Neurophysiological evidence for the country-of-origin effect: an event-related potential study.

abstract：:Canine degenerative myelopathy (DM) is a fatal neurodegenerative disorder prevalent in the canine population. It may represent a unique, naturally occurring disease model for human amyotrophic lateral sclerosis (ALS) because of similar clinical signs and association with superoxide dismutase 1 gene (SOD1) mutations. M...

journal_title：Neuroreport

authors： Chang RC,Parakh S,Coates JR,Long S,Atkin JD

更新日期：2019-01-02 00:00:00

abstract：:EphA5 and its ligand ephrin-A5 interaction can trigger synaptogenesis during early hippocampus development. We have previously reported that abnormal EphA5 expression can result in synaptogenesis disorder in congenital hypothyroidism (CH) rats. To better understand its precise molecular mechanism, we further analyzed ...

journal_title：Neuroreport

authors： Suo G,Shen F,Sun B,Song H,Xu M,Wu Y

更新日期：2018-08-01 00:00:00

abstract：:It has been widely shown that recognition memory includes two distinct retrieval processes: familiarity and recollection. Many studies have shown that recognition memory can be facilitated when there is a perceptual match between the studied and the tested items. Most event-related potential studies have explored the ...

journal_title：Neuroreport

authors： Cui X,Gao C,Zhou J,Guo C

更新日期：2016-09-28 00:00:00

abstract：:Inherited retinal degenerations such as retinitis pigmentosa (RP) are characterized by progressive loss of photoreceptors, apparently by apoptosis, and our recent report of increased secreted Frizzled-related protein-2 (SFRP2) in RP retinas suggests altered Wnt signalling may be a component of the degenerative process...

journal_title：Neuroreport

authors： Jones SE,Jomary C,Grist J,Stewart HJ,Neal MJ

更新日期：2000-12-18 00:00:00

abstract：:Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, how...

journal_title：Neuroreport

authors： Francl JM,Kaur G,Glass JD

更新日期：2010-11-17 00:00:00

abstract：:The neurotrophin-inducible gene VGF plays an important role in the maintenance of organismal energy balance and in the mediation of hippocampal synaptic activity. The regulatory mechanism of VGF transcription is not fully understood. The neuron-restrictive silencer factor (NRSF) binds with the neuron-restrictive silen...

journal_title：Neuroreport

authors： Moon SM,Kim JS,Park BR,Kim DK,Kim SG,Kim HJ,Chun HS,Lee BK,Kim CS

更新日期：2015-02-11 00:00:00

abstract：:Three SNARE proteins, SNAP-25, syntaxin 1A, and VAMP2 or synaptobrevin 2, constitute the minimal functional machinery needed for the regulated secretion of neurotransmitters. Dynamic changes in the regulated release of neurotransmitters are associated with the induction of long-term plasticity at central synapses. In-...

journal_title：Neuroreport

authors： Irfan M,Zurawski Z,Hamm HE,Bark C,Stanton PK

更新日期：2019-07-03 00:00:00

abstract：:This study aimed to explore the temporal dynamics of the consistency effect in reading Chinese phonograms. High-consistency and low-consistency characters were used in the homophone judgment task, and the event-related potentials were recorded. The data showed that low-consistency characters elicited greater N170 ampl...

journal_title：Neuroreport

authors： Lee CY,Tsai JL,Chan WH,Hsu CH,Hung DL,Tzeng OJ

更新日期：2007-01-22 00:00:00

abstract：:Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, and humoral immunity is suggested to play an important role in the pathogenesis. The identification of an anti-aquaporin-4 antibody (AQP4-Ab, neuromyelitis optica immunoglobulin G) in the sera of patients with NMO has le...

journal_title：Neuroreport

authors： Kinoshita M,Nakatsuji Y,Moriya M,Okuno T,Kumanogoh A,Nakano M,Takahashi T,Fujihara K,Tanaka K,Sakoda S

更新日期：2009-03-25 00:00:00

abstract：:Abnormal sleep architecture and white matter hyperintensities (WMHs) may be involved in cognitive impairment. There is little evidence on the connections between WMHs and chronic insomnia disorder (CID). Therefore, we evaluated the severity of WMHs and polysomnography parameters as well as cognitive tests to explore t...

