Abstract：
:For convenience, health practitioners and clinicians are inclined to classify people/patients as overweight or obese based on body mass index (BMI) cutoff points of 25 and 30 kg m(-2) respectively, irrespective of age and gender. The purpose of the current study was to identity whether, for the same levels of adiposity, BMI is the same across different age groups and gender. A two-way ANCOVA revealed significant differences in BMI between different age groups and gender (plus an interaction), using body fat (%) as the covariate, data taken from a random sample of the English population (n=2993). Younger people had greater BMI than older people for the same levels of adiposity (differences ranged by 4 BMI units for males, and 3 BMI units for females). In conclusion, if BMI thresholds for overweight (BMI=25 kg m(-2)) and obese (BMI=30 kg m(-2)) are to reflect the same levels of adiposity across all gender and age groups within a population, then age- and gender-specific BMI adjustments outlined here are necessary to more accurately/fairly reflect the same critical levels of adiposity.
journal_name
Nutr Diabetesjournal_title
Nutrition & diabetesauthors
Nevill AM,Metsios GSdoi
10.1038/nutd.2015.36subject
Has Abstractpub_date
2015-11-30 00:00:00pages
e186issn
2044-4052pii
nutd201536journal_volume
5pub_type
杂志文章abstract：:Globally type 1 diabetes incidence is increasing. It is widely accepted that the pathophysiology of type 1 diabetes is influenced by environmental factors in people with specific human leukocyte antigen haplotypes. We propose that a complex interplay between dietary triggers, permissive gut factors and potentially oth...
journal_title：Nutrition & diabetes
pub_type： 杂志文章,评审
doi：10.1038/nutd.2017.16
更新日期：2017-05-15 00:00:00
abstract：OBJECTIVES:The prevalence of obesity and diabetes in the Middle East is among the highest in the world. Valid measures of abdominal adiposity are essential to understanding the metabolic consequences of obesity. Dual-energy X-ray absorptiometry (DXA) is increasingly being utilised to assess body composition in populati...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2016.38
更新日期：2017-01-09 00:00:00
abstract：BACKGROUND:Plasma concentration of the methyl donor S-adenosylmethionine (SAM) is linearly associated with body mass index (BMI) and fat mass. As SAM is a high-energy compound and a sensor of cellular nutrient status, we hypothesized that SAM would increase with overfeeding. METHODS:Forty normal to overweight men and ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2015.44
更新日期：2016-01-25 00:00:00
abstract：OBJECTIVES:We aim to validate the effects of glucose-dependent insulinotropic polypeptide (GIP) on fat distribution and glucose metabolism in Han Chinese populations. METHODS:We genotyped six tag single-nucleotide polymorphisms (SNPs) of GIP and four tag SNPs of glucose-dependent insulinotropic polypeptide receptor (G...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2017.28
更新日期：2017-05-22 00:00:00
abstract：OBJECTIVE:In recent years, people have changed their eating habits, and high-fructose-containing bubble tea has become very popular. High-fructose intake has been suggested to be a key factor that induces non-alcoholic fatty liver disease (NAFLD). Kefir, a fermented milk product composed of microbial symbionts, has dem...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2016.49
更新日期：2016-12-12 00:00:00
abstract：BACKGROUND/OBJECTIVES:The current obesity epidemic has spurred exploration of the developmental origin of adult heath and disease. A mother's dietary choices and health can affect both the early wellbeing and lifelong disease-risk of the offspring. SUBJECTS/METHODS:To determine if changes in the mother's diet and adip...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-018-0027-z
更新日期：2018-04-25 00:00:00
abstract：BACKGROUND:Individuals who focused on calorie counting lost more weight than those who focused on increasing vegetable and fruit (V&F) intake in a weight loss program. We now present serum carotenoid data (biomarkers of V&F intake) from both groups and test whether these biomarkers correlate with changes in weight and ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2012.22
