Regional and sex-dependent alterations in Purkinje cell density in the valproate mouse model of autism.

abstract：:We can report, that by the use of indirect immunofluorescence techniques, that rat spinal motoneurons contain galanin-like immunoreactivity (LI). Furthermore, that galanin and calcitonin gene-related peptide (CGRP)-LI coexist in a number of spinal motoneurons. Co-localization could be demonstrated as thoracic, lumbar ...

journal_title：Neuroreport

authors： Johnson H,Hökfelt T,Ulfhake B

更新日期：1992-04-01 00:00:00

abstract：:In the water-maze test, the linoleic acid derivative, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) (1 mg/kg, intraperitoneally), significantly shortened the prolonged latency for accelerated-senescence-prone mice 8 (SAMP8), reaching a level similar to the latency for accelerated-senescence-res...

journal_title：Neuroreport

authors： Yaguchi T,Nagata T,Mukasa T,Fujikawa H,Yamamoto H,Yamamoto S,Iso H,Tanaka A,Nishizaki T

更新日期：2006-01-23 00:00:00

abstract：:Interleukin-6 (IL-6) is a neurotrophic cytokine, however, its direct effect on nerve regeneration has not been well characterized. We therefore examined the effect of IL-6 on neurite regeneration using the rat dorsal root ganglion. IL-6 significantly enhanced neurite regeneration from transected nerve terminals. We al...

journal_title：Neuroreport

authors： Shuto T,Horie H,Hikawa N,Sango K,Tokashiki A,Murata H,Yamamoto I,Ishikawa Y

更新日期：2001-04-17 00:00:00

abstract：:One problem in motor control concerns the mechanism whereby the central nervous system translates the motor cortical command encoded in cell activity into a coordinated contraction of limb muscles to generate a desired motor output. This problem is closely related to the design of adaptive systems that transform neuro...

journal_title：Neuroreport

authors： Lukashin AV,Amirikian BR,Georgopoulos AP

更新日期：1996-11-04 00:00:00

abstract：:Adult male hamsters and rats were reared for 2 months in either an isolated condition (IC) or a social condition (SC). The lengths of synaptic active zones (SAZ) of synapses in the granule cell layer of the accessory olfactory bulb were measured as an indicator of synaptic size in perforated and non-perforated synapse...

journal_title：Neuroreport

authors： Matsuoka M,Mori Y,Ichikawa M

更新日期：1996-10-02 00:00:00

abstract：:Neuromagnetic signals evoked by synthesized syllables (/bae/ and /gae/) were recorded over the left auditory cortex of healthy humans. The fundamental frequencies of the syllables varied as if the same speaker had pronounced them at 16 different pitches. Specific mismatch responses to infrequent syllables among freque...

journal_title：Neuroreport

authors： Aulanko R,Hari R,Lounasmaa OV,Näätänen R,Sams M

更新日期：1993-09-30 00:00:00

abstract：:Secondary brain injury imposes great effects on the prognosis of patients following traumatic brain injury (TBI). Accumulating evidence suggests that nuclear factor erythroid 2-related factor 2 (Nrf2) could play a neuroprotective role in experimental TBI models by regulating the expression of numerous antioxidant, ant...

journal_title：Neuroreport

authors： He Y,Yan H,Ni H,Liang W,Jin W

更新日期：2019-03-20 00:00:00

abstract：:Epidemiological data show correlations between hypercholesterolemia and Alzheimer's disease (AD). We test the hypothesis that hypercholesterolemia modulates Abeta deposition in mice overexpressing the human APP695 Swedish mutation (K670N and M671L) (TgAPPsw). Feeding mice a high fat/high cholesterol (HFHC) diet for 7-...

journal_title：Neuroreport

authors： Shie FS,Jin LW,Cook DG,Leverenz JB,LeBoeuf RC

更新日期：2002-03-25 00:00:00

abstract：:Limbic event-related potentials related to verbal but not to visual recognition memory have been found to be attenuated within the epileptic hippocampus of patients with temporal lobe epilepsy (TLE). To identify hippocampal contributions to visual processing and memory we recorded intracranial ERPs directly from withi...

journal_title：Neuroreport

authors： Vannucci M,Dietl T,Pezer N,Viggiano MP,Helmstaedter C,Schaller C,Elger CE,Grunwald T