journal_title：Neuroreport

authors： Lu S,Song L,Wang D,Zhang X,Lv X,Yin H,Gao Y,Liu X,Tang J

更新日期：2019-06-12 00:00:00

abstract：:When two cylinders are passively moved in-phase on the volar surface of the right second and third fingers, human subjects estimate the stimuli to originate from one object, whereas two separate objects are estimated for out-of-phase stimuli. While five blindfolded subjects performed this estimation task, brain activi...

journal_title：Neuroreport

authors： Kitada R,Kochiyama T,Hashimoto T,Naito E,Matsumura M

更新日期：2003-04-15 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00

abstract：:The serum-free mouse embryo (SFME) cell line, derived from 16-day-old mouse embryos in medium in which serum was replaced by growth factors and other supplements, has been cultured for more than 200 generations. SFME cells are nontumorigenic, lack gross chromosomal abnormalities, and display characteristics of CNS pro...

journal_title：Neuroreport

authors： Loo DT,Althoen MC,Cotman CW

更新日期：1994-08-15 00:00:00

abstract：:We investigated the mode of action of argiotoxin636 on isolated N-methyl-D-aspartate (NMDA) receptor channels in cultured cerebellar granule cells. We found that the toxin blocks NMDA channels by decreasing their opening probability and by inducing a flickering activity, in a voltage-dependent manner. Our results indi...

journal_title：Neuroreport

authors： Fagni L,Bockaert J

更新日期：1995-05-09 00:00:00

abstract：:In the present study, changes in the cytokine system (IL-1 beta, IL-2, IL-3, IL-6 and TNF alpha) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNF alpha, a decrease in that of IL-2 and of IL-3 with no change in IL-1 beta and in IL-6 secretion lev...

journal_title：Neuroreport

authors： Mittwoch-Jaffe T,Shalit F,Srendi B,Yehuda S

更新日期：1995-03-27 00:00:00

abstract：:Nogo-A, a member of the reticulon family, is one of the most important myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the central nervous system. RhoA has been targeted pharmacologically to promote neurite outgrowth and functional recovery in the brain and spinal cord. However, the und...

journal_title：Neuroreport

authors： Wang H,Shen J,Xiong N,Zhao H,Chen Y

更新日期：2011-10-26 00:00:00

abstract：:Pharmacological manipulation of brain dopamine concentration affects visuospatial working memory in humans and in animals, the latter effects localized to the prefrontal cortex. However, the effects of dopamine agonists on humans are poorly understood. We hypothesized that bromocriptine would have an effect on cogniti...

journal_title：Neuroreport

authors： Kimberg DY,D'Esposito M,Farah MJ

更新日期：1997-11-10 00:00:00

abstract：:Chronic ethanol (EtOH) exposure can cause intracellular Ca overload by stimulating calcium channel receptors and trigger apoptosis of neurons. NCX3 may play a cytoprotective role in intracellular Ca excretion. In this study, the effect of EtOH on NCX3 was analyzed by observing NCX3 expression in the hippocampus of chr...

journal_title：Neuroreport

authors： Wang C,Wang X,Li Y,Xia Z,Liu Y,Yu H,Xu G,Wu X,Zhao R,Zhang G

更新日期：2019-04-10 00:00:00

abstract：:Neurotrophins are promising candidates to slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease in which spinal and cortical motoneurons selectively degenerate. In a long-term in vitro model, malonate-induced toxicity and cell death of motoneurons have been demonstrated. Here we stud...

journal_title：Neuroreport

authors： Van Westerlaak MG,Bär PR,Cools AR,Joosten EA

更新日期：2001-05-25 00:00:00

abstract：:Evidence of glutamatergic dysfunction in schizophrenia associated with the N-methyl-D-aspartate receptor has historically demonstrated changes primarily attributable to neurons. We propose an astrocytic component to N-methyl-D-aspartate receptor dysfunction in this illness. We studied the expression of serine racemase...

