Auditory neural pathway evaluation on sensorineural hearing loss using diffusion tensor imaging.

abstract：:Net-like structures surrounding several types of neurones contain glycoconjugates which are detectable by lectins specific for N-acetylgalactosamine. Wisteria floribunda agglutinin (WFA) was introduced as a further marker for the visualization of such perineuronal nets, which were also revealed in regions of the rat b...

journal_title：Neuroreport

authors： Härtig W,Brauer K,Brückner G

更新日期：1992-10-01 00:00:00

abstract：:We studied the distribution of phosphorylated tau (p-tau) in neonatal and adult rat cerebrum using monoclonal antibodies that recognize distinct tau epitopes in a phosphorylation-dependent manner. In neonatal cortex, p-tau was detected in the apical dendrites and somata of pyramidal neurons as well as in axons. In adu...

journal_title：Neuroreport

authors： Tashiro K,Hasegawa M,Ihara Y,Iwatsubo T

更新日期：1997-08-18 00:00:00

abstract：:We investigated the brain mechanisms enabling one automatically discriminate phoneme category irrespective of the large inter-speaker variability in the acoustic features of the voices. For this purpose, subjects were presented with 450 different speech stimuli, each uttered by a different speaker, belonging to three ...

journal_title：Neuroreport

authors： Shestakova A,Brattico E,Huotilainen M,Galunov V,Soloviev A,Sams M,Ilmoniemi RJ,Näätänen R

更新日期：2002-10-07 00:00:00

abstract：:Direct currents (DC) applied directly to central nervous system structures produce substantial and long-lasting effects in animal experiments. We tested the functional effects of very weak scalp DC (< 0.5 mA, 7 s) on the human motor cortex by assessing the changes in motor potentials evoked by transcranial magnetic br...

journal_title：Neuroreport

authors： Priori A,Berardelli A,Rona S,Accornero N,Manfredi M

更新日期：1998-07-13 00:00:00

abstract：:We injected neural tracers into the lateral funiculus of the spinal cord in order to relate the sites of origin of the spinal projections from the mesial cortical surface with the cytoarchitectonic organization of this region. We found a close correlation between the origin sites and density of corticospinal projectio...

journal_title：Neuroreport

authors： Luppino G,Matelli M,Camarda R,Rizzolatti G

更新日期：1994-12-20 00:00:00

abstract：:The tonic discharge of rat medial vestibular nucleus (MVN) neurons, and their responsiveness to GABA receptor agonists were investigated in slices prepared from aged rats (24 months old). Aged MVN neurons showed regular spontaneous activity similar to that seen in slices from young adults. However the inhibitory effec...

journal_title：Neuroreport

authors： Him A,Johnston AR,Yau JL,Seckl J,Dutia MB

更新日期：2001-12-21 00:00:00

abstract：:The reduced steroids 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and 3 alpha,21-di-hydroxy-5 alpha-pregnan-20-one (allotetrahydroDOC) are potent ligands of GABAA receptors. This study examined the possible modulatory effect of these metabolites on GABA inhibition of somatostatin release in cultured hypot...

journal_title：Neuroreport

authors： Tapia-Arancibia L,André M,Belmar J,Arancibia S

更新日期：1995-10-02 00:00:00

abstract：:Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD) yet inconsistencies in activation have been reported. One source of variance are individual differences in 5-HTTLPR genotype where the short (S), relative to long (L) allele, corresponds with greater amygdala activation. Howe...

journal_title：Neuroreport

authors： Klumpp H,Fitzgerald DA,Cook E,Shankman SA,Angstadt M,Phan KL

更新日期：2014-08-20 00:00:00

abstract：:Subthalamic nucleus (STN) hyperactivity follows lesions of mesencephalic dopaminergic neurons in animal models of Parkinson's disease. The mechanism leading to sustained STN hyperactivity in parkinsonism is not well understood, but it seems not to depend on the integrity of striato-pallido-subthalamic connections (the...

journal_title：Neuroreport

authors： Murer MG,Ferrario J,Delfino M,Dziewczapolski G,Gershanik OS,Raisman-Vozari R

更新日期：1999-05-14 00:00:00

abstract：:Neurotrophins are promising candidates to slow the progression of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease in which spinal and cortical motoneurons selectively degenerate. In a long-term in vitro model, malonate-induced toxicity and cell death of motoneurons have been demonstrated. Here we stud...

