Transient expression of PKC gamma mRNA in cerebellar granule cells during rat brain development.

abstract：:Sex differences in event-related potentials were examined in 23 women and 24 men during a mental rotation task. We found an early (130-400 ms) and a late (400-700 ms) ERP mental rotation effect. The late rotation effect, which is thought to indicate the onset of the cognitive process of mental rotation, emerged about ...

journal_title：Neuroreport

authors： Gootjes L,Bruggeling EC,Magnée T,Van Strien JW

更新日期：2008-02-12 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) was used in 17 normal individuals to modulate vestibulo-ocular reflex (VOR) and self-motion perception rotational thresholds. The electrodes were applied over the temporoparietal junction bilaterally. Both vestibular nystagmic and perceptual thresholds were increased duri...

journal_title：Neuroreport

authors： Kyriakareli A,Cousins S,Pettorossi VE,Bronstein AM

更新日期：2013-10-02 00:00:00

abstract：:We investigated the role of melatonin in the induction of gastric lesions induced by water immersion restraint stress or centrally administered thyrotropin-releasing hormone (TRH). Melatonin (0.1-1 ng) injected intracisternally (i.c) 30 min prior to stress dose-dependently inhibited the induction of gastric lesions by...

journal_title：Neuroreport

authors： Kato K,Murai I,Asai S,Komuro S,Matsuno Y,Matsukawa Y,Kurosaka H,Iwasaki A,Ishikawa K,Arakawa Y

更新日期：1997-07-07 00:00:00

abstract：:Whole-cell recordings in voltage-clamp mode were performed on acutely isolated neurones from rat neocortex and neostriatum to examine the effects of the anticonvulsant phenytoin on a non-inactivating (persistent) Na+ current (INaP). INaP was chosen because it enhances neuronal excitability near firing threshold, which...

journal_title：Neuroreport

authors： Chao TI,Alzheimer C

更新日期：1995-09-11 00:00:00

abstract：:Numerous studies have shown that the cerebellum is involved in classical conditioning of specific aversive reactions. Only few studies, however, have examined the exact localization of cerebellar areas involved in the control of unconditioned reflex responses. The present study investigated cerebellar areas, which are...

journal_title：Neuroreport

authors： Maschke M,Erichsen M,Drepper J,Jentzen W,Müller SP,Kolb FP,Diener HC,Timmann D

更新日期：2002-12-03 00:00:00

abstract：:Recent studies have shown the nutrient-sensing systems transmitting nutritive information from the gut to the brain. However neural activity evoked by ingested dietary nutrients has not been investigated adequately. Using functional magnetic resonance imaging, we demonstrated that rat forebrain responded to intragastr...

journal_title：Neuroreport

authors： Tsurugizawa T,Kondoh T,Torii K

更新日期：2008-07-16 00:00:00

abstract：:In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the pos...

journal_title：Neuroreport

authors： Giménez M,Junqué C,Narberhaus A,Caldú X,Segarra D,Vendrell P,Bargalló N,Mercader JM

更新日期：2004-03-22 00:00:00

abstract：:Nerve growth factor (NGF) is trophic to sensory and sympathetic fibres, and ciliary neurotrophic factor (CNTF) to motoneurones, in animal models of peripheral nerve injury: NGF excess produces hyperalgesia. In this first study of injured human nerves and sensory ganglia, we quantified and localized endogenous NGF and ...

journal_title：Neuroreport

authors： Anand P,Terenghi G,Birch R,Wellmer A,Cedarbaum JM,Lindsay RM,Williams-Chestnut RE,Sinicropi DV

更新日期：1997-05-27 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine the expression level of immunoproteasome and its clinical significance in glioma preliminarily. Furthermore, we studied the function and molecular mechanism of proteasome inhibitor ONX 0912 on glioma cell. MATERIALS AND METHODS:The expression of immunoproteasome in gli...

journal_title：Neuroreport

authors： Min L,Zeng X,Li B,Tao B,Shi J,Zhang W,Sun Q,Jing C,Wang X

更新日期：2019-10-16 00:00:00

abstract：:The orientation biases seen in the responses of neurones of the dorsal lateral geniculate nucleus (dLGN) can be reduced by the local application of the GABA antagonist, bicuculline methiodide. This fact was exploited to investigate whether these biases are important for cortical orientation selectivity by measuring th...

