Beyond the fourth wave of genome-wide obesity association studies.

abstract：BACKGROUND/OBJECTIVES:Neuroimaging studies in obese subjects have identified abnormal activation of key regions of central reward circuits, including the nucleus accumbens (NAcc), in response to food-related stimuli. We aimed to examine whether women with elevated body mass index (BMI) show structural and resting state...

journal_title：Nutrition & diabetes

authors： Coveleskie K,Gupta A,Kilpatrick LA,Mayer ED,Ashe-McNalley C,Stains J,Labus JS,Mayer EA

更新日期：2015-01-19 00:00:00

abstract：:Following publication, the authors asked to add the following institution to the affiliations of author Madoka Matsushita: Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine Both the PDF and HTML versions of the Article have been updated accordingly. ...

journal_title：Nutrition & diabetes

authors： Matsushita M,Muramoto A,Nomura E,Eguchi Y,Kato A,Sano Y,Kabayama M,Arakawa M,Oguma Y,Yabe D,Matsunaga M,Yatsuya H,Arima H,Tsushita K

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse psychiatric effects. Δ(9)-Tetrahydrocannabivarin (THCV) is a neutral CB1 antagonist producing hypophagia and body weight reduction in lean mice. We investigated its effects in die...

journal_title：Nutrition & diabetes

authors： Wargent ET,Zaibi MS,Silvestri C,Hislop DC,Stocker CJ,Stott CG,Guy GW,Duncan M,Di Marzo V,Cawthorne MA

更新日期：2013-05-27 00:00:00

abstract：AIM:The purpose of this study was to investigate the association of dietary patterns with the risk of insulin resistance (IR), diabetes mellitus (DM), and central obesity in China. METHODS:We performed a cross-sectional study on 1432 participants, aged 40-65 years in Hangzhou, Zhejiang province, China. Dietary intake ...

journal_title：Nutrition & diabetes

authors： Yin X,Chen Y,Lu W,Jin T,Li L

更新日期：2020-06-04 00:00:00

abstract：OBJECTIVE:Endocannabinoids and neuropeptide Y (NPY) promote energy storage via central and peripheral mechanisms. In the hypothalamus, the two systems were suggested to interact. To investigate such interplay also in non-hypothalamic tissues, we evaluated endocannabinoid levels in obese OE-NPY(DβH) mice, which overexpr...

journal_title：Nutrition & diabetes

authors： Vähätalo LH,Ruohonen ST,Mäkelä S,Ailanen L,Penttinen AM,Stormi T,Kauko T,Piscitelli F,Silvestri C,Savontaus E,Di Marzo V

更新日期：2015-04-27 00:00:00

abstract：OBJECTIVE:Obesity in the United States is highly prevalent, approaching 60% for black women. We investigated whether nutrition education sessions at the work place added to internet-based wellness information and exercise resources would facilitate weight and fat mass loss in a racially diverse population of overweight...

journal_title：Nutrition & diabetes

authors： Carnie A,Lin J,Aicher B,Leon B,Courville AB,Sebring NG,de Jesus J,Dellavalle DM,Fitzpatrick BD,Zalos G,Powell-Wiley TM,Chen KY,Cannon RO 3rd

更新日期：2013-12-23 00:00:00

abstract：OBJECTIVE:In recent years, people have changed their eating habits, and high-fructose-containing bubble tea has become very popular. High-fructose intake has been suggested to be a key factor that induces non-alcoholic fatty liver disease (NAFLD). Kefir, a fermented milk product composed of microbial symbionts, has dem...

journal_title：Nutrition & diabetes

authors： Chen HL,Tsai TC,Tsai YC,Liao JW,Yen CC,Chen CM

更新日期：2016-12-12 00:00:00

abstract：OBJECTIVE:Microfibrillar-associated protein 5 (MFAP5) is an extracellular matrix (ECM) glycoprotein, which is colocalized with microfibrils in elastin networks. Its function in adipose tissue (AT) is not known. We have recently shown that the expression of MFAP5 is downregulated in AT along with weight reduction (WR) i...