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Aging is associated with many physiological alterations such as changes in metabolism, food intake and brain dysfunction. Possible ways to correct age-related brain dysfunction using dietary treatments still remains undeveloped. The aim of our research was to investigate whether long-term dietary ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2015.13
更新日期：2015-06-15 00:00:00
abstract：BACKGROUND/OBJECTIVES:Sleep duration influences weight change in children and young adults, but there is less evidence in middle-aged, and, in particular, older adults. We assessed associations between sleep duration, daytime napping and sleep disturbances, respectively, with change of weight and waist circumference in...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2016.32
更新日期：2016-08-15 00:00:00
abstract：OBJECTIVE:The aim of dietary modification, as a cornerstone of type 2 diabetes (T2DM) management, is to optimise metabolic control and overall health. This study describes food and nutrient intake in a sample of adults with T2DM, and compares this to recommendations, and to intake in age, sex, body mass index (BMI) and...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2014.2
更新日期：2014-02-03 00:00:00
abstract：BACKGROUND/OBJECTIVES:High dietary fibre intakes may protect against obesity by influencing colonic fermentation and the colonic microbiota. Though, recent studies suggest that increased colonic fermentation contributes to adiposity. Diet influences the composition of the gut microbiota. Previous research has not evalu...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2014.23
更新日期：2014-06-30 00:00:00
abstract：BACKGROUND:The global prevalence of diabetes is high and rapidly increasing. Some previous studies have found that vegetarians might have a lower risk of diabetes than non-vegetarians. OBJECTIVE:We examined the association between vegetarianism and risk of hospitalisation or death with diabetes in a large, prospective...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-019-0074-0
更新日期：2019-02-25 00:00:00
abstract：OBJECTIVE:There is a link between joint and gut inflammation of unknown etiology in arthritis. Existing research indicates that regular consumption of high-fructose corn syrup sweetened (HFCS) soft drinks, but not diet soft drinks, may be associated with increased risk of seropositive rheumatoid arthritis (RA) in women...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2016.7
更新日期：2016-03-07 00:00:00
abstract：BACKGROUND:Aerobic exercise training is known to have beneficial effects on whole-body glucose metabolism in people with type 2 diabetes (T2D). The responses of the liver to such training are less well understood. The purpose of this study was to determine the effect of aerobic exercise training on splanchnic glucose u...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-019-0090-0
更新日期：2019-09-02 00:00:00
abstract：BACKGROUND:Individuals with type 2 diabetes (DM2) may be less successful at achieving therapeutic weight loss than their counterparts without diabetes. This study compares weight loss in a cohort of adults with DM2 or high blood sugar (D/HBS) to a cohort of adults without D/HBS. All were overweight/obese and following ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2017.32
更新日期：2017-07-10 00:00:00
abstract：:The sympathetic nervous system (SNS) regulates energy homeostasis in part by governing fatty acid liberation from adipose tissue. We first examined whether SNS activity toward discrete adipose depots changes in response to a weight loss diet in mice. We found that SNS activity toward each adipose depot is unique in ti...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2017.13
更新日期：2017-04-10 00:00:00
abstract：BACKGROUND:The role of resistant starch (RS) in glucose, insulin, insulin resistance or sensitivity, and lipid parameters have been reported in several studies and remained controversial. A pooled analysis which assessed these parameters has not been performed. Thus, we conducted a meta-analysis to sum up existing evid...
