N-methyl D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitors.

abstract：:Our previous studies have shown that Panax notoginseng saponins (PNS) play a protective role in learning dysfunction of Alzheimer's disease, inhibit the deposition of Aβ1-40 and Aβ1-42, and reduce the content of App in the brain of SAMP8. In this study, we aimed to investigate the effects of PNS on α, β, and γ secreta...

journal_title：Neuroreport

authors： Huang J,Wu D,Wang J,Li F,Lu L,Gao Y,Zhong Z

更新日期：2014-01-22 00:00:00

abstract：:NMR signal intensities in five regions of the midsagittal corpus callosum were measured in autism patients and normal controls. An age-related increase in signal was observed in the anterior regions in both groups. No significant differences in intensity were detected between the groups. The finding of normal myelinat...

journal_title：Neuroreport

authors： Belmonte M,Egaas B,Townsend J,Courchesne E

更新日期：1995-06-19 00:00:00

abstract：:The present study examined the effects of cocaine-regulated and amphetamine-regulated transcript peptide (CARTp) fragment 55-102, on N-methyl-D-aspartate (NMDA)-mediated nociceptive transmission in vivo and in vitro. In-vivo experiments were conducted in Sprague-Dawley rats to evaluate the effects of CARTp on thermal ...

journal_title：Neuroreport

authors： Hsun Lin H,Chiu HY,Lai CC

更新日期：2005-02-28 00:00:00

abstract：:The distribution of the enzyme NADPH diaphorase in the region of the periaqueductal gray (PAG) was studied in the rat, rabbit, cat, monkey and human. In each species, the enzyme labelled a small band of neurones located below the level of the aqueduct and directly above the supraoculomotor gray in the middle of the an...

journal_title：Neuroreport

authors： Carrive P,Paxinos G

更新日期：1994-11-21 00:00:00

abstract：:The steady-state visual evoked potential (SSVEP) is a powerful tool to study basic perceptual functions in the human electroencephalogram (EEG) (e.g. selective attention). The present study aimed at finding support for the SSVEP's sensitivity to higher cognitive functions (e.g. memory). We tagged pictures of meaningle...

journal_title：Neuroreport

authors： Martens U,Gert AL,Gruber T

更新日期：2012-04-18 00:00:00

abstract：:The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed befo...

journal_title：Neuroreport

authors： Ohn SH,Park CI,Yoo WK,Ko MH,Choi KP,Kim GM,Lee YT,Kim YH

更新日期：2008-01-08 00:00:00

abstract：:Chronic ethanol (EtOH) exposure can cause intracellular Ca overload by stimulating calcium channel receptors and trigger apoptosis of neurons. NCX3 may play a cytoprotective role in intracellular Ca excretion. In this study, the effect of EtOH on NCX3 was analyzed by observing NCX3 expression in the hippocampus of chr...

journal_title：Neuroreport

authors： Wang C,Wang X,Li Y,Xia Z,Liu Y,Yu H,Xu G,Wu X,Zhao R,Zhang G

更新日期：2019-04-10 00:00:00

abstract：:Transplanted olfactory ensheathing cells (OECs) have previously been demonstrated to support axonal growth and myelination in the adult rat CNS. Here, the capacity of donor OECs to control the direction of axonal regeneration has been investigated following transplantation, as elongated columns, into the thalamus of a...

journal_title：Neuroreport

authors： Pérez-Bouza A,Wigley CB,Nacimiento W,Noth J,Brook GA

更新日期：1998-09-14 00:00:00

abstract：:We used an electrophysiological marker of linguistic discordance, the N400 wave, to investigate how linguistic and pseudo-linguistic stimuli are categorised during sleep as compared to waking. During wakefulness, signs of discordance detection were, as expected, greater for pseudo-words than for real but semantically ...

journal_title：Neuroreport

authors： Perrin F,Bastuji H,Garcia-Larrea L

更新日期：2002-07-19 00:00:00

abstract：:Inflammatory and immune responses are known to be involved in the pathogenesis of Alzheimer's disease (AD). NF-kappaB is a major transcription factor that plays a central role in the inflammatory and immune responses and is regulated by I-kappaB through an autoregulatory feedback system. Southwestern immunohistochemis...