更新日期：2003-08-06 00:00:00

abstract：:The aim of this investigation was to study whether melatonin affects the release of oxytocin and vasopressin by the pituitary neurointermediate lobe of the Syrian hamster in vitro. The effect of melatonin was studied on the unstimulated (pre- and post-K+ -stimulated) release of oxytocin and vasopressin and on the resp...

journal_title：Neuroreport

authors： Juszczak M,Debeljuk L,Bartke A,Stempniak B

更新日期：1995-12-15 00:00:00

abstract：:Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...

journal_title：Neuroreport

authors： Yuan J,Young BJ,Martinus RD

更新日期：2006-02-27 00:00:00

abstract：:Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-deliv...

journal_title：Neuroreport

authors： Ichihara-Takeda S,Takeda K,Funahashi S

更新日期：2010-03-31 00:00:00

abstract：:Wilson's disease (WD) is an autosomal recessive inheritance disorder of copper metabolism due to mutations in the ATP7B gene. The distribution of ATP7B gene mutations is diverse in different population. This study aimed to examine the genotypes of the ATP7B mutant alleles in WD patients from Southern China. Genomic DN...

journal_title：Neuroreport

authors： Wei Z,Huang Y,Liu A,Diao S,Yu Q,Peng Z,Hong M

更新日期：2014-10-01 00:00:00

abstract：:Transplanted olfactory ensheathing cells (OECs) have previously been demonstrated to support axonal growth and myelination in the adult rat CNS. Here, the capacity of donor OECs to control the direction of axonal regeneration has been investigated following transplantation, as elongated columns, into the thalamus of a...

journal_title：Neuroreport

authors： Pérez-Bouza A,Wigley CB,Nacimiento W,Noth J,Brook GA

更新日期：1998-09-14 00:00:00

abstract：:This study investigated whether mild birth complications (C-section birth, C-section + 15 min global anoxia) interact with stress at adulthood to modulate levels of [3H]WIN 35428 binding to dopamine transporters (DAT) in rat brain. Without stress, adult C-sectioned rats showed increased DAT binding in the dorsal stria...

journal_title：Neuroreport

authors： El-Khodor BF,Boksa P

更新日期：2002-02-11 00:00:00

abstract：:This study was designed to investigate the expression of transient receptor potential melastatin 3 (TRPM3) and transient receptor potential vanilloid type 4 (TRPV4) in the trigeminal spinal subnucleus caudalis of a rat model of trigeminal neuralgia (TN). The influence of botulinum toxin type A (BTX-A) on the expressio...

journal_title：Neuroreport

authors： Zhang Y,Su Q,Lian Y,Chen Y

更新日期：2019-07-03 00:00:00

abstract：:As manifestations of prion diseases include disturbances of hypothalamic and pituitary functions, we tested the hypothesis that the cellular prion protein (PrPC) has a role as modulator of the hypothalamic-pituitary-adrenal axis. The level of corticosterone and adrenocorticotropic hormone were compared in PrPC null (P...

journal_title：Neuroreport

authors： Sanchez-Alavez M,Criado JR,Klein I,Moroncini G,Conti B

更新日期：2008-10-08 00:00:00

abstract：:Human scalp EEG has demonstrated that global coherence among distant areas increases during cognitive tasks, suggesting that oscillating neural activities work to generate global neuronal assemblies for cognitive functions. The theta oscillation in a frequency range of 4-8 Hz with large amplitudes which emerges during...

journal_title：Neuroreport

authors： Mizuhara H,Wang LQ,Kobayashi K,Yamaguchi Y

更新日期：2004-06-07 00:00:00

abstract：:In the current study we explored the relationship between neurometabolites measured by proton magnetic resonance spectroscopy (1H-MRS) and cognitive ability assessed with a battery of neuropsychological tests. Forty-five participants were recruited from the local college community, and examined utilizing neuropsycholo...

journal_title：Neuroreport

authors： Jung RE,Yeo RA,Chiulli SJ,Sibbitt WL Jr,Weers DC,Hart BL,Brooks WM

更新日期：1999-11-08 00:00:00

abstract：:The mixed-action κ-opioid receptor (KOR) agonist, pentazocine, binds to both KOR and the µ-opioid receptor (MOR). Racemic (±)-pentazocine and (-)-pentazocine, each administered systemically, have been shown to produce antinociception in various animal models. In contrast, racemic (±)-pentazocine failed to produce anti...

