解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric effects. Δ(9)-Tetrahydrocannabivarin (THCV) is a neutral CB1 antagonist producing hypophagia and body weight reduction in lean mice. We investigated its effects in die...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2013.9
更新日期:2013-05-27 00:00:00
abstract:BACKGROUND:Individuals who focused on calorie counting lost more weight than those who focused on increasing vegetable and fruit (V&F) intake in a weight loss program. We now present serum carotenoid data (biomarkers of V&F intake) from both groups and test whether these biomarkers correlate with changes in weight and ...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2012.22
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND AND DESIGN:Adiponectin is an adipokine secreted primarily from adipose tissue that can influence circulating plasma glucose and lipid levels through multiple mechanisms involving a variety of organs. In humans, reduced plasma adiponectin levels induced by obesity are associated with insulin resistance and ty...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2012.18
更新日期:2012-09-10 00:00:00
abstract::Obesity and related complications are major health burdens. Almost 700 million adults are currently obese globally and the prevalence is predicted to rise towards 2030. The sudden change of lifestyle with physical inactivity and excessive calorie intake undoubtedly have a major part of the epidemic development; howeve...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2012.9
更新日期:2012-07-30 00:00:00
abstract::Human obesity has evolved into a global epidemic. Interestingly, a similar trend has been observed in many animal species, although diet composition, food availability and physical activity have essentially remained unchanged. This suggests a common factor-potentially an environmental factor affecting all species. Coi...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2012.2
更新日期:2012-03-05 00:00:00
abstract:OBJECTIVE:To examine the social and behavioural correlates of metabolic phenotypes during 'at-risk' and 'case' stages of the metabolic disease continuum. DESIGN:Cross-sectional study of a random population sample. PARTICIPANTS:A total of 718 community-dwelling adults (57% female), aged 18-92 years from a regional Sou...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2011.20
更新日期:2012-01-16 00:00:00
abstract:OBJECTIVE:Along with the increasing prevalence of obesity and related diseases, particularly atherosclerotic diseases, metabolic syndrome (MetS) is now a common and major public health issue in many countries around the world. Adiponectin, a protein secreted by the adipose tissue, has become recognized as a key player ...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2011.13
更新日期:2011-10-10 00:00:00
abstract:OBJECTIVE:Microfibrillar-associated protein 5 (MFAP5) is an extracellular matrix (ECM) glycoprotein, which is colocalized with microfibrils in elastin networks. Its function in adipose tissue (AT) is not known. We have recently shown that the expression of MFAP5 is downregulated in AT along with weight reduction (WR) i...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2011.10
更新日期:2011-08-29 00:00:00
abstract:OBJECTIVE:The gut microbiota contribute otherwise impossible metabolic functions to the human host. Shifts in the relative proportions of gut microbial communities in adults have been correlated with intestinal disease and have been associated with obesity. The aim of this study was to elucidate differences in gut micr...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2011.8
更新日期:2011-07-18 00:00:00
abstract:OBJECTIVE:Statin therapy reduces coronary heart disease (CHD) and mortality in individuals with elevated C-reactive protein (CRP) but low-density lipoprotein cholesterol below the threshold at which statin therapy is recommended. We determined the proportion of individuals with elevated CRP in whom statin therapy was n...
journal_title:Nutrition & diabetes
pub_type: 杂志文章
doi:10.1038/nutd.2011.4
更新日期:2011-05-23 00:00:00