journal_title：Nutrition & diabetes
pub_type： 杂志文章,meta分析
doi：10.1038/s41387-019-0086-9
更新日期：2019-06-05 00:00:00
abstract：:Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a common complication in patients experiencing end-stage renal disease (ESRD). It includes abnormalities in bone and mineral metabolism and vascular calcification. Hyperphosphatemia is a major risk factor leading to morbidity and mortality in patients with ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章,评审
doi：10.1038/s41387-019-0080-2
更新日期：2019-04-03 00:00:00
abstract：:Coffee consumption has been reported to reduce the risk of type 2 diabetes in experimental and epidemiological studies. This anti-diabetic effect of coffee may be attributed to its high content in polyphenols especially caffeic acid and chlorogenic acid. However, the association between plasma coffee polyphenols and d...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2016.19
更新日期：2016-06-06 00:00:00
abstract：BACKGROUNDS:Mitochondria plays a critical role in the development and pathogenesis of nonalcoholic fatty liver disease (NAFLD). Neohesperidin (NHP) could lower blood glucose and prevent obesity in mice. However, the direct effect of NHP on hepatic steatosis has not been reported. METHODS:Mice were fed with either a ch...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-020-00130-3
更新日期：2020-08-05 00:00:00
abstract：BACKGROUND/OBJECTIVES:Vegetarian diets are inversely associated with diabetes in Westerners but their impact on Asians-whose pathophysiology differ from Westerners-is unknown. We aim to investigate the association between a vegetarian diet, change in dietary patterns and diabetes risk in a Taiwanese Buddhist population...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-018-0022-4
更新日期：2018-03-09 00:00:00
abstract：OBJECTIVE:The gut microbiota contribute otherwise impossible metabolic functions to the human host. Shifts in the relative proportions of gut microbial communities in adults have been correlated with intestinal disease and have been associated with obesity. The aim of this study was to elucidate differences in gut micr...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2011.8
更新日期：2011-07-18 00:00:00
abstract：OBJECTIVES:Obesity is associated with hyperactivation of the reward system for high-calorie (HC) versus low-calorie (LC) food cues, which encourages unhealthy food selection and overeating. However, the extent to which this hyperactivation can be reversed is uncertain, and to date there has been no demonstration of cha...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2014.26
更新日期：2014-09-01 00:00:00
abstract：:Obesity and related complications are major health burdens. Almost 700 million adults are currently obese globally and the prevalence is predicted to rise towards 2030. The sudden change of lifestyle with physical inactivity and excessive calorie intake undoubtedly have a major part of the epidemic development; howeve...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2012.9
更新日期：2012-07-30 00:00:00
abstract：AIM:The purpose of this study was to investigate the association of dietary patterns with the risk of insulin resistance (IR), diabetes mellitus (DM), and central obesity in China. METHODS:We performed a cross-sectional study on 1432 participants, aged 40-65 years in Hangzhou, Zhejiang province, China. Dietary intake ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-020-0120-y
更新日期：2020-06-04 00:00:00
abstract：BACKGROUND AND DESIGN:Adiponectin is an adipokine secreted primarily from adipose tissue that can influence circulating plasma glucose and lipid levels through multiple mechanisms involving a variety of organs. In humans, reduced plasma adiponectin levels induced by obesity are associated with insulin resistance and ty...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2012.18
更新日期：2012-09-10 00:00:00
abstract：OBJECTIVE:Obesity in the United States is highly prevalent, approaching 60% for black women. We investigated whether nutrition education sessions at the work place added to internet-based wellness information and exercise resources would facilitate weight and fat mass loss in a racially diverse population of overweight...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2013.39
更新日期：2013-12-23 00:00:00
abstract：OBJECTIVE:Along with the increasing prevalence of obesity and related diseases, particularly atherosclerotic diseases, metabolic syndrome (MetS) is now a common and major public health issue in many countries around the world. Adiponectin, a protein secreted by the adipose tissue, has become recognized as a key player ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2011.13
更新日期：2011-10-10 00:00:00
abstract：:Obesity is associated with inflammatory macrophages in insulin responsive tissues and the resulting inflammatory response is a major contributor to insulin resistance. In insulin-producing pancreatic islets, the intra-islet accumulation of macrophages is observed in patients of type 2 diabetes (T2D), but such has not ...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/s41387-019-0103-z
更新日期：2019-12-02 00:00:00
abstract：OBJECTIVE:Microfibrillar-associated protein 5 (MFAP5) is an extracellular matrix (ECM) glycoprotein, which is colocalized with microfibrils in elastin networks. Its function in adipose tissue (AT) is not known. We have recently shown that the expression of MFAP5 is downregulated in AT along with weight reduction (WR) i...
journal_title：Nutrition & diabetes
pub_type： 杂志文章
doi：10.1038/nutd.2011.10
更新日期：2011-08-29 00:00:00
