Effect of hindlimb unloading on stereological parameters of the motor cortex and hippocampus in male rats.

abstract：:In the water-maze test, the linoleic acid derivative, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) (1 mg/kg, intraperitoneally), significantly shortened the prolonged latency for accelerated-senescence-prone mice 8 (SAMP8), reaching a level similar to the latency for accelerated-senescence-res...

journal_title：Neuroreport

authors： Yaguchi T,Nagata T,Mukasa T,Fujikawa H,Yamamoto H,Yamamoto S,Iso H,Tanaka A,Nishizaki T

更新日期：2006-01-23 00:00:00

abstract：:Single-pulse unilateral electrical stimulation of either the amygdala or the inferior colliculus elicited startle-like responses in chloral hydrate anesthetized rats. EMG responses to intracranial stimulation were recorded from the anterior biceps femoris muscles. The EMG responses were generally enhanced following un...

journal_title：Neuroreport

authors： Lin C,Wan X,Zhao W,Ma C,Ma C,Gao Y,Zhou Y,Yeomans JS,Li L

更新日期：2002-10-07 00:00:00

abstract：:We show that the pro-apoptotic proteins Bax and Bak trigger apoptosis when over-expressed in sympathetic neurons cultured in the presence of NGF. This effect can be blocked with z-VAD-fmk, a peptide inhibitor of caspases, but not with anti-apoptotic chemical compounds such as antioxidants or proteasome inhibitors. The...

journal_title：Neuroreport

authors： Martinou I,Missotten M,Fernandez PA,Sadoul R,Martinou JC

更新日期：1998-01-05 00:00:00

abstract：:Effects of glutamate on synaptic transmission in the submucosal plexus of guinea-pig small intestine were studied with intracellular electrophysiological recording methods. Glutamate suppressed stimulus-evoked slow excitatory postsynaptic potentials (EPSPs) and increased the amplitude of slow inhibitory postsynaptic p...

journal_title：Neuroreport

authors： Ren J,Hu HZ,Liu S,Xia Y,Wood JD

更新日期：1999-09-29 00:00:00

abstract：:The transmissible spongiform encephalopathies (TSEs) invariably result in fatal neurodegeneration and accumulation of PrP, an abnormal form of the host prion protein PrP, encoded by the PRNP gene. A naturally occurring polymorphism (methionine/valine) at PRNP codon 129 is associated with variation in relative disease ...

journal_title：Neuroreport

authors： O'Rourke KI,Spraker TR,Zhuang D,Greenlee JJ,Gidlewski TE,Hamir AN

更新日期：2007-12-03 00:00:00

abstract：:Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...

journal_title：Neuroreport

authors： McClure MM,Threlkeld SW,Rosen GD,Holly Fitch R

更新日期：2005-08-22 00:00:00

abstract：:With the purpose of mapping representations of the finger and proximal arm in the human primary motor cortex (MI), we measured regional cerebral blood flow (rCBF) in eight right-handed normal volunteers during self-paced finger and proximal arm movements. Each movement activated two different fields in MI, one located...

journal_title：Neuroreport

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Yanagisawa T

更新日期：1995-01-26 00:00:00

abstract：:Previous studies have established a role for N-methyl-D-aspartate receptor (NMDAR) containing the GluN2B subunit in efficient learning behavior on a variety of tasks. Recent findings have suggested that NMDAR on GABAergic interneurons may underlie the modulation of striatal function necessary to balance efficient acti...

journal_title：Neuroreport

authors： Brigman JL,Daut RA,Saksida L,Bussey TJ,Nakazawa K,Holmes A

更新日期：2015-06-17 00:00:00

abstract：:Event-related potentials were recorded in healthy volunteers to test the accuracy of the human brain to extract, preattentively, auditory abstract rules. The abstract rule was determined by the frequency relationship between two pure tones forming a pair. The standard pairs had identical tone frequency, whereas the de...

journal_title：Neuroreport

authors： Carral V,Corral MJ,Escera C

更新日期：2005-02-28 00:00:00

abstract：:Two monkeys were trained in a delayed sequential motor task in which the time interval between events and the delay duration were either fixed or variable. Single-unit neuronal activity was recorded in the pre-supplementary motor area (pre-SMA). During the delay, we observed a gradual increase in activity (build-up pa...

