IL-1 beta, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areas.

abstract：:Absence seizures are known to originate from disruptions within the corticothalamocortical network; however, the precise underlying cellular and molecular mechanisms that induce hypersynchronicity and hyperexcitability are debated and likely to be complex and multifactorial. Recent studies implicate impaired thalamic ...

journal_title：Neuroreport

authors： Seo S,Leitch B

更新日期：2017-12-13 00:00:00

abstract：:It has been reported that intracerebroventricular (i.c.v.) injection of nociception/orphanin FQ (OFQ) can antagonize morphine analgesia, whereas i.c.v. OFQ antibody can reverse morphine tolerance. Nocistatin (NST) is a recently characterized neuropeptide possessing an antagonizing effect on OFQ. Here we examine whethe...

journal_title：Neuroreport

authors： Sun RQ,Zhao CS,Wang HJ,Jing Z,Wang W,Yang K,Wang Y,Chang JK,Han JS

更新日期：2001-06-13 00:00:00

abstract：:The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

journal_title：Neuroreport

authors： Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

更新日期：2001-12-21 00:00:00

abstract：:Voltage-gated ionic current and the response to quinine were studied on the four types of morphologically identified taste cells of the bullfrog fungiform papilla by whole-cell patch clamp recording with a Lucifer yellow-filled pipette. Dye-coupled type Ia cells (mucous cells) did not show voltage-activated currents. ...

journal_title：Neuroreport

authors： Takeuchi H,Tsunenari T,Kurahashi T,Kaneko A

更新日期：2001-09-17 00:00:00

abstract：:Astrogliosis is an important component of the response to injury of the central nervous system (CNS). The Id family of helix-loop-helix (HLH) transcription factors has been implicated in the regulation of cellular differentiation in several different lineages and may contribute to the regulation of astrogliosis. We ex...

journal_title：Neuroreport

authors： Andres-Barquin PJ,Hernandez MC,Israel MA

更新日期：1998-12-21 00:00:00

abstract：:Cholinergic basal forebrain neurons (CBFN) expressing the low-affinity neurotrophin receptor p75 (p75(NTR)) were previously selectively labeled in vivo with carbocyanine 3 (Cy3)-tagged anti-p75(NTR), but the applied 192IgG-conjugates recognized p75(NTR) only in rat. The antibody ME 20.4 raised against human p75(NTR) h...

journal_title：Neuroreport

authors： Härtig W,Varga C,Kacza J,Grosche J,Seeger J,Luiten PG,Brauer K,Harkany T

更新日期：2002-08-07 00:00:00

abstract：:Event related potentials (ERP) were recorded from 29 electrode positions in 10 normal subjects while they performed a simplified version of the Wisconsin Card Sorting Test (WCST). The design focused on ERP differences between early and late trials within each WCST series. Topographic and dipole analyses confirmed the ...

journal_title：Neuroreport

authors： Barceló F,Rubia FJ

更新日期：1998-03-09 00:00:00

abstract：:Although prenatal stress has been repeatedly shown to inhibit adult neurogenesis in the dentate gyrus of offspring, its effects on embryonic and early postnatal brain development are not well described. Here, using the cell proliferation marker 5-bromo-2'-deoxyuridine, we examine for the first time the effect of prena...

journal_title：Neuroreport

authors： Kawamura T,Chen J,Takahashi T,Ichitani Y,Nakahara D

更新日期：2006-10-02 00:00:00

abstract：:We used positron emission tomography to investigate whether tactile motion discrimination activates the dorsal visual stream in congenitally blind (CB) participants compared with sighted controls. The tactile stimuli consisted of either static dots, dots moving coherently in one of two possible directions, or in rando...

journal_title：Neuroreport

authors： Ptito M,Matteau I,Gjedde A,Kupers R

更新日期：2009-04-22 00:00:00

abstract：:The ability to attribute mental states to others ('theory of mind') pervades normal social interaction and is impaired in autistic individuals. In a previous positron emission tomography scan study of normal volunteers, performing a 'theory of mind' task was associated with activity in left medial prefrontal cortex. W...

journal_title：Neuroreport

authors： Happé F,Ehlers S,Fletcher P,Frith U,Johansson M,Gillberg C,Dolan R,Frackowiak R,Frith C

