Enhanced phosphorylation of S6 protein in mouse cortical layer V and subplate neurons.

abstract：:Clozapine is an effective atypical antipsychotic that has high affinity for serotonin type 6 receptors (5HT6). We tested the hypothesis that clinical response to clozapine in patients refractory to typical antipsychotic treatment is related to the genetic variant (C267T) of the 5HT6 receptors. Ninety-nine schizophreni...

journal_title：Neuroreport

authors： Yu YW,Tsai SJ,Lin CH,Hsu CP,Yang KH,Hong CJ

更新日期：1999-04-26 00:00:00

abstract：:It is unclear whether the neural algorithm that underlies stereoscopic vision in birds incorporates both low level (camouflage breaking) and high level (depth ordering) comparisons of information available to each of the eyes. Both visual functions were successfully tested by examining transitive inference performance...

journal_title：Neuroreport

authors： van der Willigen RF,Frost BJ,Wagner H

更新日期：1998-04-20 00:00:00

abstract：:Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation of BMMCs is considered a potential approach to promoting the repair of ischemic damaged organs. H...

journal_title：Neuroreport

authors： Takagi T,Yoshida T,Okada M,Hata R,Hato N,Gyo K,Hakuba N

更新日期：2014-08-06 00:00:00

abstract：:For many diseases and injuries of the central nervous system, transplantation of neural progenitor cells is being evaluated as a possible treatment option. Although local, intravenous and subarachnoid injections have been reported as administration methods of neural progenitor cells, each of these methods has limitati...

journal_title：Neuroreport

authors： Hamasaki T,Tanaka N,Ishida O,Yanada S,Kamei N,Fujiwara Y,Nishida K,Nakanishi K,Sharman P,Kawamata S,Ochi M

更新日期：2005-10-17 00:00:00

abstract：:Alzheimer disease (AD) patients show increased plasma levels of homocysteine, whose conversion to methionine is catalyzed by methionine synthase (MS). Although altered MS activity may result from the MS A2756G polymorphism, the latter's possible associ-ation with AD remains unexplored. To assess whether the MS A2756G ...

journal_title：Neuroreport

authors： Beyer K,Lao JI,Latorre P,Riutort N,Matute B,Fernández-Figueras MT,Mate JL,Ariza A

更新日期：2003-07-18 00:00:00

abstract：:Mental rotation performance has been found to produce one of the largest sex differences in cognition. Many theories suggest that this effect should be accompanied by a sex difference in functional cerebral asymmetry, but empirical data are more than equivocal probably because of (a) the use of inappropriate stimuli a...

journal_title：Neuroreport

authors： Pellkofer J,Jansen P,Heil M

更新日期：2014-08-06 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis...

journal_title：Neuroreport

authors： Hadjikhani N,Chabris CF,Joseph RM,Clark J,McGrath L,Aharon I,Feczko E,Tager-Flusberg H,Harris GJ

更新日期：2004-02-09 00:00:00

abstract：:This study examined the effects of cocaine HCl and ambient temperature on the core body temperature of the rat. To further examine the mechanisms of cocaine-induced changes in temperature regulation, the effects of cocaine on behavioral thermoregulatory responses were also observed. At normal room temperature (20 degr...

journal_title：Neuroreport

authors： Gonzalez LP

更新日期：1993-01-01 00:00:00

abstract：:Muller glial cells of the sensory retina mediate K+ and water fluxes that are facilitated by aquaporin-4 (AQP4) water channels and by Kir4.1-K+ channels. However, it is not known which subtypes of aquaporins are expressed in the mammalian retina. Using RT-PCR, we found that both human and rat retinas express mRNA for ...

journal_title：Neuroreport

authors： Tenckhoff S,Hollborn M,Kohen L,Wolf S,Wiedemann P,Bringmann A

更新日期：2005-01-19 00:00:00

abstract：:Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg mo...

journal_title：Neuroreport

authors： Sharpe LG,Jaffe JH

更新日期：1990-09-01 00:00:00

abstract：:Widespread invasiveness, represented by the invasion and migration, is the most important characteristic of glioblastoma multiforme (GBM) and is the main reason for therapeutic failure and recurrence of the tumor. Hypoxia is one of the main microenvironment in determining tumor invasiveness. Therefore, intense efforts...