journal_title：Neuroreport

authors： Vidyasagar TR

更新日期：1992-02-01 00:00:00

abstract：:An exaggerated startle response caused by mutations of the alpha 1 subunit gene of the inhibitory glycine receptor (GLRA1) is the key symptom of human hyperekplexia or startle disease. The recessive mouse mutant spasmodic (spd) carries a missense mutation in the corresponding murine Glra1 gene which reduces the affini...

journal_title：Neuroreport

authors： Koch M,Kling C,Becker CM

更新日期：1996-02-29 00:00:00

abstract：:Melatonin has been shown to exert potent antinociception but the sites and mechanisms of action underlying this effect have not yet been clarified. The effect of melatonin on spinal cord nociceptive transmission was studied in rats by assessing wid-up activity in a C-fiber reflex responses paradigm evoked by repetitiv...

journal_title：Neuroreport

authors： Laurido C,Pelissie T,Soto-Moyano R,Valladares L,Flores F,Hernández A

更新日期：2002-01-21 00:00:00

abstract：:The hypothesis of a general (i.e. cross-modal) temporal processing deficit in dyslexia was tested by examining rapid processing in both the auditory and the visual system in the same children with dyslexia. Participants were 10- to 12-year-old dyslexic readers and age-matched normal reading controls. Psychophysical th...

journal_title：Neuroreport

authors： Van Ingelghem M,van Wieringen A,Wouters J,Vandenbussche E,Onghena P,Ghesquière P

更新日期：2001-11-16 00:00:00

abstract：:Regulation of CNS distribution of the human immunodeficiency virus (HIV) protease inhibitor saquinavir may involve ATP-dependent membrane-bound efflux transport proteins that are expressed in several brain cellular compartments. We recently characterized molecular and functional expression of one such transporter, mul...

journal_title：Neuroreport

authors： Dallas S,Ronaldson PT,Bendayan M,Bendayan R

更新日期：2004-05-19 00:00:00

abstract：:It is often claimed that binding information across sensory modalities leads to coherent, unitary mental representations. The dramatic illusions experienced as a result of intersensory conflict, such as the McGurk effect, are often attributed to a propensity of the perceptual system to impose multisensory coherence on...

journal_title：Neuroreport

authors： Soto-Faraco S,Alsius A

更新日期：2007-03-05 00:00:00

abstract：:Two well-known appetite-regulatory peptides, leptin and cocaine- and amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet known how they interact in the nucleus accumbens, an important region mediating the rewarding effects of drugs of abuse. Using th...

journal_title：Neuroreport

authors： Cho BR,Yoon HS,Kim WY,Vezina P,Kim JH

更新日期：2017-08-02 00:00:00

abstract：:beta-N-methylamino-L-alanine (L-BMAA) is an excitotoxin whose neurodegenerative effects are associated with its agonist properties at the N-methyl-D-aspartate (NMDA) receptor. We measured the effects of L-BMAA on inositol phosphate (InsP) formation in primary cultured striatal neurons. This culture is almost devoid of...

journal_title：Neuroreport

authors： Manzoni OJ,Prezeau L,Bockaert J

更新日期：1991-10-01 00:00:00

abstract：:Plasminogen activators (PAs) have been suggested to play a role in neuronal migration and glial cell proliferation in the developing CNS. Less is known, however, about the role of PAs in the mature nervous system. To elucidate the role of tissue type plasminogen activator (tPA) in the nervous system we used in situ hy...

journal_title：Neuroreport

authors： Yuguchi T,Kohmura E,Yamada K,Otsuki H,Sakaki T,Yamashita T,Nonaka M,Sakaguchi T,Wanaka A,Hayakawa T

更新日期：1997-01-20 00:00:00

abstract：:Increasing evidence suggests a neurotransmitter role for NO in the mammalian CNS. We have now studied the behavioural and electrocortical (ECoG) profile of rats injected into the lateral cerebral ventricle (ICV) with L-arginine (L-arg), the endogenous donor of the guanidino group from which NO physiologically originat...

journal_title：Neuroreport

authors： Mollace V,Bagetta G,Nisticò G

更新日期：1991-05-01 00:00:00

abstract：:We investigated whether in vivo excitotoxicity was mediated by a mechanism of programmed cell death called apoptosis. Neurotoxic doses of kainic acid (1.2 nmol) and quinolinic acid (120 nmol) were unilaterally injected in the dorsal hippocampus of anesthetized rats. Eight or 16 h later the animals were killed and DNA ...