journal_title：Neuroreport

authors： Steffek AE,Haroutunian V,Meador-Woodruff JH

更新日期：2006-07-31 00:00:00

abstract：:Melatonin, a hormone from the pineal gland, was tested for its anticonvulsant effects in male gerbils. Daily administration of melatonin (25 micrograms injection-1, s.c.) for ten weeks reduced the number and severity of seizures (total convulsion score: 7.67 +/- 1.83 in controls vs 2.47 +/- 0.90 in melatonin-injected ...

journal_title：Neuroreport

authors： Champney TH,Champney JA

更新日期：1992-12-01 00:00:00

abstract：:The localization of the melanocortin 1 (MC1) receptor in brain was investigated by in situ hybridization and immunohistochemistry. In rat periaqueductal gray matter (PAG), a small number of cells which displayed a punctate distribution showed a specific hybridization signal for MC1 receptor mRNA, whereas other regions...

journal_title：Neuroreport

authors： Xia Y,Wikberg JE,Chhajlani V

更新日期：1995-11-13 00:00:00

abstract：:Deficits in auditory sensory memory at the electrophysiological level as indexed by mismatch negativity and those in auditory verbal memory at the neuropsychological level have been independently demonstrated in previous studies of schizophrenia. We predicted a specific association between these indices in schizophren...

journal_title：Neuroreport

authors： Kawakubo Y,Kasai K,Kudo N,Rogers MA,Nakagome K,Itoh K,Kato N

更新日期：2006-07-17 00:00:00

abstract：:We inserted microelectrodes in eye movement-evoking cortices (EMECs) of cats and examined whether neurones in the EMECs received sensory input from guide signals and fired prior to saccades. The five EMECs were the medial wall of the hemisphere under the cruciate sulcus, the medical and lateral bank of the presylvian ...

journal_title：Neuroreport

authors： Tamai Y,Kimura A

更新日期：1996-10-02 00:00:00

abstract：:To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

journal_title：Neuroreport

authors： Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

更新日期：2013-09-11 00:00:00

abstract：:Although most neurones in the PMLS of the cat are selective for direction of motion, whether the preferred directions are organized into cortical columns, as they are in the MT area of the monkey, is not certain. We have quantitatively investigated the organization of direction selectivity of PMLS neurones. The result...

journal_title：Neuroreport

authors： Wang Y,Wang L,Li B,Wang LH,Diao YC

更新日期：1995-10-23 00:00:00

abstract：:Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's disease. However, the role of SIRT2 in oxidative stress-induced cell death has remained unclear. In this study, we investigated the roles of SIRT2 in...

journal_title：Neuroreport

authors： Nie H,Hong Y,Lu X,Zhang J,Chen H,Li Y,Ma Y,Ying W

更新日期：2014-08-06 00:00:00

abstract：:Heptylene-linked bis-(9-amino-1,2,3,4-tetrahydroacridine) (bis(7)-tacrine) is a potential palliative therapeutic agent for Alzheimer's disease (AD), on the basis of its superior acetylcholinesterase (AChE) inhibition and memory-enhancing potency relative to tacrine. In this study we report that bis(7)-tacrine exhibits...

journal_title：Neuroreport

authors： Li CY,Wang H,Xue H,Carlier PR,Hui KM,Pang YP,Li ZW,Han YF

更新日期：1999-03-17 00:00:00

abstract：:Our aim was to visualize the dynamic features of Ca2+/calmodulin-dependent protein kinase II (CaMKII) activity. In order to do so, we synthesized a new reagent by conjugating a fluoroprobe, 6-acryloyl-2-dimethylaminonaphthalene (acrylodan), to syntide 2, a specific peptide substrate for CaMKII. In cell-free conditions...

journal_title：Neuroreport

authors： Higashi H,Sato K,Omori A,Sekiguchi M,Ohtake A,Kudo Y

更新日期：1996-11-04 00:00:00

abstract：:In a previous publication we showed that non-linear analysis can extract spatio-temporal changes of brain electrical activity prior to epileptic seizures. Here we describe a new method to analyze this long-term non-stationarity in the EEG by a measure of dynamical similarity between different parts of the time series....

journal_title：Neuroreport

authors： Le Van Quyen M,Martinerie J,Baulac M,Varela F

更新日期：1999-07-13 00:00:00