Effects of movement on somatosensory N20m fields and high-frequency oscillations.

abstract：:Oleic acid, a cis-unsaturated free fatty acid, is proposed to be involved in the protein kinase C (PKC) activation pathway. Its biological actions, however, have not been well-characterized. We examined the effects of oleic acid on acetylcholine (ACh)-gated channel currents using Torpedo nicotinic ACh receptors expres...

journal_title：Neuroreport

authors： Nishizaki T,Ikeuchi Y,Matsuoka T,Sumikawa K

更新日期：1997-02-10 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP-22) gene which results in abnormal myelination of the peripheral nervous system. However, the clinical symptoms observed in the mutant suggest abnormalities in the central nervous system. Using the Northern blot te...

journal_title：Neuroreport

authors： Bascles L,Bonnet J,Garbay B

更新日期：1994-06-02 00:00:00

abstract：:Melatonin, a hormone from the pineal gland, was tested for its anticonvulsant effects in male gerbils. Daily administration of melatonin (25 micrograms injection-1, s.c.) for ten weeks reduced the number and severity of seizures (total convulsion score: 7.67 +/- 1.83 in controls vs 2.47 +/- 0.90 in melatonin-injected ...

journal_title：Neuroreport

authors： Champney TH,Champney JA

更新日期：1992-12-01 00:00:00

abstract：:BC200 is a long noncoding RNA expressed at high levels in the Alzheimer's disease (AD), and blocking of BC200 by siRNA is assumed to be an effective method for various disease therapy. We have established an AD cell model overexpressing amyloid β-peptide (Aβ)1-42 to observe the effects of BC200 on the cell viability a...

journal_title：Neuroreport

authors： Li H,Zheng L,Jiang A,Mo Y,Gong Q

更新日期：2018-09-05 00:00:00

abstract：:Glutamatergic excitotoxicity has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, activation of metabotropic glutamate receptors (mGluRs) is neuroprotective in several paradigms. We therefore tested the effect of selective mGluR agonists on cultured chick embryonic motor neurons. Ac...

journal_title：Neuroreport

authors： Anneser JM,Horstmann S,Weydt P,Borasio GD

更新日期：1998-06-22 00:00:00

abstract：:Alpha-Synuclein is a major component of neuronal and glial cytoplasmic inclusions in multiple system atrophy (MSA), one of the alpha-synucleinopathies. Recent studies have shown that beta-synuclein, a homolog of alpha-synuclein, inhibits alpha-synuclein aggregation in vitro. We immunohistochemically examined the MSA b...

journal_title：Neuroreport

authors： Mori F,Nishie M,Yoshimoto M,Takahashi H,Wakabayashi K

更新日期：2003-10-06 00:00:00

abstract：:Neuropathological and neuroimaging studies indicate a decrease in Purkinje cell (PC) density in the cerebellum of autistic patients and rodent models of autism. Autism is far more prevalent in males than females, and sex-specific properties of PCs have been reported recently. We investigated the differential sensitivi...

journal_title：Neuroreport

authors： Roux S,Bailly Y,Bossu JL

更新日期：2019-01-16 00:00:00

abstract：:The pattern of distribution and co-localization of nitric oxide synthase (NOS) and quinacrine fluorescence (indicative of vesicular adenosine 5'-triphosphate, ATP), and co-localization of NADPH-diaphorase (NADPH-d) activity and NOS-immunoreactivity in the myenteric plexus of pre-term human fetal (6-17 weeks of gestati...

journal_title：Neuroreport

authors： Belai A,Burnstock G

更新日期：2000-01-17 00:00:00

abstract：:NMDA receptors (NR) are important in many neurological processes. Using a large series of human brain tissue, we show that the distribution of NR2A/B immunoreactivity varies according to position along a gyrus. For pyramidal neurons in laminae II and III, immunoreactivity is most marked at gyral crown and gyral lips, ...

journal_title：Neuroreport

authors： Sisodiya SM,Heffernan J,Harrison PJ,Squier MV,Thom M

更新日期：2000-08-03 00:00:00

abstract：:Bioelectric activity of CO2-sensitive, ventrolateral medullary neurons (VLN(CS)) in organotypic cultures from the obex level of newborn rats was tested during changes of the intracellular pH (pHi) measured in BCECF-AM loaded cultures. Hypercapnia (pCO2 80-100 mmHg) reduced pHi by 0.15 +/- 0.06 units and stimulated neu...

