：:In situ hybridization has demonstrated mRNA for olfactory receptors (OR) in the axon terminals of olfactory receptor neurons. Neurons that express the same OR appear to send their axons to two stereotyped glomeruli in the olfactory bulb (OB). Based on these observations, we tested the feasibility of using RT-PCR to is...

journal_title：Neuroreport

authors： Singer MS,Hughes TE,Shepherd GM,Greer CA

更新日期：1998-11-16 00:00:00

abstract：:The aim of this study was to show that Cl(-)-dependent excitotoxicity, with its characteristic cell swelling, involves actual water influx into the intracellular compartment. Taking advantage of the Ca2+ omission paradigm of Cl(-)-dependent excitotoxicity, in the chick embryonic neural retina ex vivo, which is associa...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramirez G

更新日期：2000-11-27 00:00:00

abstract：:Motor imagery paradigms can be used to investigate motor preparation. We used positron emission tomography to compare regional cerebral blood flow (rCBF) in patients with Parkinson's disease and normal controls under three conditions: rest, motor imagery and motor execution. In controls, imagery activated bilateral do...

journal_title：Neuroreport

authors： Samuel M,Ceballos-Baumann AO,Boecker H,Brooks DJ

更新日期：2001-03-26 00:00:00

abstract：:We have studied the distribution of mGluR2/3 in the mouse superior colliculus (SC) with antibody immunocytochemistry and the effect of enucleation on this distribution. We also compared this labeling to that for calbindin D28K. Anti-mGluR2/3-immunoreactive (IR) cells formed distinctive laminar patterns within the lowe...

journal_title：Neuroreport

authors： Kim MA,Jeon CJ

更新日期：1999-04-26 00:00:00

abstract：:Previous literature shows that feature binding processes elicit fronto-hippocampal areas. The time course of this process, however, remains unknown. This is the first study that investigates feature binding using magnetoencephalography. Synthetic aperture magnetometry analysis was used to localize sources of increased...

journal_title：Neuroreport

authors： Filbey FM,Holroyd T,Carver F,Sunderland T,Cohen RM

更新日期：2005-11-07 00:00:00

abstract：:Subcortical lesions have been simultaneously implicated in both real and simulated movement deficits. However, the analysis of the simulated opposition axis in precision grasping reveals that, in individuals with idiopathic bilateral Parkinson' disease motor imagery is impaired and that execution of overt movements is...

journal_title：Neuroreport

authors： Frak V,Cohen H,Pourcher E

更新日期：2004-06-28 00:00:00

abstract：:To confirm neural plasticity of the mouse hippocampo-prefrontal cortex (PFC) pathway, paired-pulse facilitation (PPF) and long-term potentiation (LTP) induction were determined in the pathway. In addition, we tested whether the plasticity differs in projections of the pathway from the dorsal (upper) and ventral (lower...

journal_title：Neuroreport

authors： Izaki Y,Takita M,Nomura M

更新日期：2001-05-08 00:00:00

abstract：:Experimental and clinical studies have revealed that angiotensin II type 1 receptor blocker has protective effects against ischemic brain injury, but the mechanism is still obscure. Angiotensin II type 1 receptor blocker may also have effects on neurogenesis through the activation of unblocked angiotensin II type 2 re...

journal_title：Neuroreport

authors： Wakai T,Yoshioka H,Yagi T,Kato T,Kinouchi H

更新日期：2011-06-11 00:00:00

abstract：:A prominent theory of the N2 event-related potential component holds that the 'oddball' N2 is generated in the anterior cingulate cortex. However, observations of oddball N2s with posterior scalp distributions are inconsistent with this hypothesis. We suggest that variability in the topology of the oddball N2 is a key...

journal_title：Neuroreport

authors： Warren CM,Tanaka JW,Holroyd CB

更新日期：2011-12-07 00:00:00

abstract：:Several neurophysiological studies have highlighted the role of the midbrain periaqueductal gray matter (PAG) in the initiation of vocalization in various animal species, from frogs to primates. With regard to humans, only two cases of complete mutism following a lesion to the PAG have been reported so far. This artic...

journal_title：Neuroreport

authors： Esposito A,Demeurisse G,Alberti B,Fabbro F

更新日期：1999-03-17 00:00:00

abstract：:In this study, we ask whether or not the involuntary capture of attention by a specific information type can produce domain-specific activation. Participants indicated the presence of a flicker in rapidly alternating letter-string masks presented in the periphery. Despite letters not being relevant to the task, we fou...

journal_title：Neuroreport

authors： Finkbeiner M,Slotnick SD,Moo LR,Caramazza A

更新日期：2007-07-02 00:00:00

abstract：:The present study examined potential neuroprotective effects of HU-211, a synthetic non-psychotropic cannabinoid with non-competitive NMDA antagonist properties on neurones exposed to various excitotoxins in culture. HU-211 was found to protect neurones from NMDA and quisqualate-induced toxicity but not that produced ...

journal_title：Neuroreport

authors： Eshhar N,Striem S,Biegon A

更新日期：1993-12-13 00:00:00

abstract：:In marked contrast to several other species, including rats and humans, leptin gene expression is undetectable in mouse brain. This unexpected finding may reflect unique energy regulation pathways in the mouse. We investigated possible mechanisms by which leptin (ob) gene expression is suppressed in mouse brain: (a) t...

journal_title：Neuroreport

authors： Brown RE,Wilkinson DA,Wilkinson PM,Imran SA,Wilkinson M

更新日期：2012-10-24 00:00:00

abstract：:Increased oxidative stress in the brain due to chronic ethanol consumption is known to result in a number of neurodegenerative changes. This study was designed to test whether dietary supplementation of grape polyphenols (GP) can offer protection to the neurodegenerative changes resulting from chronic ethanol consumpt...

journal_title：Neuroreport

authors： Sun GY,Xia J,Draczynska-Lusiak B,Simonyi A,Sun AY

更新日期：1999-01-18 00:00:00

abstract：:The perifornical-lateral hypothalamic area is implicated in regulating waking and paradoxical sleep. The blockade of GABAA receptors by iontophoretic applications of bicuculline (or gabazine) into the perifornical-lateral hypothalamic area induced a continuous quiet waking state associated to a robust muscle tone in h...

journal_title：Neuroreport

authors： Goutagny R,Luppi PH,Salvert D,Gervasoni D,Fort P

更新日期：2005-07-13 00:00:00

abstract：:Event related potentials (ERP) were recorded from 29 electrode positions in 10 normal subjects while they performed a simplified version of the Wisconsin Card Sorting Test (WCST). The design focused on ERP differences between early and late trials within each WCST series. Topographic and dipole analyses confirmed the ...

journal_title：Neuroreport

authors： Barceló F,Rubia FJ

更新日期：1998-03-09 00:00:00

abstract：:Dysfunctional glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. Abnormal expressions in schizophrenia of ionotropic glutamate receptors (iGluRs) and the proteins that regulate their trafficking have been found to be region and subunit specific in brain, suggesting that abnormal t...

journal_title：Neuroreport

authors： Tucholski J,Simmons MS,Pinner AL,McMillan LD,Haroutunian V,Meador-Woodruff JH

更新日期：2013-08-21 00:00:00

abstract：:Neural plasticity in the visual cortex, as tested by changes in its functional organization induced by monocular deprivation (MD), is present only during a restricted period of postnatal development (critical period). To investigate whether this process of synapse strengthening depends upon NGF, we antagonized endogen...

journal_title：Neuroreport

authors： Domenici L,Cellerino A,Berardi N,Cattaneo A,Maffei L

更新日期：1994-10-27 00:00:00