journal_title：Nutrition & diabetes

authors： Vaittinen M,Kolehmainen M,Schwab U,Uusitupa M,Pulkkinen L

更新日期：2011-08-29 00:00:00

abstract：BACKGROUND:The role of resistant starch (RS) in glucose, insulin, insulin resistance or sensitivity, and lipid parameters have been reported in several studies and remained controversial. A pooled analysis which assessed these parameters has not been performed. Thus, we conducted a meta-analysis to sum up existing evid...

journal_title：Nutrition & diabetes

authors： Wang Y,Chen J,Song YH,Zhao R,Xia L,Chen Y,Cui YP,Rao ZY,Zhou Y,Zhuang W,Wu XT

更新日期：2019-06-05 00:00:00

abstract：:Obesity is associated with inflammatory macrophages in insulin responsive tissues and the resulting inflammatory response is a major contributor to insulin resistance. In insulin-producing pancreatic islets, the intra-islet accumulation of macrophages is observed in patients of type 2 diabetes (T2D), but such has not ...

journal_title：Nutrition & diabetes

authors： He W,Yuan T,Maedler K

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND/OBJECTIVES:Diet-induced obese (DIO) rats have altered stress (HPA) axis activity compared to diet-resistant (DR) rats when chronically exposed to a high-fat (HF) diet. Since stress axis is tightly regulated by leptin, an adipocyte-secreted hormone that is important for controlling body weight, we hypothesize...

journal_title：Nutrition & diabetes

authors： Shin AC,MohanKumar SMJ,Balasubramanian P,Sirivelu MP,Linning K,Woolcock A,James M,MohanKumar PS

更新日期：2019-03-18 00:00:00

abstract：:Coffee consumption has been reported to reduce the risk of type 2 diabetes in experimental and epidemiological studies. This anti-diabetic effect of coffee may be attributed to its high content in polyphenols especially caffeic acid and chlorogenic acid. However, the association between plasma coffee polyphenols and d...

journal_title：Nutrition & diabetes

authors： Lee AH,Tan L',Hiramatsu N,Ishisaka A,Alfonso H,Tanaka A,Uemura N,Fujiwara Y,Takechi R

更新日期：2016-06-06 00:00:00

abstract：OBJECTIVE:Statin therapy reduces coronary heart disease (CHD) and mortality in individuals with elevated C-reactive protein (CRP) but low-density lipoprotein cholesterol below the threshold at which statin therapy is recommended. We determined the proportion of individuals with elevated CRP in whom statin therapy was n...

journal_title：Nutrition & diabetes

authors： Khoo CM,Tan M,Wu Y,Wai CH,Subramaniam T,Lee J,Tai ES

更新日期：2011-05-23 00:00:00

abstract：OBJECTIVES:Obesity is associated with hyperactivation of the reward system for high-calorie (HC) versus low-calorie (LC) food cues, which encourages unhealthy food selection and overeating. However, the extent to which this hyperactivation can be reversed is uncertain, and to date there has been no demonstration of cha...

journal_title：Nutrition & diabetes

authors： Deckersbach T,Das SK,Urban LE,Salinardi T,Batra P,Rodman AM,Arulpragasam AR,Dougherty DD,Roberts SB

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Sleep duration influences weight change in children and young adults, but there is less evidence in middle-aged, and, in particular, older adults. We assessed associations between sleep duration, daytime napping and sleep disturbances, respectively, with change of weight and waist circumference in...

journal_title：Nutrition & diabetes

authors： Kowall B,Lehnich AT,Erbel R,Moebus S,Jöckel KH,Stang A

更新日期：2016-08-15 00:00:00

abstract：:Diabetes mellitus has been associated with impaired cognitive performance, particularly in verbal memory. Mediterranean diets (MedD) may lead to improvements in overall and single cognitive functions. We hypothesised that adherence to MedD associates with better performance in verbal memory in patients with type 1 or ...

journal_title：Nutrition & diabetes

authors： Kössler T,Weber KS,Wölwer W,Hoyer A,Strassburger K,Burkart V,Szendroedi J,Roden M,Müssig K,GDS Group.