journal_title：Neuroreport

authors： Wiemann M,Baker RE,Bonnet U,Bingmann D

更新日期：1998-01-05 00:00:00

abstract：:We investigated the expression for fibroblast growth factor-2 (FGF-2), in cultured rat cerebellar granule cells and its modulation by Ca2+ regulating agents. There were no significant differences in the levels of FGF-2 mRNA in cells cultured in high vs low K+. The expression of the trophic factor is induced by Ca2+ en...

journal_title：Neuroreport

authors： Roceri M,Molteni R,Racagni G,Riva MA

更新日期：2000-11-09 00:00:00

abstract：:To assess the effect of genetic factors on sporadic Parkinson disease, we performed a case-control study of a variant (G2385R) in Leucine-Rich Repeat kinase 2 among the Japanese population. The G2385R (c.7153G>A) variant was reported as a risk factor for sporadic Parkinson disease in the Chinese population from Taiwan...

journal_title：Neuroreport

authors： Funayama M,Li Y,Tomiyama H,Yoshino H,Imamichi Y,Yamamoto M,Murata M,Toda T,Mizuno Y,Hattori N

更新日期：2007-02-12 00:00:00

abstract：:Group III metabotropic glutamate receptors (mGluR4, 6, 7, 8) are negatively coupled to adenylate cyclase and, when activated presynaptically, decrease the release of glutamate and GABA. We have used intracerebroventricular injections of agonists and antagonists believed to act selectively on these receptors to study t...

journal_title：Neuroreport

authors： Ghauri M,Chapman AG,Meldrum BS

更新日期：1996-06-17 00:00:00

abstract：:Older adults are known to gain more than younger adults from the simultaneous presentation of semantically congruent sensory stimuli. Although these findings are quite exciting, they may not solely be due to age-related differences in multisensory processing. Rather, enhanced integration may be explained by alteration...

journal_title：Neuroreport

authors： Peiffer AM,Mozolic JL,Hugenschmidt CE,Laurienti PJ

更新日期：2007-07-02 00:00:00

abstract：:Acute mitochondrial dysfunction in the cochlea is likely to result in hearing loss as a consequence of local energy shortage, similar to ischemia- or noise-induced hearing loss. To establish an animal model of acute cochlear mitochondrial dysfunction, we applied a mitochondrial toxin, 3-nitropropionic acid (3-NP) in t...

journal_title：Neuroreport

authors： Hoya N,Okamoto Y,Kamiya K,Fujii M,Matsunaga T

更新日期：2004-07-19 00:00:00

abstract：:Production and differentiation of olfactory neurons occur in spherical, multi-neuronal aggregates that form in cultures where dissociated newborn rat nasal cells are plated on to CNS glial cells. We show here that neuronal cell bodies were primarily located in the peripheral layers of the spheres, and almost every neu...

journal_title：Neuroreport

authors： Pixley SK,Bage M,Miller D,Miller ML,Shi M,Hastings L

更新日期：1994-01-31 00:00:00

abstract：:Semi-quantitative single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular tr...

journal_title：Neuroreport

authors： Tkatch T,Baranauskas G,Surmeier DJ

更新日期：1998-06-22 00:00:00

abstract：:We used whole-cell recording to identify, for the first time, GABAergic tonic current in subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of the gamma-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49 of 73 substantia gelatinosa neurons. Thes...

journal_title：Neuroreport

authors： Takahashi A,Mashimo T,Uchida I

更新日期：2006-08-21 00:00:00

abstract：:Event-related potentials were recorded in healthy volunteers to test the accuracy of the human brain to extract, preattentively, auditory abstract rules. The abstract rule was determined by the frequency relationship between two pure tones forming a pair. The standard pairs had identical tone frequency, whereas the de...

journal_title：Neuroreport

authors： Carral V,Corral MJ,Escera C

更新日期：2005-02-28 00:00:00

abstract：:To investigate the neurobiological bases of visual hallucinations in dementia with Lewy bodies (DLB), regional cerebral glucose metabolism was compared among three patient groups; DLB with visual hallucinations, DLB without visual hallucinations and Alzheimer's disease (AD) without visual hallucinations. The regional ...