journal_title：Neuroreport

authors： Van Westerlaak MG,Bär PR,Cools AR,Joosten EA

更新日期：2001-05-25 00:00:00

abstract：:With the purpose of mapping representations of the finger and proximal arm in the human primary motor cortex (MI), we measured regional cerebral blood flow (rCBF) in eight right-handed normal volunteers during self-paced finger and proximal arm movements. Each movement activated two different fields in MI, one located...

journal_title：Neuroreport

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Yanagisawa T

更新日期：1995-01-26 00:00:00

abstract：:Deficits in auditory sensory memory at the electrophysiological level as indexed by mismatch negativity and those in auditory verbal memory at the neuropsychological level have been independently demonstrated in previous studies of schizophrenia. We predicted a specific association between these indices in schizophren...

journal_title：Neuroreport

authors： Kawakubo Y,Kasai K,Kudo N,Rogers MA,Nakagome K,Itoh K,Kato N

更新日期：2006-07-17 00:00:00

abstract：:Lesions involving the dorsolateral prefrontal lobes may produce deficits on conceptual reasoning (CR) tasks in humans. Such deficits can also occur with subcortical lesions involving the basal ganglia, thalamus, or cerebellum, suggesting a common, yet widespread, neural network supporting this executive function. Here...

journal_title：Neuroreport

authors： Rao SM,Bobholz JA,Hammeke TA,Rosen AC,Woodley SJ,Cunningham JM,Cox RW,Stein EA,Binder JR

更新日期：1997-05-27 00:00:00

abstract：:The pathogenesis of amyotrophic lateral sclerosis remains poorly understood, but microglial and astroglial activation are thought to contribute to motor neuron death. Evidence suggests that matrix metalloproteinase-9 (MMP-9) is a mediator of this deleterious effect. In this study, we evaluated the effect of MMP-9 on t...

journal_title：Neuroreport

authors： Dewil M,Schurmans C,Starckx S,Opdenakker G,Van Den Bosch L,Robberecht W

更新日期：2005-03-15 00:00:00

abstract：:We investigated the spatio-temporal brain activity on the time scale of several milliseconds related to the mental rotation task requiring judgements of hand orientation, using a whole-cortex MEG (magnetoencephalography) system. Neuronal activity in the visual cortex was observed approximately 100-200 ms from stimulus...

journal_title：Neuroreport

authors： Kawamichi H,Kikuchi Y,Endo H,Takeda T,Yoshizawa S

更新日期：1998-04-20 00:00:00

abstract：:Expression of the lipophilic ligand transporter, apolipoprotein D (apoD) by primary astrocyte cultures derived from neonatal mouse brain was investigated. Western blot analysis of cell lysates and media showed that apoD is constitutively secreted by astrocytes with little intracellular storage. The secreted apoD float...

journal_title：Neuroreport

authors： Patel SC,Asotra K,Patel YC,McConathy WJ,Patel RC,Suresh S

更新日期：1995-03-07 00:00:00

abstract：:The neural foundation of age-related declines in prospective memory was explored using event-related brain potentials (ERPs). Consistent with previous research, a decline in the efficiency of prospective memory was observed in older adults that reflected a decrease in veridical prospective responses and an increase in...

journal_title：Neuroreport

authors： West R,Covell E

更新日期：2001-09-17 00:00:00

abstract：:Music is an essential communication tool that can convey emotional information. Segmentation of a sound stream of music at event boundaries is necessary for identification and extraction of musical context and features. To investigate recognition of music termination structure, or cadence, we composed music sequences ...

journal_title：Neuroreport

authors： Hoshi-Shiba R,Furukawa K,Okanoya K

更新日期：2014-07-09 00:00:00

abstract：:The expression pattern of metabotropic glutamate receptor 1alpha (mGluR1alpha) was immunohistochemically investigated in substantia nigra dopaminergic neurons of the macaque monkey. In normal monkeys, mGluR1alpha immunoreactivity was weakly observed in the dorsal tier of the substantia nigra pars compacta (SNc-d) wher...

journal_title：Neuroreport

authors： Kaneda K,Imanishi M,Nambu A,Shigemoto R,Takada M

更新日期：2003-05-23 00:00:00

abstract：:Impaired print tuning in dyslexia has been shown in alphabetic languages; whether we can observe the same in a nonalphabetic language such as Chinese is still questionable. The present study investigated the N170 component in response to Chinese words versus nonword pseudo-words in 10-year-old children with developmen...