更新日期：2020-04-01 00:00:00

abstract：BACKGROUNDS:Mitochondria plays a critical role in the development and pathogenesis of nonalcoholic fatty liver disease (NAFLD). Neohesperidin (NHP) could lower blood glucose and prevent obesity in mice. However, the direct effect of NHP on hepatic steatosis has not been reported. METHODS:Mice were fed with either a ch...

journal_title：Nutrition & diabetes

authors： Wang SW,Sheng H,Bai YF,Weng YY,Fan XY,Lou LJ,Zhang F

更新日期：2020-08-05 00:00:00

abstract：OBJECTIVE:The aim of dietary modification, as a cornerstone of type 2 diabetes (T2DM) management, is to optimise metabolic control and overall health. This study describes food and nutrient intake in a sample of adults with T2DM, and compares this to recommendations, and to intake in age, sex, body mass index (BMI) and...

journal_title：Nutrition & diabetes

authors： Breen C,Ryan M,McNulty B,Gibney MJ,Canavan R,O'Shea D

更新日期：2014-02-03 00:00:00

abstract：BACKGROUND:Individuals who focused on calorie counting lost more weight than those who focused on increasing vegetable and fruit (V&F) intake in a weight loss program. We now present serum carotenoid data (biomarkers of V&F intake) from both groups and test whether these biomarkers correlate with changes in weight and ...

journal_title：Nutrition & diabetes

authors： Whigham LD,Valentine AR,Johnson LK,Zhang Z,Atkinson RL,Tanumihardjo SA

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:A Mediterranean-style eating pattern is consistently associated with a decreased diabetes risk in Mediterranean and European populations. However, results in U.S. populations are inconsistent. The objective of this study was to assess whether a Mediterranean-style eating pattern would be associated with diab...

journal_title：Nutrition & diabetes

authors： O'Connor LE,Hu EA,Steffen LM,Selvin E,Rebholz CM

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND AND DESIGN:Adiponectin is an adipokine secreted primarily from adipose tissue that can influence circulating plasma glucose and lipid levels through multiple mechanisms involving a variety of organs. In humans, reduced plasma adiponectin levels induced by obesity are associated with insulin resistance and ty...

journal_title：Nutrition & diabetes

authors： Kandasamy AD,Sung MM,Boisvenue JJ,Barr AJ,Dyck JR

更新日期：2012-09-10 00:00:00

abstract：OBJECTIVE:Along with the increasing prevalence of obesity and related diseases, particularly atherosclerotic diseases, metabolic syndrome (MetS) is now a common and major public health issue in many countries around the world. Adiponectin, a protein secreted by the adipose tissue, has become recognized as a key player ...

journal_title：Nutrition & diabetes

authors： Baden MY,Yamada Y,Obata Y,Hosakawa Y,Saisho K,Tamba S,Yamamoto K,Umeda M,Furubayashi A,Tsukamoto Y,Matsuzawa Y

更新日期：2011-10-10 00:00:00

abstract：BACKGROUND/OBJECTIVES:High dietary fibre intakes may protect against obesity by influencing colonic fermentation and the colonic microbiota. Though, recent studies suggest that increased colonic fermentation contributes to adiposity. Diet influences the composition of the gut microbiota. Previous research has not evalu...