journal_title：Neuroreport

authors： Huang W,Ding X,Ye H,Wang J,Shao J,Huang T

更新日期：2018-12-12 00:00:00

abstract：:Diabetic peripheral neuropathy is the most common complication of diabetes mellitus and leads to sensory symptoms, including diabetic neuropathic pain (DNP). DNP is a major public health problem because it has a considerable impact on life quality of diabetes mellitus patients. Therefore, development of novel effectiv...

journal_title：Neuroreport

authors： Li P,Xiong DL,Sun WP,Xu SY

更新日期：2018-12-05 00:00:00

abstract：:In order to clarify whether neurophysiological profiles affect the performance of brain machine interfaces (BMI), we examined the relationships between amplitudes of movement-related cortical fields (MRCFs) and decoding performances during movement. Neuromagnetic activities were recorded in nine healthy participants d...

journal_title：Neuroreport

authors： Sugata H,Goto T,Hirata M,Yanagisawa T,Shayne M,Matsushita K,Yoshimine T,Yorifuji S

更新日期：2012-01-04 00:00:00

abstract：:The ATP-gated cation channel P2X3 is expressed selectively by rat sensory neurones, and may play a role in nociception by binding ATP released from damaged or inflamed tissues. However, the distribution of this channel in human sensory neurons is not known. Using a specific antibody, we have demonstrated intense P2X3 ...

journal_title：Neuroreport

authors： Yiangou Y,Facer P,Birch R,Sangameswaran L,Eglen R,Anand P

更新日期：2000-04-07 00:00:00

abstract：:It has been reported that neurons in the amygdala respond to visual cues that predict reward and aversive outcomes. However, it remains unclear whether the representation of reinforcement in the amygdala depends on the relative preference for an outcome compared with another simultaneously available outcome. In this s...

journal_title：Neuroreport

authors： Hirai D,Hosokawa T,Inoue M,Miyachi S,Mikami A

更新日期：2009-04-22 00:00:00

abstract：:In mammals, the thalamic intergeniculate leaflet (IGL) conveys behavioral (non-photic) phase-resetting information to the circadian clock of the suprachiasmatic nucleus. Here we report a 24 h fluctuation in in vivo serotonin release in the hamster IGL region, peaking at night. Novel wheel exposure at midday, a stimulu...

journal_title：Neuroreport

authors： Grossman GH,Farnbauch L,Glass JD

更新日期：2004-01-19 00:00:00

abstract：:We examined the induction of progesterone receptor-immunoreactive (PR-ir) cells by estrogen in the rat preoptic area and ventromedial hypothalamic nucleus. Ovariectomized young (3-month-old) and old (24-month-old) female rats were treated with estrogen or cholesterol for 4 days. Estrogen significantly increased PR-ir ...

journal_title：Neuroreport

authors： Furuta M,Fukushima A,Chiba S,Sano A,Akema T,Kimura F,Funabashi T

更新日期：2010-08-04 00:00:00

abstract：:Extrasynaptic transmission is mediated by the diffusion of transmitters, through the extracellular space (ECS) to receptors on neurons and glia. The three-dimensional diffusion of tetramethylammonium (mol. wt 74.1 kDa) was investigated in the isolated rat spinal cord at postnatal days 4-20. The diffusion parameters of...

journal_title：Neuroreport

authors： Prokopová S,Vargová L,Syková E

更新日期：1997-11-10 00:00:00

abstract：:Statistical analysis on diffusion tensor imaging has been used extensively in mesial temporal lobe epilepsy (mTLE) and most studies report decrease in fractional anisotropy (FA) in multiple white matter regions. However, these findings vary across studies and between regions. Therefore, in this study, we used tract-ba...

journal_title：Neuroreport

authors： An J,Fang P,Wang W,Liu Z,Hu D,Qiu S

更新日期：2014-07-09 00:00:00

abstract：:Two voltage-activated Na+ channel blockers, lamotrigine and flunarizine were applied ionophoretically to extracellularly recorded dorsal horn neurones to assess effects on activation by noxious (mustard oil) and innocuous (brush) stimuli. Lamotrigine and flunarizine caused significantly greater reductions in mustard o...

journal_title：Neuroreport

authors： Blackburn-Munro G,Fleetwood-Walker SM

更新日期：1997-05-06 00:00:00

abstract：:Magnetic brain responses were recorded to clarify the cortical representation of vowel processing in Japanese. We investigated the peak latencies and equivalent current dipoles of the auditory N1m responses to the Japanese vowels [a], [i], [o], and [u]. In intraindividual analyses for a single participant, well-replic...