journal_title：Neuroreport

authors： Ignatowicz E,Vezzani AM,Rizzi M,D'Incalci M

更新日期：1991-11-01 00:00:00

abstract：:GABAA receptor-independent effects of benzodiazepine receptor (BZ-R) agonists on calcium and barium spikes were recorded intracellularly in the presence of bicuculline from CA3 hippocampal cells of young and adult rats. Zolpidem (omega 1 BZ-R agonist), had no effects in young animals but decreased calcium and barium s...

journal_title：Neuroreport

authors： Rovira C,Ben-Ari Y

更新日期：1994-10-27 00:00:00

abstract：:Gastrin-releasing peptide plays an important role in regulating the advanced functions of the brain including emotional behavior, learning and memory. What's more, gastrin-releasing peptide levels are also associated with the central nervous system diseases. Our previous study proposed that intraperitoneal injection o...

journal_title：Neuroreport

authors： Yao Y,Yang X,Wang Z

更新日期：2019-10-16 00:00:00

abstract：:Fragile X syndrome is a neurodevelopmental disorder caused by a trinucleotide (CGG) hyperexpansion in the FMR1 gene, functionally silencing transcription of the fragile X mental retardation protein (FMRP). This disorder is characterized by impaired cognition, communication, and social behavior. The aim of this study w...

journal_title：Neuroreport

authors： Reynolds CD,Nolan SO,Jefferson T,Lugo JN

更新日期：2016-12-14 00:00:00

abstract：:The serum-free mouse embryo (SFME) cell line, derived from 16-day-old mouse embryos in medium in which serum was replaced by growth factors and other supplements, has been cultured for more than 200 generations. SFME cells are nontumorigenic, lack gross chromosomal abnormalities, and display characteristics of CNS pro...

journal_title：Neuroreport

authors： Loo DT,Althoen MC,Cotman CW

更新日期：1994-08-15 00:00:00

abstract：:Optical imaging of rat barrel cortex has provided detailed spatio-temporal maps of functional cortical architecture. We describe an event-related procedure (ERP) for optical imaging based on selective signal averaging as reported by Burock et al., using an anti-correlative pseudo-random event sequence. The sequence us...

journal_title：Neuroreport

authors： Martindale J,Berwick J,Johnston D,Jones M,Zheng Y,Coffey P,Paley M,Mayhew J

更新日期：2000-07-14 00:00:00

abstract：:We examined the effect of stimulus interruption on dual component field EPSPs in the hippocampal CA1 region. Resuming test stimulation at 0.1 Hz after 10-60 min silent periods led to an increase of the response followed by a decline, involving AMPA and NMDA components to a similar extent. Similar changes were seen whe...

journal_title：Neuroreport

authors： Niu YP,Xiao MY,Karpefors M,Wigström H

更新日期：1999-04-06 00:00:00

abstract：:Single unit recordings were made from the ventral posterior lateral thalamus of anaesthetized rats to characterize responses to the activation of new receptive fields induced by either local anaesthesia or amputation. Receptive fields confined to single digits were identified and evoked unit responses to the stimulati...

journal_title：Neuroreport

authors： Shin HC,Park S,Son J,Sohn JH

更新日期：1995-12-29 00:00:00

abstract：:This study used event-related functional magnetic resonance imaging to investigate the neural basis underlying the sequential involvement of syntactic processing in the course of sentence comprehension. In experiments, a noun, case particle, and verb were presented one by one, constituting simple sentences in Japanese...

journal_title：Neuroreport

authors： Ogawa K,Ohba M,Inui T

更新日期：2007-09-17 00:00:00

abstract：:In situ hybridization and Northern blotting were used to study the expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat brain following photochemical stroke. A focal thrombotic lesion of the sensorimotor cortex was produced by intravenously injecting the light-sensitive dye rose bengal and exposing t...

journal_title：Neuroreport

authors： Comelli MC,Seren MS,Guidolin D,Manev RM,Favaron M,Rimland JM,Canella R,Negro A,Manev H

更新日期：1992-06-01 00:00:00

abstract：:We investigated some in vitro pharmacological properties of a novel human dopamine D2-like receptor antagonist, YM-50001 [(R)-5-chloro-4-cyclopropylacarbonylamino-2-methoxy-N-[1-(3-methox ybenzyl)- 3-pyrrolidinyl]benzamide monooxalate]. Receptor binding studies revealed that YM-50001 had a potent affinity for human D4...

journal_title：Neuroreport

authors： Hidaka K,Tada S,Matsumoto M,Ohmori J,Maeno K,Yamaguchi T

更新日期：1996-11-04 00:00:00