journal_title：Neuroreport

authors： Zhou L,Yan X

更新日期：2018-10-17 00:00:00

abstract：:Results from a computer model of a thalamic network predict that agents augmenting GABA(A)-mediated inhibition in the reticular thalamic (RE) nucleus will be antiepileptic or desynchronizing. This provides support for the hypothesis that antiepileptics like benzodiazepines may exert their effects through an isolated i...

journal_title：Neuroreport

authors： Thomas E,Lytton WW

更新日期：1998-03-09 00:00:00

abstract：:Alpha-Synuclein is a major component of neuronal and glial cytoplasmic inclusions in multiple system atrophy (MSA), one of the alpha-synucleinopathies. Recent studies have shown that beta-synuclein, a homolog of alpha-synuclein, inhibits alpha-synuclein aggregation in vitro. We immunohistochemically examined the MSA b...

journal_title：Neuroreport

authors： Mori F,Nishie M,Yoshimoto M,Takahashi H,Wakabayashi K

更新日期：2003-10-06 00:00:00

abstract：:The amino acid glycine is an inhibitory neurotransmitter in the spinal cord, brain stem, and vertebrate retina. The effective synaptic concentrations of glycine are regulated by at least two transporters: glycine transporter 1 and glycine transporter 2. Here, we show retinal expression of glycine transporter 1 by in-s...

journal_title：Neuroreport

authors： Peña-Rangel MT,Riesgo-Escovar JR,Sánchez-Chávez G,Salceda R

更新日期：2008-08-27 00:00:00

abstract：:Elevations of cytosolic free Ca2+ concentration ([Ca2+]i) induced by addition of ATP have been compared in rat dorsal horn neurones in slices and after their isolation. ATP application induced in neurones in situ a rise of [Ca2+]i by 201 +/- 12 nM. In Ca2+-free external solution the rise was 156 +/- 14 nM (n = 45 of 7...

journal_title：Neuroreport

authors： Kruglikov I,Shutov L,Potapenko E,Voitenko N,Kostyuk P

更新日期：2001-11-16 00:00:00

abstract：:We examined the electrophysiological correlates of the processing of social exclusion and inclusion by using a modified version of the Cyberball paradigm. Exclusion was found to be associated with a significant increase in the P3 complex. The frontal-central P3a was primarily related to the affective processing of rej...

journal_title：Neuroreport

authors： Gutz L,Küpper C,Renneberg B,Niedeggen M

更新日期：2011-06-22 00:00:00

abstract：:This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not g...

journal_title：Neuroreport

authors： Murrell W,Bushell GR,Livesey J,McGrath J,MacDonald KP,Bates PR,Mackay-Sim A

更新日期：1996-04-26 00:00:00

abstract：:Two patterns of neuronal firing, bursting and regular spiking, are observed in the somatosensory cortex of anesthetized rats. The effects of excitatory amino acid receptor agonists and antagonists on these discharge types have been examined in vivo, in order to assess their involvement in the generation of such firing...

journal_title：Neuroreport

authors： Kobayashi T,Nagao T,Fukuda H,Hicks TP,Oka JI

更新日期：1993-06-01 00:00:00

abstract：:The ability to attribute mental states to others ('theory of mind') pervades normal social interaction and is impaired in autistic individuals. In a previous positron emission tomography scan study of normal volunteers, performing a 'theory of mind' task was associated with activity in left medial prefrontal cortex. W...

journal_title：Neuroreport

authors： Happé F,Ehlers S,Fletcher P,Frith U,Johansson M,Gillberg C,Dolan R,Frackowiak R,Frith C

更新日期：1996-12-20 00:00:00

abstract：:The distribution of the enzyme NADPH diaphorase in the region of the periaqueductal gray (PAG) was studied in the rat, rabbit, cat, monkey and human. In each species, the enzyme labelled a small band of neurones located below the level of the aqueduct and directly above the supraoculomotor gray in the middle of the an...

journal_title：Neuroreport

authors： Carrive P,Paxinos G

更新日期：1994-11-21 00:00:00

abstract：:We examined whether 53 adult non-aphasic patients with either left (22) or right temporal lobe lesions (31) demonstrate dissociable patterns of hemispheric asymmetries in category-specific word fluency tasks. The patients were asked to articulate as many appropriate words as possible within 60 or 90 s in response to s...

journal_title：Neuroreport

authors： Jokeit H,Heger R,Ebner A,Markowitsch HJ

更新日期：1998-07-13 00:00:00