journal_title：Neuroreport

authors： Akkal D,Escola L,Bioulac B,Burbaud P

更新日期：2004-06-07 00:00:00

abstract：:Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...

journal_title：Neuroreport

authors： Benson PJ,Guo K,Hardiman MJ

更新日期：1999-11-26 00:00:00

abstract：:The function of the lateral part of the human cerebellum was investigated through cerebro-cerebellar functional connectivity. We propose a laterality index method to reveal a functional and possibly anatomical pathway between the cerebral cortex and the cerebellum. The brain activity involved in learning a visually-gu...

journal_title：Neuroreport

authors： Tamada T,Miyauchi S,Imamizu H,Yoshioka T,Kawato M

更新日期：1999-02-05 00:00:00

abstract：:SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identifie...

journal_title：Neuroreport

authors： Fang ZX,Hong SQ,Li TS,Wang J,Xie LL,Han W,Jiang L

更新日期：2019-06-12 00:00:00

abstract：:Various clinical populations display atypical volume asymmetry of language structures and also the auditory M100 source. Although such atypical volume asymmetries have also been observed in autism, M100 source asymmetries have not yet been investigated. We examined M100 asymmetry in autism and its relationship with la...

journal_title：Neuroreport

authors： Schmidt GL,Rey MM,Oram Cardy JE,Roberts TP

更新日期：2009-07-15 00:00:00

abstract：:The present study examined the effect of pre-exposure to a moderate dose of caffeine (20 mg kg-1) on the acquisition of self-administration of cocaine (0.125 mg kg-1/infusion or 0.25 mg kg-1/infusion) in the rat. Rats pre-exposed to caffeine acquired self-administration more rapidly. Furthermore, sensitization to coca...

journal_title：Neuroreport

authors： Horger BA,Wellman PJ,Morien A,Davies BT,Schenk S

更新日期：1991-01-01 00:00:00

abstract：:Apolipoprotein E (apoE) and the beta-amyloid peptide are both found in the senile plaques associated with Alzheimer's disease. Several studies have recently determined that apoE can prevent beta-amyloid fibril (Abetaf) formation in vitro. In vivo, apoE is normally associated with a lipid source. We show that both reco...

journal_title：Neuroreport

authors： Beffert U,Poirier J

更新日期：1998-10-05 00:00:00

abstract：:Oleic acid, a cis-unsaturated free fatty acid, is proposed to be involved in the protein kinase C (PKC) activation pathway. Its biological actions, however, have not been well-characterized. We examined the effects of oleic acid on acetylcholine (ACh)-gated channel currents using Torpedo nicotinic ACh receptors expres...

journal_title：Neuroreport

authors： Nishizaki T,Ikeuchi Y,Matsuoka T,Sumikawa K

更新日期：1997-02-10 00:00:00

abstract：:Amyotrophic lateral sclerosis is an incurable disease in which cerebral and spinal motoneurons degenerate, causing paralysis and death within 2-5 years. One of the pathogenic factors of motoneuron death is a chronic excess of glutamate, which exceeds its removal by astrocytes, i.e. excitotoxicity. Extra glutamate upta...

journal_title：Neuroreport

authors： Wisman LA,van Muiswinkel FL,de Graan PN,Hol EM,Bär PR

更新日期：2003-10-27 00:00:00

abstract：:Recently it has been reported that a missense G(88)C mutation within exon 3 and a missense G(209)A mutation within exon 4 of the alpha-synuclein gene were linked to familial Parkinson's Disease (PD). We decided to investigate if these and any other mutations in exons 3 and 4 of the alpha-synuclein gene could be detect...

journal_title：Neuroreport

authors： El-Agnaf OM,Curran MD,Wallace A,Middleton D,Murgatroyd C,Curtis A,Perry R,Jaros E

更新日期：1998-12-01 00:00:00

abstract：:It is well established that Parkinson's disease leads to impaired learning from reward and enhanced learning from punishment. The administration of dopaminergic medications reverses this learning pattern. However, few studies have investigated the neural underpinnings of these cognitive processes. In this study, using...