journal_title：Neuroreport

authors： Yoshiyama Y,Arai K,Hattori T

更新日期：2001-08-28 00:00:00

abstract：:The phonemic structure of the maternal language determines the way of perceiving speech signals. A typical example is that native Japanese listeners map two English phonemes, /r/ and /l/, onto the same /R/. This perceptual assimilation of speech sounds has been associated with the left and/or right posterior perisylvi...

journal_title：Neuroreport

authors： Hara NF,Nakamura K,Kuroki C,Takayama Y,Ogawa S

更新日期：2007-10-08 00:00:00

abstract：:For the majority of neurones in cat striate cortex, the response to an optimal stimulus presented to one eye is suppressed when a stimulus of substantially different orientation is presented to the other eye. In order to determine the true orientational tuning of the underlying inhibitory interactions in the absence o...

journal_title：Neuroreport

authors： Sengpiel F,Freeman TC,Blakemore C

更新日期：1995-11-13 00:00:00

abstract：:In the absence of vision of the limb, movements toward a visual target exhibit substantial errors which are considered to originate mainly in the visuomotor transformation process. To determine the time-dependent property of human visuomotor transformation, we investigated the error sequences in movements toward visua...

journal_title：Neuroreport

authors： Miyazaki M,Nakajima Y,Kadota H,Chitose K,Ohtsuki T,Kudo K

更新日期：2004-05-19 00:00:00

abstract：:We recorded multiple unit activities of the CA1 region of the intermediate hippocampus and prelimbic area of the prefrontal cortex, and evoked responses in the prefrontal cortex by hippocampal stimulation in urethane-anesthetized rats. The multiple unit activities between these regions showed significant peaks of cros...

journal_title：Neuroreport

authors： Fujiwara SE,Akema T,Izaki Y

更新日期：2010-10-27 00:00:00

abstract：:The effects of intracerebroventricular (i.c.v.) administration of galanin on plasma growth hormone (GH) concentrations and its possible mechanism of action have been examined in sheep. Galanin administration icv resulted in a dose-dependent increase in plasma GH concentrations (p < 0.01). Concurrent administration of ...

journal_title：Neuroreport

authors： Spencer GS,Berry CJ,Bass JJ

更新日期：1994-01-12 00:00:00

abstract：:Subcortical visual inputs to motion-selective cortex in primates survive after damage to the primary visual cortex (area 17/V1). Activation of human motion cortex was examined using scalp electrodes in a V1-damaged hemianope. Blind field motion-onset visual evoked potentials (VEPs) shared many of the characteristics a...

journal_title：Neuroreport

authors： Benson PJ,Guo K,Hardiman MJ

更新日期：1999-11-26 00:00:00

abstract：:To study the penetration of magnesium ions from blood into brain tissue, magnesium content in serum and hippocampus of normal and of excitotoxically affected rats was estimated after a single subcutaneous injection of magnesium sulphate (600 mg kg-1). In normal rats Mg2+ levels in serum rose from 1 to 6 mM, while that...

journal_title：Neuroreport

authors： Rothe F,Wolf G,Fischer S,Hass P,Keilhoff G,Abicht K

更新日期：1993-02-01 00:00:00

abstract：:The event-related potential technique was used to investigate the time course and scalp-potential topography for the numerical distance effect in a number-matching task. Twenty undergraduates judged whether a number matched or did not match another number presented 1.5 s earlier. Compared with number pairs with a 'sma...

journal_title：Neuroreport

authors： Zhou X,Chen C,Dong Q,Zhang H,Chen C,Qiao S,Zhao H,Jiang T,Guo Y

更新日期：2006-07-17 00:00:00

abstract：:We investigated the reactive cytoskeletal changes following physical damage to axons in the rodent neocortex and compared these with the earliest neuronal alterations seen in Alzheimer's disease (AD). Insertion of a 25 gauge needle into the rodent somatosensory cortex resulted in ring- and club-like axonal changes cha...

journal_title：Neuroreport

authors： King CE,Jacobs I,Dickson TC,Vickers JC

更新日期：1997-05-06 00:00:00

abstract：:Latexin is a novel 29 kDa protein which is expressed in a subpopulation of neurones in the lateral cerebral cortex of adult rats. Here, we report the distribution of immunohistochemically detectable latexin in the rat brain during early phases of development. Latexin was first detected at embryonic day 11 (E11) along ...