journal_title：Nutrition & diabetes

authors： Fernandes J,Su W,Rahat-Rozenbloom S,Wolever TM,Comelli EM

更新日期：2014-06-30 00:00:00

abstract：BACKGROUND/OBJECTIVES:The current obesity epidemic has spurred exploration of the developmental origin of adult heath and disease. A mother's dietary choices and health can affect both the early wellbeing and lifelong disease-risk of the offspring. SUBJECTS/METHODS:To determine if changes in the mother's diet and adip...

journal_title：Nutrition & diabetes

authors： Monks J,Orlicky DJ,Stefanski AL,Libby AE,Bales ES,Rudolph MC,Johnson GC,Sherk VD,Jackman MR,Williamson K,Carlson NE,MacLean PS,McManaman JL

更新日期：2018-04-25 00:00:00

abstract：:For convenience, health practitioners and clinicians are inclined to classify people/patients as overweight or obese based on body mass index (BMI) cutoff points of 25 and 30 kg m(-2) respectively, irrespective of age and gender. The purpose of the current study was to identity whether, for the same levels of adiposit...

journal_title：Nutrition & diabetes

authors： Nevill AM,Metsios GS

更新日期：2015-11-30 00:00:00

abstract：BACKGROUND:Model animals are valuable resources for dissecting basic aspects of the regulation of obesity and metabolism. The translatability of results relies on understanding comparative aspects of molecular pathophysiology. Several studies have shown that despite the presence of overt obesity and dyslipidemia in the...

journal_title：Nutrition & diabetes

authors： Cirera S,Taşöz E,Juul Jacobsen M,Schumacher-Petersen C,Østergaard Christoffersen B,Kaae Kirk R,Pagh Ludvigsen T,Hvid H,Duelund Pedersen H,Høier Olsen L,Fredholm M

更新日期：2020-03-23 00:00:00

abstract：OBJECTIVES:We aim to validate the effects of glucose-dependent insulinotropic polypeptide (GIP) on fat distribution and glucose metabolism in Han Chinese populations. METHODS:We genotyped six tag single-nucleotide polymorphisms (SNPs) of GIP and four tag SNPs of glucose-dependent insulinotropic polypeptide receptor (G...

journal_title：Nutrition & diabetes

authors： Wang T,Ma X,Tang T,Higuchi K,Peng D,Zhang R,Chen M,Yan J,Wang S,Yan D,He Z,Jiang F,Bao Y,Jia W,Ishida K,Hu C

更新日期：2017-05-22 00:00:00

abstract：OBJECTIVE:To examine the social and behavioural correlates of metabolic phenotypes during 'at-risk' and 'case' stages of the metabolic disease continuum. DESIGN:Cross-sectional study of a random population sample. PARTICIPANTS:A total of 718 community-dwelling adults (57% female), aged 18-92 years from a regional Sou...

journal_title：Nutrition & diabetes

authors： Haren MT,Misan G,Grant JF,Buckley JD,Howe PR,Taylor AW,Newbury J,McDermott RA

更新日期：2012-01-16 00:00:00

abstract：:Metabolic syndrome (MS) is a condition that includes obesity, insulin resistance, dyslipidemias among other, abnormalities that favors type 2 Diabetes Mellitus (T2DM) and cardiovascular diseases development. Three main diet-induced metabolic syndrome models in rats exist: High carbohydrate diet (HCHD), high fat diet (...

journal_title：Nutrition & diabetes

authors： Rodríguez-Correa E,González-Pérez I,Clavel-Pérez PI,Contreras-Vargas Y,Carvajal K

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND/OBJECTIVES:Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal pre-pregnancy overweight (body mass index (BMI) ≥ 25 kg/m2) or GDM are associated with dietary quality or ...

journal_title：Nutrition & diabetes

authors： Kaseva N,Vääräsmäki M,Matinolli HM,Sipola M,Tikanmäki M,Kanerva N,Heinonen K,Lano A,Wolke D,Andersson S,Järvelin MR,Räikkönen K,Eriksson JG,Männistö S,Kajantie E

更新日期：2020-07-23 00:00:00