journal_title：Neuroreport

authors： Argyelan M,Herzallah M,Sako W,DeLucia I,Sarpal D,Vo A,Fitzpatrick T,Moustafa AA,Eidelberg D,Gluck M

更新日期：2018-05-02 00:00:00

abstract：:Neuroblastoma cell lines are useful for the investigation of neuronal receptor regulation since these cells display various neuronal features. Here we report the analysis of human AMPA and kainate receptor expression in four neuroblastoma cell lines (SK-N-MC, IMR-32, CHP 126 and NMB/N7). The reverse transcriptase-poly...

journal_title：Neuroreport

authors： Korczak B,McWhinnie EA,Fletcher EJ,Kamboj RK

更新日期：1995-04-19 00:00:00

abstract：:The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

journal_title：Neuroreport

authors： Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

更新日期：1996-04-10 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) exhibits neurotrophic properties on different types of neurones, including fetal motoneurones and embryonic neurones of sensory ganglia. We demonstrate that chronic injury to the adult rat sciatic nerve induces a rapid up-regulation of GDNF mRNA expression in Schwann ...

journal_title：Neuroreport

authors： Hammarberg H,Piehl F,Cullheim S,Fjell J,Hökfelt T,Fried K

更新日期：1996-03-22 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00

abstract：:The present study examined the neuroprotective effects of choroid plexus isolated from adult rats and encapsulated within alginate microcapsules. In vitro, conditioned media from cultured choroid plexus produced a marked, dose-dependent protection of embryonic cortical neurons against serum deprivation-induced cell de...

journal_title：Neuroreport

authors： Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

更新日期：2004-07-19 00:00:00

abstract：:We measured regional cerebral blood flow using positron emission tomography in seven normal volunteers during discrimination tasks for visual patterns. For the 'attention to right or left' tasks, the subjects were instructed to press a key when sample and test stimuli presented in the right or left visual fields, resp...

journal_title：Neuroreport

authors： Kawashima R,Satoh K,Goto R,Inoue K,Itoh M,Fukuda H

更新日期：1998-05-11 00:00:00

abstract：:We investigated the effect of the muscarinic acetylcholine receptor (mAChR) antagonist scopolamine on eyeblink conditioning in glutamate receptor subunit 62 null mice, which have severe impairments in cerebellar long-term depression (LTD). Mice were injected intraperitoneally with scopolamine (0.5 mg/kg) or saline, an...

journal_title：Neuroreport

authors： Takatsuki K,Kawahara S,Mori H,Mishina M,Kirino Y

更新日期：2002-01-21 00:00:00

abstract：:After learning position discrimination in a T-maze water escape task, rats had either a 2 mm section of the middle cerebral artery removed bilaterally (bMCA) or they received a sham operation. Beginning on the day of surgery either total brain gangliosides (50 mg kg-1) or saline were administered daily for five days. ...

journal_title：Neuroreport

authors： McDaniel WF,Fjordbak T,Schmidt MS,Tucker JC,Davis BK

更新日期：1991-11-01 00:00:00

abstract：:In an earlier screening, we identified several genes for kinases that might control the extension of neurites. One of these genes encoded a leukocyte tyrosine kinase (LTK), which is a receptor tyrosine kinase whose ligands remain to be identified. To examine the possible role of this LTK in neurite outgrowth, we const...

journal_title：Neuroreport

authors： Yamada S,Nomura T,Takano K,Fujita S,Miyake M,Miyake J

更新日期：2008-11-19 00:00:00

abstract：:Learning and memory are cognitive functions commonly impaired after surgery, especially in elderly patients. Our aim was to evaluate the effect of sevoflurane anaesthesia on episodic-like memory in young and aged wild-type mice and mice with altered nicotinic cholinergic neurotransmission (beta2KO). Mice learned objec...

journal_title：Neuroreport

authors： Wiklund A,Granon S,Faure P,Sundman E,Changeux JP,Eriksson LI

更新日期：2009-10-28 00:00:00