Human amygdala activation detected with echo-planar functional magnetic resonance imaging.

Abstract:

:Echo-Planar functional magnetic resonance imaging (EP-fMRI) was used to study the activity of the amygdala while three normal female subjects viewed alternating blocks of affectively neutral and affectively negative still pictures. Bilateral activation in the amygdala that was significantly correlated with the changing valence of the visual stimuli was found in all three subjects. These findings are consistent with the large corpus of data from non-human studies suggesting that the amygdala is a key structure for extracting the affective significance from external stimuli. This is the first known report of phasic amygdala activation detected with EP-fMRI in normal human subjects responding to affective stimuli.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Irwin W,Davidson RJ,Lowe MJ,Mock BJ,Sorenson JA,Turski PA

doi

10.1097/00001756-199607290-00014

subject

Has Abstract

pub_date

1996-07-29 00:00:00

pages

1765-9

issue

11

eissn

0959-4965

issn

1473-558X

pii

00001756-199607290-00014

journal_volume

7

pub_type

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