更新日期：1996-12-20 00:00:00

abstract：:We evaluated the effects of chemical lesions on hindpaw inflammation-induced Fos protein expression in spinoparabrachial neurons that were retrogradely labeled by Fluoro-Gold. The descending serotoninergic and noradrenergic pathways were destroyed by the selective neurotoxins, 5,7-DHT and DSP-4, respectively. After 5,...

journal_title：Neuroreport

authors： Wei F,Dubner R,Ren K

更新日期：1999-06-03 00:00:00

abstract：:This study examined the relationship between social anxiety and the neural processing of threat in faces. Twenty-one adults with different levels of society anxiety were tested for their event-related potential responses to unattended threatening and nonthreatening faces, presented upright and upside-down, at three po...

journal_title：Neuroreport

authors： Sewell C,Palermo R,Atkinson C,McArthur G

更新日期：2008-08-27 00:00:00

abstract：:The apolipoprotein E (apoE) gene has been identified as a susceptibility gene for Alzheimer's disease, although the mechanism whereby apoE exerts this effect has not been determined. The aim of this study was to examine the intracellular fate of apoE and we demonstrate that in mammalian cells-transiently expressing ta...

journal_title：Neuroreport

authors： Lovestone S,Anderton BH,Hartley C,Jensen TG,Jorgensen AL

更新日期：1996-04-10 00:00:00

abstract：:Neurons respond to extracellular stimulation by modulating the expression of certain immediate-early genes. Inducible transcription factors (ITFs), such as c-Fos and Zif268, are coded by this class of gene and are among the first proteins to appear. The rapid accumulation of these products combined with histological m...

journal_title：Neuroreport

authors： Chaudhuri A

更新日期：1997-09-08 00:00:00

abstract：:There is disagreement in the literature as to whether smooth pursuit latency is reduced when a temporal gap is introduced between the extinction of a central fixation target and the illumination of an eccentric moving target. This study confirms that in human subjects smooth pursuit latency is reduced by gaps and that...

journal_title：Neuroreport

authors： Knox PC

更新日期：1998-03-30 00:00:00

abstract：:This study was carried out based on the assumption that brain-derived neurotrophic factor (BDNF) may counterbalance the action of morphine in the brain. Morphine analgesic tolerance after daily administrations for six days was blocked by intracerebroventricular injection of anti-BDNF IgG on day 5, but not by administr...

journal_title：Neuroreport

authors： Matsushita Y,Ueda H

更新日期：2009-01-07 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP-22) gene which results in abnormal myelination of the peripheral nervous system. However, the clinical symptoms observed in the mutant suggest abnormalities in the central nervous system. Using the Northern blot te...

journal_title：Neuroreport

authors： Bascles L,Bonnet J,Garbay B

更新日期：1994-06-02 00:00:00

abstract：:In this study, we determined whether the visuospatial attention network of frontal, parietal, and occipital cortex can be parsed into two different subsets of active regions associated with transient and sustained processes within the same cue-to-target delay period of an endogenously cued visuospatial attention task....

journal_title：Neuroreport

authors： Luks TL,Sun FT,Dale CL,Miller WL,Simpson GV

更新日期：2008-01-22 00:00:00

abstract：:Anterior cingulate integrity may be required for antidepressant response. To assess anterior cingulate processes related to treatment response, we studied error-related negativity and error positivity produced during an emotional go/no-go challenge, a task activating the rostral anterior cingulate. Twelve elderly pati...

journal_title：Neuroreport

authors： Alexopoulos GS,Murphy CF,Gunning-Dixon FM,Kalayam B,Katz R,Kanellopoulos D,Etwaroo GR,Klimstra S,Foxe JJ

更新日期：2007-02-12 00:00:00

abstract：:It has been suggested that lower motor neurons containing calcium-binding proteins (CBP) may be resistant to degeneration in motor neuron disease. The testing of this hypothesis is hampered by lack of comprehensive information regarding the presence of CBPs in motor neurons. To address this shortcoming, we investigate...