journal_title：Neuroreport

authors： Ogata E,Yumoto M,Itoh K,Sekimoto S,Karino S,Kaga K

更新日期：2006-07-31 00:00:00

abstract：:Groups of 20 C57BL/6J mice (10 males and 10 females) were given BSE strain 301C i.p. and subsequently given 2 microg recombinant human TGFbeta1 s.c. at single or multiple times. There was a significant positive correlation between the day of TGFbeta1 administration and incubation time; the later TGFbeta1 was administe...

journal_title：Neuroreport

authors： Kempster S,Collins ME,Edington N

更新日期：2004-10-05 00:00:00

abstract：:Direct application of brain-derived neurotrophic factor (BDNF) to the cut end of axotomized immature motor neurones had only transient survival-promoting effects. Therefore, we have examined whether additional delivery of BDNF with repeated subcutaneous injections (1 mg/ml) could potentiate this short-term rescue of t...

journal_title：Neuroreport

authors： Vejsada R,Sagot Y,Kato AC

更新日期：1994-10-03 00:00:00

abstract：:Cortical processes underlying perception of musical consonance were investigated by long-latency auditory evoked potentials (EPs). Subjects listened to a random sequence of dyadic pure tones paired at various pitch intervals (1, 4, 6, 7, or 9 semitones). Amplitudes of P2 and N2 components of auditory EPs were signific...

journal_title：Neuroreport

authors： Itoh K,Suwazono S,Nakada T

更新日期：2003-12-19 00:00:00

abstract：:N-CAM-deficient mice display anatomical and electrophysiological abnormalities in the CNS and behavioral deficits. Here, we address the question whether information processing is altered in these mice by analysis of the expression of c-fos and arg 3.1/arc in N-CAM-deficient mice after presentation of saccharin as nove...

journal_title：Neuroreport

authors： Montag-Sallaz M,Montag D,Schachner M

更新日期：2003-07-18 00:00:00

abstract：:Axotomy-induced death of corticospinal neurons (CSN) is prevented by intracotrical infusions of BDNF or NT-3 within the first week after axotomy. The present study examined whether this represents merely a delay of CSN death or whether BDNF and NT-3 can promote long-term survival of these neurons in vivo. The neurotro...

journal_title：Neuroreport

authors： Hammond EN,Tetzlaff W,Mestres P,Giehl KM

更新日期：1999-08-20 00:00:00

abstract：:The present study aims to study sequential alterations occurring in both dopaminergic neurons and microglia in substantia nigra (SN) following intrastriatal injection of 1-methyl-4-phenylpridium ion (MPP+) in rats. Heme oxygenase-1 (HO-1), a marker of oxidative stress, first appeared in dopaminergic neurons in SN at 1...

journal_title：Neuroreport

authors： Miwa H,Kubo T,Morita S,Nakanishi I,Kondo T

更新日期：2004-04-29 00:00:00

abstract：:Retrograde transneuronal viral labelling and immunocytochemical methods were used for revealing neuronal networks controlling the left ventricle myocardium of the rat heart. After injections of 1 microliter pseudorabies virus solution (3 x 10(6) PFU ml-1) into the left ventricle, infected orthosympathetic preganglioni...

journal_title：Neuroreport

authors： Ter Horst GJ,Van den Brink A,Homminga SA,Hautvast RW,Rakhorst G,Mettenleiter TC,De Jongste MJ,Lie KI,Korf J

更新日期：1993-09-30 00:00:00

abstract：:To test the possible role of ATP in transducing or modulating touch sensation, an isolated skin-nerve preparation from the toad, Bufo marinus, perfused on the inner side, was used to examine the effects of ATP on slowly adapting (SA) and rapidly adapting (RA) mechanoreceptors, identified by ramp and hold indentation o...

journal_title：Neuroreport

authors： Fallon JB,Maroto R,Hamill OP,Proske U

更新日期：2002-08-07 00:00:00

abstract：:A tritiated specific and highly potent 5-HT4 antagonist: [3H]-GR113808 was used to label specific binding sites in human brain and for comparison in guinea-pig brain. [3H]-GR113808 association and dissociation were rapid, the binding was saturable and displaced by various serotoninergic agents with an affinity corresp...

journal_title：Neuroreport

authors： Waeber C,Sebben M,Grossman C,Javoy-Agid F,Bockaert J,Dumuis A

更新日期：1993-09-10 00:00:00