journal_title：Neuroreport

authors： Robinson DL Jr,Nag S,Mokha SS

更新日期：2018-07-04 00:00:00

abstract：:Internet gaming disorder is defined as excessive and compulsive use of the internet to engage in games that leads to clinically significant psychosocial impairment. We tested the hypothesis that individuals with internet gaming disorder would be less sensitive to high-risk situations and show aberrant brain activation...

journal_title：Neuroreport

authors： Lee D,Lee J,Yoon KJ,Kee N,Jung YC

更新日期：2016-05-25 00:00:00

abstract：:Pulmonary slowly adapting receptors (SARs) and rapidly adapting receptors (RARs) are important components of various respiratory reflexes. In anesthetized, paralyzed and artificially ventilated rats, we found an inhibitory linkage from the former to the latter system at the level of their second-order relay neurons (P...

journal_title：Neuroreport

authors： Ezure K,Tanaka I

更新日期：2000-06-05 00:00:00

abstract：:Intracerebral or intraspinal grafting of genetically modified primary fibroblasts has been shown to enhance functional recovery in several models of CNS disease, including spinal cord injury. Most of these studies utilized retrovirus vectors. In this report, we describe in vitro conditions for genetically modifying pr...

journal_title：Neuroreport

authors： Liu Y,Himes BT,Tryon B,Moul J,Chow SY,Jin H,Murray M,Tessler A,Fischer I

更新日期：1998-04-20 00:00:00

abstract：:Cell death and neurofibrillary tangle formation are prominent features of Alzheimer's disease (AD). It has been suggested that DNA damage may reflect neuronal vulnerability. In this context, the Ced homologue Bcl-2 is able to repress a number of cell death programs. Recently we found both numerous nuclei exhibiting DN...

journal_title：Neuroreport

authors： Su JH,Satou T,Anderson AJ,Cotman CW

更新日期：1996-01-31 00:00:00

abstract：:To investigate the implications of duration of deafness in the rehabilitation of unilateral deafness utilizing cochlear implantation. From the ongoing prospective cochlear implantation in unilateral deafness study, we looked at five adults who received a cochlear implant for long-term unilateral deafness. Speech perce...

journal_title：Neuroreport

authors： Távora-Vieira D,Boisvert I,McMahon CM,Maric V,Rajan GP

更新日期：2013-09-11 00:00:00

abstract：:Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...

journal_title：Neuroreport

authors： Orr-Urtreger A,Kedmi M,Rosner S,Karmeli F,Rachmilewitz D

更新日期：2005-07-13 00:00:00

abstract：:We investigated whether cerebellar transcranial magnetic stimulation (C-TMS) facilitates the excitability of the ipsilateral soleus motoneuron pool in resting humans, and whether the facilitation is modulated by a task that promotes cerebellar activity. A test tibial nerve stimulus evoking the H-reflex from the right ...

journal_title：Neuroreport

authors： Matsugi A,Mori N,Uehara S,Kamata N,Oku K,Mukai K,Nagano K

更新日期：2014-12-03 00:00:00

abstract：:We investigated the effect of nicotine, a nicotinic agonist, and D-cycloserine (DCS, a partial glycine-B agonist of the N-methyl-D-aspartate (NMDA) receptor complex) on aging-induced defects of water maze (WM) spatial navigation in rats. Nicotine (0.3 mg kg-1, s.c.) or DCS (10 mg kg-1, i.p.) enhanced acquisition of th...

journal_title：Neuroreport

authors： Riekkinen M,Riekkinen P Jr

更新日期：1997-02-10 00:00:00

abstract：:The environment in which cocaine is experienced becomes associated with the effects of the drug and can then elicit cocaine craving. This study examined whether the hippocampus is involved in such associations using the conditioned place preference model. Rats received bilateral lesions of the dorsal or ventral hippoc...

journal_title：Neuroreport

authors： Meyers RA,Zavala AR,Neisewander JL

更新日期：2003-11-14 00:00:00

abstract：:Retrograde transneuronal viral labelling and immunocytochemical methods were used for revealing neuronal networks controlling the left ventricle myocardium of the rat heart. After injections of 1 microliter pseudorabies virus solution (3 x 10(6) PFU ml-1) into the left ventricle, infected orthosympathetic preganglioni...

journal_title：Neuroreport

authors： Ter Horst GJ,Van den Brink A,Homminga SA,Hautvast RW,Rakhorst G,Mettenleiter TC,De Jongste MJ,Lie KI,Korf J

更新日期：1993-09-30 00:00:00