journal_title：Neuroreport

authors： Takiguchi-Hayashi K,Arimatsu Y

更新日期：1995-01-26 00:00:00

abstract：:Recent studies on cerebrospinal fluid (CSF) homeostasis emphasize the importance of water flux through the pericapillary (Virchow-Robin) space for both CSF production and reabsorption (Oreskovic and Klarica hypothesis), and challenge the classic CSF circulation theory, which proposes that CSF is primarily produced by ...

journal_title：Neuroreport

authors： Igarashi H,Tsujita M,Kwee IL,Nakada T

更新日期：2014-01-08 00:00:00

abstract：:Opioid-receptor-like I (ORLI) receptors, ORLI mRNA and nociceptin are particularly abundant in the limbic system and in central monoaminergic areas, brain regions involved in mood regulation and response to antidepressants. To analyse whether ORLI receptors adaptations occur during the first 3 weeks of an antidepressa...

journal_title：Neuroreport

authors： Vilpoux C,Naudon L,Costentin J,Leroux-Nicollet I

更新日期：2002-01-21 00:00:00

abstract：:It has been previously demonstrated that members of the neurotrophin family may prevent death of motoneurones following axotomy. Here we report that the expression of mRNA for full-length trkB, which is a signal transducing receptor for BDNF and NT-4, increases transiently in spinal motoneurones after axotomy in adult...

journal_title：Neuroreport

authors： Piehl F,Frisén J,Risling M,Hökfelt T,Cullheim S

更新日期：1994-02-24 00:00:00

abstract：:The present study explored duration mismatch negativity (MMN) reduction in schizophrenia. Duration MMN studies usually employ tones of very short duration (< 200 ms). For stimuli < 200 ms in duration, an increment in duration is accompanied by an increase in perceived loudness. It was previously proposed that the effe...

journal_title：Neuroreport

authors： Todd J,Michie PT,Jablensky AV

更新日期：2001-12-21 00:00:00

abstract：:We screened proteins for interaction with presenilin (PS) 1, and cloned the full-length cDNA of human delta-catenin, which encoded 1225 amino acids. Yeast two-hybrid assay, GST binding assay and immunoprecipitation demonstrated that delta-catenin interacted with a hydrophilic loop region in the endoproteolytic C-termi...

journal_title：Neuroreport

authors： Tanahashi H,Tabira T

更新日期：1999-02-25 00:00:00

abstract：:This study aimed to evaluate the potential of bone marrow stromal cells for treatment of inner ear diseases. Autologous marrow cells labeled with Dil were implanted into the inner ear of five gentamicin-treated chinchillas. Histological analysis 3 weeks later revealed robust survival of grafted marrow cells in multipl...

journal_title：Neuroreport

authors： Naito Y,Nakamura T,Nakagawa T,Iguchi F,Endo T,Fujino K,Kim TS,Hiratsuka Y,Tamura T,Kanemaru S,Shimizu Y,Ito J

更新日期：2004-01-19 00:00:00

abstract：:In the present study the effects of intracerebroventricular (ICV) administration of baclofen (0.1-5.0 nmol) was investigated on food intake in non-fasted rats. Baclofen (1.0, 2.5 and 5.0 nmol) increased food consumption in a dose-related manner during the first 15-30 min after administration. The effects of baclofen (...

journal_title：Neuroreport

authors： Ebenezer IS

更新日期：1990-09-01 00:00:00

abstract：:Subpopulations of olfactory receptor neurons, which are dispersed throughout the olfactory neuroepithelium, express specific cell surface carbohydrates and project to discrete regions of the olfactory bulb. Cell surface carbohydrates such as N-acetyl-lactosamine have been postulated to mediate sorting and selective fa...

journal_title：Neuroreport

authors： Puche AC,Bartlett PF,Key B

更新日期：1997-10-20 00:00:00

abstract：:The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

journal_title：Neuroreport

authors： O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

更新日期：2000-11-27 00:00:00

abstract：:The purpose of the present study was to determine the cortical areas contributing to the influence of the previous movement on the current movement. Right-handed healthy human participants abducted and then adducted the left index finger in response to a start cue. Twenty consecutive trials with 10 s intertrial interv...

journal_title：Neuroreport

authors： Oda H,Sawaguchi Y,Kunimura H,Kawasaki T,Hiraoka K

更新日期：2020-12-30 00:00:00