journal_title：Neuroreport

authors： Fahandejsaadi A,Leung E,Rahaii R,Bu J,Geula C

更新日期：2004-03-01 00:00:00

abstract：:This study tested whether adult rat brain stem neurons could respond to growth or trophic factors provided after an extended post-injury period. The number of neurons that regenerated their axon into a peripheral nerve graft following exposure to ciliary neurotrophic factor (CNTF) 8 weeks after a cervical lesion was c...

journal_title：Neuroreport

authors： Houle JD,Ye JH

更新日期：1997-02-10 00:00:00

abstract：:In order to clarify whether neurophysiological profiles affect the performance of brain machine interfaces (BMI), we examined the relationships between amplitudes of movement-related cortical fields (MRCFs) and decoding performances during movement. Neuromagnetic activities were recorded in nine healthy participants d...

journal_title：Neuroreport

authors： Sugata H,Goto T,Hirata M,Yanagisawa T,Shayne M,Matsushita K,Yoshimine T,Yorifuji S

更新日期：2012-01-04 00:00:00

abstract：:Glial cell-line neurotrophic factor (GDNF), a neurotrophic factor with heparin binding affinity, promotes the survival and differentiation of a variety of neuronal cells including dopaminergic neuron. The effect of heparin on GDNF signaling was investigated based on the expression of the tyrosine hydroxyrase (TH) gene...

journal_title：Neuroreport

authors： Tanaka M,Xiao H,Kiuchi K

更新日期：2002-10-28 00:00:00

abstract：:The aim of this study was to define the effects of a potent inhibitor of tyrosine phosphatases, sodium orthovanadate (0.1-100 microM for up to 48 h), on dentate gyrus cells (DGC) in culture. Treatment with 100 microM orthovanadate evoked a delayed form of cell death. To examine the possible involvement of apoptosis in...

journal_title：Neuroreport

authors： Figiel I,Kaczmarek L

更新日期：1997-07-28 00:00:00

abstract：:We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and B6 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels...

journal_title：Neuroreport

authors： Kurth C,Wegerer V,Reulbach U,Lewczuk P,Kornhuber J,Steinhoff BJ,Bleich S

更新日期：2004-02-09 00:00:00

abstract：:The aim was to study whether there is indication of a dissociation in processing of visuospatial and colour information in working memory in humans. Experimental subjects performed visuospatial and colour n-back tasks with and without visuospatial and colour distractive stimuli presented in the middle of the delay per...

journal_title：Neuroreport

authors： Vuontela V,Rämä P,Raninen A,Aronen HJ,Carlson S

更新日期：1999-08-02 00:00:00

abstract：:One approach to understanding the function of presenilin 1 (PS1), is to discover those proteins with which it interacts. Evidence for a function in developmental patterning came from C. elegans, in which a PS homologue was identified by screening for suppressors of a mutation in Notch/lin-12, a gene which specifies ce...

journal_title：Neuroreport

authors： Zhou J,Liyanage U,Medina M,Ho C,Simmons AD,Lovett M,Kosik KS

更新日期：1997-04-14 00:00:00

abstract：:In the retina, the activation of metabotropic glutamate receptors (mGluRs) reduces the toxic effect of N-methyl-D-aspartate (NMDA). We have induced NMDA-mediated excitotoxicity in the adult rat retina by a single intraocular injection of NMDA. The damage that resulted was estimated by assessing the NMDA-induced loss o...

journal_title：Neuroreport

authors： Siliprandi R,Lipartiti M,Fadda E,Arban R,Kozikowski AP,Manev H

更新日期：1994-06-02 00:00:00

abstract：:We have previously reported that antidepressants such as desipramine (DMI) induce axonal regeneration of brain noradrenergic neurons. In the present experiments, the role of phospholipase A2 (PLA2) in the regeneration of brain noradrenergic axons was studied. Symmetrical sites of the rat frontal cortex were pretreated...

journal_title：Neuroreport

authors： Nakamura S

更新日期：1993-04-01 00:00:00

abstract：:Damage to central nervous system white matter is observed following hypoglycemia, raising the possibility that hypoglycemia influences oligodendrocytes and myelination. To examine effects of hypoglycemia on oligodendrocytes and myelin formation, we studied cultured oligodendrocyte precursor cells and cerebellar slice ...

journal_title：Neuroreport

authors： Yan H,Rivkees SA

更新日期：2006-01-23 00:00:00