journal_title：Neuroreport

authors： Imamura T,Ishii K,Hirono N,Hashimoto M,Tanimukai S,Kazuai H,Hanihara T,Sasaki M,Mori E

更新日期：1999-06-23 00:00:00

abstract：:In order to investigate GABA uptake into Müller glial cells electrophysiologically, we used the whole-cell voltage-clamp technique. Since Müller cells were insensitive to application of muscimol and baclofen, the expression of GABAA and GABAB receptors can be excluded. Therefore, the observed GABA current must be due ...

journal_title：Neuroreport

authors： Biedermann B,Eberhardt W,Reichelt W

更新日期：1994-01-12 00:00:00

abstract：:Axonal atrophy may reflect earlier and more reversible events in neurodegeneration and ageing than somatic atrophy. Innervation density by sympathetic fibres from the rat superior cervical ganglion (SCG) to the middle cerebral artery (MCA) decreases dramatically in old age, while that to the iris is largely unchanged....

journal_title：Neuroreport

authors： Kuchel GA,Poon T,Irshad K,Richard C,Julien JP,Cowen T

更新日期：1997-02-10 00:00:00

abstract：:The distribution of activated NF-kappaB (p65) was studied in granule cells of the rat fascia dentata using confocal laser scanning microscopy and preembedding immunogold electron microscopy. Activated NF-kappaB, detected with a monoclonal antibody specific for the nuclear localization signal-epitope, was found in prox...

journal_title：Neuroreport

authors： Kaltschmidt B,Deller T,Frotscher M,Kaltschmidt C

更新日期：2000-03-20 00:00:00

abstract：:This study reports on a 9-year-old girl who developed West syndrome and showed clinical features fulfilling the main revised diagnostic criteria for typical Rett syndrome (hand washing, severe cognitive impairment with absence of language, ataxic gait, progressive scoliosis and autistic features). Mutation analyses fo...

journal_title：Neuroreport

authors： Romaniello R,Saettini F,Panzeri E,Arrigoni F,Bassi MT,Borgatti R

更新日期：2015-03-25 00:00:00

abstract：:The neural origins of the cortical response to rare sensory events remain poorly understood. Using simultaneous event-related potentials and magnetic resonance imaging, we investigated the anatomical profile of regional activity at various processing stages during performance of auditory and visual variants of an oddb...

journal_title：Neuroreport

authors： Rezaie R,Simos PG,Papanicolaou AC,Castillo EM,Moser DC,Passaro AD,Fletcher JM

更新日期：2011-02-16 00:00:00

abstract：:The effects of smoking marijuana on cognition and brain function were assessed with PET using H2(15)O. Regional cerebral blood flow (rCBF) was measured in five recreational users before and after smoking a marijuana cigarette, as they repeatedly performed an auditory attention task. Blood flow increased following smok...

journal_title：Neuroreport

authors： O'Leary DS,Block RI,Flaum M,Schultz SK,Boles Ponto LL,Watkins GL,Hurtig RR,Andreasen NC,Hichwa RD

更新日期：2000-11-27 00:00:00

abstract：:Spinal cord injury (SCI) causes motor dysfunction and depression, which hinders the recovery of motor function. Body weight-supported treadmill training (BWSTT) should be considered an effective method for functional rehabilitation after SCI, as it is an efficacious intervention in healthcare with no side effects. Bec...

journal_title：Neuroreport

authors： Liu CH,Zhao BL,Li WT,Zhou XH,Jin Z,An LB

更新日期：2020-12-16 00:00:00

abstract：:In the present study, changes in the cytokine system (IL-1 beta, IL-2, IL-3, IL-6 and TNF alpha) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNF alpha, a decrease in that of IL-2 and of IL-3 with no change in IL-1 beta and in IL-6 secretion lev...

journal_title：Neuroreport

authors： Mittwoch-Jaffe T,Shalit F,Srendi B,Yehuda S

更新日期：1995-03-27 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:It is well known that dendritic cells play a key role in producing antigen-specific responses. Inversely, tolerogenic dendritic cells (TolDCs), a specialized subset, induce immune tolerance and negatively regulate autoimmune responses. Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the m...

journal_title：Neuroreport

authors： Chen Z,Yang D,Peng X,Lin J,Su Z,Li J,Zhang X,Weng Y

更新日期：2018-03-07 00:00:00